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Proprotein convertase subtilisin/kexin type 9 and lipid metabolism.

Spolitu S, Dai W, Zadroga JA, Ozcan L.

Curr Opin Lipidol. 2019 Jun;30(3):186-191. doi: 10.1097/MOL.0000000000000601.


Hepatic Glucagon Signaling Regulates PCSK9 and Low-Density Lipoprotein Cholesterol.

Spolitu S, Okamoto H, Dai W, Zadroga JA, Wittchen ES, Gromada J, Ozcan L.

Circ Res. 2019 Jan 4;124(1):38-51. doi: 10.1161/CIRCRESAHA.118.313648.


An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1.

Zheng Z, Nayak L, Wang W, Yurdagul A Jr, Wang X, Cai B, Lapping S, Ozcan L, Ramakrishnan R, Pestell RG, Jain MK, Tabas I.

Blood. 2019 Feb 14;133(7):743-753. doi: 10.1182/blood-2018-07-864843. Epub 2018 Dec 1.


Statins are effective in the treatment of benign prostatic hyperplasia with metabolic syndrome.

Cakir SS, Ozcan L, Polat EC, Besiroglu H, Kocaaslan R, Ötunctemur A, Ozbek E.

Aging Male. 2018 Nov 21:1-6. doi: 10.1080/13685538.2018.1541979. [Epub ahead of print]


Photoelectrocatalytic Degradation of Paraquat by Pt Loaded TiO₂ Nanotubes on Ti Anodes.

Özcan L, Mutlu T, Yurdakal S.

Materials (Basel). 2018 Sep 13;11(9). pii: E1715. doi: 10.3390/ma11091715.


A New Activator of Hepatocyte CaMKII in Fasting and Type 2 Diabetes.

Ozcan L, Tabas I.

Diabetes. 2018 Sep;67(9):1742-1744. doi: 10.2337/dbi18-0026. No abstract available.


Beneficial effects of Oltipraz, nuclear factor - erythroid - 2 - related factor 2 (Nrf2), on renal damage in unilateral ureteral obstruction rat model.

Polat EC, Besiroglu H, Ozcan L, Otunctemur A, Eruyar AT, Somay A, Ozbay N, Cekmen M, Eraldemir C, Ozbek E.

Int Braz J Urol. 2018 Nov-Dec;44(6):1243-1251. doi: 10.1590/S1677-5538.IBJU.2018.0232.


A Hepatocyte FOXN3-α Cell Glucagon Axis Regulates Fasting Glucose.

Karanth S, Adams JD, Serrano MLA, Quittner-Strom EB, Simcox J, Villanueva CJ, Ozcan L, Holland WL, Yost HJ, Vella A, Schlegel A.

Cell Rep. 2018 Jul 10;24(2):312-319. doi: 10.1016/j.celrep.2018.06.039.


The effect of prostatic inflammation on clinical outcomes in patients with benign prostate hyperplasia.

Cakir SS, Polat EC, Ozcan L, Besiroglu H, Ötunctemur A, Ozbek E.

Prostate Int. 2018 Jun;6(2):71-74. doi: 10.1016/j.prnil.2017.12.003. Epub 2018 Jan 8.


Neuronal Nitric Oxide Synthase Expression in the Anterior Vaginal Wall of Patients with Stress Urinary Incontinence.

Ozcan L, Polat EC, Onen E, Otunctemur A, Ozbek E, Somay A, Ozbay N.

Urol J. 2018 Sep 26;15(5):280-284. doi: 10.22037/uj.v0i0.3545.


Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance.

Ghorpade DS, Ozcan L, Zheng Z, Nicoloro SM, Shen Y, Chen E, Blüher M, Czech MP, Tabas I.

Nature. 2018 Mar 29;555(7698):673-677. doi: 10.1038/nature26138. Epub 2018 Mar 21.


Visceral adiposity index is associated with premature ejaculation inversely: a cross-sectional study.

Cakir SS, Ozcan L, Besiroglu H, Dursun M, Polat EC, Otunctemur A, Ozbek E.

Aging Male. 2018 Sep;21(3):206-210. doi: 10.1080/13685538.2018.1427712. Epub 2018 Jan 16.


Sexual Dysfunction in Premenopausal Women With Obstructive Sleep Apnea.

Yilmaz Z, Sirinocak PB, Voyvoda B, Ozcan L.

Urol J. 2017 Nov 4;14(6):5051-5056. doi: 10.22037/uj.v14i6.3891.


CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis.

Doran AC, Ozcan L, Cai B, Zheng Z, Fredman G, Rymond CC, Dorweiler B, Sluimer JC, Hsieh J, Kuriakose G, Tall AR, Tabas I.

J Clin Invest. 2017 Nov 1;127(11):4075-4089. doi: 10.1172/JCI94735. Epub 2017 Oct 3.


Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis.

Kim K, Ryu D, Dongiovanni P, Ozcan L, Nayak S, Ueberheide B, Valenti L, Auwerx J, Pajvani UB.

Gastroenterology. 2017 Dec;153(6):1568-1580.e10. doi: 10.1053/j.gastro.2017.08.039. Epub 2017 Aug 30.


Is Axillary Lymph Node Dissection Necessary After a Positive Sentinel Lymph Node Biopsy?

Ozcan LC, Giuliano AE.

Adv Surg. 2017 Sep;51(1):165-178. doi: 10.1016/j.yasu.2017.03.013. Epub 2017 May 13. Review. No abstract available.


Comparison of the clinical parameters of benign prostate hyperplasia in diabetic and non diabetic patients.

Ozcan L, Besiroglu H, Dursun M, Polat EC, Otunctemur A, Ozbek E.

Arch Ital Urol Androl. 2017 Mar 31;89(1):26-30. doi: 10.4081/aiua.2017.1.26.


Effects of taking tadalafil 5 mg once daily on erectile function and total testosterone levels in patients with metabolic syndrome.

Ozcan L, Polat EC, Kocaaslan R, Onen E, Otunctemur A, Ozbek E.

Andrologia. 2017 Nov;49(9). doi: 10.1111/and.12751. Epub 2017 Mar 15.


Interobserver variability in Gleason histological grading of prostate cancer.

Ozkan TA, Eruyar AT, Cebeci OO, Memik O, Ozcan L, Kuskonmaz I.

Scand J Urol. 2016 Dec;50(6):420-424. Epub 2016 Jul 14.


Calcium signalling and ER stress in insulin resistance and atherosclerosis.

Ozcan L, Tabas I.

J Intern Med. 2016 Nov;280(5):457-464. doi: 10.1111/joim.12562. Epub 2016 Oct 14. Review.


Low serum Insulin Like Growth Factor - 1 in patients with Stress Urinary Incontinence.

Ozbek E, Otunctemur A, Sahin S, Ozcan L, Dursun M, Polat E, Tulubas F, Cekmen M.

Int Braz J Urol. 2016 Jul-Aug;42(4):787-92. doi: 10.1590/S1677-5538.IBJU.2015.0453.


Electrochemical Determination of Bisphenol A with Pencil Graphite Electrodes Modified with Co(II), Ni(II), Cu(II) and Fe(II) Phthalocyaninetetrasulfonates.

Özcan L, Altuntas M, Büyüksagis A, Türk H, Yurdakal S.

Anal Sci. 2016;32(8):881-6. doi: 10.2116/analsci.32.881.


Hepatocyte DACH1 Is Increased in Obesity via Nuclear Exclusion of HDAC4 and Promotes Hepatic Insulin Resistance.

Ozcan L, Ghorpade DS, Zheng Z, de Souza JC, Chen K, Bessler M, Bagloo M, Schrope B, Pestell R, Tabas I.

Cell Rep. 2016 Jun 7;15(10):2214-2225. doi: 10.1016/j.celrep.2016.05.006. Epub 2016 May 26.


Effects of Tadalafil 5 mg Dosed Once Daily in Men with Premature Ejaculation.

Ozcan L, Polat EC, Onen E, Kocaaslan R, Otunctemur A, Cekmen M, Eraldemir C, Ozbek E.

Urol Int. 2017;98(2):210-214. doi: 10.1159/000445839. Epub 2016 May 4.


Relation of urinary stone disease with androgenetic alopecia and serum testosterone levels.

Polat EC, Ozcan L, Otunctemur A, Ozbek E.

Urolithiasis. 2016 Oct;44(5):409-13. doi: 10.1007/s00240-016-0888-3. Epub 2016 May 7.


Low serum insulin-like growth factor-1 in patients with erectile dysfunction.

Otunctemur A, Ozbek E, Sahin S, Ozcan L, Dursun M, Polat EC, Cekmen M, Ozsoy OD, Erkoc M, Danis E, Bozkurt M.

Basic Clin Androl. 2016 Jan 28;26:1. doi: 10.1186/s12610-015-0028-x. eCollection 2016.


Re: The association of urolithiasis and androgenetic alopecia. Resorlu M, Sancak EB, Uysal F, Arslan M, Diri A, Adam G, Akbas A, Sariyildirim A, Gulpinar MT, Resorlu B. Ren Fail. 2015 Oct 13:1-5.

Otunctemur A, Polat EC, Ozbek E, Ozcan L.

Ren Fail. 2016;38(3):347. doi: 10.3109/0886022X.2015.1128449. Epub 2016 Jan 4. No abstract available.


Relationship between Calcium Stone Disease and Metabolic Syndrome.

Polat EC, Ozcan L, Cakir SS, Dursun M, Otunctemur A, Ozbek E.

Urol J. 2015 Dec 23;12(6):2391-5.


Behçet's Disease Detecting by Attacks of Recurrent Epididymo-Orchitis: Case Reports.

Ulukaradag E, Memik O, Voyvoda B, Ozcan L.

Urol J. 2015 Nov 14;12(5):2379-80. No abstract available.


Erectile Dysfunction Is Positively Correlated with Mean Platelet Volume and Platelet Count, but Not with Eosinophil Count in Peripheral Blood.

Otunctemur A, Bozkurt M, Besiroglu H, Polat EC, Ozcan L, Ozbek E.

Urol J. 2015 Nov 14;12(5):2347-52.


Comparison between Retroperitoneal and Transperitoneal Approaches in the Laparoscopic Treatment of Bosniak Type I Renal Cysts: A Retrospective Study.

Ozcan L, Polat EC, Onen E, Cebeci OO, Memik O, Voyvoda B, Ulukaradag E, Kara BY.

Urol J. 2015 Sep 4;12(4):2218-22.


Suppression of Adaptive Immune Cell Activation Does Not Alter Innate Immune Adipose Inflammation or Insulin Resistance in Obesity.

Subramanian M, Ozcan L, Ghorpade DS, Ferrante AW Jr, Tabas I.

PLoS One. 2015 Aug 28;10(8):e0135842. doi: 10.1371/journal.pone.0135842. eCollection 2015.


Internal urethrotomy versus plasmakinetic energy for surgical treatment of urethral stricture.

Ozcan L, Polat EC, Otunctemur A, Onen E, Cebeci OO, Memik O, Voyvoda B, Ulukaradag E, Ozkan TA, Sener M, Ozbek E.

Arch Ital Urol Androl. 2015 Jul 7;87(2):161-4. doi: 10.4081/aiua.2015.2.161.


Treatment of Obese Insulin-Resistant Mice With an Allosteric MAPKAPK2/3 Inhibitor Lowers Blood Glucose and Improves Insulin Sensitivity.

Ozcan L, Xu X, Deng SX, Ghorpade DS, Thomas T, Cremers S, Hubbard B, Serrano-Wu MH, Gaestel M, Landry DW, Tabas I.

Diabetes. 2015 Oct;64(10):3396-405. doi: 10.2337/db14-1945. Epub 2015 Jun 11.


Beneficial effects montelukast, cysteinyl-leukotriene receptor antagonist, on renal damage after unilateral ureteral obstruction in rats.

Otunctemur A, Ozbek E, Cakir SS, Dursun M, Cekmen M, Polat EC, Ozcan L, Somay A, Ozbay N.

Int Braz J Urol. 2015 Mar-Apr;41(2):279-87. doi: 10.1590/S1677-5538.IBJU.2015.02.14.


Giant bladder calculi: a case report.

Polat EC, Ozcan L, Otunctemur A, Ozbek E.

Urol J. 2015 Apr 29;12(2):2122-3. No abstract available.


Urolithiasis is associated with low serum testosterone levels in men.

Otunctemur A, Ozbek E, Cakir SS, Dursun M, Polat EC, Ozcan L, Besiroglu H.

Arch Ital Urol Androl. 2015 Mar 31;87(1):83-6. doi: 10.4081/aiua.2015.1.83.


The comparison of GLUT-4 and nNOS expression in diabetic and non-diabetic patients with BPH/LUTS.

Otunctemur A, Besiroglu H, Dursun M, Ozcan L, Polat EC, Somay A, Ozbay N, Ozer K, Ozbek E.

Int Urol Nephrol. 2015 Jun;47(6):899-904. doi: 10.1007/s11255-015-0964-6. Epub 2015 Apr 3.


Duloxetine, dual serotonin and norepinephrine reuptake inhibitor, versus paroxetine, selective serotonin reuptake inhibitor, in the treatment for premature ejaculation.

Ozcan L, Polat EC, Otunctemur A, Ozbek E.

Int Urol Nephrol. 2015 Feb;47(2):283-7. doi: 10.1007/s11255-014-0905-9. Epub 2015 Jan 4.


Genetic polymorphism in the serotonin transporter gene-linked polymorphic region and response to serotonin reuptake inhibitors in patients with premature ejaculation.

Ozbek E, Otunctemur A, Simsek A, Polat EC, Ozcan L, Köse O, Cekmen M.

Clinics (Sao Paulo). 2014 Nov;69(11):710-3. doi: 10.6061/clinics/2014(11)01.


Association of erectile dysfunction and urolithiasis.

Otunctemur A, Ozbek E, Cakir SS, Dursun M, Polat EC, Ozcan L, Kose O, Besiroglu H.

Arch Ital Urol Androl. 2014 Sep 30;86(3):215-6. doi: 10.4081/aiua.2014.3.215.


Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway.

Fredman G, Ozcan L, Spolitu S, Hellmann J, Spite M, Backs J, Tabas I.

Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14530-5. doi: 10.1073/pnas.1410851111. Epub 2014 Sep 22.


CaMKII in cardiometabolic disease.

Ozcan L, Tabas I.

Aging (Albany NY). 2014 Jun;6(6):430-1. No abstract available.


Common therapeutic targets in cardiometabolic disease.

Fredman G, Ozcan L, Tabas I.

Sci Transl Med. 2014 Jun 4;6(239):239ps5. doi: 10.1126/scitranslmed.3008908. Review.


Combination therapy with selective serotonin reuptake inhibitors and phosphodiesterase-5 inhibitors in the treatment of premature ejaculation.

Polat EC, Ozbek E, Otunctemur A, Ozcan L, Simsek A.

Andrologia. 2015 Jun;47(5):487-92. doi: 10.1111/and.12289. Epub 2014 May 9.


Activation of calcium/calmodulin-dependent protein kinase II in obesity mediates suppression of hepatic insulin signaling.

Ozcan L, Cristina de Souza J, Harari AA, Backs J, Olson EN, Tabas I.

Cell Metab. 2013 Dec 3;18(6):803-15. doi: 10.1016/j.cmet.2013.10.011. Epub 2013 Nov 21.


Relevance of serum nitric oxide levels and the efficacy of selective serotonin reuptake inhibitors treatment on premature ejaculation: decreased nitric oxide is associated with premature ejaculation.

Otunctemur A, Ozbek E, Kirecci SL, Ozcan L, Dursun M, Cekmen M, Ozdogan HK.

Andrologia. 2014;46(9):951-5. doi: 10.1111/and.12179. Epub 2013 Oct 11.


Lack of significant difference between internal spermatic vein and brachial vein ischemia modified albumin levels in patients with varicocele.

Aliyazicioglu Y, Ozbek E, Ozcan L, Cakir SS, Dursun M.

Arch Ital Urol Androl. 2013 Apr 19;85(1):34-5. doi: 10.4081/aiua.2013.1.34.


Synthesis, conformational and spectroscopic characterization of monomeric styrene derivatives having pendant p-substituted benzylic ether groups.

Cinar M, Ozcan L, Karabacak M, Erol I.

Spectrochim Acta A Mol Biomol Spectrosc. 2013 Jul;111:97-103. doi: 10.1016/j.saa.2013.03.084. Epub 2013 Mar 28.


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