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Items: 37

1.

Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment.

Geraghty AC, Gibson EM, Ghanem RA, Greene JJ, Ocampo A, Goldstein AK, Ni L, Yang T, Marton RM, Paşca SP, Greenberg ME, Longo FM, Monje M.

Neuron. 2019 Jul 17;103(2):250-265.e8. doi: 10.1016/j.neuron.2019.04.032. Epub 2019 May 20.

PMID:
31122677
2.

Human 3D cellular model of hypoxic brain injury of prematurity.

Pașca AM, Park JY, Shin HW, Qi Q, Revah O, Krasnoff R, O'Hara R, Willsey AJ, Palmer TD, Pașca SP.

Nat Med. 2019 May;25(5):784-791. doi: 10.1038/s41591-019-0436-0. Epub 2019 May 6.

PMID:
31061540
3.

Cell diversity in the human cerebral cortex: from the embryo to brain organoids.

Arlotta P, Paşca SP.

Curr Opin Neurobiol. 2019 Jun;56:194-198. doi: 10.1016/j.conb.2019.03.001. Epub 2019 Apr 30. Review.

PMID:
31051421
4.

Polarizing brain organoids.

Miura Y, Pașca SP.

Nat Biotechnol. 2019 Apr;37(4):377-378. doi: 10.1038/s41587-019-0084-4. No abstract available.

PMID:
30936565
5.

Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures.

Marton RM, Miura Y, Sloan SA, Li Q, Revah O, Levy RJ, Huguenard JR, Pașca SP.

Nat Neurosci. 2019 Mar;22(3):484-491. doi: 10.1038/s41593-018-0316-9. Epub 2019 Jan 28.

PMID:
30692691
6.

Assembling human brain organoids.

Paşca SP.

Science. 2019 Jan 11;363(6423):126-127. doi: 10.1126/science.aau5729. No abstract available.

PMID:
30630918
7.

Reliability of human cortical organoid generation.

Yoon SJ, Elahi LS, Pașca AM, Marton RM, Gordon A, Revah O, Miura Y, Walczak EM, Holdgate GM, Fan HC, Huguenard JR, Geschwind DH, Pașca SP.

Nat Methods. 2019 Jan;16(1):75-78. doi: 10.1038/s41592-018-0255-0. Epub 2018 Dec 20.

8.

Absent forebrain replaced by embryonic stem cells.

Andersen J, Pașca SP.

Nature. 2018 Nov;563(7729):44-45. doi: 10.1038/d41586-018-06933-w. No abstract available.

PMID:
30375499
9.

Building Models of Brain Disorders with Three-Dimensional Organoids.

Amin ND, Paşca SP.

Neuron. 2018 Oct 24;100(2):389-405. doi: 10.1016/j.neuron.2018.10.007. Review.

PMID:
30359604
10.

Generation and assembly of human brain region-specific three-dimensional cultures.

Sloan SA, Andersen J, Pașca AM, Birey F, Pașca SP.

Nat Protoc. 2018 Sep;13(9):2062-2085. doi: 10.1038/s41596-018-0032-7.

11.

The ethics of experimenting with human brain tissue.

Farahany NA, Greely HT, Hyman S, Koch C, Grady C, Pașca SP, Sestan N, Arlotta P, Bernat JL, Ting J, Lunshof JE, Iyer EPR, Hyun I, Capestany BH, Church GM, Huang H, Song H.

Nature. 2018 Apr;556(7702):429-432. doi: 10.1038/d41586-018-04813-x. No abstract available.

12.

Building three-dimensional human brain organoids.

Paşca SP.

Nat Neurosci. 2018 Mar 28. doi: 10.1038/s41593-018-0107-3. [Epub ahead of print] No abstract available.

PMID:
29593345
13.

A human cellular model of amyotrophic lateral sclerosis.

Marton RM, Paşca SP.

Nat Med. 2018 Mar 6;24(3):256-257. doi: 10.1038/nm.4509. No abstract available.

PMID:
29509753
14.

The rise of three-dimensional human brain cultures.

Pașca SP.

Nature. 2018 Jan 24;553(7689):437-445. doi: 10.1038/nature25032. Review.

PMID:
29364288
15.

The Zika threat to the periphery.

Khan TA, Paşca SP.

Nat Neurosci. 2017 Aug 29;20(9):1191-1192. doi: 10.1038/nn.4633. No abstract available.

PMID:
28849792
16.

Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells.

Sloan SA, Darmanis S, Huber N, Khan TA, Birey F, Caneda C, Reimer R, Quake SR, Barres BA, Paşca SP.

Neuron. 2017 Aug 16;95(4):779-790.e6. doi: 10.1016/j.neuron.2017.07.035.

17.

MicroRNA-9 Couples Brain Neurogenesis and Angiogenesis.

Madelaine R, Sloan SA, Huber N, Notwell JH, Leung LC, Skariah G, Halluin C, Paşca SP, Bejerano G, Krasnow MA, Barres BA, Mourrain P.

Cell Rep. 2017 Aug 15;20(7):1533-1542. doi: 10.1016/j.celrep.2017.07.051.

18.

Assembly of functionally integrated human forebrain spheroids.

Birey F, Andersen J, Makinson CD, Islam S, Wei W, Huber N, Fan HC, Metzler KRC, Panagiotakos G, Thom N, O'Rourke NA, Steinmetz LM, Bernstein JA, Hallmayer J, Huguenard JR, Paşca SP.

Nature. 2017 May 4;545(7652):54-59. doi: 10.1038/nature22330. Epub 2017 Apr 26.

19.

Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring.

Cao Y, Hjort M, Chen H, Birey F, Leal-Ortiz SA, Han CM, Santiago JG, Paşca SP, Wu JC, Melosh NA.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1866-E1874. doi: 10.1073/pnas.1615375114. Epub 2017 Feb 21.

20.

Neural Differentiation in the Third Dimension: Generating a Human Midbrain.

Marton RM, Paşca SP.

Cell Stem Cell. 2016 Aug 4;19(2):145-146. doi: 10.1016/j.stem.2016.07.017.

21.

A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients.

Sun Y, Paşca SP, Portmann T, Goold C, Worringer KA, Guan W, Chan KC, Gai H, Vogt D, Chen YJ, Mao R, Chan K, Rubenstein JL, Madison DV, Hallmayer J, Froehlich-Santino WM, Bernstein JA, Dolmetsch RE.

Elife. 2016 Jul 26;5. pii: e13073. doi: 10.7554/eLife.13073.

22.

Personalized Human Cortical Spheroids.

Paşca SP.

Am J Psychiatry. 2016 Apr 1;173(4):332-3. doi: 10.1176/appi.ajp.2016.16020133. No abstract available.

PMID:
27035533
23.

Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain.

Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Chan KY, Banerjee A, Wu WL, Yang B, Huber N, Pasca SP, Gradinaru V.

Nat Biotechnol. 2016 Feb;34(2):204-9. doi: 10.1038/nbt.3440. Epub 2016 Feb 1.

24.

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture.

Paşca AM, Sloan SA, Clarke LE, Tian Y, Makinson CD, Huber N, Kim CH, Park JY, O'Rourke NA, Nguyen KD, Smith SJ, Huguenard JR, Geschwind DH, Barres BA, Paşca SP.

Nat Methods. 2015 Jul;12(7):671-8. doi: 10.1038/nmeth.3415. Epub 2015 May 25.

25.

Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome.

Tian Y, Voineagu I, Paşca SP, Won H, Chandran V, Horvath S, Dolmetsch RE, Geschwind DH.

Genome Med. 2014 Oct 10;6(10):75. doi: 10.1186/s13073-014-0075-5. eCollection 2014.

26.

Generating human neurons in vitro and using them to understand neuropsychiatric disease.

Paşca SP, Panagiotakos G, Dolmetsch RE.

Annu Rev Neurosci. 2014;37:479-501. doi: 10.1146/annurev-neuro-062012-170328. Epub 2014 Jun 23. Review.

PMID:
25002278
27.

Motor abnormalities as a putative endophenotype for Autism Spectrum Disorders.

Esposito G, Paşca SP.

Front Integr Neurosci. 2013 Jun 11;7:43. doi: 10.3389/fnint.2013.00043. eCollection 2013.

28.

A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT.

Gomez-Ospina N, Panagiotakos G, Portmann T, Pasca SP, Rabah D, Budzillo A, Kinet JP, Dolmetsch RE.

PLoS One. 2013 Apr 16;8(4):e60526. doi: 10.1371/journal.pone.0060526. Print 2013.

29.

Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons.

Krey JF, Paşca SP, Shcheglovitov A, Yazawa M, Schwemberger R, Rasmusson R, Dolmetsch RE.

Nat Neurosci. 2013 Feb;16(2):201-9. doi: 10.1038/nn.3307. Epub 2013 Jan 13.

30.

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome.

Paşca SP, Portmann T, Voineagu I, Yazawa M, Shcheglovitov A, Paşca AM, Cord B, Palmer TD, Chikahisa S, Nishino S, Bernstein JA, Hallmayer J, Geschwind DH, Dolmetsch RE.

Nat Med. 2011 Nov 27;17(12):1657-62. doi: 10.1038/nm.2576.

31.

Surround modulation of neuronal responses in V1 is as stable over time as responses to direct stimulation of receptive fields.

Paşca SP, Singer W, Nikolić D.

Cortex. 2010 Oct;46(9):1199-203. doi: 10.1016/j.cortex.2010.05.003. Epub 2010 May 24.

PMID:
20557882
32.

One carbon metabolism disturbances and the C677T MTHFR gene polymorphism in children with autism spectrum disorders.

Paşca SP, Dronca E, Kaucsár T, Craciun EC, Endreffy E, Ferencz BK, Iftene F, Benga I, Cornean R, Banerjee R, Dronca M.

J Cell Mol Med. 2009 Oct;13(10):4229-38. doi: 10.1111/j.1582-4934.2008.00463.x.

33.

Paraoxonase 1 activities and polymorphisms in autism spectrum disorders.

Paşca SP, Dronca E, Nemeş B, Kaucsár T, Endreffy E, Iftene F, Benga I, Cornean R, Dronca M.

J Cell Mol Med. 2010 Mar;14(3):600-7. doi: 10.1111/j.1582-4934.2008.00414.x. Epub 2009 Jun 28.

34.

Serum paraoxonase 1 activities and homocysteinemia in hemodialysis patients.

Dronca M, Paşca SP, Nemeş B, Vlase L, Vladutiu D.

Clin Chem Lab Med. 2008;46(6):880-1. doi: 10.1515/CCLM.2008.164. No abstract available.

PMID:
18601616
35.

Vomiting is not an adaption for glaucoma (and Darwinian medicine is difficult).

Paşca SP, Nesse RM.

Med Hypotheses. 2008 Sep;71(3):472-3. doi: 10.1016/j.mehy.2008.04.009. Epub 2008 May 29. No abstract available.

36.

Behavioral effects of corpus callosum transection and environmental enrichment in adult rats.

Miu AC, Heilman RM, Paşca SP, Stefan CA, Spânu F, Vasiu R, Olteanu AI, Miclea M.

Behav Brain Res. 2006 Sep 15;172(1):135-44. Epub 2006 Jun 9.

PMID:
16764947
37.

High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism.

Paşca SP, Nemeş B, Vlase L, Gagyi CE, Dronca E, Miu AC, Dronca M.

Life Sci. 2006 Apr 4;78(19):2244-8. Epub 2005 Nov 17.

PMID:
16297937

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