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Items: 1 to 50 of 216

1.

Maternal Allopurinol Prevents Cardiac Dysfunction in Adult Male Offspring Programmed by Chronic Hypoxia During Pregnancy.

Niu Y, Kane AD, Lusby CM, Allison BJ, Chua YY, Kaandorp JJ, Nevin-Dolan R, Ashmore TJ, Blackmore HL, Derks JB, Ozanne SE, Giussani DA.

Hypertension. 2018 Oct;72(4):971-978. doi: 10.1161/HYPERTENSIONAHA.118.11363.

2.

Maternal exercise intervention in obese pregnancy improves the cardiovascular health of the adult male offspring.

Beeson JH, Blackmore HL, Carr SK, Dearden L, Duque-Guimarães DE, Kusinski LC, Pantaleão LC, Pinnock AG, Aiken CE, Giussani DA, Fernandez-Twinn DS, Ozanne SE.

Mol Metab. 2018 Oct;16:35-44. doi: 10.1016/j.molmet.2018.06.009. Epub 2018 Jun 18.

3.

Programming of central and peripheral insulin resistance by low birthweight and postnatal catch-up growth in male mice.

Berends LM, Dearden L, Tung YCL, Voshol P, Fernandez-Twinn DS, Ozanne SE.

Diabetologia. 2018 Oct;61(10):2225-2234. doi: 10.1007/s00125-018-4694-z. Epub 2018 Jul 24.

4.

A suboptimal maternal diet combined with accelerated postnatal growth results in an altered aging profile in the thymus of male rats.

Tarry-Adkins JL, Aiken CE, Ashmore TJ, Fernandez-Twinn DS, Chen JH, Ozanne SE.

FASEB J. 2018 Jul 5:fj201701350RR. doi: 10.1096/fj.201701350RR. [Epub ahead of print]

5.

Sex and gender differences in developmental programming of metabolism.

Dearden L, Bouret SG, Ozanne SE.

Mol Metab. 2018 Sep;15:8-19. doi: 10.1016/j.molmet.2018.04.007. Epub 2018 Apr 30. Review.

6.

Maternal diet-induced obesity programmes cardiac dysfunction in male mice independently of post-weaning diet.

Loche E, Blackmore HL, Carpenter AA, Beeson JH, Pinnock A, Ashmore TJ, Aiken CE, de Almeida-Faria J, Schoonejans JM, Giussani DA, Fernandez-Twinn DS, Ozanne SE.

Cardiovasc Res. 2018 Aug 1;114(10):1372-1384. doi: 10.1093/cvr/cvy082.

7.

Insulin-signalling dysregulation and inflammation is programmed trans-generationally in a female rat model of poor maternal nutrition.

Tarry-Adkins JL, Aiken CE, Ashmore TJ, Ozanne SE.

Sci Rep. 2018 Mar 5;8(1):4014. doi: 10.1038/s41598-018-22383-w.

8.

Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species.

Lowe R, Barton C, Jenkins CA, Ernst C, Forman O, Fernandez-Twinn DS, Bock C, Rossiter SJ, Faulkes CG, Ozanne SE, Walter L, Odom DT, Mellersh C, Rakyan VK.

Genome Biol. 2018 Feb 16;19(1):22. doi: 10.1186/s13059-018-1397-1.

9.

Telomere Length Analysis: A Tool for Dissecting Aging Mechanisms in Developmental Programming.

Tarry-Adkins JL, Ozanne SE.

Methods Mol Biol. 2018;1735:351-363. doi: 10.1007/978-1-4939-7614-0_24.

PMID:
29380327
10.

Small RNA Sequencing: A Technique for miRNA Profiling.

Pantaleão LC, Ozanne SE.

Methods Mol Biol. 2018;1735:321-330. doi: 10.1007/978-1-4939-7614-0_21.

PMID:
29380324
11.

Generation of the Maternal Low-Protein Rat Model for Studies of Metabolic Disorders.

Ma D, Ozanne SE, Guest PC.

Methods Mol Biol. 2018;1735:201-206. doi: 10.1007/978-1-4939-7614-0_10.

PMID:
29380313
12.

Somatic growth and telomere dynamics in vertebrates: relationships, mechanisms and consequences.

Monaghan P, Ozanne SE.

Philos Trans R Soc Lond B Biol Sci. 2018 Mar 5;373(1741). pii: 20160446. doi: 10.1098/rstb.2016.0446. Review.

PMID:
29335370
13.

Epigenetics and DOHaD: from basics to birth and beyond.

Bianco-Miotto T, Craig JM, Gasser YP, van Dijk SJ, Ozanne SE.

J Dev Orig Health Dis. 2017 Oct;8(5):513-519. doi: 10.1017/S2040174417000733. Epub 2017 Sep 11. Review.

PMID:
28889823
14.

Systematic review indicates postnatal growth in term infants born small-for-gestational-age being associated with later neurocognitive and metabolic outcomes.

Castanys-Muñoz E, Kennedy K, Castañeda-Gutiérrez E, Forsyth S, Godfrey KM, Koletzko B, Ozanne SE, Rueda R, Schoemaker M, van der Beek EM, van Buuren S, Ong KK.

Acta Paediatr. 2017 Aug;106(8):1230-1238. doi: 10.1111/apa.13868. Epub 2017 May 15. Review.

15.

A Western-style obesogenic diet alters maternal metabolic physiology with consequences for fetal nutrient acquisition in mice.

Musial B, Vaughan OR, Fernandez-Twinn DS, Voshol P, Ozanne SE, Fowden AL, Sferruzzi-Perri AN.

J Physiol. 2017 Jul 15;595(14):4875-4892. doi: 10.1113/JP273684. Epub 2017 Apr 5.

16.

SILAC Mass Spectrometry Profiling: A Psychiatric Disorder Perspective.

Duque-Guimarães D, Ong TP, de Almeida-Faria J, Guest PC, Ozanne SE.

Adv Exp Med Biol. 2017;974:289-298. doi: 10.1007/978-3-319-52479-5_27.

PMID:
28353248
17.

A Protocol for Producing the Maternal Low-Protein Rat Model: A Tool for Preclinical Proteomic Studies.

Ma D, Ozanne SE, Guest PC.

Adv Exp Med Biol. 2017;974:251-255. doi: 10.1007/978-3-319-52479-5_22.

PMID:
28353243
18.

A post-weaning obesogenic diet exacerbates the detrimental effects of maternal obesity on offspring insulin signaling in adipose tissue.

de Almeida Faria J, Duque-Guimarães D, Carpenter AA, Loche E, Ozanne SE.

Sci Rep. 2017 Mar 24;7:44949. doi: 10.1038/srep44949.

19.

Exercise rescues obese mothers' insulin sensitivity, placental hypoxia and male offspring insulin sensitivity.

Fernandez-Twinn DS, Gascoin G, Musial B, Carr S, Duque-Guimaraes D, Blackmore HL, Alfaradhi MZ, Loche E, Sferruzzi-Perri AN, Fowden AL, Ozanne SE.

Sci Rep. 2017 Mar 14;7:44650. doi: 10.1038/srep44650.

20.

Breaking the cycle of intergenerational obesity.

Aiken CE, Ozanne SE.

J Physiol. 2017 Mar 1;595(5):1443-1444. doi: 10.1113/JP273821. Epub 2017 Feb 1. No abstract available.

21.

Pulsed SILAC as a Approach for miRNA Targets Identification in Cell Culture.

Duque-Guimarães DE, de Almeida-Faria J, Ong TP, Ozanne SE.

Methods Mol Biol. 2017;1546:149-159.

PMID:
27896764
22.

Multiplex Biomarker Approaches in Type 2 Diabetes Mellitus Research.

Ozanne SE, Rahmoune H, Guest PC.

Methods Mol Biol. 2017;1546:37-55. Review.

PMID:
27896756
23.

Maternal Obesity in Pregnancy Developmentally Programs Adipose Tissue Inflammation in Young, Lean Male Mice Offspring.

Alfaradhi MZ, Kusinski LC, Fernandez-Twinn DS, Pantaleão LC, Carr SK, Ferland-McCollough D, Yeo GS, Bushell M, Ozanne SE.

Endocrinology. 2016 Nov;157(11):4246-4256. Epub 2016 Sep 1.

24.

Nutrition in early life and age-associated diseases.

Tarry-Adkins JL, Ozanne SE.

Ageing Res Rev. 2017 Oct;39:96-105. doi: 10.1016/j.arr.2016.08.003. Epub 2016 Sep 1. Review.

PMID:
27594376
25.

Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats.

Tarry-Adkins JL, Fernandez-Twinn DS, Chen JH, Hargreaves IP, Neergheen V, Aiken CE, Ozanne SE.

Dis Model Mech. 2016 Oct 1;9(10):1221-1229. Epub 2016 Sep 1.

26.

Early nutrition, epigenetics, and cardiovascular disease.

Loche E, Ozanne SE.

Curr Opin Lipidol. 2016 Oct;27(5):449-58. doi: 10.1097/MOL.0000000000000338. Review.

PMID:
27495135
27.

Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice.

Holland ML, Lowe R, Caton PW, Gemma C, Carbajosa G, Danson AF, Carpenter AA, Loche E, Ozanne SE, Rakyan VK.

Science. 2016 Jul 29;353(6298):495-8. doi: 10.1126/science.aaf7040. Epub 2016 Jul 7.

28.

Transgenerational effects of maternal diet on metabolic and reproductive ageing.

Aiken CE, Tarry-Adkins JL, Ozanne SE.

Mamm Genome. 2016 Aug;27(7-8):430-9. doi: 10.1007/s00335-016-9631-1. Epub 2016 Apr 25. Review.

29.

Association of birth weight and the development of antipsychotic induced adiposity in individuals with treatment resistant schizophrenia.

Ziauddeen H, Garcia-Rizo C, Bernardo M, Kirkpatrick B, Ozanne SE, Jones PB, Fernandez-Egea E.

Eur Neuropsychopharmacol. 2016 Jun;26(6):972-8. doi: 10.1016/j.euroneuro.2016.03.008. Epub 2016 Mar 26.

PMID:
27107738
30.

Non-Genetic Transmission of Obesity - It's in Your Epigenes.

Loche E, Ozanne SE.

Trends Endocrinol Metab. 2016 Jun;27(6):349-350. doi: 10.1016/j.tem.2016.04.003. Epub 2016 Apr 16.

PMID:
27091491
31.

Developmental programming: State-of-the-science and future directions-Summary from a Pennington Biomedical symposium.

Sutton EF, Gilmore LA, Dunger DB, Heijmans BT, Hivert MF, Ling C, Martinez JA, Ozanne SE, Simmons RA, Szyf M, Waterland RA, Redman LM, Ravussin E.

Obesity (Silver Spring). 2016 May;24(5):1018-26. doi: 10.1002/oby.21487. Epub 2016 Apr 1. Review.

32.

Cell-autonomous programming of rat adipose tissue insulin signalling proteins by maternal nutrition.

Martin-Gronert MS, Fernandez-Twinn DS, Bushell M, Siddle K, Ozanne SE.

Diabetologia. 2016 Jun;59(6):1266-75. doi: 10.1007/s00125-016-3905-8. Epub 2016 Mar 10.

33.

Divergence of mechanistic pathways mediating cardiovascular aging and developmental programming of cardiovascular disease.

Allison BJ, Kaandorp JJ, Kane AD, Camm EJ, Lusby C, Cross CM, Nevin-Dolan R, Thakor AS, Derks JB, Tarry-Adkins JL, Ozanne SE, Giussani DA.

FASEB J. 2016 May;30(5):1968-75. doi: 10.1096/fj.201500057. Epub 2016 Mar 1.

34.

The effects of aging and maternal protein restriction during lactation on thymic involution and peripheral immunosenescence in adult mice.

Heppolette CA, Chen JH, Carr SK, Palmer DB, Ozanne SE.

Oncotarget. 2016 Feb 9;7(6):6398-409. doi: 10.18632/oncotarget.7176.

35.

Oxidative stress and life histories: unresolved issues and current needs.

Speakman JR, Blount JD, Bronikowski AM, Buffenstein R, Isaksson C, Kirkwood TB, Monaghan P, Ozanne SE, Beaulieu M, Briga M, Carr SK, Christensen LL, Cochemé HM, Cram DL, Dantzer B, Harper JM, Jurk D, King A, Noguera JC, Salin K, Sild E, Simons MJ, Smith S, Stier A, Tobler M, Vitikainen E, Peaker M, Selman C.

Ecol Evol. 2015 Nov 17;5(24):5745-57. doi: 10.1002/ece3.1790. eCollection 2015 Dec.

36.

5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats.

Martin-Gronert MS, Stocker CJ, Wargent ET, Cripps RL, Garfield AS, Jovanovic Z, D'Agostino G, Yeo GS, Cawthorne MA, Arch JR, Heisler LK, Ozanne SE.

Dis Model Mech. 2016 Apr;9(4):401-12. doi: 10.1242/dmm.023903. Epub 2016 Jan 14.

37.

Proximity to Delivery Alters Insulin Sensitivity and Glucose Metabolism in Pregnant Mice.

Musial B, Fernandez-Twinn DS, Vaughan OR, Ozanne SE, Voshol P, Sferruzzi-Perri AN, Fowden AL.

Diabetes. 2016 Apr;65(4):851-60. doi: 10.2337/db15-1531. Epub 2016 Jan 6.

38.

Coenzyme Q10 prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth.

Tarry-Adkins JL, Fernandez-Twinn DS, Hargreaves IP, Neergheen V, Aiken CE, Martin-Gronert MS, McConnell JM, Ozanne SE.

Am J Clin Nutr. 2016 Feb;103(2):579-88. doi: 10.3945/ajcn.115.119834. Epub 2015 Dec 30.

39.

Decreased ovarian reserve, dysregulation of mitochondrial biogenesis, and increased lipid peroxidation in female mouse offspring exposed to an obesogenic maternal diet.

Aiken CE, Tarry-Adkins JL, Penfold NC, Dearden L, Ozanne SE.

FASEB J. 2016 Apr;30(4):1548-56. doi: 10.1096/fj.15-280800. Epub 2015 Dec 23.

40.

Ageing is associated with molecular signatures of inflammation and type 2 diabetes in rat pancreatic islets.

Sandovici I, Hammerle CM, Cooper WN, Smith NH, Tarry-Adkins JL, Dunmore BJ, Bauer J, Andrews SR, Yeo GS, Ozanne SE, Constância M.

Diabetologia. 2016 Mar;59(3):502-11. doi: 10.1007/s00125-015-3837-8. Epub 2015 Dec 23.

41.

Transgenerational Developmental Programming of Ovarian Reserve.

Aiken CE, Tarry-Adkins JL, Ozanne SE.

Sci Rep. 2015 Nov 3;5:16175. doi: 10.1038/srep16175.

42.

Impact of maternal undernutrition around the time of conception on factors regulating hepatic lipid metabolism and microRNAs in singleton and twin fetuses.

Lie S, Morrison JL, Williams-Wyss O, Suter CM, Humphreys DT, Ozanne SE, Zhang S, MacLaughlin SM, Kleemann DO, Walker SK, Roberts CT, McMillen IC.

Am J Physiol Endocrinol Metab. 2016 Jan 15;310(2):E148-59. doi: 10.1152/ajpendo.00600.2014. Epub 2015 Oct 20.

43.

The early origins of obesity and insulin resistance: timing, programming and mechanisms.

Nicholas LM, Morrison JL, Rattanatray L, Zhang S, Ozanne SE, McMillen IC.

Int J Obes (Lond). 2016 Feb;40(2):229-38. doi: 10.1038/ijo.2015.178. Epub 2015 Sep 14. Review.

PMID:
26367335
44.

Early life origins of metabolic disease: Developmental programming of hypothalamic pathways controlling energy homeostasis.

Dearden L, Ozanne SE.

Front Neuroendocrinol. 2015 Oct;39:3-16. doi: 10.1016/j.yfrne.2015.08.001. Epub 2015 Aug 19. Review.

PMID:
26296796
45.

Impact of periconceptional and preimplantation undernutrition on factors regulating myogenesis and protein synthesis in muscle of singleton and twin fetal sheep.

Lie S, Morrison JL, Williams-Wyss O, Suter CM, Humphreys DT, Ozanne SE, Zhang S, MacLaughlin SM, Kleemann DO, Walker SK, Roberts CT, McMillen IC.

Physiol Rep. 2015 Aug;3(8). pii: e12495. doi: 10.14814/phy2.12495.

46.

Coenzyme Q10 Prevents Insulin Signaling Dysregulation and Inflammation Prior to Development of Insulin Resistance in Male Offspring of a Rat Model of Poor Maternal Nutrition and Accelerated Postnatal Growth.

Tarry-Adkins JL, Fernandez-Twinn DS, Madsen R, Chen JH, Carpenter A, Hargreaves IP, McConnell JM, Ozanne SE.

Endocrinology. 2015 Oct;156(10):3528-37. doi: 10.1210/en.2015-1424. Epub 2015 Jul 27.

47.

Postnatal growth in preterm infants and later health outcomes: a systematic review.

Ong KK, Kennedy K, Castañeda-Gutiérrez E, Forsyth S, Godfrey KM, Koletzko B, Latulippe ME, Ozanne SE, Rueda R, Schoemaker MH, van der Beek EM, van Buuren S, Fewtrell M.

Acta Paediatr. 2015 Oct;104(10):974-86. doi: 10.1111/apa.13128. Review.

48.

Prenatal undernutrition and leukocyte telomere length in late adulthood: the Dutch famine birth cohort study.

de Rooij SR, van Pelt AM, Ozanne SE, Korver CM, van Daalen SK, Painter RC, Schwab M, Viegas MH, Roseboom TJ.

Am J Clin Nutr. 2015 Sep;102(3):655-60. doi: 10.3945/ajcn.115.112326. Epub 2015 Jul 15.

PMID:
26178721
49.

Developmental programming by maternal obesity in 2015: Outcomes, mechanisms, and potential interventions.

Penfold NC, Ozanne SE.

Horm Behav. 2015 Nov;76:143-52. doi: 10.1016/j.yhbeh.2015.06.015. Epub 2015 Jul 2. Review.

PMID:
26145566
50.

Intergenerational epigenetic inheritance in models of developmental programming of adult disease.

Fernandez-Twinn DS, Constância M, Ozanne SE.

Semin Cell Dev Biol. 2015 Jul;43:85-95. doi: 10.1016/j.semcdb.2015.06.006. Epub 2015 Jun 30. Review.

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