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Items: 1 to 50 of 178

1.

Tmprss2 knock-out mice are resistant to H10 influenza A virus pathogenesis.

Lambertz RLO, Gerhauser I, Nehlmeier I, Leist SR, Kollmus H, Pöhlmann S, Schughart K.

J Gen Virol. 2019 May 17. doi: 10.1099/jgv.0.001274. [Epub ahead of print]

PMID:
31099738
2.

Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins.

Braun E, Hotter D, Koepke L, Zech F, Groß R, Sparrer KMJ, Müller JA, Pfaller CK, Heusinger E, Wombacher R, Sutter K, Dittmer U, Winkler M, Simmons G, Jakobsen MR, Conzelmann KK, Pöhlmann S, Münch J, Fackler OT, Kirchhoff F, Sauter D.

Cell Rep. 2019 May 14;27(7):2092-2104.e10. doi: 10.1016/j.celrep.2019.04.063.

3.

IFITMs mediate viral evasion in acute and chronic hepatitis C virus infection.

Wrensch F, Ligat G, Heydmann L, Schuster C, Zeisel MB, Pessaux P, Habersetzer F, King BJ, Tarr AW, Ball JK, Winkler M, Pöhlmann S, Keck ZY, Foung SKH, Baumert TF.

Hepatology. 2019 May 7. doi: 10.1002/hep.30699. [Epub ahead of print]

PMID:
31062385
4.

Calu-3 cells are largely resistant to entry driven by filovirus glycoproteins and the entry defect can be rescued by directed expression of DC-SIGN or cathepsin L.

González-Hernández M, Müller A, Hoenen T, Hoffmann M, Pöhlmann S.

Virology. 2019 Apr 3;532:22-29. doi: 10.1016/j.virol.2019.03.020. [Epub ahead of print]

PMID:
30999160
5.

Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins.

Plegge T, Spiegel M, Krüger N, Nehlmeier I, Winkler M, González Hernández M, Pöhlmann S.

PLoS One. 2019 Apr 11;14(4):e0214968. doi: 10.1371/journal.pone.0214968. eCollection 2019.

6.

Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance.

Korniy N, Goyal A, Hoffmann M, Samatova E, Peske F, Pöhlmann S, Rodnina MV.

Nucleic Acids Res. 2019 Jun 4;47(10):5210-5222. doi: 10.1093/nar/gkz202.

7.

Distinct contribution of Rac1 expression in cardiomyocytes to anthracycline-induced cardiac injury.

Henninger C, Pohlmann S, Ziegler V, Ohlig J, Schmitt J, Fritz G.

Biochem Pharmacol. 2019 Jun;164:82-93. doi: 10.1016/j.bcp.2019.03.038. Epub 2019 Mar 29.

PMID:
30936017
8.

Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors.

Zapatero-Belinchón FJ, Dietzel E, Dolnik O, Döhner K, Costa R, Hertel B, Veselkova B, Kirui J, Klintworth A, Manns MP, Pöhlmann S, Pietschmann T, Krey T, Ciesek S, Gerold G, Sodeik B, Becker S, von Hahn T.

Viruses. 2019 Mar 19;11(3). pii: E275. doi: 10.3390/v11030275.

9.

A system for production of defective interfering particles in the absence of infectious influenza A virus.

Bdeir N, Arora P, Gärtner S, Hoffmann M, Reichl U, Pöhlmann S, Winkler M.

PLoS One. 2019 Mar 1;14(3):e0212757. doi: 10.1371/journal.pone.0212757. eCollection 2019.

10.

Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner.

Nehls J, Businger R, Hoffmann M, Brinkmann C, Fehrenbacher B, Schaller M, Maurer B, Schönfeld C, Kramer D, Hailfinger S, Pöhlmann S, Schindler M.

Cell Rep. 2019 Feb 12;26(7):1841-1853.e6. doi: 10.1016/j.celrep.2019.01.065.

11.

Disease Manifestation and Viral Sequences in a Bonobo More Than 30 Years after Papillomavirus Infection.

Hoffmann M, Schütze E, Bernhard A, Schlaphoff L, Kaul A, Schöniger S, Pöhlmann S.

Pathogens. 2019 Jan 26;8(1). pii: E13. doi: 10.3390/pathogens8010013.

12.

Utilizing a Prototype Patient-Controlled Electronic Health Record in Germany: Qualitative Analysis of User-Reported Perceptions and Perspectives.

Poss-Doering R, Kunz A, Pohlmann S, Hofmann H, Kiel M, Winkler EC, Ose D, Szecsenyi J.

JMIR Form Res. 2018 Aug 3;2(2):e10411. doi: 10.2196/10411.

13.

Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells.

Hoffmann M, Nehlmeier I, Brinkmann C, Krähling V, Behner L, Moldenhauer AS, Krüger N, Nehls J, Schindler M, Hoenen T, Maisner A, Becker S, Pöhlmann S.

J Virol. 2019 Jan 17;93(3). pii: e01821-18. doi: 10.1128/JVI.01821-18. Print 2019 Feb 1.

PMID:
30429347
14.

Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein.

Kleine-Weber H, Elzayat MT, Hoffmann M, Pöhlmann S.

Sci Rep. 2018 Nov 9;8(1):16597. doi: 10.1038/s41598-018-34859-w.

15.

Mutations in the Spike Protein of Middle East Respiratory Syndrome Coronavirus Transmitted in Korea Increase Resistance to Antibody-Mediated Neutralization.

Kleine-Weber H, Elzayat MT, Wang L, Graham BS, Müller MA, Drosten C, Pöhlmann S, Hoffmann M.

J Virol. 2019 Jan 4;93(2). pii: e01381-18. doi: 10.1128/JVI.01381-18. Print 2019 Jan 15.

PMID:
30404801
16.

TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1.

Zmora P, Hoffmann M, Kollmus H, Moldenhauer AS, Danov O, Braun A, Winkler M, Schughart K, Pöhlmann S.

J Biol Chem. 2018 Sep 7;293(36):13863-13873. doi: 10.1074/jbc.RA118.001273. Epub 2018 Jul 5.

PMID:
29976755
17.

Hepatic Rac1 GTPase contributes to liver-mediated basal immune homeostasis and LPS-induced endotoxemia.

Pohlmann S, Scheu S, Ziegler V, Schupp N, Henninger C, Fritz G.

Biochim Biophys Acta Mol Cell Res. 2018 Sep;1865(9):1277-1292. doi: 10.1016/j.bbamcr.2018.06.007. Epub 2018 Jun 20.

PMID:
29932987
18.

Cell Entry of Influenza A Viruses: Sweet Talk between HA and CaV1.2.

Hoffmann M, Pöhlmann S.

Cell Host Microbe. 2018 Jun 13;23(6):697-699. doi: 10.1016/j.chom.2018.05.019.

19.

A GXXXA Motif in the Transmembrane Domain of the Ebola Virus Glycoprotein Is Required for Tetherin Antagonism.

González-Hernández M, Hoffmann M, Brinkmann C, Nehls J, Winkler M, Schindler M, Pöhlmann S.

J Virol. 2018 Jun 13;92(13). pii: e00403-18. doi: 10.1128/JVI.00403-18. Print 2018 Jul 1.

20.

Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced Immunosuppression.

Smirnov A, Pohlmann S, Nehring M, Ali S, Mann-Nüttel R, Scheu S, Antoni AC, Hansen W, Büettner M, Gardiasch MJ, Westendorf AM, Wirsdörfer F, Pastille E, Dudda M, Flohé SB.

Front Immunol. 2017 Nov 23;8:1622. doi: 10.3389/fimmu.2017.01622. eCollection 2017.

21.

The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells.

Brinkmann C, Hoffmann M, Lübke A, Nehlmeier I, Krämer-Kühl A, Winkler M, Pöhlmann S.

PLoS One. 2017 Dec 7;12(12):e0189073. doi: 10.1371/journal.pone.0189073. eCollection 2017.

22.

Three-dimensional segmentation of breast masses from digital breast tomosynthesis images.

Pöhlmann STL, Lim YY, Harkness E, Pritchard S, Taylor CJ, Astley SM.

J Med Imaging (Bellingham). 2017 Jul;4(3):034007. doi: 10.1117/1.JMI.4.3.034007. Epub 2017 Sep 19.

23.

Dissecting Multivalent Lectin-Carbohydrate Recognition Using Polyvalent Multifunctional Glycan-Quantum Dots.

Guo Y, Nehlmeier I, Poole E, Sakonsinsiri C, Hondow N, Brown A, Li Q, Li S, Whitworth J, Li Z, Yu A, Brydson R, Turnbull WB, Pöhlmann S, Zhou D.

J Am Chem Soc. 2017 Aug 30;139(34):11833-11844. doi: 10.1021/jacs.7b05104. Epub 2017 Aug 17.

24.

Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.

Reinke LM, Spiegel M, Plegge T, Hartleib A, Nehlmeier I, Gierer S, Hoffmann M, Hofmann-Winkler H, Winkler M, Pöhlmann S.

PLoS One. 2017 Jun 21;12(6):e0179177. doi: 10.1371/journal.pone.0179177. eCollection 2017.

25.

Preoperative implant selection for unilateral breast reconstruction using 3D imaging with the Microsoft Kinect sensor.

Pöhlmann STL, Harkness E, Taylor CJ, Gandhi A, Astley SM.

J Plast Reconstr Aesthet Surg. 2017 Aug;70(8):1059-1067. doi: 10.1016/j.bjps.2017.04.005. Epub 2017 Apr 23.

PMID:
28595842
26.

[Personal health records on the Internet. A narrative review of attitudes, expectations, utilization and effects on health outcomes].

Ose D, Baudendistel I, Pohlmann S, Winkler EC, Kunz A, Szecsenyi J.

Z Evid Fortbild Qual Gesundhwes. 2017 May;122:9-21. doi: 10.1016/j.zefq.2017.04.006. Epub 2017 May 10. Review. German.

PMID:
28499764
27.

Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin.

Zmora P, Molau-Blazejewska P, Bertram S, Walendy-Gnirß K, Nehlmeier I, Hartleib A, Moldenhauer AS, Konzok S, Dehmel S, Sewald K, Brinkmann C, Curths C, Knauf S, Gruber J, Mätz-Rensing K, Dahlmann F, Braun A, Pöhlmann S.

PLoS One. 2017 May 11;12(5):e0176597. doi: 10.1371/journal.pone.0176597. eCollection 2017.

28.

Herpes B virus replication and viral lesions in the liver of a cynomolgus macaque which died from severe disease with rapid onset.

Pöhlmann S, Suntz M, Akimkin V, Bleyer M, Kaul A.

J Med Primatol. 2017 Oct;46(5):256-259. doi: 10.1111/jmp.12269. Epub 2017 Apr 25.

PMID:
28439900
29.

pH Optimum of Hemagglutinin-Mediated Membrane Fusion Determines Sensitivity of Influenza A Viruses to the Interferon-Induced Antiviral State and IFITMs.

Gerlach T, Hensen L, Matrosovich T, Bergmann J, Winkler M, Peteranderl C, Klenk HD, Weber F, Herold S, Pöhlmann S, Matrosovich M.

J Virol. 2017 May 12;91(11). pii: e00246-17. doi: 10.1128/JVI.00246-17. Print 2017 Jun 1.

30.

Rhesus macaque IFITM3 gene polymorphisms and SIV infection.

Winkler M, Gärtner S, Wrensch F, Krawczak M, Sauermann U, Pöhlmann S.

PLoS One. 2017 Mar 3;12(3):e0172847. doi: 10.1371/journal.pone.0172847. eCollection 2017.

31.

A Personal Electronic Health Record: Study Protocol of a Feasibility Study on Implementation in a Real-World Health Care Setting.

Ose D, Kunz A, Pohlmann S, Hofmann H, Qreini M, Krisam J, Uhlmann L, Jacke C, Winkler EC, Salize HJ, Szecsenyi J.

JMIR Res Protoc. 2017 Mar 2;6(3):e33. doi: 10.2196/resprot.6314.

32.

A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry.

Hoffmann M, Crone L, Dietzel E, Paijo J, González-Hernández M, Nehlmeier I, Kalinke U, Becker S, Pöhlmann S.

J Virol. 2017 Apr 13;91(9). pii: e00177-17. doi: 10.1128/JVI.00177-17. Print 2017 May 1.

33.

Evaluation of Kinect 3D Sensor for Healthcare Imaging.

Pöhlmann ST, Harkness EF, Taylor CJ, Astley SM.

J Med Biol Eng. 2016;36(6):857-870. doi: 10.1007/s40846-016-0184-2. Epub 2016 Dec 9.

34.

Evidence that Processing of the Severe Fever with Thrombocytopenia Syndrome Virus Gn/Gc Polyprotein Is Critical for Viral Infectivity and Requires an Internal Gc Signal Peptide.

Plegge T, Hofmann-Winkler H, Spiegel M, Pöhlmann S.

PLoS One. 2016 Nov 17;11(11):e0166013. doi: 10.1371/journal.pone.0166013. eCollection 2016.

35.

Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins.

Wrensch F, Hoffmann M, Gärtner S, Nehlmeier I, Winkler M, Pöhlmann S.

J Virol. 2017 Jan 3;91(2). pii: e01488-16. doi: 10.1128/JVI.01488-16. Print 2017 Jan 15.

36.

The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies.

Brinkmann C, Nehlmeier I, Walendy-Gnirß K, Nehls J, González Hernández M, Hoffmann M, Qiu X, Takada A, Schindler M, Pöhlmann S.

J Virol. 2016 Nov 28;90(24):11075-11086. Print 2016 Dec 15.

37.

Strengthening Interprofessional Requirements Engineering Through Action Sheets: A Pilot Study.

Kunz A, Pohlmann S, Heinze O, Brandner A, Reiß C, Kamradt M, Szecsenyi J, Ose D.

JMIR Hum Factors. 2016 Oct 18;3(2):e25.

38.

Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions.

Guo Y, Sakonsinsiri C, Nehlmeier I, Fascione MA, Zhang H, Wang W, Pöhlmann S, Turnbull WB, Zhou D.

Angew Chem Weinheim Bergstr Ger. 2016 Apr 4;128(15):4816-4820. Epub 2016 Mar 15.

39.

The Role of Phlebovirus Glycoproteins in Viral Entry, Assembly and Release.

Spiegel M, Plegge T, Pöhlmann S.

Viruses. 2016 Jul 21;8(7). pii: E202. doi: 10.3390/v8070202. Review.

40.

The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.

Hoffmann M, Krüger N, Zmora P, Wrensch F, Herrler G, Pöhlmann S.

PLoS One. 2016 Mar 30;11(3):e0152134. doi: 10.1371/journal.pone.0152134. eCollection 2016.

41.

Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions.

Guo Y, Sakonsinsiri C, Nehlmeier I, Fascione MA, Zhang H, Wang W, Pöhlmann S, Turnbull WB, Zhou D.

Angew Chem Int Ed Engl. 2016 Apr 4;55(15):4738-42. doi: 10.1002/anie.201600593. Epub 2016 Mar 16.

42.

Clinical tests and magnetic resonance imaging have limited diagnostic value for triangular fibrocartilaginous complex lesions.

Schmauss D, Pöhlmann S, Lohmeyer JA, Germann G, Bickert B, Megerle K.

Arch Orthop Trauma Surg. 2016 Jun;136(6):873-80. doi: 10.1007/s00402-016-2441-9. Epub 2016 Mar 11.

PMID:
26969464
43.

The Glycoproteins of All Filovirus Species Use the Same Host Factors for Entry into Bat and Human Cells but Entry Efficiency Is Species Dependent.

Hoffmann M, González Hernández M, Berger E, Marzi A, Pöhlmann S.

PLoS One. 2016 Feb 22;11(2):e0149651. doi: 10.1371/journal.pone.0149651. eCollection 2016.

44.

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases.

Kühn N, Bergmann S, Kösterke N, Lambertz RLO, Keppner A, van den Brand JMA, Pöhlmann S, Weiß S, Hummler E, Hatesuer B, Schughart K.

J Virol. 2016 Apr 14;90(9):4298-4307. doi: 10.1128/JVI.02693-15. Print 2016 May.

45.

TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.

Zmora P, Moldenhauer AS, Hofmann-Winkler H, Pöhlmann S.

PLoS One. 2015 Sep 17;10(9):e0138380. doi: 10.1371/journal.pone.0138380. eCollection 2015.

46.

Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques.

Karsten CB, Buettner FF, Cajic S, Nehlmeier I, Neumann B, Klippert A, Sauermann U, Reichl U, Gerardy-Schahn R, Rapp E, Stahl-Hennig C, Pöhlmann S.

J Virol. 2015 Nov;89(22):11727-33. doi: 10.1128/JVI.01358-15. Epub 2015 Sep 9.

47.

Tetherin Sensitivity of Influenza A Viruses Is Strain Specific: Role of Hemagglutinin and Neuraminidase.

Gnirß K, Zmora P, Blazejewska P, Winkler M, Lins A, Nehlmeier I, Gärtner S, Moldenhauer AS, Hofmann-Winkler H, Wolff T, Schindler M, Pöhlmann S.

J Virol. 2015 Sep;89(18):9178-88. doi: 10.1128/JVI.00615-15. Epub 2015 Jun 24.

48.

Invasive Surgery Impairs the Regulatory Function of Human CD56 bright Natural Killer Cells in Response to Staphylococcus aureus. Suppression of Interferon-γ Synthesis.

Reinhardt R, Pohlmann S, Kleinertz H, Hepner-Schefczyk M, Paul A, Flohé SB.

PLoS One. 2015 Jun 19;10(6):e0130155. doi: 10.1371/journal.pone.0130155. eCollection 2015.

49.

Interferon-Induced Transmembrane Protein-Mediated Inhibition of Host Cell Entry of Ebolaviruses.

Wrensch F, Karsten CB, Gnirß K, Hoffmann M, Lu K, Takada A, Winkler M, Simmons G, Pöhlmann S.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S210-8. doi: 10.1093/infdis/jiv255. Epub 2015 Jun 1.

50.

Analysis of Ebola Virus Entry Into Macrophages.

Dahlmann F, Biedenkopf N, Babler A, Jahnen-Dechent W, Karsten CB, Gnirß K, Schneider H, Wrensch F, O'Callaghan CA, Bertram S, Herrler G, Becker S, Pöhlmann S, Hofmann-Winkler H.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S247-57. doi: 10.1093/infdis/jiv140. Epub 2015 Apr 14.

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