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Items: 26

1.

Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma.

Veschi V, Liu Z, Voss TC, Ozbun L, Gryder B, Yan C, Hu Y, Ma A, Jin J, Mazur SJ, Lam N, Souza BK, Giannini G, Hager GL, Arrowsmith CH, Khan J, Appella E, Thiele CJ.

Cancer Cell. 2017 Jan 9;31(1):50-63. doi: 10.1016/j.ccell.2016.12.002.

2.

Selective inhibition of regulatory T cells by targeting the PI3K-Akt pathway.

Abu-Eid R, Samara RN, Ozbun L, Abdalla MY, Berzofsky JA, Friedman KM, Mkrtichyan M, Khleif SN.

Cancer Immunol Res. 2014 Nov;2(11):1080-9. doi: 10.1158/2326-6066.CIR-14-0095. Epub 2014 Jul 30.

3.

Episomal expression of truncated listeriolysin O in LmddA-LLO-E7 vaccine enhances antitumor efficacy by preferentially inducing expansions of CD4+FoxP3- and CD8+ T cells.

Chen Z, Ozbun L, Chong N, Wallecha A, Berzofsky JA, Khleif SN.

Cancer Immunol Res. 2014 Sep;2(9):911-22. doi: 10.1158/2326-6066.CIR-13-0197. Epub 2014 May 28.

4.

B7-DC-Ig enhances vaccine effect by a novel mechanism dependent on PD-1 expression level on T cell subsets.

Mkrtichyan M, Najjar YG, Raulfs EC, Liu L, Langerman S, Guittard G, Ozbun L, Khleif SN.

J Immunol. 2012 Sep 1;189(5):2338-47. doi: 10.4049/jimmunol.1103085. Epub 2012 Jul 25.

5.

Identification of a potential ovarian cancer stem cell gene expression profile from advanced stage papillary serous ovarian cancer.

Vathipadiekal V, Saxena D, Mok SC, Hauschka PV, Ozbun L, Birrer MJ.

PLoS One. 2012;7(1):e29079. doi: 10.1371/journal.pone.0029079. Epub 2012 Jan 17.

6.

Identification of novel therapeutic targets in microdissected clear cell ovarian cancers.

Stany MP, Vathipadiekal V, Ozbun L, Stone RL, Mok SC, Xue H, Kagami T, Wang Y, McAlpine JN, Bowtell D, Gout PW, Miller DM, Gilks CB, Huntsman DG, Ellard SL, Wang YZ, Vivas-Mejia P, Lopez-Berestein G, Sood AK, Birrer MJ.

PLoS One. 2011;6(7):e21121. doi: 10.1371/journal.pone.0021121. Epub 2011 Jul 6.

7.

Regulation of tumor angiogenesis by EZH2.

Lu C, Han HD, Mangala LS, Ali-Fehmi R, Newton CS, Ozbun L, Armaiz-Pena GN, Hu W, Stone RL, Munkarah A, Ravoori MK, Shahzad MM, Lee JW, Mora E, Langley RR, Carroll AR, Matsuo K, Spannuth WA, Schmandt R, Jennings NB, Goodman BW, Jaffe RB, Nick AM, Kim HS, Guven EO, Chen YH, Li LY, Hsu MC, Coleman RL, Calin GA, Denkbas EB, Lim JY, Lee JS, Kundra V, Birrer MJ, Hung MC, Lopez-Berestein G, Sood AK.

Cancer Cell. 2010 Aug 9;18(2):185-97. doi: 10.1016/j.ccr.2010.06.016.

8.

A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2.

Mok SC, Bonome T, Vathipadiekal V, Bell A, Johnson ME, Wong KK, Park DC, Hao K, Yip DK, Donninger H, Ozbun L, Samimi G, Brady J, Randonovich M, Pise-Masison CA, Barrett JC, Wong WH, Welch WR, Berkowitz RS, Birrer MJ.

Cancer Cell. 2009 Dec 8;16(6):521-32. doi: 10.1016/j.ccr.2009.10.018.

9.

Matrilysin-1 mediates bronchiolization of alveoli, a potential premalignant change in lung cancer.

Wang XY, Demelash A, Kim H, Jensen-Taubman S, Dakir el H, Ozbun L, Birrer MJ, Linnoila RI.

Am J Pathol. 2009 Aug;175(2):592-604. doi: 10.2353/ajpath.2009.080461. Epub 2009 Jul 16.

10.

Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.

Lorenzi PL, Llamas J, Gunsior M, Ozbun L, Reinhold WC, Varma S, Ji H, Kim H, Hutchinson AA, Kohn EC, Goldsmith PK, Birrer MJ, Weinstein JN.

Mol Cancer Ther. 2008 Oct;7(10):3123-8. doi: 10.1158/1535-7163.MCT-08-0589.

11.

A gene signature predicting for survival in suboptimally debulked patients with ovarian cancer.

Bonome T, Levine DA, Shih J, Randonovich M, Pise-Masison CA, Bogomolniy F, Ozbun L, Brady J, Barrett JC, Boyd J, Birrer MJ.

Cancer Res. 2008 Jul 1;68(13):5478-86. doi: 10.1158/0008-5472.CAN-07-6595.

12.

Classification of ovarian cancer: a genomic analysis.

Stany MP, Bonome T, Wamunyokoli F, Zorn K, Ozbun L, Park DC, Hao K, Boyd J, Sood AK, Gershenson DM, Berkowitz RS, Mok SC, Birrer MJ.

Adv Exp Med Biol. 2008;622:23-33. doi: 10.1007/978-0-387-68969-2_3. Review. No abstract available.

PMID:
18546616
13.

Genomic analysis of epithelial ovarian cancer.

Farley J, Ozbun LL, Birrer MJ.

Cell Res. 2008 May;18(5):538-48. doi: 10.1038/cr.2008.52. Review.

14.

Intracellular proadrenomedullin-derived peptides decorate the microtubules and contribute to cytoskeleton function.

Sackett DL, Ozbun L, Zudaire E, Wessner L, Chirgwin JM, Cuttitta F, Martínez A.

Endocrinology. 2008 Jun;149(6):2888-98. doi: 10.1210/en.2007-1763. Epub 2008 Mar 6.

15.

Cell cycle and related protein.

Farley J, Ozbun L, Samimi G, Birrer MJ.

Dis Markers. 2007;23(5-6):433-43. Review. No abstract available.

16.

Biomarkers of mucinous tumors of the ovary.

Samimi G, Ozbun L, Johnson ME, Mok SC, Birrer MJ.

Dis Markers. 2007;23(5-6):389-96. No abstract available.

17.

Etiology and pathogenesis of epithelial ovarian cancer.

Mok SC, Kwong J, Welch WR, Samimi G, Ozbun L, Bonome T, Birrer MJ, Berkowitz RS, Wong KK.

Dis Markers. 2007;23(5-6):367-76. Review.

18.
19.

Characterization of adrenomedullin in non-human primates.

Zudaire E, Martínez A, Ozbun LL, Cuttitta F.

Biochem Biophys Res Commun. 2004 Sep 3;321(4):859-69.

PMID:
15358106
20.

Nkx2.1 transcription factor in lung cells and a transforming growth factor-beta1 heterozygous mouse model of lung carcinogenesis.

Kang Y, Hebron H, Ozbun L, Mariano J, Minoo P, Jakowlew SB.

Mol Carcinog. 2004 Aug;40(4):212-31.

PMID:
15264213
21.

Depressed adrenomedullin in the embryonic transforming growth factor-beta1 null mouse becomes elevated postnatally.

Bodegas E, Martínez A, Ozbun LL, Garayoa M, Letterio JJ, Montuenga LM, Jakowlew SB.

Int J Dev Biol. 2004 Feb;48(1):67-70.

22.

Differentially expressed nucleolar TGF-beta1 target (DENTT) in mouse development.

Ozbun LL, Martínez A, Angdisen J, Umphress S, Kang Y, Wang M, You M, Jakowlew SB.

Dev Dyn. 2003 Mar;226(3):491-511.

23.

Altered expression of G1/S regulatory genes occurs early and frequently in lung carcinogenesis in transforming growth factor-beta1 heterozygous mice.

Kang Y, Ozbun LL, Angdisen J, Moody TW, Prentice M, Diwan BA, Jakowlew SB.

Carcinogenesis. 2002 Jul;23(7):1217-27.

PMID:
12117781
24.
25.

Indomethacin reduces lung adenoma number in A/J mice.

Moody TW, Leyton J, Zakowicz H, Hida T, Kang Y, Jakowlew S, You L, Ozbun L, Zia H, Youngberg J, Malkinson A.

Anticancer Res. 2001 May-Jun;21(3B):1749-55.

PMID:
11497255
26.

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