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Efficacy, Safety, and Predictors of Direct-acting antivirals in Hepatitis C Virus Patients with Heterogeneous Liver Diseases.

De Pace V, Morelli MC, Ravaioli M, Maggi F, Galli S, Vero V, Re MC, Cescon M, Pistello M.

New Microbiol. 2019 Oct 14;42(4). [Epub ahead of print]


Highly chemoselective difluoromethylative homologation of iso(thio)cyanates: expeditious access to unprecedented α,α-difluoro(thio)amides.

Miele M, D'Orsi R, Sridharan V, Holzer W, Pace V.

Chem Commun (Camb). 2019 Oct 11. doi: 10.1039/c9cc06929a. [Epub ahead of print]


Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent.

Miele M, Citarella A, Micale N, Holzer W, Pace V.

Org Lett. 2019 Oct 10. doi: 10.1021/acs.orglett.9b03024. [Epub ahead of print]


A Combination of Pharmacophore and Docking-based Virtual Screening to Discover new Tyrosinase Inhibitors.

Vittorio S, Seidel T, Germanò MP, Gitto R, Ielo L, Garon A, Rapisarda A, Pace V, Langer T, De Luca L.

Mol Inform. 2019 Sep 11. doi: 10.1002/minf.201900054. [Epub ahead of print]


Radiographic, Bone Densitometry and Clinic Outcomes Assessments in Femoral Shaft Fractures Fixed by Plating or Locking Retrograde Nail.

Rollo G, Bisaccia M, Rinonapoli G, Caraffa A, Pace V, Irimia JC, de Cruto E, Bisaccia O, Pica G, Tarantino D, Meccariello L.

Med Arch. 2019 Jun;73(3):195-200. doi: 10.5455/medarh.2019.73.195-200.


Direct Access to 9-Chloro-1H-benzo[b]furo[3,4-e]azepin-1-ones via Palladium(II)-Catalyzed Intramolecular syn-Oxypalladation/Olefin Insertion/sp2-C-H Bond Activation Cascade.

Karuppasamy M, Vachan BS, Vinoth P, Muthukrishnan I, Nagarajan S, Ielo L, Pace V, Banik S, Maheswari CU, Sridharan V.

Org Lett. 2019 Aug 2;21(15):5784-5788. doi: 10.1021/acs.orglett.9b01482. Epub 2019 Jul 16.


A new plate design to treat displaced 3-4 parts proximal humeral fractures in comparison to the most tested and used plate: clinical and radiographic study.

Rollo G, Porcellini G, Rotini R, Bisaccia M, Pichierri P, Paladini P, Guerra E, De Cruto E, Franzese R, Grubor P, Pace V, Meccariello L.

Med Glas (Zenica). 2019 Aug 1;16(2). doi: 10.17392/1033-19. [Epub ahead of print]


The challenge of nonunion and malunion in distal femur surgical revision.

Rollo G, Pichierri P, Grubor P, Marsilio A, Bisaccia M, Grubor M, Pace V, Lanzetti RM, Giaracuni M, Filipponi M, Meccariello L.

Med Glas (Zenica). 2019 Aug 1;16(2). doi: 10.17392/1016-19. [Epub ahead of print]


The histological assessment of liver fibrosis in grafts from extended criteria donors predicts the outcome after liver transplantation: A retrospective study.

D'Errico A, Riefolo M, Serenari M, De Pace V, Santandrea G, Monica M, de Cillia C, Ravaioli M, Cescon M, Vasuri F; Pathology Unit for organ safety of the S. Orsola-Malpighi Hospital Bologna: Alberto Bagni Giacomo Caprara Benedetta Fabbrizio Deborah Malvi Maria Giulia Pirini Maria Lucia Tardio.

Dig Liver Dis. 2019 May 30. pii: S1590-8658(19)30592-4. doi: 10.1016/j.dld.2019.05.013. [Epub ahead of print]


Enhanced recovery after surgery (ERAS) in hip and knee replacement surgery: description of a multidisciplinary program to improve management of the patients undergoing major orthopedic surgery.

Frassanito L, Vergari A, Nestorini R, Cerulli G, Placella G, Pace V, Rossi M.

Musculoskelet Surg. 2019 May 3. doi: 10.1007/s12306-019-00603-4. [Epub ahead of print]


Palladium-Catalyzed Regioselective Syn-Chloropalladation-Olefin Insertion-Oxidative Chlorination Cascade: Synthesis of Dichlorinated Tetrahydroquinolines.

Vinoth P, Karuppasamy M, Vachan BS, Muthukrishnan I, Maheswari CU, Nagarajan S, Pace V, Roller A, Bhuvanesh N, Sridharan V.

Org Lett. 2019 May 3;21(9):3465-3469. doi: 10.1021/acs.orglett.9b01295. Epub 2019 Apr 19.


17O NMR and 15N NMR chemical shifts of sterically-hindered amides: ground-state destabilization in amide electrophilicity.

Pace V, Holzer W, Ielo L, Shi S, Meng G, Hanna M, Szostak R, Szostak M.

Chem Commun (Camb). 2019 Apr 9;55(30):4423-4426. doi: 10.1039/c9cc01402k.


Delayed Presentation of a Symptomatic Psoas Hematoma Following Lumbar Vertebral Kyphoplasty for Myeloma: A Case Report.

Pace V, Bhagawati D, Park C, Molloy S.

J Orthop Case Rep. 2018 Nov-Dec;8(6):74-78. doi: 10.13107/jocr.2250-0685.1266.


Long term results of down-staging and liver transplantation for patients with hepatocellular carcinoma beyond the conventional criteria.

Ravaioli M, Odaldi F, Cucchetti A, Trevisani F, Piscaglia F, De Pace V, Bertuzzo VR, Neri F, Golfieri R, Cappelli A, D'Errico A, Cescon M, Del Gaudio M, Fallani G, Siniscalchi A, Morelli MC, Ciccarese F, Di Marco M, Farinati F, Giannini EG, Pinna AD.

Sci Rep. 2019 Mar 7;9(1):3781. doi: 10.1038/s41598-019-40543-4.


Sustainable Asymmetric Organolithium Chemistry: Enantio- and Chemoselective Acylations through Recycling of Solvent, Sparteine, and Weinreb "Amine".

Monticelli S, Holzer W, Langer T, Roller A, Olofsson B, Pace V.

ChemSusChem. 2019 Mar 21;12(6):1147-1154. doi: 10.1002/cssc.201802815. Epub 2019 Feb 13.


Modular and Chemoselective Strategy for the Direct Access to α-Fluoroepoxides and Aziridines via the Addition of Fluoroiodomethyllithium to Carbonyl-Like Compounds.

Monticelli S, Colella M, Pillari V, Tota A, Langer T, Holzer W, Degennaro L, Luisi R, Pace V.

Org Lett. 2019 Jan 18;21(2):584-588. doi: 10.1021/acs.orglett.8b04001. Epub 2019 Jan 2.


Telescoped, Divergent, Chemoselective C1 and C1-C1 Homologation of Imine Surrogates: Access to Quaternary Chloro- and Halomethyl-Trifluoromethyl Aziridines.

Ielo L, Touqeer S, Roller A, Langer T, Holzer W, Pace V.

Angew Chem Int Ed Engl. 2019 Feb 18;58(8):2479-2484. doi: 10.1002/anie.201812525. Epub 2019 Jan 24.


The Advantages of Type III Scaphoid Nonunion Advanced Collapse (SNAC) Treatment With Partial Carpal Arthrodesis in the Dominant Hand: Results of 5-year Follow-up.

Rollo G, Bisaccia M, Irimia JC, Rinonapoli G, Pasquino A, Tomarchio A, Roca L, Pace V, Pichierri P, Giaracuni M, Meccariello L.

Med Arch. 2018 Oct;72(4):253-256. doi: 10.5455/medarh.2018.72.253-256.


Percutaneous screws CT guided to fix sacroiliac joint in tile C pelvic injury. Outcomes at 5 years of follow-up.

Falzarano G, Rollo G, Bisaccia M, Pace V, Lanzetti RM, Garcia-Prieto E, Pichierri P, Meccariello L.

SICOT J. 2018;4:52. doi: 10.1051/sicotj/2018047. Epub 2016 Nov 27.


Skin lesion monitoring at slaughter on heavy pigs (170 kg): Welfare indicators and ham defects.

Bottacini M, Scollo A, Edwards SA, Contiero B, Veloci M, Pace V, Gottardo F.

PLoS One. 2018 Nov 12;13(11):e0207115. doi: 10.1371/journal.pone.0207115. eCollection 2018.


LncRNAs as novel players in hepatocellular carcinoma recurrence.

Gramantieri L, Baglioni M, Fornari F, Laginestra MA, Ferracin M, Indio V, Ravaioli M, Cescon M, De Pace V, Leoni S, Coadă CA, Negrini M, Bolondi L, Giovannini C.

Oncotarget. 2018 Oct 12;9(80):35085-35099. doi: 10.18632/oncotarget.26202. eCollection 2018 Oct 12.


Chemoselective reduction of isothiocyanates to thioformamides mediated by the Schwartz reagent.

de la Vega-Hernández K, Senatore R, Miele M, Urban E, Holzer W, Pace V.

Org Biomol Chem. 2019 Feb 13;17(7):1970-1978. doi: 10.1039/c8ob02312c.


Design, Synthesis, and Pharmacological Evaluation of Novel β2/3 Subunit-Selective γ-Aminobutyric Acid Type A (GABAA) Receptor Modulators.

Stadler M, Monticelli S, Seidel T, Luger D, Salzer I, Boehm S, Holzer W, Schwarzer C, Urban E, Khom S, Langer T, Pace V, Hering S.

J Med Chem. 2019 Jan 10;62(1):317-341. doi: 10.1021/acs.jmedchem.8b00859. Epub 2018 Oct 23.


Cyclopentyl Methyl Ether: An Elective Ecofriendly Ethereal Solvent in Classical and Modern Organic Chemistry.

Azzena U, Carraro M, Pisano L, Monticelli S, Bartolotta R, Pace V.

ChemSusChem. 2019 Jan 10;12(1):40-70. doi: 10.1002/cssc.201801768. Epub 2018 Nov 20. Review.


Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents.

Rui M, Rossino G, Coniglio S, Monteleone S, Scuteri A, Malacrida A, Rossi D, Catenacci L, Sorrenti M, Paolillo M, Curti D, Venturini L, Schepmann D, Wünsch B, Liedl KR, Cavaletti G, Pace V, Urban E, Collina S.

Eur J Med Chem. 2018 Oct 5;158:353-370. doi: 10.1016/j.ejmech.2018.09.010. Epub 2018 Sep 8.


Easy as one, two, three.

Castoldi L, Pace V.

Nat Chem. 2018 Nov;10(11):1081-1082. doi: 10.1038/s41557-018-0139-z. No abstract available.


A multi-cellular 3D bioprinting approach for vascularized heart tissue engineering based on HUVECs and iPSC-derived cardiomyocytes.

Maiullari F, Costantini M, Milan M, Pace V, Chirivì M, Maiullari S, Rainer A, Baci D, Marei HE, Seliktar D, Gargioli C, Bearzi C, Rizzi R.

Sci Rep. 2018 Sep 10;8(1):13532. doi: 10.1038/s41598-018-31848-x.


What are the main palliative care symptoms and concerns of older people with multimorbidity?-a comparative cross-sectional study using routinely collected Phase of Illness, Australia-modified Karnofsky Performance Status and Integrated Palliative Care Outcome Scale data.

Nicholson C, Davies JM, George R, Smith B, Pace V, Harris L, Ross J, Noble J, Hansford P, Murtagh FEM.

Ann Palliat Med. 2018 Oct;7(Suppl 3):S164-S175. doi: 10.21037/apm.2018.06.07. Epub 2018 Jul 18.


Homologation of halostannanes with carbenoids: a convenient and straightforward one-step access to α-functionalized organotin reagents.

Touqeer S, Castoldi L, Langer T, Holzer W, Pace V.

Chem Commun (Camb). 2018 Sep 6;54(72):10112-10115. doi: 10.1039/c8cc04786c.


Heterotopic auxiliary segment 2-3 liver transplantation with delayed total hepatectomy: New strategies for nonresectable colorectal liver metastases.

Ravaioli M, Fallani G, Cescon M, Prosperi E, De Pace V, Siniscalchi A, Sangiorgi G, Ferracin M, Ardizzoni A, Morelli MC, Garajová I.

Surgery. 2018 Sep;164(3):601-603. doi: 10.1016/j.surg.2018.05.021. Epub 2018 Jul 2. No abstract available.


A practical guide for using lithium halocarbenoids in homologation reactions.

Monticelli S, Rui M, Castoldi L, Missere G, Pace V.

Monatsh Chem. 2018;149(7):1285-1291. doi: 10.1007/s00706-018-2232-9. Epub 2018 Jun 11.


An unusual thionyl chloride-promoted C-C bond formation to obtain 4,4'-bipyrazolones.

Eller GA, Vilkauskaitė G, Šačkus A, Martynaitis V, Mamuye AD, Pace V, Holzer W.

Beilstein J Org Chem. 2018 Jun 4;14:1287-1292. doi: 10.3762/bjoc.14.110. eCollection 2018.


Preliminary experience of sequential use of normothermic and hypothermic oxygenated perfusion for donation after circulatory death kidney with warm ischemia time over the conventional criteria - a retrospective and observational study.

Ravaioli M, De Pace V, Comai G, Capelli I, Baraldi O, D'Errico A, Bertuzzo VR, Del Gaudio M, Zanfi C, D'Arcangelo GL, Cuna V, Siniscalchi A, Sangiorgi G, La Manna G.

Transpl Int. 2018 Nov;31(11):1233-1244. doi: 10.1111/tri.13311. Epub 2018 Jul 20.


Homologation chemistry with nucleophilic α-substituted organometallic reagents: chemocontrol, new concepts and (solved) challenges.

Castoldi L, Monticelli S, Senatore R, Ielo L, Pace V.

Chem Commun (Camb). 2018 Jun 19;54(50):6692-6704. doi: 10.1039/c8cc02499e.


Surface functionalization of acrylic based photocrosslinkable resin for 3D printing applications.

Ronca A, Maiullari F, Milan M, Pace V, Gloria A, Rizzi R, De Santis R, Ambrosio L.

Bioact Mater. 2017 Apr 21;2(3):131-137. doi: 10.1016/j.bioactmat.2017.04.002. eCollection 2017 Sep.


Tissue miRNA 483-3p expression predicts tumor recurrence after surgical resection in histologically advanced hepatocellular carcinomas.

Vasuri F, Fittipaldi S, De Pace V, Gramantieri L, Bertuzzo V, Cescon M, Pinna AD, Fiorentino M, D'Errico A, Ravaioli M.

Oncotarget. 2018 Apr 3;9(25):17895-17905. doi: 10.18632/oncotarget.24860. eCollection 2018 Apr 3.


Expeditious and Chemoselective Synthesis of α-Aryl and α-Alkyl Selenomethylketones via Homologation Chemistry.

Senatore R, Castoldi L, Ielo L, Holzer W, Pace V.

Org Lett. 2018 May 4;20(9):2685-2688. doi: 10.1021/acs.orglett.8b00896. Epub 2018 Apr 17.


α-Arylamino Diazoketones: Diazomethane-Loading Controlled Synthesis, Spectroscopic Investigations, and Structural X-ray Analysis.

Castoldi L, Ielo L, Holzer W, Giester G, Roller A, Pace V.

J Org Chem. 2018 Apr 20;83(8):4336-4347. doi: 10.1021/acs.joc.7b03134. Epub 2018 Apr 3.


Introduction of clerking pro forma for surgical spinal patients at the Royal National Orthopaedic Hospital NHS Trust (London): an audit cycle.

Pace V, Farooqi O, Kennedy J, Park C, Cowan J.

Postgrad Med J. 2018 May;94(1111):305-307. doi: 10.1136/postgradmedj-2017-135498. Epub 2018 Mar 14.


Givinostat reduces adverse cardiac remodeling through regulating fibroblasts activation.

Milan M, Pace V, Maiullari F, Chirivì M, Baci D, Maiullari S, Madaro L, Maccari S, Stati T, Marano G, Frati G, Puri PL, De Falco E, Bearzi C, Rizzi R.

Cell Death Dis. 2018 Jan 25;9(2):108. doi: 10.1038/s41419-017-0174-5.


Strategies to Restore Adenosine Triphosphate (ATP) Level After More than 20 Hours of Cold Ischemia Time in Human Marginal Kidney Grafts.

Ravaioli M, Baldassare M, Vasuri F, Pasquinelli G, Laggetta M, Valente S, De Pace V, Neri F, Siniscalchi A, Zanfi C, Bertuzzo VR, Caraceni P, Trerè D, Longobardi P, Pinna AD.

Ann Transplant. 2018 Jan 12;23:34-44.


Are there any relations among transplant centre volume, surgical technique and anatomy for donor graft selection? Ten-year multicentric Italian experience on mini-invasive living donor nephrectomy.

Ravaioli M, Capocasale E, Furian L, De Pace V, Iaria M, Spagnoletti G, Salerno MP, Giacomoni A, De Carlis L, Di Bella C, Rostand NM, Boschiero L, Pasquale G, Bosio A, Collini A, Carmellini M, Airoldi A, Bondonno G, Ditonno P, Impedovo SV, Beretta C, Giussani A, Socci C, Parolini DC, Abelli M, Ticozzelli E, Baccarani U, Adani GL, Caputo F, Buscemi B, Frongia M, Solinas A, Gruttadauria S, Spada M, Pinna AD, Romagnoli J.

Nephrol Dial Transplant. 2017 Dec 1;32(12):2126-2131. doi: 10.1093/ndt/gfx285.


Successful Dual Kidney Transplantation After Hypothermic Oxygenated Perfusion of Discarded Human Kidneys.

Ravaioli M, De Pace V, Comai G, Busutti M, Del Gaudio M, Amaduzzi A, Cucchetti A, Siniscalchi A, La Manna G, D'Errico AAD, Pinna AD.

Am J Case Rep. 2017 Sep 20;18:1009-1013.


The role of metronomic capecitabine for treatment of recurrent hepatocellular carcinoma after liver transplantation.

Ravaioli M, Cucchetti A, Pinna AD, De Pace V, Neri F, Barbera MA, Maroni L, Frega G, Palloni A, De Lorenzo S, Ripoli MC, Pantaleo MA, Cescon M, Del Gaudio M, Brandi G.

Sci Rep. 2017 Sep 12;7(1):11305. doi: 10.1038/s41598-017-11810-z.


Exploiting a "Beast" in Carbenoid Chemistry: Development of a Straightforward Direct Nucleophilic Fluoromethylation Strategy.

Parisi G, Colella M, Monticelli S, Romanazzi G, Holzer W, Langer T, Degennaro L, Pace V, Luisi R.

J Am Chem Soc. 2017 Oct 4;139(39):13648-13651. doi: 10.1021/jacs.7b07891. Epub 2017 Sep 15.


Evidence and isolation of tetrahedral intermediates formed upon the addition of lithium carbenoids to Weinreb amides and N-acylpyrroles.

Castoldi L, Holzer W, Langer T, Pace V.

Chem Commun (Camb). 2017 Aug 22;53(68):9498-9501. doi: 10.1039/c7cc05215d.


Efficient Access to All-Carbon Quaternary and Tertiary α-Functionalized Homoallyl-type Aldehydes from Ketones.

Pace V, Castoldi L, Mazzeo E, Rui M, Langer T, Holzer W.

Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12677-12682. doi: 10.1002/anie.201706236. Epub 2017 Sep 1.


From six thousand transaminases level to three hundred after liver transplantation: a new era seems to be open.

Ravaioli M, De Pace V, Pinna AD.

Updates Surg. 2017 Dec;69(4):549-550. doi: 10.1007/s13304-017-0466-4. Epub 2017 Jun 9. No abstract available.


A greener and efficient access to substituted four- and six-membered sulfur-bearing heterocycles.

Parisi G, Degennaro L, Carlucci C, de Candia M, Mastrorilli P, Roller A, Holzer W, Altomare CD, Pace V, Luisi R.

Org Biomol Chem. 2017 Jun 14;15(23):5000-5015. doi: 10.1039/c7ob00846e.


Synthesis of tetrasubstituted pyrazoles containing pyridinyl substituents.

Jansa J, Schmidt R, Mamuye AD, Castoldi L, Roller A, Pace V, Holzer W.

Beilstein J Org Chem. 2017 May 12;13:895-902. doi: 10.3762/bjoc.13.90. eCollection 2017.

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