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Items: 1 to 50 of 56

1.

Phenotypic Modulation of Cultured Primary Human Aortic Vascular Smooth Muscle Cells by Uremic Serum.

Cazaña-Pérez V, Cidad P, Donate-Correa J, Martín-Núñez E, López-López JR, Pérez-García MT, Giraldez T, Navarro-González JF, Alvarez de la Rosa D.

Front Physiol. 2018 Feb 12;9:89. doi: 10.3389/fphys.2018.00089. eCollection 2018.

2.

Kv channels and vascular smooth muscle cell proliferation.

López-López JR, Cidad P, Pérez-García MT.

Microcirculation. 2018 Jan;25(1). doi: 10.1111/micc.12427. Review.

PMID:
29110368
3.

The secret life of ion channels: Kv1.3 potassium channels and proliferation.

Pérez-García MT, Cidad P, López-López JR.

Am J Physiol Cell Physiol. 2018 Jan 1;314(1):C27-C42. doi: 10.1152/ajpcell.00136.2017. Epub 2017 Sep 20.

PMID:
28931540
4.

Proliferative Role of Kv11 Channels in Murine Arteries.

Barrese V, Cidad P, Yeung SY, López-López JR, McNeish AJ, Ohya S, Pérez-García MT, Greenwood IA.

Front Physiol. 2017 Jul 12;8:500. doi: 10.3389/fphys.2017.00500. eCollection 2017.

5.

Lipin-2 regulates NLRP3 inflammasome by affecting P2X7 receptor activation.

Lordén G, Sanjuán-García I, de Pablo N, Meana C, Alvarez-Miguel I, Pérez-García MT, Pelegrín P, Balsinde J, Balboa MA.

J Exp Med. 2017 Feb;214(2):511-528. doi: 10.1084/jem.20161452. Epub 2016 Dec 28.

6.

Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension.

Álvarez-Miguel I, Cidad P, Pérez-García MT, López-López JR.

J Physiol. 2017 Mar 1;595(5):1497-1513. doi: 10.1113/JP273327. Epub 2016 Dec 29.

7.

Molecular Determinants of Kv1.3 Potassium Channels-induced Proliferation.

Jiménez-Pérez L, Cidad P, Álvarez-Miguel I, Santos-Hipólito A, Torres-Merino R, Alonso E, de la Fuente MÁ, López-López JR, Pérez-García MT.

J Biol Chem. 2016 Feb 12;291(7):3569-80. doi: 10.1074/jbc.M115.678995. Epub 2015 Dec 10.

8.

α5-Integrin-mediated cellular signaling contributes to the myogenic response of cerebral resistance arteries.

Colinas O, Moreno-Domínguez A, Zhu HL, Walsh EJ, Pérez-García MT, Walsh MP, Cole WC.

Biochem Pharmacol. 2015 Oct 1;97(3):281-91. doi: 10.1016/j.bcp.2015.08.088. Epub 2015 Aug 14.

PMID:
26278977
9.

Regulation of smooth muscle dystrophin and synaptopodin 2 expression by actin polymerization and vascular injury.

Turczyńska KM, Swärd K, Hien TT, Wohlfahrt J, Mattisson IY, Ekman M, Nilsson J, Sjögren J, Murugesan V, Hultgårdh-Nilsson A, Cidad P, Hellstrand P, Pérez-García MT, Albinsson S.

Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1489-97. doi: 10.1161/ATVBAHA.114.305065. Epub 2015 Apr 9.

10.

Erratum to: K(+) Channels Expression in Hypertension After Arterial Injury, and Effect of Selective Kv1.3 Blockade with PAP-1 on Intimal Hyperplasia Formation.

Cidad P, Novensà L, Garabito M, Batlle M, Dantas AP, Heras M, López-López JR, Pérez-García MT, Roqué M.

Cardiovasc Drugs Ther. 2015 Apr;29(2):199-200. doi: 10.1007/s10557-015-6578-5. No abstract available.

PMID:
25732511
11.

Tungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle.

Fernández-Mariño AI, Cidad P, Zafra D, Nocito L, Domínguez J, Oliván-Viguera A, Köhler R, López-López JR, Pérez-García MT, Valverde MÁ, Guinovart JJ, Fernández-Fernández JM.

PLoS One. 2015 Feb 6;10(2):e0118148. doi: 10.1371/journal.pone.0118148. eCollection 2015.

12.

K+ channels expression in hypertension after arterial injury, and effect of selective Kv1.3 blockade with PAP-1 on intimal hyperplasia formation.

Cidad P, Novensà L, Garabito M, Batlle M, Dantas AP, Heras M, López-López JR, Pérez-García MT, Roqué M.

Cardiovasc Drugs Ther. 2014 Dec;28(6):501-11. doi: 10.1007/s10557-014-6554-5. Erratum in: Cardiovasc Drugs Ther. 2015 Apr;29(2):199-200.

PMID:
25348824
13.

Kv1.3 channels modulate human vascular smooth muscle cells proliferation independently of mTOR signaling pathway.

Cidad P, Miguel-Velado E, Ruiz-McDavitt C, Alonso E, Jiménez-Pérez L, Asuaje A, Carmona Y, García-Arribas D, López J, Marroquín Y, Fernández M, Roqué M, Pérez-García MT, López-López JR.

Pflugers Arch. 2015 Aug;467(8):1711-22. doi: 10.1007/s00424-014-1607-y. Epub 2014 Sep 12.

PMID:
25208915
14.

Cinnamaldehyde inhibits L-type calcium channels in mouse ventricular cardiomyocytes and vascular smooth muscle cells.

Alvarez-Collazo J, Alonso-Carbajo L, López-Medina AI, Alpizar YA, Tajada S, Nilius B, Voets T, López-López JR, Talavera K, Pérez-García MT, Alvarez JL.

Pflugers Arch. 2014 Nov;466(11):2089-99. doi: 10.1007/s00424-014-1472-8. Epub 2014 Feb 25.

PMID:
24563220
15.

TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins.

Meseguer V, Alpizar YA, Luis E, Tajada S, Denlinger B, Fajardo O, Manenschijn JA, Fernández-Peña C, Talavera A, Kichko T, Navia B, Sánchez A, Señarís R, Reeh P, Pérez-García MT, López-López JR, Voets T, Belmonte C, Talavera K, Viana F.

Nat Commun. 2014;5:3125. doi: 10.1038/ncomms4125.

16.

Down-regulation of CaV1.2 channels during hypertension: how fewer CaV1.2 channels allow more Ca(2+) into hypertensive arterial smooth muscle.

Tajada S, Cidad P, Colinas O, Santana LF, López-López JR, Pérez-García MT.

J Physiol. 2013 Dec 15;591(24):6175-91. doi: 10.1113/jphysiol.2013.265751. Epub 2013 Oct 28.

17.

High blood pressure associates with the remodelling of inward rectifier K+ channels in mice mesenteric vascular smooth muscle cells.

Tajada S, Cidad P, Moreno-Domínguez A, Pérez-García MT, López-López JR.

J Physiol. 2012 Dec 1;590(23):6075-91. doi: 10.1113/jphysiol.2012.236190. Epub 2012 Sep 10.

18.

Kv1.3 channels can modulate cell proliferation during phenotypic switch by an ion-flux independent mechanism.

Cidad P, Jiménez-Pérez L, García-Arribas D, Miguel-Velado E, Tajada S, Ruiz-McDavitt C, López-López JR, Pérez-García MT.

Arterioscler Thromb Vasc Biol. 2012 May;32(5):1299-307. doi: 10.1161/ATVBAHA.111.242727. Epub 2012 Mar 1.

19.

Characterization of ion channels involved in the proliferative response of femoral artery smooth muscle cells.

Cidad P, Moreno-Domínguez A, Novensá L, Roqué M, Barquín L, Heras M, Pérez-García MT, López-López JR.

Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1203-11. doi: 10.1161/ATVBAHA.110.205187. Epub 2010 Mar 18.

20.

Cell cycle-dependent expression of Kv3.4 channels modulates proliferation of human uterine artery smooth muscle cells.

Miguel-Velado E, Pérez-Carretero FD, Colinas O, Cidad P, Heras M, López-López JR, Pérez-García MT.

Cardiovasc Res. 2010 Jun 1;86(3):383-91. doi: 10.1093/cvr/cvq011. Epub 2010 Jan 21.

PMID:
20093253
21.

Oxygen-sensitive potassium channels in chemoreceptor cell physiology: making a virtue of necessity.

Gonzalez C, Vaquero LM, López-López JR, Pérez-García MT.

Ann N Y Acad Sci. 2009 Oct;1177:82-8. doi: 10.1111/j.1749-6632.2009.05037.x. Review.

PMID:
19845610
22.

DPPX modifies TEA sensitivity of the Kv4 channels in rabbit carotid body chemoreceptor cells.

Colinas O, Pérez-Carretero FD, Alonso E, López-López JR, Pérez-García MT.

Adv Exp Med Biol. 2009;648:73-82. doi: 10.1007/978-90-481-2259-2_8.

PMID:
19536467
23.

De novo expression of Kv6.3 contributes to changes in vascular smooth muscle cell excitability in a hypertensive mice strain.

Moreno-Domínguez A, Cidad P, Miguel-Velado E, López-López JR, Pérez-García MT.

J Physiol. 2009 Feb 1;587(3):625-40. doi: 10.1113/jphysiol.2008.165217. Epub 2008 Dec 15.

24.

A role for DPPX modulating external TEA sensitivity of Kv4 channels.

Colinas O, Pérez-Carretero FD, López-López JR, Pérez-García MT.

J Gen Physiol. 2008 May;131(5):455-71. doi: 10.1085/jgp.200709912. Epub 2008 Apr 14.

25.

An ASIC channel for acid chemotransduction.

López-López JR, Pérez-García MT.

Circ Res. 2007 Nov 9;101(10):965-7. No abstract available.

26.

Oxygen sensitive Kv channels in the carotid body.

López-López JR, Pérez-García MT.

Respir Physiol Neurobiol. 2007 Jul 1;157(1):65-74. Epub 2007 Mar 4. Review.

PMID:
17442633
27.

Differential modulation of Kv4.2 and Kv4.3 channels by calmodulin-dependent protein kinase II in rat cardiac myocytes.

Colinas O, Gallego M, Setién R, López-López JR, Pérez-García MT, Casis O.

Am J Physiol Heart Circ Physiol. 2006 Oct;291(4):H1978-87. Epub 2006 Apr 28.

28.

Contribution of Kv channels to phenotypic remodeling of human uterine artery smooth muscle cells.

Miguel-Velado E, Moreno-Domínguez A, Colinas O, Cidad P, Heras M, Pérez-García MT, López-López JR.

Circ Res. 2005 Dec 9;97(12):1280-7. Epub 2005 Nov 3.

29.

Down regulation of Kv3.4 channels by chronic hypoxia increases acute oxygen sensitivity in rabbit carotid body.

Kääb S, Miguel-Velado E, López-López JR, Pérez-García MT.

J Physiol. 2005 Jul 15;566(Pt 2):395-408. Epub 2005 May 12.

30.

Comparative gene expression profile of mouse carotid body and adrenal medulla under physiological hypoxia.

Ganfornina MD, Pérez-García MT, Gutiérrez G, Miguel-Velado E, López-López JR, Marín A, Sánchez D, González C.

J Physiol. 2005 Jul 15;566(Pt 2):491-503. Epub 2005 May 12.

31.

Characterization of the Kv channels of mouse carotid body chemoreceptor cells and their role in oxygen sensing.

Pérez-García MT, Colinas O, Miguel-Velado E, Moreno-Domínguez A, López-López JR.

J Physiol. 2004 Jun 1;557(Pt 2):457-71. Epub 2004 Mar 19.

32.

Ventilatory responses and carotid body function in adult rats perinatally exposed to hyperoxia.

Prieto-Lloret J, Caceres AI, Obeso A, Rocher A, Rigual R, Agapito MT, Bustamante R, Castañeda J, Perez-Garcia MT, Lopez-Lopez JR, Gonzalez C.

J Physiol. 2004 Jan 1;554(Pt 1):126-44.

33.

Functional identification of Kvalpha subunits contributing to the O2-sensitive K+ current in rabbit carotid body chemoreceptor cells.

López-López JR, Pérez-García MT, Sanz-Alfayate G, Obeso A, Gonzalez C.

Adv Exp Med Biol. 2003;536:33-9. No abstract available.

PMID:
14635646
34.

Molecular identification of Kvalpha subunits that contribute to the oxygen-sensitive K+ current of chemoreceptor cells of the rabbit carotid body.

Sanchez D, López-López JR, Pérez-García MT, Sanz-Alfayate G, Obeso A, Ganfornina MD, Gonzalez C.

J Physiol. 2002 Jul 15;542(Pt 2):369-82.

35.

O(2) modulates large-conductance Ca(2+)-dependent K(+) channels of rat chemoreceptor cells by a membrane-restricted and CO-sensitive mechanism.

Riesco-Fagundo AM, Pérez-García MT, González C, López-López JR.

Circ Res. 2001 Aug 31;89(5):430-6.

36.

Viral gene transfer of dominant-negative Kv4 construct suppresses an O2-sensitive K+ current in chemoreceptor cells.

Pérez-García MT, López-López JR, Riesco AM, Hoppe UC, Marbán E, Gonzalez C, Johns DC.

J Neurosci. 2000 Aug 1;20(15):5689-95.

37.

Are Kv channels the essence of O2 sensing?

Pérez-García MT, López-López JR.

Circ Res. 2000 Mar 17;86(5):490-1. Review. No abstract available.

38.

Kvbeta1.2 subunit coexpression in HEK293 cells confers O2 sensitivity to kv4.2 but not to Shaker channels.

Pérez-García MT, López-López JR, González C.

J Gen Physiol. 1999 Jun;113(6):897-907.

39.

Effects of almitrine bismesylate on the ionic currents of chemoreceptor cells from the carotid body.

López-López JR, Pérez-García MT, Canet E, Gonzalez C.

Mol Pharmacol. 1998 Feb;53(2):330-9.

40.

Mechanisms of sodium/calcium selectivity in sodium channels probed by cysteine mutagenesis and sulfhydryl modification.

Pérez-García MT, Chiamvimonvat N, Ranjan R, Balser JR, Tomaselli GF, Marban E.

Biophys J. 1997 Mar;72(3):989-96.

41.

Properties of ionic currents from isolated adult rat carotid body chemoreceptor cells: effect of hypoxia.

López-López JR, González C, Pérez-García MT.

J Physiol. 1997 Mar 1;499 ( Pt 2):429-41.

42.

Mechanisms of alpha2-adrenoceptor-mediated inhibition in rabbit carotid body.

Almaraz L, Pérez-García MT, Gómez-Nino A, González C.

Am J Physiol. 1997 Feb;272(2 Pt 1):C628-37.

PMID:
9124307
43.

External pore residue mediates slow inactivation in mu 1 rat skeletal muscle sodium channels.

Balser JR, Nuss HB, Chiamvimonvat N, Pérez-García MT, Marban E, Tomaselli GF.

J Physiol. 1996 Jul 15;494 ( Pt 2):431-42.

44.

Depth asymmetries of the pore-lining segments of the Na+ channel revealed by cysteine mutagenesis.

Chiamvimonvat N, Pérez-García MT, Ranjan R, Marban E, Tomaselli GF.

Neuron. 1996 May;16(5):1037-47.

46.

Control of ion flux and selectivity by negatively charged residues in the outer mouth of rat sodium channels.

Chiamvimonvat N, Pérez-García MT, Tomaselli GF, Marban E.

J Physiol. 1996 Feb 15;491 ( Pt 1):51-9.

47.

Structure of the sodium channel pore revealed by serial cysteine mutagenesis.

Pérez-García MT, Chiamvimonvat N, Marban E, Tomaselli GF.

Proc Natl Acad Sci U S A. 1996 Jan 9;93(1):300-4.

48.

Cellular mechanisms of oxygen chemoreception in the carotid body.

Gonzalez C, Lopez-Lopez JR, Obeso A, Perez-Garcia MT, Rocher A.

Respir Physiol. 1995 Dec;102(2-3):137-47. Review.

PMID:
8904006
49.
50.

A mutation in the pore of the sodium channel alters gating.

Tomaselli GF, Chiamvimonvat N, Nuss HB, Balser JR, Pérez-García MT, Xu RH, Orias DW, Backx PH, Marban E.

Biophys J. 1995 May;68(5):1814-27.

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