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Items: 24


Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses.

Demarta-Gatsi C, Rivkin A, Di Bartolo V, Peronet R, Ding S, Commere PH, Guillonneau F, Bellalou J, Brûlé S, Abou Karam P, Cohen SR, Lagache T, Janse CJ, Regev-Rudzki N, Mécheri S.

Cell Microbiol. 2019 Jul;21(7):e13021. doi: 10.1111/cmi.13021. Epub 2019 Apr 1.


Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite.

Demarta-Gatsi C, Peronet R, Smith L, Thiberge S, Ménard R, Mécheri S.

Sci Rep. 2017 Aug 22;7(1):9129. doi: 10.1038/s41598-017-09684-2.


The antimicrobial molecule trappin-2/elafin has anti-parasitic properties and is protective in vivo in a murine model of cerebral malaria.

Roussilhon C, Bang G, Bastaert F, Solhonne B, Garcia-Verdugo I, Peronet R, Druilhe P, Sakuntabhai A, Mecheri S, Sallenave JM.

Sci Rep. 2017 Feb 9;7:42243. doi: 10.1038/srep42243.


Protection against malaria in mice is induced by blood stage-arresting histamine-releasing factor (HRF)-deficient parasites.

Demarta-Gatsi C, Smith L, Thiberge S, Peronet R, Commere PH, Matondo M, Apetoh L, Bruhns P, Ménard R, Mécheri S.

J Exp Med. 2016 Jul 25;213(8):1419-28. doi: 10.1084/jem.20151976. Epub 2016 Jul 18.


Disruption of Parasite hmgb2 Gene Attenuates Plasmodium berghei ANKA Pathogenicity.

Briquet S, Lawson-Hogban N, Boisson B, Soares MP, Péronet R, Smith L, Ménard R, Huerre M, Mécheri S, Vaquero C.

Infect Immun. 2015 Jul;83(7):2771-84. doi: 10.1128/IAI.03129-14. Epub 2015 Apr 27.


Plasmodium berghei histamine-releasing factor favours liver-stage development via inhibition of IL-6 production and associates with a severe outcome of disease.

Mathieu C, Demarta-Gatsi C, Porcherie A, Brega S, Thiberge S, Ronce K, Smith L, Peronet R, Amino R, Ménard R, Mécheri S.

Cell Microbiol. 2015 Apr;17(4):542-58. doi: 10.1111/cmi.12382. Epub 2014 Nov 22.


Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria.

Porcherie A, Mathieu C, Peronet R, Schneider E, Claver J, Commere PH, Kiefer-Biasizzo H, Karasuyama H, Milon G, Dy M, Kinet JP, Louis J, Blank U, Mécheri S.

J Exp Med. 2011 Oct 24;208(11):2225-36. doi: 10.1084/jem.20110845. Epub 2011 Oct 3.


Anopheles stephensi saliva enhances progression of cerebral malaria in a murine model.

Schneider BS, Mathieu C, Peronet R, Mécheri S.

Vector Borne Zoonotic Dis. 2011 Apr;11(4):423-32. doi: 10.1089/vbz.2010.0120. Epub 2011 Mar 11.


Histamine H(3) receptor-mediated signaling protects mice from cerebral malaria.

Beghdadi W, Porcherie A, Schneider BS, Morisset S, Dubayle D, Peronet R, Dy M, Louis J, Arrang JM, Mécheri S.

PLoS One. 2009 Jun 23;4(6):e6004. doi: 10.1371/journal.pone.0006004.


[Role of histamine and histamine receptors in the pathogenesis of malaria].

Beghdadi W, Porcherie A, Schneider BS, Dubayle D, Peronet R, Huerre M, Watanabe T, Ohtsu H, Louis J, Mécheri S.

Med Sci (Paris). 2009 Apr;25(4):377-81. doi: 10.1051/medsci/2009254377. Review. French.


Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease.

Beghdadi W, Porcherie A, Schneider BS, Dubayle D, Peronet R, Huerre M, Watanabe T, Ohtsu H, Louis J, Mécheri S.

J Exp Med. 2008 Feb 18;205(2):395-408. doi: 10.1084/jem.20071548. Epub 2008 Jan 28.


Mast cell-dependent down-regulation of antigen-specific immune responses by mosquito bites.

Depinay N, Hacini F, Beghdadi W, Peronet R, Mécheri S.

J Immunol. 2006 Apr 1;176(7):4141-6.


Anopheles mosquito bites activate cutaneous mast cells leading to a local inflammatory response and lymph node hyperplasia.

Demeure CE, Brahimi K, Hacini F, Marchand F, Péronet R, Huerre M, St-Mezard P, Nicolas JF, Brey P, Delespesse G, Mécheri S.

J Immunol. 2005 Apr 1;174(7):3932-40.


Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo.

Skokos D, Botros HG, Demeure C, Morin J, Peronet R, Birkenmeier G, Boudaly S, Mécheri S.

J Immunol. 2003 Mar 15;170(6):3037-45.


Nonspecific B and T cell-stimulatory activity mediated by mast cells is associated with exosomes.

Skokos D, Le Panse S, Villa I, Rousselle JC, Peronet R, Namane A, David B, Mécheri S.

Int Arch Allergy Immunol. 2001 Jan-Mar;124(1-3):133-6.


Capacity of mouse mast cells to prime T cells and to induce specific antibody responses in vivo.

Villa I, Skokos D, Tkaczyk C, Peronet R, David B, Huerre M, Mécheri S.

Immunology. 2001 Feb;102(2):165-72.


Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes.

Skokos D, Le Panse S, Villa I, Rousselle JC, Peronet R, David B, Namane A, Mécheri S.

J Immunol. 2001 Jan 15;166(2):868-76.


In vitro and in vivo immunostimulatory potential of bone marrow-derived mast cells on B- and T-lymphocyte activation.

Tkaczyk C, Villa I, Peronet R, David B, Chouaib S, Mécheri S.

J Allergy Clin Immunol. 2000 Jan;105(1 Pt 1):134-42.


Accumulation of major histocompatibility complex class II molecules in mast cell secretory granules and their release upon degranulation.

Raposo G, Tenza D, Mecheri S, Peronet R, Bonnerot C, Desaymard C.

Mol Biol Cell. 1997 Dec;8(12):2631-45.


Mouse bone marrow-derived mast cells and mast cell lines constitutively produce B cell growth and differentiation activities.

Tkaczyk C, Frandji P, Botros HG, Poncet P, Lapeyre J, Peronet R, David B, Mécheri S.

J Immunol. 1996 Aug 15;157(4):1720-8.


Presentation of soluble antigens by mast cells: upregulation by interleukin-4 and granulocyte/macrophage colony-stimulating factor and downregulation by interferon-gamma.

Frandji P, Tkaczyk C, Oskéritzian C, Lapeyre J, Peronet R, David B, Guillet JG, Mécheri S.

Cell Immunol. 1995 Jun;163(1):37-46.


Antigen-dependent stimulation by bone marrow-derived mast cells of MHC class II-restricted T cell hybridoma.

Frandji P, Oskéritzian C, Cacaraci F, Lapeyre J, Peronet R, David B, Guillet JG, Mécheri S.

J Immunol. 1993 Dec 1;151(11):6318-28.


In vivo assessment of mast cell functional alteration induced by L-leucine methyl ester, using the passive cutaneous anaphylaxis technique.

Oskéritzian C, Peronet R, Prouvost-Danon A, David B.

Int Arch Allergy Immunol. 1993;100(1):56-9.


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