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Items: 30

1.

Identification of a nuclear localization signal and importin beta members mediating NUAK1 nuclear import inhibited by oxidative stress.

Palma M, Riffo EN, Suganuma T, Washburn MP, Workman JL, Pincheira R, Castro AF.

J Cell Biochem. 2019 May 15. doi: 10.1002/jcb.28890. [Epub ahead of print]

PMID:
31090959
2.

DISC1 promotes translation maintenance during sodium arsenite-induced oxidative stress.

Fuentes-Villalobos F, Farkas C, Riquelme-Barrios S, Armijo ME, Soto-Rifo R, Pincheira R, Castro AF.

Biochim Biophys Acta Gene Regul Mech. 2019 Jun;1862(6):657-669. doi: 10.1016/j.bbagrm.2019.05.001. Epub 2019 May 7.

PMID:
31075539
3.

Streamlined computational pipeline for genetic background characterization of genetically engineered mice based on next generation sequencing data.

Farkas C, Fuentes-Villalobos F, Rebolledo-Jaramillo B, Benavides F, Castro AF, Pincheira R.

BMC Genomics. 2019 Feb 12;20(1):131. doi: 10.1186/s12864-019-5504-9.

4.

A Trichostatin A (TSA)/Sp1-mediated mechanism for the regulation of SALL2 tumor suppressor in Jurkat T cells.

Hepp MI, Escobar D, Farkas C, Hermosilla VE, Álvarez C, Amigo R, Gutiérrez JL, Castro AF, Pincheira R.

Biochim Biophys Acta Gene Regul Mech. 2018 May 18. pii: S1874-9399(18)30028-2. doi: 10.1016/j.bbagrm.2018.05.002. [Epub ahead of print]

PMID:
29778644
5.

SALL2 represses cyclins D1 and E1 expression and restrains G1/S cell cycle transition and cancer-related phenotypes.

E Hermosilla V, Salgado G, Riffo E, Escobar D, Hepp MI, Farkas C, Galindo M, Morín V, García-Robles MA, Castro AF, Pincheira R.

Mol Oncol. 2018 Jun;12(7):1026-1046. doi: 10.1002/1878-0261.12308. Epub 2018 May 21.

6.

Developmental SALL2 transcription factor: a new player in cancer.

Hermosilla VE, Hepp MI, Escobar D, Farkas C, Riffo EN, Castro AF, Pincheira R.

Carcinogenesis. 2017 Jul 1;38(7):680-690. doi: 10.1093/carcin/bgx036.

PMID:
28430874
7.

Rapamycin requires AMPK activity and p27 expression for promoting autophagy-dependent Tsc2-null cell survival.

Campos T, Ziehe J, Fuentes-Villalobos F, Riquelme O, Peña D, Troncoso R, Lavandero S, Morin V, Pincheira R, Castro AF.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1200-7. doi: 10.1016/j.bbamcr.2016.03.009. Epub 2016 Mar 11.

8.

Rheb signaling and tumorigenesis: mTORC1 and new horizons.

Armijo ME, Campos T, Fuentes-Villalobos F, Palma ME, Pincheira R, Castro AF.

Int J Cancer. 2016 Apr 15;138(8):1815-23. doi: 10.1002/ijc.29707. Epub 2015 Aug 17. Review.

9.

Sall2 is required for proapoptotic Noxa expression and genotoxic stress-induced apoptosis by doxorubicin.

Escobar D, Hepp MI, Farkas C, Campos T, Sodir NM, Morales M, Álvarez CI, Swigart L, Evan GI, Gutiérrez JL, Nishinakamura R, Castro AF, Pincheira R.

Cell Death Dis. 2015 Jul 16;6:e1816. doi: 10.1038/cddis.2015.165.

10.

Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy.

Campos T, Ziehe J, Palma M, Escobar D, Tapia JC, Pincheira R, Castro AF.

Mol Carcinog. 2016 Feb;55(2):220-9. doi: 10.1002/mc.22272. Epub 2015 Jan 15.

PMID:
25594310
11.

Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress.

Farkas C, Martins CP, Escobar D, Hepp MI, Castro AF, Evan G, Gutiérrez JL, Warren R, Donner DB, Pincheira R.

PLoS One. 2013 Sep 6;8(9):e73817. doi: 10.1371/journal.pone.0073817. eCollection 2013. Erratum in: PLoS One.2014;9(8):e104307. doi: 10.1371/journal.pone.0104307.

12.

Consequences of interrupted Rheb-to-AMPK feedback signaling in tuberous sclerosis complex and cancer.

Lacher MD, Pincheira RJ, Castro AF.

Small GTPases. 2011 Jul;2(4):211-216. Epub 2011 Jul 1.

13.

M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells.

Castro AF, Campos T, Babcock JT, Armijo ME, Martínez-Conde A, Pincheira R, Quilliam LA.

J Cell Biochem. 2012 Apr;113(4):1253-64. doi: 10.1002/jcb.23458.

14.

Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis.

Lacher MD, Pincheira R, Zhu Z, Camoretti-Mercado B, Matli M, Warren RS, Castro AF.

Oncogene. 2010 Dec 16;29(50):6543-56. doi: 10.1038/onc.2010.393. Epub 2010 Sep 6.

PMID:
20818424
15.

Role of eIF3a in regulating cell cycle progression.

Dong Z, Liu Z, Cui P, Pincheira R, Yang Y, Liu J, Zhang JT.

Exp Cell Res. 2009 Jul 1;315(11):1889-94. doi: 10.1016/j.yexcr.2009.03.009. Epub 2009 Mar 24.

PMID:
19327350
16.

Sall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowth.

Pincheira R, Baerwald M, Dunbar JD, Donner DB.

EMBO J. 2009 Feb 4;28(3):261-73. doi: 10.1038/emboj.2008.274. Epub 2009 Jan 8.

17.

The Sall2 transcription factor is a novel p75NTR binding protein that promotes the development and function of neurons.

Pincheira R, Donner DB.

Ann N Y Acad Sci. 2008 Nov;1144:53-5. doi: 10.1196/annals.1418.026.

PMID:
19076363
18.
19.

Enhanced peritoneal ovarian tumor dissemination by tissue transglutaminase.

Satpathy M, Cao L, Pincheira R, Emerson R, Bigsby R, Nakshatri H, Matei D.

Cancer Res. 2007 Aug 1;67(15):7194-202.

20.

Akt regulates basal and induced processing of NF-kappaB2 (p100) to p52.

Gustin JA, Korgaonkar CK, Pincheira R, Li Q, Donner DB.

J Biol Chem. 2006 Jun 16;281(24):16473-81. Epub 2006 Apr 12.

21.

Role of eIF3 p170 in controlling synthesis of ribonucleotide reductase M2 and cell growth.

Dong Z, Liu LH, Han B, Pincheira R, Zhang JT.

Oncogene. 2004 May 6;23(21):3790-801.

PMID:
15094776
22.

Tumor necrosis factor activates CRE-binding protein through a p38 MAPK/MSK1 signaling pathway in endothelial cells.

Gustin JA, Pincheira R, Mayo LD, Ozes ON, Kessler KM, Baerwald MR, Korgaonkar CK, Donner DB.

Am J Physiol Cell Physiol. 2004 Mar;286(3):C547-55.

23.

Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation.

Gustin JA, Ozes ON, Akca H, Pincheira R, Mayo LD, Li Q, Guzman JR, Korgaonkar CK, Donner DB.

J Biol Chem. 2004 Jan 16;279(3):1615-20. Epub 2003 Oct 29.

24.
25.

Identification of a 170-kDa protein over-expressed in lung cancers.

Pincheira R, Chen Q, Zhang JT.

Br J Cancer. 2001 Jun 1;84(11):1520-7.

26.

Vascular endothelial cell growth factor activates CRE-binding protein by signaling through the KDR receptor tyrosine kinase.

Mayo LD, Kessler KM, Pincheira R, Warren RS, Donner DB.

J Biol Chem. 2001 Jul 6;276(27):25184-9. Epub 2001 May 2.

27.

Increased expression of c-rel, from the NF-kappaB/Rel family, in T cells from patients with systemic lupus erythematosus.

Burgos P, Metz C, Bull P, Pincheira R, Massardo L, Errázuriz C, Bono MR, Jacobelli S, González A.

J Rheumatol. 2000 Jan;27(1):116-27.

PMID:
10648027
28.

Dissection of drug-binding-induced conformational changes in P-glycoprotein.

Wang G, Pincheira R, Zhang JT.

Eur J Biochem. 1998 Jul 15;255(2):383-90.

29.

Clinical evaluation of the effect of calcium-channel blockers on verbal learning.

Cárdenas AM, Vizcarra J, Raffo M, Pincheira R, Inostroza O, García R.

Eur Neuropsychopharmacol. 1998 Aug;8(3):187-9.

PMID:
9716311
30.

Conformational changes of P-glycoprotein by nucleotide binding.

Wang G, Pincheira R, Zhang M, Zhang JT.

Biochem J. 1997 Dec 15;328 ( Pt 3):897-904.

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