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Best matches for Pérez de Castro I[au]:

Editorial: Aurora Kinases: Classical Mitotic Roles, Non-Canonical Functions and Translational Views. Pérez de Castro I et al. Front Oncol. (2017)

Aurora kinase A inhibitors: promising agents in antitumoral therapy. Malumbres M et al. Expert Opin Ther Targets. (2014)

Aurora A drives early signalling and vesicle dynamics during T-cell activation. Blas-Rus N et al. Nat Commun. (2016)

Search results

Items: 50

1.

Editorial: Aurora Kinases: Classical Mitotic Roles, Non-Canonical Functions and Translational Views.

Pérez de Castro I, Carmena M, Prigent C, Glover DM.

Front Oncol. 2017 Mar 22;7:48. doi: 10.3389/fonc.2017.00048. eCollection 2017. No abstract available.

2.

Aurora A drives early signalling and vesicle dynamics during T-cell activation.

Blas-Rus N, Bustos-Morán E, Pérez de Castro I, de Cárcer G, Borroto A, Camafeita E, Jorge I, Vázquez J, Alarcón B, Malumbres M, Martín-Cófreces NB, Sánchez-Madrid F.

Nat Commun. 2016 Apr 19;7:11389. doi: 10.1038/ncomms11389.

3.

Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression.

Bueno MJ, Pérez de Castro I, Gómez de Cedrón M, Santos J, Calin GA, Cigudosa JC, Croce CM, Fernández-Piqueras J, Malumbres M.

Cancer Cell. 2016 Apr 11;29(4):607-608. doi: 10.1016/j.ccell.2016.03.013. No abstract available.

4.

Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development.

González-Loyola A, Fernández-Miranda G, Trakala M, Partida D, Samejima K, Ogawa H, Cañamero M, de Martino A, Martínez-Ramírez Á, de Cárcer G, Pérez de Castro I, Earnshaw WC, Malumbres M.

Mol Cell Biol. 2015 Oct;35(20):3566-78. doi: 10.1128/MCB.01286-14. Epub 2015 Aug 3.

5.

Phosphorylation of targeting protein for Xenopus kinesin-like protein 2 (TPX2) at threonine 72 in spindle assembly.

Shim SY, Perez de Castro I, Neumayer G, Wang J, Park SK, Sanada K, Nguyen MD.

J Biol Chem. 2015 Apr 3;290(14):9122-34. doi: 10.1074/jbc.M114.591545. Epub 2015 Feb 16.

6.

Aurora kinase A inhibitors: promising agents in antitumoral therapy.

Malumbres M, Pérez de Castro I.

Expert Opin Ther Targets. 2014 Dec;18(12):1377-93. doi: 10.1517/14728222.2014.956085. Epub 2014 Sep 9. Review.

PMID:
25200357
7.

Requirements for Aurora-A in tissue regeneration and tumor development in adult mammals.

Pérez de Castro I, Aguirre-Portolés C, Fernández-Miranda G, Cañamero M, Cowley DO, Van Dyke T, Malumbres M.

Cancer Res. 2013 Nov 15;73(22):6804-15. doi: 10.1158/0008-5472.CAN-13-0586.

8.

Mitotic Stress and Chromosomal Instability in Cancer: The Case for TPX2.

Pérez de Castro I, Malumbres M.

Genes Cancer. 2012 Nov;3(11-12):721-30. doi: 10.1177/1947601912473306.

9.

Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1).

Trakala M, Fernández-Miranda G, Pérez de Castro I, Heeschen C, Malumbres M.

Cell Cycle. 2013 Apr 1;12(7):1030-41. doi: 10.4161/cc.24004. Epub 2013 Feb 21.

10.

Tpx2 controls spindle integrity, genome stability, and tumor development.

Aguirre-Portolés C, Bird AW, Hyman A, Cañamero M, Pérez de Castro I, Malumbres M.

Cancer Res. 2012 Mar 15;72(6):1518-28. doi: 10.1158/0008-5472.CAN-11-1971. Epub 2012 Jan 20.

11.

Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development.

Fernández-Miranda G, Trakala M, Martín J, Escobar B, González A, Ghyselinck NB, Ortega S, Cañamero M, Pérez de Castro I, Malumbres M.

Development. 2011 Jul;138(13):2661-72. doi: 10.1242/dev.066381. Epub 2011 May 25.

12.

Combinatorial effects of microRNAs to suppress the Myc oncogenic pathway.

Bueno MJ, Gómez de Cedrón M, Gómez-López G, Pérez de Castro I, Di Lisio L, Montes-Moreno S, Martínez N, Guerrero M, Sánchez-Martínez R, Santos J, Pisano DG, Piris MA, Fernández-Piqueras J, Malumbres M.

Blood. 2011 Jun 9;117(23):6255-66. doi: 10.1182/blood-2010-10-315432. Epub 2011 Apr 8.

13.

A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis.

Pérez de Castro I, Aguirre-Portolés C, Martin B, Fernández-Miranda G, Klotzbucher A, Kubbutat MH, Megías D, Arlot-Bonnemains Y, Malumbres M.

Front Oncol. 2011 Dec 14;1:50. doi: 10.3389/fonc.2011.00050. eCollection 2011.

14.

SUMOylation modulates the function of Aurora-B kinase.

Fernández-Miranda G, Pérez de Castro I, Carmena M, Aguirre-Portolés C, Ruchaud S, Fant X, Montoya G, Earnshaw WC, Malumbres M.

J Cell Sci. 2010 Aug 15;123(Pt 16):2823-33. doi: 10.1242/jcs.065565. Epub 2010 Jul 27.

15.

Control of cell proliferation pathways by microRNAs.

Bueno MJ, Pérez de Castro I, Malumbres M.

Cell Cycle. 2008 Oct;7(20):3143-8. Epub 2008 Oct 20. Review.

PMID:
18843198
16.

Emerging cancer therapeutic opportunities by inhibiting mitotic kinases.

Pérez de Castro I, de Cárcer G, Montoya G, Malumbres M.

Curr Opin Pharmacol. 2008 Aug;8(4):375-83. doi: 10.1016/j.coph.2008.06.013. Epub 2008 Jul 30. Review.

PMID:
18644252
17.

Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression.

Bueno MJ, Pérez de Castro I, Gómez de Cedrón M, Santos J, Calin GA, Cigudosa JC, Croce CM, Fernández-Piqueras J, Malumbres M.

Cancer Cell. 2008 Jun;13(6):496-506. doi: 10.1016/j.ccr.2008.04.018. Erratum in: Cancer Cell. 2016 Apr 11;29(4):607-8.

18.

Targeting cell cycle kinases for cancer therapy.

de Cárcer G, Pérez de Castro I, Malumbres M.

Curr Med Chem. 2007;14(9):969-85. Review.

PMID:
17439397
19.

A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy.

Pérez de Castro I, de Cárcer G, Malumbres M.

Carcinogenesis. 2007 May;28(5):899-912. Epub 2007 Jan 27. Review.

PMID:
17259655
20.

PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis.

Bivona TG, Quatela SE, Bodemann BO, Ahearn IM, Soskis MJ, Mor A, Miura J, Wiener HH, Wright L, Saba SG, Yim D, Fein A, Pérez de Castro I, Li C, Thompson CB, Cox AD, Philips MR.

Mol Cell. 2006 Feb 17;21(4):481-93.

21.

Mouse p10, an alternative spliced form of p15INK4b, inhibits cell cycle progression and malignant transformation.

Pérez de Castro I, Benet M, Jiménez M, Alzabin S, Malumbres M, Pellicer A.

Cancer Res. 2005 Apr 15;65(8):3249-56.

22.

The Rgr oncogene induces tumorigenesis in transgenic mice.

Jiménez M, Pérez de Castro I, Benet M, García JF, Inghirami G, Pellicer A.

Cancer Res. 2004 Sep 1;64(17):6041-9.

23.
24.

Systemic tumor targeting and killing by Sindbis viral vectors.

Tseng JC, Levin B, Hurtado A, Yee H, Perez de Castro I, Jimenez M, Shamamian P, Jin R, Novick RP, Pellicer A, Meruelo D.

Nat Biotechnol. 2004 Jan;22(1):70-7. Epub 2003 Nov 30.

PMID:
14647305
25.

NF1 modulates the effects of Ras oncogenes: evidence of other NF1 function besides its GAP activity.

Corral T, Jiménez M, Hernández-Muñoz I, Pérez de Castro I, Pellicer A.

J Cell Physiol. 2003 Nov;197(2):214-24.

PMID:
14502561
26.

Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1.

Bivona TG, Pérez De Castro I, Ahearn IM, Grana TM, Chiu VK, Lockyer PJ, Cullen PJ, Pellicer A, Cox AD, Philips MR.

Nature. 2003 Aug 7;424(6949):694-8. Epub 2003 Jun 29.

PMID:
12845332
27.

Mice deficient for N-ras: impaired antiviral immune response and T-cell function.

Pérez de Castro I, Diaz R, Malumbres M, Hernández MI, Jagirdar J, Jiménez M, Ahn D, Pellicer A.

Cancer Res. 2003 Apr 1;63(7):1615-22.

28.

Genetics of pathological gambling.

Ibáñez A, Blanco C, Perez de Castro I, Fernandez-Piqueras J, Sáiz-Ruiz J.

J Gambl Stud. 2003 Spring;19(1):11-22. Review.

PMID:
12635538
29.

Concurrent positive association between pathological gambling and functional DNA polymorphisms at the MAO-A and the 5-HT transporter genes.

Pérez de Castro I, Ibáñez A, Saiz-Ruiz J, Fernández-Piqueras J.

Mol Psychiatry. 2002;7(9):927-8. No abstract available.

30.

The N-ras proto-oncogene can suppress the malignant phenotype in the presence or absence of its oncogene.

Diaz R, Ahn D, Lopez-Barcons L, Malumbres M, Perez de Castro I, Lue J, Ferrer-Miralles N, Mangues R, Tsong J, Garcia R, Perez-Soler R, Pellicer A.

Cancer Res. 2002 Aug 1;62(15):4514-8.

31.

Psychiatric comorbidity in pathological gamblers seeking treatment.

Ibáñez A, Blanco C, Donahue E, Lesieur HR, Pérez de Castro I, Fernández-Piqueras J, Sáiz-Ruiz J.

Am J Psychiatry. 2001 Oct;158(10):1733-5.

PMID:
11579014
32.

Characterization of the murine p19(ARF) promoter CpG island and its methylation pattern in primary lymphomas.

Meléndez B, Malumbres M, Pérez de Castro I, Santos J, Pellicer A, Fernández-Piqueras J.

Carcinogenesis. 2000 Apr;21(4):817-21.

PMID:
10753221
33.

Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b).

Malumbres M, Pérez De Castro I, Hernández MI, Jiménez M, Corral T, Pellicer A.

Mol Cell Biol. 2000 Apr;20(8):2915-25.

34.

Pathological gambling and DNA polymorphic markers at MAO-A and MAO-B genes.

Ibañez A, Perez de Castro I, Fernandez-Piqueras J, Blanco C, Saiz-Ruiz J.

Mol Psychiatry. 2000 Jan;5(1):105-9.

PMID:
10673777
35.

Genetic contribution to pathological gambling: possible association between a functional DNA polymorphism at the serotonin transporter gene (5-HTT) and affected men.

Pérez de Castro I, Ibáñez A, Saiz-Ruiz J, Fernández-Piqueras J.

Pharmacogenetics. 1999 Jun;9(3):397-400. No abstract available.

PMID:
10471073
36.

Cooperative alterations of Rb pathway regulators in mouse primary T cell lymphomas.

Pérez de Castro IP, Malumbres M, Santos J, Pellicer A, Fernández-Piqueras J.

Carcinogenesis. 1999 Sep;20(9):1675-82.

PMID:
10469610
37.

Hypermethylation of the cell cycle inhibitor p15INK4b 3'-untranslated region interferes with its transcriptional regulation in primary lymphomas.

Malumbres M, Pérez de Castro I, Santos J, Fernández Piqueras J, Pellicer A.

Oncogene. 1999 Jan 14;18(2):385-96.

38.

A new candidate site for a tumor suppressor gene involved in mouse thymic lymphomagenesis is located on the distal part of chromosome 4.

Santos J, Herranz M, Pérez de Castro I, Pellicer A, Fernández-Piqueras J.

Oncogene. 1998 Aug 20;17(7):925-9.

39.

An AC-repeat adjacent to mouse Cdkn2B allows the detection of specific allelic losses in the p15INK4b and p16INK4a tumor suppressor genes.

Malumbres M, Pérez de Castro I, Santos J, Pérez-Ollé R, Fernández-Piqueras J, Pellicer A.

Mamm Genome. 1998 Mar;9(3):183-5.

PMID:
9501299
40.

Genetic association study between pathological gambling and a functional DNA polymorphism at the D4 receptor gene.

Pérez de Castro I, Ibáñez A, Torres P, Sáiz-Ruiz J, Fernández-Piqueras J.

Pharmacogenetics. 1997 Oct;7(5):345-8.

PMID:
9352568
41.

Frequent allelic losses of 9p21 markers and low incidence of mutations at p16(CDKN2) gene in non-Hodgkin lymphomas of B-cell lineage.

Fernández-Piqueras J, Santos J, Pérez de Castro I, Meléndez B, Martínez B, Robledo M, Rivas C, Benítez J.

Cancer Genet Cytogenet. 1997 Oct 1;98(1):63-8.

PMID:
9309120
42.

Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas.

Malumbres M, Pérez de Castro I, Santos J, Meléndez B, Mangues R, Serrano M, Pellicer A, Fernández-Piqueras J.

Oncogene. 1997 Mar 20;14(11):1361-70.

43.

Instability of the D4Mit12 microsatellite marker in C57BL/6J x BALB/cJF1 hybrid mice is independent of the tumor phenotype.

Herranz M, Santos J, Pérez de Castro I, Meléndez B, Fernández-Piqueras J.

Cytogenet Cell Genet. 1997;78(3-4):221-3.

PMID:
9465892
44.
45.

No association between particular DRD3 and DAT gene polymorphisms and manic-depressive illness in a Spanish sample.

Gómez-Casero E, Pérez de Castro I, Sáiz-Ruiz J, Llinares C, Fernández-Piqueras J.

Psychiatr Genet. 1996 Winter;6(4):209-12.

PMID:
9149327
46.

Familial cosegregation of manic-depressive illness and a form of hereditary cerebellar ataxia.

Fernández Piqueras J, Santos J, Visedo G, Pérez de Castro I, Puertollano R, Montejo J, Ramo Tello C, Valle J.

Am J Med Genet. 1995 Jun 19;60(3):206-9.

PMID:
7573172
47.

A weak association between TH and DRD2 genes and bipolar affective disorder in a Spanish sample.

Pérez de Castro I, Santos J, Torres P, Visedo G, Saiz-Ruiz J, Llinares C, Fernández-Piqueras J.

J Med Genet. 1995 Feb;32(2):131-4.

48.

Eight new polymorphic microsatellites in mouse gene loci.

Santos J, Pérez de Castro I, Herranz M, Fernández-Piqueras J.

Cytogenet Cell Genet. 1995;71(3):223-4.

PMID:
7587381
49.

No association between dopamine D4 receptor polymorphism and manic depressive illness.

Pérez de Castro I, Torres P, Fernández-Piqueras J, Saiz-Ruiz J, Llinares C.

J Med Genet. 1994 Nov;31(11):897-8. No abstract available.

50.

[Inter-consultations and complementary tests in a health center].

Pérez de Castro I, Romo Espeso B, Liquete Pérez C, Díez García MA.

Aten Primaria. 1991 Feb;8(2):164-5. Spanish. No abstract available.

PMID:
1893047

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