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Items: 17

1.

Data-driven characterization of molecular phenotypes across heterogeneous sample collections.

Mehtonen J, Pölönen P, Häyrynen S, Dufva O, Lin J, Liuksiala T, Granberg K, Lohi O, Hautamäki V, Nykter M, Heinäniemi M.

Nucleic Acids Res. 2019 Jul 26;47(13):e76. doi: 10.1093/nar/gkz281.

2.

Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia.

Kuusanmäki H, Leppä AM, Pölönen P, Kontro M, Dufva O, Deb D, Yadav B, Brück O, Kumar A, Everaus H, Gjertsen BT, Heinäniemi M, Porkka K, Mustjoki S, Heckman CA.

Haematologica. 2019 Jul 11. pii: haematol.2018.214882. doi: 10.3324/haematol.2018.214882. [Epub ahead of print]

3.

Flow Experiences During Visuomotor Skill Acquisition Reflect Deviation From a Power-Law Learning Curve, but Not Overall Level of Skill.

Cowley BU, Palomäki J, Tammi T, Frantsi R, Inkilä VP, Lehtonen N, Pölönen P, Vepsäläinen J, Lappi O.

Front Psychol. 2019 May 15;10:1126. doi: 10.3389/fpsyg.2019.01126. eCollection 2019.

4.

Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies.

Pölönen P, Mehtonen J, Lin J, Liuksiala T, Häyrynen S, Teppo S, Mäkinen A, Kumar A, Malani D, Pohjolainen V, Porkka K, Heckman CA, May P, Hautamäki V, Granberg KJ, Lohi O, Nykter M, Heinäniemi M.

Cancer Res. 2019 May 15;79(10):2466-2479. doi: 10.1158/0008-5472.CAN-18-2970. Epub 2019 Apr 2.

PMID:
30940663
5.

Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture.

Bouvy-Liivrand M, Hernández de Sande A, Pölönen P, Mehtonen J, Vuorenmaa T, Niskanen H, Sinkkonen L, Kaikkonen MU, Heinäniemi M.

Nucleic Acids Res. 2017 Nov 16;45(20):12054. doi: 10.1093/nar/gkx909. No abstract available.

6.

Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture.

Bouvy-Liivrand M, Hernández de Sande A, Pölönen P, Mehtonen J, Vuorenmaa T, Niskanen H, Sinkkonen L, Kaikkonen MU, Heinäniemi M.

Nucleic Acids Res. 2017 Sep 29;45(17):9837-9849. doi: 10.1093/nar/gkx680.

7.

In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL.

Laukkanen S, Grönroos T, Pölönen P, Kuusanmäki H, Mehtonen J, Cloos J, Ossenkoppele G, Gjertsen B, Øystein B, Heckman C, Heinäniemi M, Kontro M, Lohi O.

Blood Cancer J. 2017 Sep 8;7(9):e604. doi: 10.1038/bcj.2017.87. No abstract available.

8.

The Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs.

Kuosmanen SM, Viitala S, Laitinen T, Peräkylä M, Pölönen P, Kansanen E, Leinonen H, Raju S, Wienecke-Baldacchino A, Närvänen A, Poso A, Heinäniemi M, Heikkinen S, Levonen AL.

Nucleic Acids Res. 2016 Feb 29;44(4):1760-75. doi: 10.1093/nar/gkw052. Epub 2016 Jan 29.

9.

Dysregulation of the Keap1-Nrf2 pathway in cancer.

Leinonen HM, Kansanen E, Pölönen P, Heinäniemi M, Levonen AL.

Biochem Soc Trans. 2015 Aug;43(4):645-9. doi: 10.1042/BST20150048. Epub 2015 Aug 3. Review.

PMID:
26551706
10.

Role of the Keap1-Nrf2 pathway in cancer.

Leinonen HM, Kansanen E, Pölönen P, Heinäniemi M, Levonen AL.

Adv Cancer Res. 2014;122:281-320. doi: 10.1016/B978-0-12-420117-0.00008-6. Review.

PMID:
24974185
11.

Levosimendan reduces heart failure after cardiac surgery: a prospective, randomized, placebo-controlled trial.

Lahtinen P, Pitkänen O, Pölönen P, Turpeinen A, Kiviniemi V, Uusaro A.

Crit Care Med. 2011 Oct;39(10):2263-70. doi: 10.1097/CCM.0b013e3182227b97.

PMID:
21666445
12.
13.

Midlatency auditory-evoked potentials in the assessment of sedation in cardiac surgery patients.

Musialowicz T, Hynynen M, Yppärilä H, Pölönen P, Ruokonen E, Jakob SM.

J Cardiothorac Vasc Anesth. 2004 Oct;18(5):559-62.

PMID:
15578465
14.

A prospective, randomized study of goal-oriented hemodynamic therapy in cardiac surgical patients.

Pölönen P, Ruokonen E, Hippeläinen M, Pöyhönen M, Takala J.

Anesth Analg. 2000 May;90(5):1052-9.

PMID:
10781452
15.

Relationship between intra- and postoperative oxygen transport and prolonged intensive care after cardiac surgery: a prospective study.

Pölönen P, Hippeläinen M, Takala R, Ruokonen E, Takala J.

Acta Anaesthesiol Scand. 1997 Aug;41(7):810-7.

PMID:
9265921
16.

Effect of digital edge-enhancement on the visibility of normal parenchymal lung markings.

Vehmas T, Korhola O, Pölönen P, Knuutila T, Kivisaari A, Holmberg J, Bondestam S, Tikkanen H.

Eur J Radiol. 1994 May;18(2):109-12.

PMID:
8055980
17.

Observed lung markings in normal chest roentgenograms.

Vehmas T, Tikkanen H, Bondestam S, Holmberg J, Kivisaari A, Knuutila T, Pölönen P, Korhola O.

Rofo. 1993 Jul;159(1):50-3.

PMID:
8334258

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