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Items: 22


Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins.

Gingras AR, Puzon-McLaughlin W, Bobkov AA, Ginsberg MH.

Structure. 2016 Dec 6;24(12):2152-2162. doi: 10.1016/j.str.2016.10.001. Epub 2016 Nov 10.


The structure of the ternary complex of Krev interaction trapped 1 (KRIT1) bound to both the Rap1 GTPase and the heart of glass (HEG1) cytoplasmic tail.

Gingras AR, Puzon-McLaughlin W, Ginsberg MH.

J Biol Chem. 2013 Aug 16;288(33):23639-49. doi: 10.1074/jbc.M113.462911. Epub 2013 Jun 27.


RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences.

Lee HS, Lim CJ, Puzon-McLaughlin W, Shattil SJ, Ginsberg MH.

J Biol Chem. 2009 Feb 20;284(8):5119-27. doi: 10.1074/jbc.M807117200. Epub 2008 Dec 19.


Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

Han J, Lim CJ, Watanabe N, Soriani A, Ratnikov B, Calderwood DA, Puzon-McLaughlin W, Lafuente EM, Boussiotis VA, Shattil SJ, Ginsberg MH.

Curr Biol. 2006 Sep 19;16(18):1796-806.


Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit.

Kamata T, Ambo H, Puzon-McLaughlin W, Tieu KK, Handa M, Ikeda Y, Takada Y.

Biochem J. 2004 Mar 15;378(Pt 3):1079-82.


Differential regulation of cellular adhesion and migration by recombinant laminin-5 forms with partial deletion or mutation within the G3 domain of alpha3 chain.

Kariya Y, Tsubota Y, Hirosaki T, Mizushima H, Puzon-McLaughlin W, Takada Y, Miyazaki K.

J Cell Biochem. 2003 Feb 15;88(3):506-20.


A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29).

Lévesque JP, Takada Y, Puzon-McLaughlin W, Simmons PJ.

Hybrid Hybridomics. 2002 Aug;21(4):253-60.


Differential regulation of Rho GTPases by beta1 and beta3 integrins: the role of an extracellular domain of integrin in intracellular signaling.

Miao H, Li S, Hu YL, Yuan S, Zhao Y, Chen BP, Puzon-McLaughlin W, Tarui T, Shyy JY, Takada Y, Usami S, Chien S.

J Cell Sci. 2002 May 15;115(Pt 10):2199-206.


Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions.

Eto K, Huet C, Tarui T, Kupriyanov S, Liu HZ, Puzon-McLaughlin W, Zhang XP, Sheppard D, Engvall E, Takada Y.

J Biol Chem. 2002 May 17;277(20):17804-10. Epub 2002 Mar 6.


The role of the CPNKEKEC sequence in the beta(2) subunit I domain in regulation of integrin alpha(L)beta(2) (LFA-1).

Kamata T, Tieu KK, Tarui T, Puzon-McLaughlin W, Hogg N, Takada Y.

J Immunol. 2002 Mar 1;168(5):2296-301.


RGD-independent binding of integrin alpha9beta1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction.

Eto K, Puzon-McLaughlin W, Sheppard D, Sehara-Fujisawa A, Zhang XP, Takada Y.

J Biol Chem. 2000 Nov 10;275(45):34922-30.


Alpha 3 beta 1 adhesion to laminin-5 and invasin: critical and differential role of integrin residues clustered at the boundary between alpha 3 N-terminal repeats 2 and 3.

Zhang XP, Puzon-McLaughlin W, Irie A, Kovach N, Prokopishyn NL, Laferté S, Takeuchi K, Tsuji T, Takada Y.

Biochemistry. 1999 Oct 26;38(43):14424-31.


Integrin alpha3beta1 expressed by human colon cancer cells is a major carrier of oncodevelopmental carbohydrate epitopes.

Prokopishyn NL, Puzon-McLaughlin W, Takada Y, Laferté S.

J Cell Biochem. 1999 Feb 1;72(2):189-209.


Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3.

Zhang XP, Kamata T, Yokoyama K, Puzon-McLaughlin W, Takada Y.

J Biol Chem. 1998 Mar 27;273(13):7345-50.


Structural basis of integrin-mediated signal transduction.

Takada Y, Kamata T, Irie A, Puzon-McLaughlin W, Zhang XP.

Matrix Biol. 1997 Oct;16(4):143-51. Review.


Changing ligand specificities of alphavbeta1 and alphavbeta3 integrins by swapping a short diverse sequence of the beta subunit.

Takagi J, Kamata T, Meredith J, Puzon-McLaughlin W, Takada Y.

J Biol Chem. 1997 Aug 8;272(32):19794-800.


Critical residues for ligand binding in an I domain-like structure of the integrin beta1 subunit.

Puzon-McLaughlin W, Takada Y.

J Biol Chem. 1996 Aug 23;271(34):20438-43.


Regulation of conformation and ligand binding function of integrin alpha5beta1 by the beta1 cytoplasmic domain.

Puzon-McLaughlin W, Yednock TA, Takada Y.

J Biol Chem. 1996 Jul 12;271(28):16580-5.


Induction of experimental bone metastasis in mice by transfection of integrin alpha 4 beta 1 into tumor cells.

Matsuura N, Puzon-McLaughlin W, Irie A, Morikawa Y, Kakudo K, Takada Y.

Am J Pathol. 1996 Jan;148(1):55-61.

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