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Items: 1 to 50 of 201

1.

Histological features of malignancy correlate with growth patterns and patient outcome in lung adenocarcinoma.

Mäkinen JM, Laitakari K, Johnson S, Mäkitaro R, Bloigu R, Pääkkö P, Lappi-Blanco E, Kaarteenaho R.

Histopathology. 2017 Sep;71(3):425-436. doi: 10.1111/his.13236. Epub 2017 Jun 16.

PMID:
28401582
2.

Mesotheliomas show higher hyaluronan positivity around tumor cells than metastatic pulmonary adenocarcinomas.

Törrönen K, Soini Y, Pääkkö P, Parkkinen J, Sironen R, Rilla K.

Histol Histopathol. 2016 Oct;31(10):1113-22. doi: 10.14670/HH-11-740. Epub 2016 Feb 25.

PMID:
26912058
3.

Claudin-5 is associated with elevated TATI and CA125 levels in mucinous ovarian borderline tumors.

Nissi R, Talvensaari-Mattila A, Kuvaja P, Pääkkö P, Soini Y, Santala M.

Anticancer Res. 2015 Feb;35(2):973-6.

PMID:
25667483
4.

Slug is associated with poor survival in squamous cell carcinoma of the lung.

Merikallio H, T TT, Pääkkö P, Mäkitaro R, Kaarteenaho R, Lehtonen S, Salo S, Salo T, Harju T, Soini Y.

Int J Clin Exp Pathol. 2014 Aug 15;7(9):5846-54. eCollection 2014.

5.

GASC1 expression in lung carcinoma is associated with smoking and prognosis of squamous cell carcinoma.

Uimonen K, Merikallio H, Pääkkö P, Harju T, Mannermaa A, Palvimo J, Kosma VM, Soini Y.

Histol Histopathol. 2014 Jun;29(6):797-804. doi: 10.14670/HH-29.797. Epub 2013 Dec 27.

PMID:
24371038
6.

[Pathology is much more than tumor diagnostics].

Karttunen T, Pääkkö P.

Duodecim. 2013;129(10):1089-96. Review. Finnish.

PMID:
23767139
7.

Snail promotes an invasive phenotype in lung carcinoma.

Merikallio H, Turpeenniemi-Hujanen T, Pääkkö P, Mäkitaro R, Riitta K, Salo S, Salo T, Harju T, Soini Y.

Respir Res. 2012 Nov 17;13:104. doi: 10.1186/1465-9921-13-104.

8.

Expression of snail, twist, and Zeb1 in malignant mesothelioma.

Merikallio H, Pääkkö P, Salmenkivi K, Kinnula V, Harju T, Soini Y.

APMIS. 2013 Jan;121(1):1-10. doi: 10.1111/j.1600-0463.2012.02931.x. Epub 2012 Jun 26.

PMID:
23030626
9.

Elevated messenger RNA expression and plasma protein levels of osteopontin and matrix metalloproteinase types 2 and 9 in patients with ascending aortic aneurysms.

Huusko T, Salonurmi T, Taskinen P, Liinamaa J, Juvonen T, Pääkkö P, Savolainen M, Kakko S.

J Thorac Cardiovasc Surg. 2013 Apr;145(4):1117-1123. doi: 10.1016/j.jtcvs.2012.04.008. Epub 2012 May 7.

10.

Tumor tissue inhibitor of metalloproteinases-1 (TIMP-1) in hormone-independent breast cancer might originate in stromal cells, and improves stratification of prognosis together with nodal status.

Kuvaja P, Hulkkonen S, Pasanen I, Soini Y, Lehtonen S, Talvensaari-Mattila A, Pääkkö P, Kaakinen M, Autio-Harmainen H, Hurskainen T, Lehenkari P, Turpeenniemi-Hujanen T.

Exp Cell Res. 2012 Jun 10;318(10):1094-103. doi: 10.1016/j.yexcr.2012.03.009. Epub 2012 Mar 23.

PMID:
22465225
11.

[Congenital ciliary dysfunction in children].

Korppi M, Dunder T, Remes S, Sjöström PM, Holm T, Vähäsarja V, Jartti T, Pääkkö P, Kajosaari M.

Duodecim. 2011;127(21):2294-302. Review. Finnish.

PMID:
22204144
12.

Claudins 10 and 18 are predominantly expressed in lung adenocarcinomas and in tumors of nonsmokers.

Merikallio H, Pääkkö P, Harju T, Soini Y.

Int J Clin Exp Pathol. 2011;4(7):667-73. Epub 2011 Sep 27.

13.

Nuclear factor erythroid-derived 2-like 2 (Nrf2) and DJ1 are prognostic factors in lung cancer.

Merikallio H, Pääkkö P, Kinnula VL, Harju T, Soini Y.

Hum Pathol. 2012 Apr;43(4):577-84. doi: 10.1016/j.humpath.2011.05.024. Epub 2011 Sep 23.

PMID:
21943684
14.

Specific TP53 mutations predict aggressive phenotype in head and neck squamous cell carcinoma: a retrospective archival study.

Peltonen JK, Vähäkangas KH, Helppi HM, Bloigu R, Pääkkö P, Turpeenniemi-Hujanen T.

Head Neck Oncol. 2011 Apr 22;3:20. doi: 10.1186/1758-3284-3-20.

15.

p53 in head and neck cancer: functional consequences and environmental implications of TP53 mutations.

Peltonen JK, Helppi HM, Pääkkö P, Turpeenniemi-Hujanen T, Vähäkangas KH.

Head Neck Oncol. 2010 Dec 15;2:36. doi: 10.1186/1758-3284-2-36.

16.

Zeb1 and twist are more commonly expressed in metastatic than primary lung tumours and show inverse associations with claudins.

Merikallio H, Kaarteenaho R, Pääkkö P, Lehtonen S, Hirvikoski P, Mäkitaro R, Harju T, Soini Y.

J Clin Pathol. 2011 Feb;64(2):136-40. doi: 10.1136/jcp.2010.086678. Epub 2010 Dec 2.

PMID:
21131312
17.

Variability in the precursor proteins of collagen I and III in different stages of COPD.

Harju T, Kinnula VL, Pääkkö P, Salmenkivi K, Risteli J, Kaarteenaho R.

Respir Res. 2010 Nov 30;11:165. doi: 10.1186/1465-9921-11-165.

18.

Impact of smoking on the expression of claudins in lung carcinoma.

Merikallio H, Kaarteenaho R, Pääkkö P, Lehtonen S, Hirvikoski P, Mäkitaro R, Harju T, Soini Y.

Eur J Cancer. 2011 Mar;47(4):620-30. doi: 10.1016/j.ejca.2010.10.017. Epub 2010 Nov 22.

PMID:
21106366
19.

Variable expression of tenascin-C, osteopontin and fibronectin in inflammatory myofibroblastic tumour of the lung.

Kaarteenaho R, Sormunen R, Pääkkö P.

APMIS. 2010 Feb;118(2):91-100. doi: 10.1111/j.1600-0463.2009.02566.x.

PMID:
20132172
20.

Immunohistochemical study of matrix metalloproteinase 9 and tissue inhibitor of matrix metalloproteinase 1 in benign and malignant breast tissue--strong expression in intraductal carcinomas of the breast.

Rahko E, Kauppila S, Pääkkö P, Blanco G, Apaja-Sarkkinen M, Talvensaari-Mattila A, Turpeenniemi-Hujanen T, Jukkola A.

Tumour Biol. 2009;30(5-6):257-64. doi: 10.1159/000253662. Epub 2009 Oct 31.

PMID:
19887890
21.

Ultrastructural features of lung fibroblast differentiation into myofibroblasts.

Kaarteenaho-Wiik R, Paakko P, Sormunen R.

Ultrastruct Pathol. 2009 Jan-Feb;33(1):6-15. doi: 10.1080/01913120802608430.

PMID:
19191196
22.

Matrix metalloproteinase-9 (MMP-9) immunoreactive protein in urinary bladder cancer: a marker of favorable prognosis.

Vasala K, Pääkko P, Turpeenniemi-Hujanen T.

Anticancer Res. 2008 May-Jun;28(3B):1757-61.

23.

Does the oxidative stress in chronic obstructive pulmonary disease cause thioredoxin/peroxiredoxin oxidation?

Lehtonen ST, Ohlmeier S, Kaarteenaho-Wiik R, Harju T, Pääkkö P, Soini Y, Kinnula VL.

Antioxid Redox Signal. 2008 Apr;10(4):813-9. doi: 10.1089/ars.2007.1952.

PMID:
18179358
24.

High serum TIMP-1 correlates with poor prognosis in breast carcinoma - a validation study.

Kuvaja P, Würtz SØ, Talvensaari-Mattila A, Brünner N, Pääkkö P, Turpeenniemi-Hujanen T.

Cancer Biomark. 2007;3(6):293-300.

PMID:
18048967
25.

Differential expression of adhesion molecules in lung tumours.

Sormunen R, Pääkkö P, Kaarteenaho-Wiik R, Soini Y.

Histopathology. 2007 Jan;50(2):282-4. No abstract available.

PMID:
17222260
26.

Poly-L/D-lactide (PLDLA) 96/4 fibrous implants: histological evaluation in the subcutis of experimental design.

Länsman S, Pääkkö P, Ryhänen J, Kellomäki M, Waris E, Törmälä P, Waris T, Ashammakhi N.

J Craniofac Surg. 2006 Nov;17(6):1121-8.

PMID:
17119416
27.

COX-2 is widely expressed in metaplastic epithelium in pulmonary fibrous disorders.

Lappi-Blanco E, Kaarteenaho-Wiik R, Maasilta PK, Anttila S, Pääkkö P, Wolff HJ.

Am J Clin Pathol. 2006 Nov;126(5):717-24.

PMID:
17050069
28.

Extracellular matrix proteins and myofibroblasts in granulomas of sarcoidosis, atypical mycobacteriosis, and tuberculosis of the lung.

Kaarteenaho-Wiik R, Sademies O, Pääkkö P, Risteli J, Soini Y.

Hum Pathol. 2007 Jan;38(1):147-53. Epub 2006 Sep 25.

PMID:
16996565
29.

Low serum level of pro-matrix metalloproteinase 2 correlates with aggressive behavior in breast carcinoma.

Kuvaja P, Talvensaari-Mattila A, Pääkkö P, Turpeenniemi-Hujanen T.

Hum Pathol. 2006 Oct;37(10):1316-23. Epub 2006 Jul 26.

PMID:
16949931
30.

Extracellular superoxide dismutase has a highly specific localization in idiopathic pulmonary fibrosis/usual interstitial pneumonia.

Kinnula VL, Hodgson UA, Lakari EK, Tan RJ, Sormunen RT, Soini YM, Kakko SJ, Laitinen TH, Oury TD, Pääkkö PK.

Histopathology. 2006 Jul;49(1):66-74.

31.

Relationship between histopathological features and the course of idiopathic pulmonary fibrosis/usual interstitial pneumonia.

Tiitto L, Bloigu R, Heiskanen U, Pääkkö P, Kinnula VL, Kaarteenaho-Wiik R.

Thorax. 2006 Dec;61(12):1091-5. Epub 2006 Jun 12.

32.

Localization of precursor proteins and mRNA of type I and III collagens in usual interstitial pneumonia and sarcoidosis.

Kaarteenaho-Wiik R, Lammi L, Lakari E, Kinnula VL, Risteli J, Ryhänen L, Pääkkö P.

J Mol Histol. 2005 Sep;36(6-7):437-46. Epub 2006 Mar 7.

PMID:
16521042
33.

Claudins in differential diagnosis between mesothelioma and metastatic adenocarcinoma of the pleura.

Soini Y, Kinnula V, Kahlos K, Pääkkö P.

J Clin Pathol. 2006 Mar;59(3):250-4.

35.

Nitric oxide synthases are associated with bronchial dysplasia.

Puhakka AR, Harju TH, Pääkkö PK, Soini YM, Kinnula VL.

Lung Cancer. 2006 Mar;51(3):275-82. Epub 2006 Jan 18.

PMID:
16420964
36.

Adrenomedullin gene transfer induces neointimal apoptosis and inhibits neointimal hyperplasia in injured rat artery.

Rauma-Pinola T, Pääkkö P, Ilves M, Serpi R, Romppanen H, Vuolteenaho O, Ruskoaho H, Hautala T.

J Gene Med. 2006 Apr;8(4):452-8.

PMID:
16389603
37.

Histologic analysis of bioabsorbable scleral buckling implants: an experimental study on rabbits.

Länsman S, Pääkkö P, Ryhänen J, Hirvelä H, Kellomäki M, Ellä V, Törmälä P, Waris T, Ashammakhi NA.

Retina. 2005 Dec;25(8):1032-8.

PMID:
16340534
38.

Thoracoscopic lung biopsy is a safe procedure in diagnosing usual interstitial pneumonia.

Tiitto L, Heiskanen U, Bloigu R, Pääkkö P, Kinnula V, Kaarteenaho-Wiik R.

Chest. 2005 Oct;128(4):2375-80.

PMID:
16236897
39.
40.

Activation and relocalization of caspase 3 during the apoptotic cascade of human mesothelioma cells.

Soini Y, Kahlos K, Sormunen R, Säily M, Mäntymaa P, Koistinen P, Pääkkö P, Kinnula V.

APMIS. 2005 Jun;113(6):426-35.

PMID:
15996160
41.

Tissue MMP-2 and MMP-9 [corrected] are better prognostic factors than serum MMP-2/TIMP-2--complex or TIMP-1 [corrected] in stage [corrected] I-III lung carcinoma.

Hoikkala S, Pääkkö P, Soini Y, Mäkitaro R, Kinnula V, Turpeenniemi-Hujanen T.

Cancer Lett. 2006 May 8;236(1):125-32. Epub 2005 Jun 27. Erratum in: Cancer Lett. 2007 Mar 18;247(2):359.

PMID:
15982804
42.
43.

Serum matrix metalloproteinase-9 in head and neck squamous cell carcinoma is a prognostic marker.

Ruokolainen H, Pääkkö P, Turpeenniemi-Hujanen T.

Int J Cancer. 2005 Sep 1;116(3):422-7.

44.

Manganese superoxide dismutase is increased in the airways of smokers' lungs.

Harju T, Kaarteenaho-Wiik R, Sirviö R, Pääkkö P, Crapo JD, Oury TD, Soini Y, Kinnula VL.

Eur Respir J. 2004 Nov;24(5):765-71.

45.

Differential expression of superoxide dismutases in lung cancer.

Svensk AM, Soini Y, Pääkkö P, Hiravikoski P, Kinnula VL.

Am J Clin Pathol. 2004 Sep;122(3):395-404.

PMID:
15362370
46.

Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo.

Peltoniemi M, Kaarteenaho-Wiik R, Säily M, Sormunen R, Pääkkö P, Holmgren A, Soini Y, Kinnula VL.

Hum Pathol. 2004 Aug;35(8):1000-7.

PMID:
15297967
47.

Cell-specific regulation of gamma-glutamylcysteine synthetase in human interstitial lung diseases.

Tiitto LH, Peltoniemi MJ, Kaarteenaho-Wiik RL, Soini YM, Pääkkö PK, Sormunen RT, Kinnula VL.

Hum Pathol. 2004 Jul;35(7):832-9.

PMID:
15257546
48.

Peroxiredoxins, a novel protein family in lung cancer.

Lehtonen ST, Svensk AM, Soini Y, Pääkkö P, Hirvikoski P, Kang SW, Säily M, Kinnula VL.

Int J Cancer. 2004 Sep 10;111(4):514-21.

49.

Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung.

Kinnula VL, Pääkkö P, Soini Y.

FEBS Lett. 2004 Jul 2;569(1-3):1-6. Review.

50.

Expression of matrix metalloproteinase-9 in head and neck squamous cell carcinoma: a potential marker for prognosis.

Ruokolainen H, Pääkkö P, Turpeenniemi-Hujanen T.

Clin Cancer Res. 2004 May 1;10(9):3110-6.

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