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Best matches for Pêgo AP[au]:

Delivering siRNA with Dendrimers: In Vivo Applications. Leiro V et al. Curr Gene Ther. (2017)

BDNF gene delivery mediated by neuron-targeted nanoparticles is neuroprotective in peripheral nerve injury. Lopes CDF et al. Biomaterials. (2017)

Biomimetic synthetic self-assembled hydrogels for cell transplantation. Barros D et al. Curr Top Med Chem. (2015)

Search results

Items: 1 to 50 of 64

1.

An affinity-based approach to engineer laminin-presenting cell instructive microenvironments.

Barros D, Parreira P, Furtado J, Ferreira-da-Silva F, Conde-Sousa E, García AJ, Martins MCL, Amaral IF, Pêgo AP.

Biomaterials. 2019 Feb;192:601-611. doi: 10.1016/j.biomaterials.2018.10.039. Epub 2018 Dec 1.

PMID:
30509501
2.

Molecular Recognition Force Spectroscopy for Probing Cell Targeted Nanoparticles In Vitro.

Gomes CP, Oliveira H, Ebner A, Hinterdorfer P, Pêgo AP.

Methods Mol Biol. 2019;1886:327-341. doi: 10.1007/978-1-4939-8894-5_19.

PMID:
30374877
3.

PAMAM dendrimers: blood-brain barrier transport and neuronal uptake after focal brain ischemia.

Santos SD, Xavier M, Leite DM, Moreira DA, Custódio B, Torrado M, Castro R, Leiro V, Rodrigues J, Tomás H, Pêgo AP.

J Control Release. 2018 Dec 10;291:65-79. doi: 10.1016/j.jconrel.2018.10.006. Epub 2018 Oct 9.

PMID:
30308255
4.

Synthetic matrix enhances transplanted satellite cell engraftment in dystrophic and aged skeletal muscle with comorbid trauma.

Han WM, Anderson SE, Mohiuddin M, Barros D, Nakhai SA, Shin E, Amaral IF, Pêgo AP, García AJ, Jang YC.

Sci Adv. 2018 Aug 15;4(8):eaar4008. doi: 10.1126/sciadv.aar4008. eCollection 2018 Aug.

5.

Fine tuning neuronal targeting of nanoparticles by adjusting the ligand grafting density and combining PEG spacers of different length.

Pereira Gomes C, Leiro V, Ferreira Lopes CD, Spencer AP, Pêgo AP.

Acta Biomater. 2018 Sep 15;78:247-259. doi: 10.1016/j.actbio.2018.08.005. Epub 2018 Aug 7.

PMID:
30092376
6.

Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in Spinal Cord Injury.

Moreno PMD, Ferreira AR, Salvador D, Rodrigues MT, Torrado M, Carvalho ED, Tedebark U, Sousa MM, Amaral IF, Wengel J, Pêgo AP.

Mol Ther Nucleic Acids. 2018 Jun 1;11:393-406. doi: 10.1016/j.omtn.2018.03.009. Epub 2018 Mar 20.

7.

Scavenging activity of Magnéli phases as a function of Ti4+/Ti3+ ratios.

Canillas M, Chinarro E, Pêgo AP, Moreno B.

Chem Commun (Camb). 2017 Sep 21;53(76):10580-10583. doi: 10.1039/c7cc05862d.

PMID:
28895967
8.

Ibuprofen-loaded fibrous patches-taming inhibition at the spinal cord injury site.

Pires LR, Lopes CDF, Salvador D, Rocha DN, Pêgo AP.

J Mater Sci Mater Med. 2017 Sep 11;28(10):157. doi: 10.1007/s10856-017-5967-7.

PMID:
28894995
9.

Atomic Force Microscopy as a Tool to Assess the Specificity of Targeted Nanoparticles in Biological Models of High Complexity.

Gomes CP, Lopes CDF, Leitner M, Ebner A, Hinterdorfer P, Pêgo AP.

Adv Healthc Mater. 2017 Nov;6(21). doi: 10.1002/adhm.201700597. Epub 2017 Jul 28.

PMID:
28752592
10.

Fibrin functionalization with synthetic adhesive ligands interacting with α6β1 integrin receptor enhance neurite outgrowth of embryonic stem cell-derived neural stem/progenitors.

Silva J, Bento AR, Barros D, Laundos TL, Sousa SR, Quelhas P, Sousa MM, Pêgo AP, Amaral IF.

Acta Biomater. 2017 Sep 1;59:243-256. doi: 10.1016/j.actbio.2017.07.013. Epub 2017 Jul 8.

PMID:
28694236
11.

Delivering siRNA with Dendrimers: In Vivo Applications.

Leiro V, Santos SD, Pego AP.

Curr Gene Ther. 2017;17(2):105-119. doi: 10.2174/1566523217666170510160527. Review.

PMID:
28494741
12.

BDNF gene delivery mediated by neuron-targeted nanoparticles is neuroprotective in peripheral nerve injury.

Lopes CDF, Gonçalves NP, Gomes CP, Saraiva MJ, Pêgo AP.

Biomaterials. 2017 Mar;121:83-96. doi: 10.1016/j.biomaterials.2016.12.025. Epub 2016 Dec 24.

PMID:
28081461
13.

Three-dimensional culture of single embryonic stem-derived neural/stem progenitor cells in fibrin hydrogels: neuronal network formation and matrix remodelling.

Bento AR, Quelhas P, Oliveira MJ, Pêgo AP, Amaral IF.

J Tissue Eng Regen Med. 2017 Dec;11(12):3494-3507. doi: 10.1002/term.2262. Epub 2016 Dec 29.

PMID:
28032468
14.

Microfluidic-based platform to mimic the in vivo peripheral administration of neurotropic nanoparticles.

Lopes CD, Gomes CP, Neto E, Sampaio P, Aguiar P, Pêgo AP.

Nanomedicine (Lond). 2016 Dec;11(24):3205-3221. Epub 2016 Nov 10.

PMID:
27830593
15.

A high-throughput bioimaging study to assess the impact of chitosan-based nanoparticle degradation on DNA delivery performance.

Gomes CP, Varela-Moreira A, Leiro V, Lopes CDF, Moreno PMD, Gomez-Lazaro M, Pêgo AP.

Acta Biomater. 2016 Dec;46:129-140. doi: 10.1016/j.actbio.2016.09.037. Epub 2016 Sep 26.

PMID:
27686038
16.

Antisense Oligonucleotides Modulating Activation of a Nonsense-Mediated RNA Decay Switch Exon in the ATM Gene.

Kralovicova J, Moreno PM, Cross NC, Pêgo AP, Vorechovsky I.

Nucleic Acid Ther. 2016 Dec;26(6):392-400. Epub 2016 Sep 22.

17.

In vivo targeted gene delivery to peripheral neurons mediated by neurotropic poly(ethylene imine)-based nanoparticles.

Lopes CD, Oliveira H, Estevão I, Pires LR, Pêgo AP.

Int J Nanomedicine. 2016 Jun 8;11:2675-83. doi: 10.2147/IJN.S104374. eCollection 2016. Erratum in: Int J Nanomedicine. 2017 Aug 07;12 :5631.

18.

High-throughput platforms for the screening of new therapeutic targets for neurodegenerative diseases.

Rocha DN, Carvalho ED, Pêgo AP.

Drug Discov Today. 2016 Sep;21(9):1355-1366. doi: 10.1016/j.drudis.2016.05.005. Epub 2016 May 10. Review.

PMID:
27178019
19.

Rotary orbital suspension culture of embryonic stem cell-derived neural stem/progenitor cells: impact of hydrodynamic culture on aggregate yield, morphology and cell phenotype.

Laundos TL, Silva J, Assunção M, Quelhas P, Monteiro C, Oliveira C, Oliveira MJ, Pêgo AP, Amaral IF.

J Tissue Eng Regen Med. 2017 Aug;11(8):2227-2240. doi: 10.1002/term.2121. Epub 2016 Feb 15.

PMID:
26880706
20.

Bridging the lesion-engineering a permissive substrate for nerve regeneration.

Pires LR, Pêgo AP.

Regen Biomater. 2015 Sep;2(3):203-14. doi: 10.1093/rb/rbv012. Epub 2015 Aug 10.

21.

Delivery of Splice Switching Oligonucleotides by Amphiphilic Chitosan-Based Nanoparticles.

Moreno PM, Santos JC, Gomes CP, Varela-Moreira A, Costa A, Leiro V, Mansur H, Pêgo AP.

Mol Pharm. 2016 Feb 1;13(2):344-56. doi: 10.1021/acs.molpharmaceut.5b00538. Epub 2016 Jan 11.

PMID:
26702499
22.

Extracellular environment contribution to astrogliosis-lessons learned from a tissue engineered 3D model of the glial scar.

Rocha DN, Ferraz-Nogueira JP, Barrias CC, Relvas JB, Pêgo AP.

Front Cell Neurosci. 2015 Sep 29;9:377. doi: 10.3389/fncel.2015.00377. eCollection 2015.

23.

Functionalized chitosan derivatives as nonviral vectors: physicochemical properties of acylated N,N,N-trimethyl chitosan/oligonucleotide nanopolyplexes.

Santos JC, Moreno PM, Mansur AA, Leiro V, Mansur HS, Pêgo AP.

Soft Matter. 2015 Nov 7;11(41):8113-25. doi: 10.1039/c5sm01403d.

PMID:
26335751
24.

Seeing is believing but quantifying is deciding.

Lopes CD, Gomez-Lazaro M, Pêgo AP.

Nanomedicine (Lond). 2015;10(15):2307-10. doi: 10.2217/nnm.15.101. Epub 2015 Jul 31. No abstract available.

25.

Biomimetic synthetic self-assembled hydrogels for cell transplantation.

Barros D, Amaral IF, Pêgo AP.

Curr Top Med Chem. 2015;15(13):1209-26. Review.

PMID:
25858129
26.

The Present and the Future of Degradable Dendrimers and Derivatives in Theranostics.

Leiro V, Garcia JP, Tomás H, Pêgo AP.

Bioconjug Chem. 2015 Jul 15;26(7):1182-97. doi: 10.1021/bc5006224. Epub 2015 Mar 31. Review.

PMID:
25826129
27.

The role of the surface on microglia function: implications for central nervous system tissue engineering.

Pires LR, Rocha DN, Ambrosio L, Pêgo AP.

J R Soc Interface. 2015 Feb 6;12(103). pii: 20141224. doi: 10.1098/rsif.2014.1224.

28.

Therapeutic antisense oligonucleotides against cancer: hurdling to the clinic.

Moreno PM, Pêgo AP.

Front Chem. 2014 Oct 14;2:87. doi: 10.3389/fchem.2014.00087. eCollection 2014.

29.

Modified-chitosan/siRNA nanoparticles downregulate cellular CDX2 expression and cross the gastric mucus barrier.

Sadio A, Gustafsson JK, Pereira B, Gomes CP, Hansson GC, David L, Pêgo AP, Almeida R.

PLoS One. 2014 Jun 12;9(6):e99449. doi: 10.1371/journal.pone.0099449. eCollection 2014.

30.

Poly(trimethylene carbonate-co-ε-caprolactone) promotes axonal growth.

Rocha DN, Brites P, Fonseca C, Pêgo AP.

PLoS One. 2014 Feb 27;9(2):e88593. doi: 10.1371/journal.pone.0088593. eCollection 2014.

31.

Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA.

Bordeira-Carriço R, Ferreira D, Mateus DD, Pinheiro H, Pêgo AP, Santos MA, Oliveira C.

Eur J Hum Genet. 2014 Sep;22(9):1085-92. doi: 10.1038/ejhg.2013.292. Epub 2014 Jan 15.

32.

Ibuprofen-loaded poly(trimethylene carbonate-co-ε-caprolactone) electrospun fibres for nerve regeneration.

Pires LR, Guarino V, Oliveira MJ, Ribeiro CC, Barbosa MA, Ambrosio L, Pêgo AP.

J Tissue Eng Regen Med. 2016 Mar;10(3):E154-66. doi: 10.1002/term.1792. Epub 2013 Aug 16.

PMID:
23950030
33.

Kinetics and isotherm of fibronectin adsorption to three-dimensional porous chitosan scaffolds explored by ¹²⁵I-radiolabelling.

Amaral IF, Sousa SR, Neiva I, Marcos-Silva L, Kirkpatrick CJ, Barbosa MA, Pêgo AP.

Biomatter. 2013 Apr-Jun;3(2). pii: e24791. doi: 10.4161/biom.24791. Epub 2013 Apr 29.

34.

Hyaluronic acid/chitosan multilayer coatings on neuronal implants for localized delivery of siRNA nanoplexes.

Hartmann H, Hossfeld S, Schlosshauer B, Mittnacht U, Pêgo AP, Dauner M, Doser M, Stoll D, Krastev R.

J Control Release. 2013 Jun 28;168(3):289-97. doi: 10.1016/j.jconrel.2013.03.026. Epub 2013 Apr 4.

PMID:
23562632
35.

A new strategy based on SmRho protein loaded chitosan nanoparticles as a candidate oral vaccine against schistosomiasis.

Oliveira CR, Rezende CM, Silva MR, Pêgo AP, Borges O, Goes AM.

PLoS Negl Trop Dis. 2012;6(11):e1894. doi: 10.1371/journal.pntd.0001894. Epub 2012 Nov 29.

36.

Endothelialization of chitosan porous conduits via immobilization of a recombinant fibronectin fragment (rhFNIII7-10).

Amaral IF, Neiva I, Ferreira da Silva F, Sousa SR, Piloto AM, Lopes CD, Barbosa MA, Kirkpatrick CJ, Pêgo AP.

Acta Biomater. 2013 Mar;9(3):5643-52. doi: 10.1016/j.actbio.2012.10.029. Epub 2012 Oct 29.

PMID:
23117145
37.

Cancer syndromes and therapy by stop-codon readthrough.

Bordeira-Carriço R, Pêgo AP, Santos M, Oliveira C.

Trends Mol Med. 2012 Nov;18(11):667-78. doi: 10.1016/j.molmed.2012.09.004. Epub 2012 Oct 6. Review.

PMID:
23044248
38.

Regenerative medicine for the treatment of spinal cord injury: more than just promises?

Pêgo AP, Kubinova S, Cizkova D, Vanicky I, Mar FM, Sousa MM, Sykova E.

J Cell Mol Med. 2012 Nov;16(11):2564-82. doi: 10.1111/j.1582-4934.2012.01603.x. Review.

39.

Oral vaccination based on DNA-chitosan nanoparticles against Schistosoma mansoni infection.

Oliveira CR, Rezende CM, Silva MR, Borges OM, Pêgo AP, Goes AM.

ScientificWorldJournal. 2012;2012:938457. doi: 10.1100/2012/938457. Epub 2012 Apr 22.

40.

A novel nanoparticle delivery system for in vivo targeting of the sciatic nerve: impact on regeneration.

Gonçalves NP, Oliveira H, Pêgo AP, Saraiva MJ.

Nanomedicine (Lond). 2012 Aug;7(8):1167-80. doi: 10.2217/nnm.11.188. Epub 2012 Apr 4.

PMID:
22475646
41.

Imidazole-grafted chitosan-mediated gene delivery: in vitro study on transfection, intracellular trafficking and degradation.

Pires LR, Oliveira H, Barrias CC, Sampaio P, Pereira AJ, Maiato H, Simões S, Pêgo AP.

Nanomedicine (Lond). 2011 Nov;6(9):1499-512. doi: 10.2217/nnm.11.51. Epub 2011 Oct 20.

PMID:
22011312
42.

Scientists' perception of ethical issues in nanomedicine: a case study.

Silva Costa H, Sethe S, Pêgo AP, Olsson IA.

Nanomedicine (Lond). 2011 Jun;6(4):681-91. doi: 10.2217/nnm.11.9. Epub 2011 Apr 20.

PMID:
21506689
43.

Molecular recognition force spectroscopy: a new tool to tailor targeted nanoparticles.

Oliveira H, Rangl M, Ebner A, Mayer B, Hinterdorfer P, Pêgo AP.

Small. 2011 May 9;7(9):1236-41. doi: 10.1002/smll.201002074. Epub 2011 Mar 29.

PMID:
21456083
44.

Gene delivery into mesenchymal stem cells: a biomimetic approach using RGD nanoclusters based on poly(amidoamine) dendrimers.

Pandita D, Santos JL, Rodrigues J, Pêgo AP, Granja PL, Tomás H.

Biomacromolecules. 2011 Feb 14;12(2):472-81. doi: 10.1021/bm1012647. Epub 2011 Jan 6.

PMID:
21210673
45.

Non-viral gene delivery to mesenchymal stem cells: methods, strategies and application in bone tissue engineering and regeneration.

Santos JL, Pandita D, Rodrigues J, Pêgo AP, Granja PL, Tomás H.

Curr Gene Ther. 2011 Feb;11(1):46-57. Review.

PMID:
21182464
46.

Chitosan/siRNA nanoparticles biofunctionalize nerve implants and enable neurite outgrowth.

Mittnacht U, Hartmann H, Hein S, Oliveira H, Dong M, Pêgo AP, Kjems J, Howard KA, Schlosshauer B.

Nano Lett. 2010 Oct 13;10(10):3933-9. doi: 10.1021/nl1016909.

PMID:
20795625
47.

Chitosan-based gene delivery vectors targeted to the peripheral nervous system.

Oliveira H, Pires LR, Fernandez R, Martins MC, Simões S, Pêgo AP.

J Biomed Mater Res A. 2010 Dec 1;95(3):801-10. doi: 10.1002/jbm.a.32874.

PMID:
20734332
48.

Protein matrices for improved wound healing: elastase inhibition by a synthetic peptide model.

Vasconcelos A, Pêgo AP, Henriques L, Lamghari M, Cavaco-Paulo A.

Biomacromolecules. 2010 Sep 13;11(9):2213-20. doi: 10.1021/bm100537b.

PMID:
20690591
49.

Receptor-mediated gene delivery using PAMAM dendrimers conjugated with peptides recognized by mesenchymal stem cells.

Santos JL, Pandita D, Rodrigues J, Pêgo AP, Granja PL, Balian G, Tomás H.

Mol Pharm. 2010 Jun 7;7(3):763-74. doi: 10.1021/mp9002877.

PMID:
20230026
50.

Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells.

Santos JL, Oliveira H, Pandita D, Rodrigues J, Pêgo AP, Granja PL, Tomás H.

J Control Release. 2010 May 21;144(1):55-64. doi: 10.1016/j.jconrel.2010.01.034. Epub 2010 Feb 6.

PMID:
20138937

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