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Items: 1 to 50 of 76

1.

Population Pharmacokinetics of Levofloxacin in Plasma and Bone of Patients Undergoing Hip or Knee Surgery.

Gergs U, Ihlefeld D, Clauss T, Weiss M, Pönicke K, Hofmann GO, Neumann J.

Clin Pharmacol Drug Dev. 2017 Dec 18. doi: 10.1002/cpdd.418. [Epub ahead of print]

PMID:
29251833
2.

Pharmacokinetics of ceftriaxone in plasma and bone of patients undergoing hip or knee surgery.

Gergs U, Clauss T, Ihlefeld D, Weiss M, Pönicke K, Hofmann GO, Neumann J.

J Pharm Pharmacol. 2014 Nov;66(11):1552-8. doi: 10.1111/jphp.12282. Epub 2014 Jun 19.

PMID:
24941934
3.

Human 5-HT₄receptor stimulation in atria of transgenic mice.

Gergs U, Böckler A, Ebelt H, Hauptmann S, Keller N, Otto V, Pönicke K, Schmitz W, Neumann J.

Naunyn Schmiedebergs Arch Pharmacol. 2013 May;386(5):357-67. doi: 10.1007/s00210-013-0831-x. Epub 2013 Jan 11.

PMID:
23307014
4.

On the presence of serotonin in mammalian cardiomyocytes.

Pönicke K, Gergs U, Buchwalow IB, Hauptmann S, Neumann J.

Mol Cell Biochem. 2012 Jun;365(1-2):301-12. doi: 10.1007/s11010-012-1270-6. Epub 2012 Feb 25.

PMID:
22367115
5.

Catecholamines are the key for explaining the biological relevance of insulin-melatonin antagonisms in type 1 and type 2 diabetes.

Peschke E, Hofmann K, Pönicke K, Wedekind D, Mühlbauer E.

J Pineal Res. 2012 May;52(4):389-96. doi: 10.1111/j.1600-079X.2011.00951.x. Epub 2011 Sep 19.

PMID:
21929683
6.

Inotropic effects of ivabradine in the mammalian heart.

Boldt A, Gergs U, Pönicke K, Simm A, Silber RE, Neumann J.

Pharmacology. 2010;86(5-6):249-58. doi: 10.1159/000320454. Epub 2010 Oct 21.

PMID:
20962545
7.

Cardiac overexpression of the human 5-HT4 receptor in mice.

Gergs U, Baumann M, Böckler A, Buchwalow IB, Ebelt H, Fabritz L, Hauptmann S, Keller N, Kirchhof P, Klöckner U, Pönicke K, Rueckschloss U, Schmitz W, Werner F, Neumann J.

Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H788-98. doi: 10.1152/ajpheart.00691.2009. Epub 2010 Jul 16.

8.

Pineal melatonin synthesis is decreased in type 2 diabetic Goto-Kakizaki rats.

Frese T, Bach AG, Mühlbauer E, Pönicke K, Brömme HJ, Welp A, Peschke E.

Life Sci. 2009 Sep 23;85(13-14):526-33. doi: 10.1016/j.lfs.2009.08.004. Epub 2009 Aug 18.

PMID:
19695268
9.

Increased melatonin synthesis in pineal glands of rats in streptozotocin induced type 1 diabetes.

Peschke E, Wolgast S, Bazwinsky I, Pönicke K, Muhlbauer E.

J Pineal Res. 2008 Nov;45(4):439-48. doi: 10.1111/j.1600-079X.2008.00612.x. Epub 2008 Jul 1.

PMID:
18624957
10.
11.

Beta 2-adrenoceptor-mediated intrinsic sympathomimetic activity of carteolol: an in vivo study.

Bruck H, Poller U, Lüssenhop H, Pönicke K, Temme T, Heusch G, Philipp T, Brodde OE.

Naunyn Schmiedebergs Arch Pharmacol. 2004 Nov;370(5):361-8. Epub 2004 Oct 23.

PMID:
15526107
12.

Effect of a beta 2-adrenoceptor stimulation on hyperglycemia-induced endothelial dysfunction.

Kabat A, Pönicke K, Salameh A, Mohr FW, Dhein S.

J Pharmacol Exp Ther. 2004 Feb;308(2):564-73. Epub 2003 Oct 30.

13.

Role of beta 1- and beta 2-adrenoceptors in hypertrophic and apoptotic effects of noradrenaline and adrenaline in adult rat ventricular cardiomyocytes.

Pönicke K, Heinroth-Hoffmann I, Brodde OE.

Naunyn Schmiedebergs Arch Pharmacol. 2003 Jun;367(6):592-9. Epub 2003 May 15.

PMID:
12750877
14.

Cardiac beta-adrenoceptor changes in monocrotaline-treated rats: differences between membrane preparations from whole ventricles and isolated ventricular cardiomyocytes.

Leineweber K, Seyfarth T, Abraham G, Gerbershagen HP, Heinroth-Hoffmann I, Pönicke K, Brodde OE.

J Cardiovasc Pharmacol. 2003 Mar;41(3):333-42.

PMID:
12605011
15.

Demonstration of functional M3-muscarinic receptors in ventricular cardiomyocytes of adult rats.

Pönicke K, Heinroth-Hoffmann I, Brodde OE.

Br J Pharmacol. 2003 Jan;138(1):156-60.

16.

Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure.

Leineweber K, Brandt K, Wludyka B, Beilfuss A, Pönicke K, Heinroth-Hoffmann I, Brodde OE.

Circ Res. 2002 Nov 29;91(11):1056-62.

17.

The ageing heart: influence of cellular and tissue ageing on total content and distribution of the variants of elongation factor-2.

Jäger D, Holtz J, Redpath NT, Müller SP, Pönicke K, Heinroth-Hoffmann I, Werdan K, Müller-Werdan U.

Mech Ageing Dev. 2002 Jul;123(10):1305-19.

PMID:
12297334
18.

The impact of insulin-like growth factor-1 on the pattern of cardiac elongation factor-2 variants in a model of overload.

Jäger D, Müller-Werdan U, Pönicke K, Holtz J, Werdan K, Müller SP.

Mol Cell Biochem. 2002 Jan;229(1-2):25-34.

PMID:
11936844
19.
20.

Cardiac beta-adrenoceptor desensitization due to increased beta-adrenoceptor kinase activity in chronic uremia.

Leineweber K, Heinroth-Hoffmann I, Pönicke K, Abraham G, Osten B, Brodde OE.

J Am Soc Nephrol. 2002 Jan;13(1):117-24.

21.

Noradrenaline-induced increase in protein synthesis in adult rat cardiomyocytes: involvement of only alpha1A-adrenoceptors.

Pönicke K, Schlüter KD, Heinroth-Hoffmann I, Seyfarth T, Goldberg M, Osten B, Piper HM, Brodde OE.

Naunyn Schmiedebergs Arch Pharmacol. 2001 Nov;364(5):444-53.

PMID:
11692228
22.

Impaired beta-adrenergic control of immune function in patients with chronic heart failure: reversal by beta1-blocker treatment.

Werner C, Werdan K, Pönicke K, Brodde OE.

Basic Res Cardiol. 2001 May-Jun;96(3):290-8.

PMID:
11403423
23.

ET-receptor function in relation to blood pressure in spontaneously hypertensive and aortic-banded rats.

Becker K, Heinroth-Hoffmann I, Pönicke K, Osten B, Brodde OE.

Naunyn Schmiedebergs Arch Pharmacol. 2001 Apr;363(4):439-47.

PMID:
11330338
24.

Inositolphosphate formation in thoracic and abdominal rat aorta following Gq/11-coupled receptor stimulation.

Dhein S, Giessler C, Becker K, Pönicke K, Brodde OE.

Naunyn Schmiedebergs Arch Pharmacol. 2001 Mar;363(3):322-9.

PMID:
11284447
25.

Beta-adrenoceptor stimulation attenuates the hypertrophic effect of alpha-adrenoceptor stimulation in adult rat ventricular cardiomyocytes.

Schäfer M, Pönicke K, Heinroth-Hoffmann I, Brodde OE, Piper HM, Schlüter KD.

J Am Coll Cardiol. 2001 Jan;37(1):300-7.

26.

The cardiac beta-adrenoceptor-G-protein(s)-adenylyl cyclase system in monocrotaline-treated rats.

Seyfarth T, Gerbershagen HP, Giessler C, Leineweber K, Heinroth-Hoffmann I, Pönicke K, Brodde OE.

J Mol Cell Cardiol. 2000 Dec;32(12):2315-26.

PMID:
11113007
27.

Heterogeneity of cardiac rat and human elongation factor 2.

Jäger D, Seliger C, Redpath NT, Friedrich I, Silber RE, Pönicke K, Werdan K, Müller-Werdan U.

Electrophoresis. 2000 Jul;21(13):2729-36.

PMID:
10949152
28.

FP-receptor mediated trophic effects of prostanoids in rat ventricular cardiomyocytes.

Pönicke K, Giessler C, Grapow M, Heinroth-Hoffmann I, Becker K, Osten B, Brodde OE.

Br J Pharmacol. 2000 Apr;129(8):1723-31.

29.

Gq/11-coupled receptors and protein synthesis in rat cardiomyocytes: role of Gi-proteins and protein kinase C-isozymes.

Pönicke K, Heinroth-Hoffmann I, Becker K, Osten B, Brodde OE.

Naunyn Schmiedebergs Arch Pharmacol. 1999 Sep;360(3):301-8.

PMID:
10543432
30.

Muscarinic receptors in the failing human heart.

Giessler C, Dhein S, Pönicke K, Brodde OE.

Eur J Pharmacol. 1999 Jun 30;375(1-3):197-202. Review.

PMID:
10443575
31.

Cardiac effects of beta-adrenoceptor antagonists with intrinsic sympathomimetic activity in humans: beta1- and/or beta2-adrenoceptor mediated?

Jakubetz J, Schmuck S, Poller U, Fuchs B, Gorf A, Radke J, Pönicke K, Brodde OE.

J Cardiovasc Pharmacol. 1999 Mar;33(3):461-72.

PMID:
10069683
32.

Terbutaline-induced desensitization of human cardiac beta 2-adrenoceptor-mediated positive inotropic effects: attenuation by ketotifen.

Poller U, Fuchs B, Gorf A, Jakubetz J, Radke J, Pönicke K, Brodde OE.

Cardiovasc Res. 1998 Oct;40(1):211-22.

PMID:
9876334
33.

Mechanism of ET(A)-receptor stimulation-induced increases in intracellular Ca2+ in SK-N-MC cells.

Heinroth-Hoffmann I, Vogelsang M, Schiewe P, Morawietz H, Holtz J, Pönicke K, Brodde OE.

Br J Pharmacol. 1998 Nov;125(6):1202-11.

34.

Effects of uremic plasma on alpha- and beta-adrenoceptor subtypes.

Ferchland A, Rettkowski O, Pönicke K, Deuber HJ, Osten B, Brodde OE.

Nephron. 1998 Sep;80(1):46-50.

PMID:
9730702
35.

[Histamine in tears in allergic rhinoconjunctivitis].

Struck HG, Wicht A, Pönicke K, Lautenschläger C, Lübbe D.

Ophthalmologe. 1998 Apr;95(4):241-6. German.

PMID:
9623261
36.

Endothelin receptors in the failing and nonfailing human heart.

Pönicke K, Vogelsang M, Heinroth M, Becker K, Zolk O, Böhm M, Zerkowski HR, Brodde OE.

Circulation. 1998 Mar 3;97(8):744-51.

37.

Inhibition of mediator release from anaphylactic guinea pig hearts by the novel phospholipase A2 inhibitor 3-(4-octadecylbenzoyl) acrylic acid.

Abate A, Giessler J, Giessler C, Pönicke K, Hirschelmann R, Nuhn P.

Inflamm Res. 1997 Aug;46 Suppl 2:S137-8. No abstract available.

PMID:
9297549
38.

Influence of atropine on the cardiovascular effects of noradrenaline and tyramine in elder volunteers.

Poller U, Schäfers RF, Schmuck S, Jakubetz J, Radke J, Daul AE, Pönicke K, Brodde OE.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Jul;356(1):100-6.

PMID:
9228196
39.

Trophic effect of angiotensin II in neonatal rat cardiomyocytes: role of endothelin-1 and non-myocyte cells.

Pönicke K, Heinroth-Hoffmann I, Becker K, Brodde OE.

Br J Pharmacol. 1997 May;121(1):118-24.

40.

Influence of adrenoceptor and muscarinic receptor blockade on the cardiovascular effects of exogenous noradrenaline and of endogenous noradrenaline released by infused tyramine.

Schäfers RF, Poller U, Pönicke K, Geissler M, Daul AE, Michel MC, Brodde OE.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Feb;355(2):239-49.

PMID:
9050018
41.

Age-dependent changes in cardiac muscarinic receptor function in healthy volunteers.

Poller U, Nedelka G, Radke J, Pönicke K, Brodde OE.

J Am Coll Cardiol. 1997 Jan;29(1):187-93.

42.

Pharmacokinetics of trapidil in patients with chronic liver disease.

Berndt A, Looby M, Pönicke K, Zipprich B, Weiss M.

J Clin Pharmacol. 1996 Oct;36(10):897-902.

PMID:
8930776
43.

Dose-dependent separation of dopaminergic and adrenergic effects of epinine in healthy volunteers.

Daul A, Elter-Schulz M, Poller U, Jockenhövel F, Pönicke K, Boomsma F, Man in't Veld AJ, Schäfes RF, Brodde OE.

Naunyn Schmiedebergs Arch Pharmacol. 1995 Oct;352(4):429-37.

PMID:
8532072
44.

PAF effects on eicosanoid release in neonatal rat cardiomyocytes.

Becker K, Heinroth-Hoffmann I, Giessler C, Pönicke K, Brodde OE.

Prostaglandins Leukot Essent Fatty Acids. 1995 Sep;53(3):197-200.

PMID:
7480082
45.
46.

Relevance of mediators to cardiac parameters of isolated anaphylactic guinea-pig heart.

Mest HJ, Pönicke K, Heinroth-Hoffmann I, Meissner N, Giessler C.

Prostaglandins Leukot Essent Fatty Acids. 1995 Jul;53(1):21-9.

PMID:
7545818
47.

Pharmacokinetics of trapidil (Rocornal) in patients with chronic liver disease.

Berndt A, Pönicke K, Weiss M.

Int J Clin Pharmacol Ther Toxicol. 1992 Nov;30(11):492-3.

PMID:
1490801
48.

[Improvement of the disolution behavior of problem drugs. 22. Preformulations of AR 12463 in absorption models].

Fahr F, Neubert R, Hahn HJ, Pönicke K.

Pharmazie. 1991 Sep;46(9):673. German. No abstract available.

PMID:
1798735
49.

Bioavailability of trapidil tablets.

Weiss M, Sziegoleit W, Pönicke K, Schobess M, Fahr A, Mest HJ.

Arzneimittelforschung. 1989 Sep;39(9):1137-8.

PMID:
2590264
50.

Stimulation of aggregation and thromboxane A2 formation of human platelets by hypoxia.

Pönicke K, Sternitzky R, Mest HJ.

Prostaglandins Leukot Med. 1987 Sep;29(1):49-59.

PMID:
3478738

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