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Items: 26

1.

The SRC Inhibitor Dasatinib Induces Stem Cell-Like Properties in Head and Neck Cancer Cells that are Effectively Counteracted by the Mithralog EC-8042.

Hermida-Prado F, Villaronga MÁ, Granda-Díaz R, Del-Río-Ibisate N, Santos L, Hermosilla MA, Oro P, Allonca E, Agorreta J, Garmendia I, Tornín J, Perez-Escuredo J, Fuente R, Montuenga LM, Morís F, Rodrigo JP, Rodríguez R, García-Pedrero JM.

J Clin Med. 2019 Aug 2;8(8). pii: E1157. doi: 10.3390/jcm8081157.

2.

Transcriptional Reprogramming and Inhibition of Tumor-propagating Stem-like Cells by EC-8042 in ERG-positive Prostate Cancer.

Shinde D, Albino D, Zoma M, Mutti A, Mapelli SN, Civenni G, Kokanovic A, Merulla J, Perez-Escuredo J, Costales P, Morìs F, Catapano CV, Carbone GM.

Eur Urol Oncol. 2019 Jul;2(4):415-424. doi: 10.1016/j.euo.2018.08.024. Epub 2018 Sep 24.

PMID:
31277777
3.

The multikinase inhibitor EC-70124 synergistically increased the antitumor activity of doxorubicin in sarcomas.

Estupiñan O, Santos L, Rodriguez A, Fernandez-Nevado L, Costales P, Perez-Escuredo J, Hermosilla MA, Oro P, Rey V, Tornin J, Allonca E, Fernandez-Garcia MT, Alvarez-Fernandez C, Braña A, Astudillo A, Menendez ST, Moris F, Rodriguez R.

Int J Cancer. 2019 Jul 1;145(1):254-266. doi: 10.1002/ijc.32081. Epub 2019 Jan 14.

PMID:
30575954
4.

Inhibition of FLT3 and PIM Kinases by EC-70124 Exerts Potent Activity in Preclinical Models of Acute Myeloid Leukemia.

Puente-Moncada N, Costales P, Antolín I, Núñez LE, Oro P, Hermosilla MA, Pérez-Escuredo J, Ríos-Lombardía N, Sanchez-Sanchez AM, Luño E, Rodríguez C, Martín V, Morís F.

Mol Cancer Ther. 2018 Mar;17(3):614-624. doi: 10.1158/1535-7163.MCT-17-0530. Epub 2018 Jan 16.

5.

Genomic profiling of intestinal-type sinonasal adenocarcinoma reveals subgroups of patients with distinct clinical outcomes.

López-Hernández A, Pérez-Escuredo J, Vivanco B, García-Inclán C, Potes-Ares S, Cabal VN, Riobello C, Costales M, López F, Llorente JL, Hermsen MA.

Head Neck. 2018 Feb;40(2):259-273. doi: 10.1002/hed.24941. Epub 2017 Sep 30.

PMID:
28963820
6.

Recurrent DNA copy number alterations in intestinal-type sinonasal adenocarcinoma.

Perez-Escuredo J, Lopez-Hernandez A, Costales M, Lopez F, Ares SP, Vivanco B, Llorente JL, Hermsen MA.

Rhinology. 2016 Sep;54(3):278-86. doi: 10.4193/Rhin15.382.

PMID:
27107016
7.

Monocarboxylate transporters in the brain and in cancer.

Pérez-Escuredo J, Van Hée VF, Sboarina M, Falces J, Payen VL, Pellerin L, Sonveaux P.

Biochim Biophys Acta. 2016 Oct;1863(10):2481-97. doi: 10.1016/j.bbamcr.2016.03.013. Epub 2016 Mar 16. Review.

8.

Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.

Pérez-Escuredo J, Dadhich RK, Dhup S, Cacace A, Van Hée VF, De Saedeleer CJ, Sboarina M, Rodriguez F, Fontenille MJ, Brisson L, Porporato PE, Sonveaux P.

Cell Cycle. 2016;15(1):72-83. doi: 10.1080/15384101.2015.1120930.

9.

Lactate does not activate NF-κB in oxidative tumor cells.

Van Hée VF, Pérez-Escuredo J, Cacace A, Copetti T, Sonveaux P.

Front Pharmacol. 2015 Oct 13;6:228. doi: 10.3389/fphar.2015.00228. eCollection 2015.

10.

A mitochondrial switch promotes tumor metastasis.

Porporato PE, Payen VL, Pérez-Escuredo J, De Saedeleer CJ, Danhier P, Copetti T, Dhup S, Tardy M, Vazeille T, Bouzin C, Feron O, Michiels C, Gallez B, Sonveaux P.

Cell Rep. 2014 Aug 7;8(3):754-66. doi: 10.1016/j.celrep.2014.06.043. Epub 2014 Jul 24.

11.

Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration.

De Saedeleer CJ, Porporato PE, Copetti T, Pérez-Escuredo J, Payen VL, Brisson L, Feron O, Sonveaux P.

Oncogene. 2014 Jul 31;33(31):4060-8. doi: 10.1038/onc.2013.454. Epub 2013 Oct 28.

PMID:
24166504
12.

Localization of centromeric breaks in head and neck squamous cell carcinoma.

Martínez JG, Pérez-Escuredo J, Llorente JL, Suárez C, Hermsen MA.

Cancer Genet. 2012 Dec;205(12):622-9. doi: 10.1016/j.cancergen.2012.10.002. Epub 2012 Nov 17.

PMID:
23164608
13.

Intestinal-type sinonasal adenocarcinomas. Immunohistochemical profile of 66 cases.

Vivanco Allende B, Perez-Escuredo J, Fuentes Martínez N, Fresno Forcelledo MF, Llorente Pendás JL, Hermsen M.

Acta Otorrinolaringol Esp. 2013 Mar-Apr;64(2):115-23. doi: 10.1016/j.otorri.2012.09.002. Epub 2012 Oct 31. English, Spanish.

14.

EGFR status and KRAS/BRAF mutations in intestinal-type sinonasal adenocarcinomas.

García-Inclán C, López F, Pérez-Escuredo J, Cuesta-Albalad MP, Vivanco B, Centeno I, Balbín M, Suárez C, Llorente JL, Hermsen MA.

Cell Oncol (Dordr). 2012 Dec;35(6):443-50. doi: 10.1007/s13402-012-0103-7. Epub 2012 Oct 11.

PMID:
23055340
15.

Hypomethylation of LINE-1, and not centromeric SAT-α, is associated with centromeric instability in head and neck squamous cell carcinoma.

Martínez JG, Pérez-Escuredo J, Castro-Santos P, Marcos CA, Pendás JL, Fraga MF, Hermsen MA.

Cell Oncol (Dordr). 2012 Aug;35(4):259-67. doi: 10.1007/s13402-012-0085-5. Epub 2012 Jun 21.

PMID:
22718136
16.

Molecular characterisation of sinonasal carcinomas and their clinical implications.

López F, Llorente JL, Costales M, García-Inclán C, Pérez-Escuredo J, Alvarez-Marcos C, Hermsen M, Suárez C.

Acta Otorrinolaringol Esp. 2013 Jul-Aug;64(4):289-96. doi: 10.1016/j.otorri.2012.03.002. Epub 2012 May 21. Review. English, Spanish.

17.

Wood dust-related mutational profile of TP53 in intestinal-type sinonasal adenocarcinoma.

Pérez-Escuredo J, Martínez JG, Vivanco B, Marcos CÁ, Suárez C, Llorente JL, Hermsen MA.

Hum Pathol. 2012 Nov;43(11):1894-901. doi: 10.1016/j.humpath.2012.01.016. Epub 2012 May 8.

PMID:
22575263
18.

KRAS and BRAF mutations in sinonasal cancer.

López F, García Inclán C, Pérez-Escuredo J, Alvarez Marcos C, Scola B, Suárez C, Llorente JL, Hermsen MA.

Oral Oncol. 2012 Aug;48(8):692-7. doi: 10.1016/j.oraloncology.2012.02.018. Epub 2012 Mar 27.

PMID:
22459936
19.

Wnt-pathway activation in intestinal-type sinonasal adenocarcinoma.

Díaz-Molina JP, Llorente JL, Vivanco B, Martínez-Camblor P, Fresno MF, Pérez-Escuredo J, Álvarez-Marcos C, Hermsen MA.

Rhinology. 2011 Dec;49(5):593-9. doi: 10.4193/Rhino11.037.

PMID:
22125792
20.

[Analysis of microsatellite instability in laryngeal squamous cell carcinoma].

García Martínez J, Pérez-Escuredo J, García-Carracedo D, Alonso-Guervós M, Suárez-Nieto C, Llorente-Pendás JL, Alvarez-Marcos C, Hermsen M.

Acta Otorrinolaringol Esp. 2012 Mar-Apr;63(2):79-84. doi: 10.1016/j.otorri.2011.07.005. Epub 2011 Nov 17. Spanish. Erratum in: Acta Otorrinolaringol Esp. 2012 May-Jun;63(3):246-7.

21.

Benign lesions in mucosa adjacent to intestinal-type sinonasal adenocarcinoma.

Vivanco B, Llorente JL, Perez-Escuredo J, Alvarez Marcos C, Fresno MF, Hermsen MA.

Patholog Res Int. 2011 Apr 20;2011:230147. doi: 10.4061/2011/230147.

22.

Establishment and genetic characterization of an immortal tumor cell line derived from intestinal-type sinonasal adenocarcinoma.

Pérez-Escuredo J, García Martínez J, García-Inclán C, Vivanco B, Costales M, Álvarez Marcos C, Llorente JL, Hermsen MA.

Cell Oncol (Dordr). 2011 Feb;34(1):23-31. doi: 10.1007/s13402-010-0002-8. Epub 2011 Jan 18.

PMID:
21360264
23.

Microsatellite instability analysis of sinonasal carcinomas.

Martínez JG, Pérez-Escuredo J, López F, Suárez C, Alvarez-Marcos C, Llorente JL, Hermsen MA.

Otolaryngol Head Neck Surg. 2009 Jan;140(1):55-60. doi: 10.1016/j.otohns.2008.10.038.

PMID:
19130962
24.

Genome-wide analysis of genetic changes in intestinal-type sinonasal adenocarcinoma.

Hermsen MA, Llorente JL, Pérez-Escuredo J, López F, Ylstra B, Alvarez-Marcos C, Suárez C.

Head Neck. 2009 Mar;31(3):290-7. doi: 10.1002/hed.20973.

PMID:
19073009
25.

Genetic and clinical aspects of wood dust related intestinal-type sinonasal adenocarcinoma: a review.

Llorente JL, Pérez-Escuredo J, Alvarez-Marcos C, Suárez C, Hermsen M.

Eur Arch Otorhinolaryngol. 2009 Jan;266(1):1-7. doi: 10.1007/s00405-008-0749-y. Epub 2008 Jun 17. Review.

PMID:
18560862
26.

[Viral infection of herpes simplex, Epstein-Barr, varicela zoster, human papilloma, cytomegalovirus, or adenovirus are not related to sinonasal adenocarcinomas].

Pérez Escuredo J, Llorente JL, Melón S, de Oña M, García Martínez J, Alvarez Marcos C, Hermsen M.

Acta Otorrinolaringol Esp. 2007 Aug-Sep;58(7):311-5. Spanish.

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