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Items: 1 to 50 of 80

1.

Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS.

Ni Z, Sousa BC, Colombo S, Afonso CB, Melo T, Pitt AR, Spickett CM, Domingues P, Domingues MR, Fedorova M, Criscuolo A.

Free Radic Biol Med. 2019 Jun 15. pii: S0891-5849(19)30347-8. doi: 10.1016/j.freeradbiomed.2019.06.013. [Epub ahead of print]

2.

Short-chain lipid peroxidation products form covalent adducts with pyruvate kinase and inhibit its activity in vitro and in breast cancer cells.

Sousa BC, Ahmed T, Dann WL, Ashman J, Guy A, Durand T, Pitt AR, Spickett CM.

Free Radic Biol Med. 2019 Jun 5. pii: S0891-5849(19)30341-7. doi: 10.1016/j.freeradbiomed.2019.05.028. [Epub ahead of print]

3.

Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies.

Campos-Pinto I, Méndez L, Schouten J, Wilkins J, Fedorova M, Pitt AR, Davis P, Spickett CM.

Free Radic Biol Med. 2019 May 7. pii: S0891-5849(19)30354-5. doi: 10.1016/j.freeradbiomed.2019.05.008. [Epub ahead of print]

4.

Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration.

Rossin D, Dias IHK, Solej M, Milic I, Pitt AR, Iaia N, Scoppapietra L, Devitt A, Nano M, Degiuli M, Volante M, Caccia C, Leoni V, Griffiths HR, Spickett CM, Poli G, Biasi F.

Free Radic Biol Med. 2019 May 20;136:35-44. doi: 10.1016/j.freeradbiomed.2019.03.020. Epub 2019 Mar 23.

PMID:
30910555
5.

Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein.

Teo ACK, Lee SC, Pollock NL, Stroud Z, Hall S, Thakker A, Pitt AR, Dafforn TR, Spickett CM, Roper DI.

Sci Rep. 2019 Feb 12;9(1):1813. doi: 10.1038/s41598-018-37962-0.

6.

A mass spectrometry approach for the identification and localization of small aldehyde modifications of proteins.

Afonso CB, Sousa BC, Pitt AR, Spickett CM.

Arch Biochem Biophys. 2018 May 15;646:38-45. doi: 10.1016/j.abb.2018.03.026. Epub 2018 Mar 23.

PMID:
29580947
7.

A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells.

Knight AR, Taylor EL, Lukaszewski R, Jensen KT, Jones HE, Carré JE, Isupov MN, Littlechild JA, Bailey SJ, Brewer E, McDonald TJ, Pitt AR, Spickett CM, Winyard PG.

Free Radic Biol Med. 2018 May 20;120:246-254. doi: 10.1016/j.freeradbiomed.2018.03.026. Epub 2018 Mar 17.

PMID:
29555590
8.

The effect of HOCl-induced modifications on phosphatase and tensin homologue (PTEN) structure and function.

Verrastro I, Tveen-Jensen K, Spickett CM, Pitt AR.

Free Radic Res. 2018 Feb;52(2):232-247. doi: 10.1080/10715762.2018.1424333. Epub 2018 Jan 22.

PMID:
29298524
9.

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A.

Redox Biol. 2018 Apr;14:694-696. doi: 10.1016/j.redox.2017.10.001. Epub 2017 Oct 26. No abstract available.

10.

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A.

Redox Biol. 2017 Oct;13:94-162. doi: 10.1016/j.redox.2017.05.007. Epub 2017 May 18. Review. Erratum in: Redox Biol. 2018 Apr;14 :694-696.

11.

Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds.

Sousa BC, Pitt AR, Spickett CM.

Free Radic Biol Med. 2017 Oct;111:294-308. doi: 10.1016/j.freeradbiomed.2017.02.003. Epub 2017 Feb 10. Review.

PMID:
28192230
12.

Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins.

Verrastro I, Tveen-Jensen K, Woscholski R, Spickett CM, Pitt AR.

Free Radic Biol Med. 2016 Jan;90:24-34. doi: 10.1016/j.freeradbiomed.2015.11.004. Epub 2015 Nov 10.

13.

Targeted mass spectrometry methods for detecting oxidative post-translational modifications.

Tveen-Jensen K, Reis A, Spickett CM, Pitt AR.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S52-3. doi: 10.1016/j.freeradbiomed.2014.10.825. Epub 2014 Dec 10.

PMID:
26461406
14.

Detection and quantification of protein oxidation in sarcopenic models: a mass spectrometry study.

Pasha S, Tveen Jensen K, Pitt AR, Spickett CM.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S44. doi: 10.1016/j.freeradbiomed.2014.10.800. Epub 2014 Dec 10.

PMID:
26461380
15.

Interfacing low-energy SAW nebulization with Liquid Chromatography-Mass Spectrometry for the analysis of biological samples.

Tveen-Jensen K, Gesellchen F, Wilson R, Spickett CM, Cooper JM, Pitt AR.

Sci Rep. 2015 May 15;5:9736. doi: 10.1038/srep09736.

16.

Mass spectrometry-based methods for identifying oxidized proteins in disease: advances and challenges.

Verrastro I, Pasha S, Jensen KT, Pitt AR, Spickett CM.

Biomolecules. 2015 Apr 14;5(2):378-411. doi: 10.3390/biom5020378. Review.

17.

Oxidative lipidomics coming of age: advances in analysis of oxidized phospholipids in physiology and pathology.

Spickett CM, Pitt AR.

Antioxid Redox Signal. 2015 Jun 20;22(18):1646-66. doi: 10.1089/ars.2014.6098. Epub 2015 Mar 26. Review.

18.

Top-down lipidomics of low density lipoprotein reveal altered lipid profiles in advanced chronic kidney disease.

Reis A, Rudnitskaya A, Chariyavilaskul P, Dhaun N, Melville V, Goddard J, Webb DJ, Pitt AR, Spickett CM.

J Lipid Res. 2015 Feb;56(2):413-22. doi: 10.1194/jlr.M055624. Epub 2014 Nov 25.

19.

Identification and relative quantification of tyrosine nitration in a model peptide using two-dimensional infrared spectroscopy.

Rezende Valim L, Davies JA, Tveen Jensen K, Guo R, Willison KR, Spickett CM, Pitt AR, Klug DR.

J Phys Chem B. 2014 Nov 13;118(45):12855-64. doi: 10.1021/jp509053q. Epub 2014 Nov 4.

20.

Magnetite-doped polydimethylsiloxane (PDMS) for phosphopeptide enrichment.

Sandison ME, Jensen KT, Gesellchen F, Cooper JM, Pitt AR.

Analyst. 2014 Oct 7;139(19):4974-81. doi: 10.1039/c4an00750f.

21.

Quantification of functionalised gold nanoparticle-targeted knockdown of gene expression in HeLa cells.

Jiwaji M, Sandison ME, Reboud J, Stevenson R, Daly R, Barkess G, Faulds K, Kolch W, Graham D, Girolami MA, Cooper JM, Pitt AR.

PLoS One. 2014 Jun 13;9(6):e99458. doi: 10.1371/journal.pone.0099458. eCollection 2014.

22.

HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells.

Robaszkiewicz A, Bartosz G, Pitt AR, Thakker A, Armstrong RA, Spickett CM, Soszyński M.

Arch Biochem Biophys. 2014 Apr 15;548:1-10. doi: 10.1016/j.abb.2014.02.013. Epub 2014 Mar 4.

PMID:
24607806
23.

Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH.

Maciel E, Neves BM, Santinha D, Reis A, Domingues P, Teresa Cruz M, Pitt AR, Spickett CM, Domingues MR.

Arch Biochem Biophys. 2014 Apr 15;548:38-45. doi: 10.1016/j.abb.2014.02.002. Epub 2014 Feb 20.

PMID:
24560783
24.

A comparison of five lipid extraction solvent systems for lipidomic studies of human LDL.

Reis A, Rudnitskaya A, Blackburn GJ, Mohd Fauzi N, Pitt AR, Spickett CM.

J Lipid Res. 2013 Jul;54(7):1812-24. doi: 10.1194/jlr.M034330. Epub 2013 May 13.

25.

Reporter ion-based mass spectrometry approaches for the detection of non-enzymatic protein modifications in biological samples.

Tveen-Jensen K, Reis A, Mouls L, Pitt AR, Spickett CM.

J Proteomics. 2013 Oct 30;92:71-9. doi: 10.1016/j.jprot.2013.03.033. Epub 2013 Apr 17.

PMID:
23603107
26.

Use of narrow mass-window, high-resolution extracted product ion chromatograms for the sensitive and selective identification of protein modifications.

Spickett CM, Reis A, Pitt AR.

Anal Chem. 2013 May 7;85(9):4621-7. doi: 10.1021/ac400131f. Epub 2013 Apr 23.

PMID:
23534669
27.

Unique reporter-based sensor platforms to monitor signalling in cells.

Jiwaji M, Daly R, Gibriel A, Barkess G, McLean P, Yang J, Pansare K, Cumming S, McLauchlan A, Kamola PJ, Bhutta MS, West AG, West KL, Kolch W, Girolami MA, Pitt AR.

PLoS One. 2012;7(11):e50521. doi: 10.1371/journal.pone.0050521. Epub 2012 Nov 29.

28.

Shaping acoustic fields as a toolset for microfluidic manipulations in diagnostic technologies.

Reboud J, Bourquin Y, Wilson R, Pall GS, Jiwaji M, Pitt AR, Graham A, Waters AP, Cooper JM.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15162-7. Epub 2012 Sep 4.

29.

Identification of oxidized phospholipids by electrospray ionization mass spectrometry and LC-MS using a QQLIT instrument.

Spickett CM, Reis A, Pitt AR.

Free Radic Biol Med. 2011 Dec 15;51(12):2133-49. doi: 10.1016/j.freeradbiomed.2011.09.003. Epub 2011 Sep 16.

PMID:
21983435
30.

Intracellular protein determination using droplet-based immunoassays.

Martino C, Zagnoni M, Sandison ME, Chanasakulniyom M, Pitt AR, Cooper JM.

Anal Chem. 2011 Jul 1;83(13):5361-8. doi: 10.1021/ac200876q. Epub 2011 Jun 7.

31.

Matrix-free mass spectrometric imaging using laser desorption ionisation Fourier transform ion cyclotron resonance mass spectrometry.

Goodwin RJ, Pitt AR, Harrison D, Weidt SK, Langridge-Smith PR, Barrett MP, Logan Mackay C.

Rapid Commun Mass Spectrom. 2011 Apr 15;25(7):969-72. doi: 10.1002/rcm.4939. Epub 2011 Mar 14.

32.

The Renilla luciferase gene as a reference gene for normalization of gene expression in transiently transfected cells.

Jiwaji M, Daly R, Pansare K, McLean P, Yang J, Kolch W, Pitt AR.

BMC Mol Biol. 2010 Dec 31;11:103. doi: 10.1186/1471-2199-11-103.

33.

Mass spectrometry imaging of pharmacological compounds in tissue sections.

Goodwin RJ, Pitt AR.

Bioanalysis. 2010 Feb;2(2):279-93. doi: 10.4155/bio.09.180. Review.

PMID:
21083310
34.

On-chip immunoprecipitation for protein purification.

Sandison ME, Cumming SA, Kolch W, Pitt AR.

Lab Chip. 2010 Oct 21;10(20):2805-13. doi: 10.1039/c005295g. Epub 2010 Aug 17.

PMID:
20714512
35.

A simple, sensitive and selective quantum-dot-based western blot method for the simultaneous detection of multiple targets from cell lysates.

Gilroy KL, Cumming SA, Pitt AR.

Anal Bioanal Chem. 2010 Sep;398(1):547-54. doi: 10.1007/s00216-010-3908-0. Epub 2010 Jun 27.

PMID:
20582696
36.

Effect of phosphatidylcholine chlorohydrins on human erythrocytes.

Robaszkiewicz A, Greig FH, Pitt AR, Spickett CM, Bartosz G, Soszyński M.

Chem Phys Lipids. 2010 Sep;163(7):639-47. doi: 10.1016/j.chemphyslip.2010.05.201. Epub 2010 Jun 1.

PMID:
20513376
37.

A solvent-free matrix application method for matrix-assisted laser desorption/ionization imaging of small molecules.

Goodwin RJ, Macintyre L, Watson DG, Scullion SP, Pitt AR.

Rapid Commun Mass Spectrom. 2010 Jun 15;24(11):1682-6. doi: 10.1002/rcm.4567.

PMID:
20486266
38.

Protein oxidation: role in signalling and detection by mass spectrometry.

Spickett CM, Pitt AR.

Amino Acids. 2012 Jan;42(1):5-21. doi: 10.1007/s00726-010-0585-4. Epub 2010 Apr 18. Review.

PMID:
20401673
40.

Stopping the clock on proteomic degradation by heat treatment at the point of tissue excision.

Goodwin RJ, Lang AM, Allingham H, Borén M, Pitt AR.

Proteomics. 2010 May;10(9):1751-61. doi: 10.1002/pmic.200900641.

PMID:
20217868
41.

Development of novel mass spectrometric methods for identifying HOCl-induced modifications to proteins.

Mouls L, Silajdzic E, Haroune N, Spickett CM, Pitt AR.

Proteomics. 2009 Mar;9(6):1617-31. doi: 10.1002/pmic.200800391.

PMID:
19253297
42.

Performance of five different electrospray ionisation sources in conjunction with rapid monolithic column liquid chromatography and fast MS/MS scanning.

Burgess KE, Lainson A, Imrie L, Fraser-Pitt D, Yaga R, Smith DG, Swart R, Pitt AR, Inglis NF.

Proteomics. 2009 Mar;9(6):1720-6. doi: 10.1002/pmic.200800200.

PMID:
19242933
43.

Rheology and stability of oil-in-water nanoemulsions stabilised by anionic surfactant and gelatin 2) addition of homologous series of sugar-based co-surfactants.

Howe AM, Pitt AR.

Adv Colloid Interface Sci. 2008 Dec 2;144(1-2):30-7. doi: 10.1016/j.cis.2008.08.004. Epub 2008 Aug 20.

PMID:
18842252
44.

Rheology and stability of oil-in-water nanoemulsions stabilised by anionic surfactant and gelatin 1) addition of nonionic, cationic and ethoxylated-cationic co-surfactants.

Howe AM, Pitt AR.

Adv Colloid Interface Sci. 2008 Dec 2;144(1-2):24-9. doi: 10.1016/j.cis.2008.08.003. Epub 2008 Aug 20.

PMID:
18834965
45.

Mass spectrometric analysis of HOCl- and free-radical-induced damage to lipids and proteins.

Pitt AR, Spickett CM.

Biochem Soc Trans. 2008 Oct;36(Pt 5):1077-82. doi: 10.1042/BST0361077. Review.

PMID:
18793192
46.

Protein and peptides in pictures: imaging with MALDI mass spectrometry.

Goodwin RJ, Pennington SR, Pitt AR.

Proteomics. 2008 Sep;8(18):3785-800. doi: 10.1002/pmic.200800320. Review.

PMID:
18712772
47.

Time-dependent evolution of tissue markers by MALDI-MS imaging.

Goodwin RJ, Dungworth JC, Cobb SR, Pitt AR.

Proteomics. 2008 Sep;8(18):3801-8. doi: 10.1002/pmic.200800201.

PMID:
18712770
48.

Characterisation of the plasma membrane subproteome of bloodstream form Trypanosoma brucei.

Bridges DJ, Pitt AR, Hanrahan O, Brennan K, Voorheis HP, Herzyk P, de Koning HP, Burchmore RJ.

Proteomics. 2008 Jan;8(1):83-99.

PMID:
18095354
49.

Urinary proteomic biomarkers in coronary artery disease.

Zimmerli LU, Schiffer E, Zürbig P, Good DM, Kellmann M, Mouls L, Pitt AR, Coon JJ, Schmieder RE, Peter KH, Mischak H, Kolch W, Delles C, Dominiczak AF.

Mol Cell Proteomics. 2008 Feb;7(2):290-8. Epub 2007 Oct 19.

50.

Incorporation of N-heterocyclic cations into proteins with a highly directed chemical modification.

McMillan N, Smith LV, de la Fuente JM, Parenty AD, Gadegaard N, Pitt AR, Thomson K, Mackenzie C, Kelly SM, Cronin L.

Chem Commun (Camb). 2007 Jul 7;(25):2581-3. Epub 2007 May 29.

PMID:
17579744

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