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Items: 1 to 50 of 65

1.

ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.

Kato H, Okabe K, Miyake M, Hattori K, Fukaya T, Tanimoto K, Beini S, Mizuguchi M, Torii S, Arakawa S, Ono M, Saito Y, Sugiyama T, Funatsu T, Sato K, Shimizu S, Oyadomari S, Ichijo H, Kadowaki H, Nishitoh H.

Life Sci Alliance. 2020 Feb 6;3(3). pii: e201900576. doi: 10.26508/lsa.201900576. Print 2020 Mar.

2.

Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation.

Stevens AM, Xiang M, Heppler LN, Tošić I, Jiang K, Munoz JO, Gaikwad AS, Horton TM, Long X, Narayanan P, Seashore EL, Terrell MC, Rashid R, Krueger MJ, Mangubat-Medina AE, Ball ZT, Sumazin P, Walker SR, Hamada Y, Oyadomari S, Redell MS, Frank DA.

Blood Adv. 2019 Dec 23;3(24):4215-4227. doi: 10.1182/bloodadvances.2019000499.

3.

Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity.

Kitakaze K, Taniuchi S, Kawano E, Hamada Y, Miyake M, Oyadomari M, Kojima H, Kosako H, Kuribara T, Yoshida S, Hosoya T, Oyadomari S.

Elife. 2019 Dec 17;8. pii: e43302. doi: 10.7554/eLife.43302.

4.

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR.

Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte JS, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P, Marot G, Boulter A, Tavernier S, Berod L, Longhi MP, Paget C, Janssens S, Staumont-Sallé D, Aksoy E, Staels B, Dombrowicz D.

Cell. 2019 Jun 27;178(1):263. doi: 10.1016/j.cell.2019.06.017. No abstract available.

PMID:
31251916
5.

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR.

Mogilenko DA, Haas JT, L'homme L, Fleury S, Quemener S, Levavasseur M, Becquart C, Wartelle J, Bogomolova A, Pineau L, Molendi-Coste O, Lancel S, Dehondt H, Gheeraert C, Melchior A, Dewas C, Nikitin A, Pic S, Rabhi N, Annicotte JS, Oyadomari S, Velasco-Hernandez T, Cammenga J, Foretz M, Viollet B, Vukovic M, Villacreces A, Kranc K, Carmeliet P, Marot G, Boulter A, Tavernier S, Berod L, Longhi MP, Paget C, Janssens S, Staumont-Sallé D, Aksoy E, Staels B, Dombrowicz D.

Cell. 2019 May 16;177(5):1201-1216.e19. doi: 10.1016/j.cell.2019.03.018. Epub 2019 Apr 25. Erratum in: Cell. 2019 Jun 27;178(1):263.

6.

Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes.

Mimura J, Inose-Maruyama A, Taniuchi S, Kosaka K, Yoshida H, Yamazaki H, Kasai S, Harada N, Kaufman RJ, Oyadomari S, Itoh K.

Int J Mol Sci. 2019 Apr 5;20(7). pii: E1706. doi: 10.3390/ijms20071706.

7.

Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine.

Hashimoto O, Funaba M, Sekiyama K, Doi S, Shindo D, Satoh R, Itoi H, Oiwa H, Morita M, Suzuki C, Sugiyama M, Yamakawa N, Takada H, Matsumura S, Inoue K, Oyadomari S, Sugino H, Kurisaki A.

Cell Rep. 2018 Oct 30;25(5):1193-1203. doi: 10.1016/j.celrep.2018.10.008.

8.

[Inter-Organ Metabolic Communication via the Unfolded Stress Response.]

Miyake M, Oyadomari S.

Clin Calcium. 2018;28(11):1548-1553. doi: CliCa181115481553. Japanese.

PMID:
30374012
9.

PERK-mediated translational control is required for collagen secretion in chondrocytes.

Hisanaga S, Miyake M, Taniuchi S, Oyadomari M, Morimoto M, Sato R, Hirose J, Mizuta H, Oyadomari S.

Sci Rep. 2018 Jan 15;8(1):773. doi: 10.1038/s41598-017-19052-9.

10.

A miR-327-FGF10-FGFR2-mediated autocrine signaling mechanism controls white fat browning.

Fischer C, Seki T, Lim S, Nakamura M, Andersson P, Yang Y, Honek J, Wang Y, Gao Y, Chen F, Samani NJ, Zhang J, Miyake M, Oyadomari S, Yasue A, Li X, Zhang Y, Liu Y, Cao Y.

Nat Commun. 2017 Dec 12;8(1):2079. doi: 10.1038/s41467-017-02158-z.

11.

Ligand-induced rapid skeletal muscle atrophy in HSA-Fv2E-PERK transgenic mice.

Miyake M, Kuroda M, Kiyonari H, Takehana K, Hisanaga S, Morimoto M, Zhang J, Oyadomari M, Sakaue H, Oyadomari S.

PLoS One. 2017 Jun 23;12(6):e0179955. doi: 10.1371/journal.pone.0179955. eCollection 2017.

12.

The Role of Heparin Cofactor Ⅱ in the Regulation of Insulin Sensitivity and Maintenance of Glucose Homeostasis in Humans and Mice.

Kurahashi K, Inoue S, Yoshida S, Ikeda Y, Morimoto K, Uemoto R, Ishikawa K, Kondo T, Yuasa T, Endo I, Miyake M, Oyadomari S, Matsumoto T, Abe M, Sakaue H, Aihara KI.

J Atheroscler Thromb. 2017 Dec 1;24(12):1215-1230. doi: 10.5551/jat.37739. Epub 2017 May 15.

13.

Relationship between somatic mosaicism of Pax6 mutation and variable developmental eye abnormalities-an analysis of CRISPR genome-edited mouse embryos.

Yasue A, Kono H, Habuta M, Bando T, Sato K, Inoue J, Oyadomari S, Noji S, Tanaka E, Ohuchi H.

Sci Rep. 2017 Mar 3;7(1):53. doi: 10.1038/s41598-017-00088-w.

14.

ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity.

Suzuki T, Gao J, Ishigaki Y, Kondo K, Sawada S, Izumi T, Uno K, Kaneko K, Tsukita S, Takahashi K, Asao A, Ishii N, Imai J, Yamada T, Oyadomari S, Katagiri H.

Cell Rep. 2017 Feb 21;18(8):2045-2057. doi: 10.1016/j.celrep.2017.01.076.

15.

Novel human mutation and CRISPR/Cas genome-edited mice reveal the importance of C-terminal domain of MSX1 in tooth and palate development.

Mitsui SN, Yasue A, Masuda K, Naruto T, Minegishi Y, Oyadomari S, Noji S, Imoto I, Tanaka E.

Sci Rep. 2016 Dec 5;6:38398. doi: 10.1038/srep38398.

16.

Integrated stress response of vertebrates is regulated by four eIF2α kinases.

Taniuchi S, Miyake M, Tsugawa K, Oyadomari M, Oyadomari S.

Sci Rep. 2016 Sep 16;6:32886. doi: 10.1038/srep32886.

17.

Correction: Long-Term Low Carbohydrate Diet Leads to Deleterious Metabolic Manifestations in Diabetic Mice.

Handa K, Inukai K, Onuma H, Kudo A, Nakagawa F, Tsugawa K, Kitahara A, Moriya R, Takahashi K, Sumitani Y, Hosaka T, Kawakami H, Oyadomari S, Ishida H.

PLoS One. 2016 May 16;11(5):e0155751. doi: 10.1371/journal.pone.0155751. eCollection 2016.

18.

Use of a modified early warning score system to reduce the rate of in-hospital cardiac arrest.

Nishijima I, Oyadomari S, Maedomari S, Toma R, Igei C, Kobata S, Koyama J, Tomori R, Kawamitsu N, Yamamoto Y, Tsuchida M, Tokeshi Y, Ikemura R, Miyagi K, Okiyama K, Iha K.

J Intensive Care. 2016 Feb 9;4:12. doi: 10.1186/s40560-016-0134-7. eCollection 2016.

19.

Unfolded protein response in hypothalamic cultures of wild-type and ATF6α-knockout mice.

Lu W, Hagiwara D, Morishita Y, Tochiya M, Azuma Y, Suga H, Goto M, Banno R, Sugimura Y, Oyadomari S, Mori K, Arima H.

Neurosci Lett. 2016 Jan 26;612:199-203. doi: 10.1016/j.neulet.2015.12.031. Epub 2015 Dec 18.

PMID:
26708632
20.

Skeletal muscle-specific eukaryotic translation initiation factor 2α phosphorylation controls amino acid metabolism and fibroblast growth factor 21-mediated non-cell-autonomous energy metabolism.

Miyake M, Nomura A, Ogura A, Takehana K, Kitahara Y, Takahara K, Tsugawa K, Miyamoto C, Miura N, Sato R, Kurahashi K, Harding HP, Oyadomari M, Ron D, Oyadomari S.

FASEB J. 2016 Feb;30(2):798-812. doi: 10.1096/fj.15-275990. Epub 2015 Oct 20.

21.

A novel insulinotropic mechanism of whole grain-derived γ-oryzanol via the suppression of local dopamine D2 receptor signalling in mouse islet.

Kozuka C, Sunagawa S, Ueda R, Higa M, Ohshiro Y, Tanaka H, Shimizu-Okabe C, Takayama C, Matsushita M, Tsutsui M, Ishiuchi S, Nakata M, Yada T, Miyazaki JI, Oyadomari S, Shimabukuro M, Masuzaki H.

Br J Pharmacol. 2015 Sep;172(18):4519-4534. doi: 10.1111/bph.13236. Epub 2015 Aug 3.

22.

γ-Oryzanol protects pancreatic β-cells against endoplasmic reticulum stress in male mice.

Kozuka C, Sunagawa S, Ueda R, Higa M, Tanaka H, Shimizu-Okabe C, Ishiuchi S, Takayama C, Matsushita M, Tsutsui M, Miyazaki J, Oyadomari S, Shimabukuro M, Masuzaki H.

Endocrinology. 2015 Apr;156(4):1242-50. doi: 10.1210/en.2014-1748. Epub 2015 Jan 16.

PMID:
25594697
23.

Growth arrest and DNA damage-inducible 34 regulates liver regeneration in hepatic steatosis in mice.

Inaba Y, Furutani T, Kimura K, Watanabe H, Haga S, Kido Y, Matsumoto M, Yamamoto Y, Harada K, Kaneko S, Oyadomari S, Ozaki M, Kasuga M, Inoue H.

Hepatology. 2015 Apr;61(4):1343-56. doi: 10.1002/hep.27619. Epub 2015 Feb 23.

PMID:
25420998
24.

Activating transcription factor 6α is required for the vasopressin neuron system to maintain water balance under dehydration in male mice.

Azuma Y, Hagiwara D, Lu W, Morishita Y, Suga H, Goto M, Banno R, Sugimura Y, Oyadomari S, Mori K, Shiota A, Asai N, Takahashi M, Oiso Y, Arima H.

Endocrinology. 2014 Dec;155(12):4905-14. doi: 10.1210/en.2014-1522. Epub 2014 Sep 9.

PMID:
25203138
25.

Palmitate-stimulated monocytes induce adhesion molecule expression in endothelial cells via IL-1 signaling pathway.

Shikama Y, Aki N, Hata A, Nishimura M, Oyadomari S, Funaki M.

J Cell Physiol. 2015 Mar;230(3):732-42. doi: 10.1002/jcp.24797.

PMID:
25201247
26.

Long-term low carbohydrate diet leads to deleterious metabolic manifestations in diabetic mice.

Handa K, Inukai K, Onuma H, Kudo A, Nakagawa F, Tsugawa K, Kitahara A, Moriya R, Takahashi K, Sumitani Y, Hosaka T, Kawakami H, Oyadomari S, Ishida H.

PLoS One. 2014 Aug 29;9(8):e104948. doi: 10.1371/journal.pone.0104948. eCollection 2014. Erratum in: PLoS One. 2016;11(5):e0155751.

27.

Highly efficient targeted mutagenesis in one-cell mouse embryos mediated by the TALEN and CRISPR/Cas systems.

Yasue A, Mitsui SN, Watanabe T, Sakuma T, Oyadomari S, Yamamoto T, Noji S, Mito T, Tanaka E.

Sci Rep. 2014 Jul 16;4:5705. doi: 10.1038/srep05705.

28.

Endoplasmic reticulum stress-induced apoptosis contributes to articular cartilage degeneration via C/EBP homologous protein.

Uehara Y, Hirose J, Yamabe S, Okamoto N, Okada T, Oyadomari S, Mizuta H.

Osteoarthritis Cartilage. 2014 Jul;22(7):1007-17. doi: 10.1016/j.joca.2014.04.025. Epub 2014 May 2.

29.

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome.

Yoshimoto S, Loo TM, Atarashi K, Kanda H, Sato S, Oyadomari S, Iwakura Y, Oshima K, Morita H, Hattori M, Honda K, Ishikawa Y, Hara E, Ohtani N.

Nature. 2013 Jul 4;499(7456):97-101. doi: 10.1038/nature12347. Epub 2013 Jun 26. Erratum in: Nature. 2014 Feb 20;506(7488):396. Hattori, Masahisa [corrected to Hattori, Masahira].

PMID:
23803760
30.

Brown rice and its component, γ-oryzanol, attenuate the preference for high-fat diet by decreasing hypothalamic endoplasmic reticulum stress in mice.

Kozuka C, Yabiku K, Sunagawa S, Ueda R, Taira S, Ohshiro H, Ikema T, Yamakawa K, Higa M, Tanaka H, Takayama C, Matsushita M, Oyadomari S, Shimabukuro M, Masuzaki H.

Diabetes. 2012 Dec;61(12):3084-93. doi: 10.2337/db11-1767. Epub 2012 Jul 23.

31.

Nanosecond pulsed electric fields act as a novel cellular stress that induces translational suppression accompanied by eIF2α phosphorylation and 4E-BP1 dephosphorylation.

Morotomi-Yano K, Oyadomari S, Akiyama H, Yano K.

Exp Cell Res. 2012 Aug 15;318(14):1733-44. doi: 10.1016/j.yexcr.2012.04.016. Epub 2012 May 28.

PMID:
22652449
32.

Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism.

Birkenfeld AL, Lee HY, Majumdar S, Jurczak MJ, Camporez JP, Jornayvaz FR, Frederick DW, Guigni B, Kahn M, Zhang D, Weismann D, Arafat AM, Pfeiffer AF, Lieske S, Oyadomari S, Ron D, Samuel VT, Shulman GI.

J Biol Chem. 2011 Oct 21;286(42):36163-70. doi: 10.1074/jbc.M111.228817. Epub 2011 Aug 5.

33.

Involvement of endoplasmic stress protein C/EBP homologous protein in arteriosclerosis acceleration with augmented biological stress responses.

Gao J, Ishigaki Y, Yamada T, Kondo K, Yamaguchi S, Imai J, Uno K, Hasegawa Y, Sawada S, Ishihara H, Oyadomari S, Mori M, Oka Y, Katagiri H.

Circulation. 2011 Aug 16;124(7):830-9. doi: 10.1161/CIRCULATIONAHA.110.014050. Epub 2011 Aug 1.

PMID:
21810656
34.

CHOP deletion does not impact the development of diabetes but suppresses the early production of insulin autoantibody in the NOD mouse.

Satoh T, Abiru N, Kobayashi M, Zhou H, Nakamura K, Kuriya G, Nakamura H, Nagayama Y, Kawasaki E, Yamasaki H, Yu L, Eisenbarth GS, Araki E, Mori M, Oyadomari S, Eguchi K.

Apoptosis. 2011 Apr;16(4):438-48. doi: 10.1007/s10495-011-0576-2.

PMID:
21274633
35.

Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress.

Yamamoto K, Takahara K, Oyadomari S, Okada T, Sato T, Harada A, Mori K.

Mol Biol Cell. 2010 Sep 1;21(17):2975-86. doi: 10.1091/mbc.E09-02-0133. Epub 2010 Jul 14.

36.

The role of CHOP messenger RNA expression in the link between oxidative stress and apoptosis.

Ariyama Y, Tanaka Y, Shimizu H, Shimomura K, Okada S, Saito T, Yamada E, Oyadomari S, Mori M, Mori M.

Metabolism. 2008 Dec;57(12):1625-35. doi: 10.1016/j.metabol.2008.06.019.

PMID:
19013284
37.

Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3.

Petrova K, Oyadomari S, Hendershot LM, Ron D.

EMBO J. 2008 Nov 5;27(21):2862-72. doi: 10.1038/emboj.2008.199. Epub 2008 Oct 16.

38.

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice.

Oyadomari S, Harding HP, Zhang Y, Oyadomari M, Ron D.

Cell Metab. 2008 Jun;7(6):520-32. doi: 10.1016/j.cmet.2008.04.011.

39.

Chop-deficient mice showed increased adiposity but no glucose intolerance.

Ariyama Y, Shimizu H, Satoh T, Tsuchiya T, Okada S, Oyadomari S, Mori M, Mori M.

Obesity (Silver Spring). 2007 Jul;15(7):1647-56.

40.

Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload.

Oyadomari S, Yun C, Fisher EA, Kreglinger N, Kreibich G, Oyadomari M, Harding HP, Goodman AG, Harant H, Garrison JL, Taunton J, Katze MG, Ron D.

Cell. 2006 Aug 25;126(4):727-39. Erratum in: Cell. 2006 Dec 16;127(6):1284.

41.

The ER stress pathway involving CHOP is activated in the lungs of LPS-treated mice.

Endo M, Oyadomari S, Suga M, Mori M, Gotoh T.

J Biochem. 2005 Oct;138(4):501-7.

PMID:
16272146
42.

NMDA-induced retinal injury is mediated by an endoplasmic reticulum stress-related protein, CHOP/GADD153.

Awai M, Koga T, Inomata Y, Oyadomari S, Gotoh T, Mori M, Tanihara H.

J Neurochem. 2006 Jan;96(1):43-52. Epub 2005 Nov 3.

43.

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.

Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, Jungreis R, Nagata K, Harding HP, Ron D.

Genes Dev. 2004 Dec 15;18(24):3066-77.

44.

Lipid phase perturbations and the unfolded protein response.

Ron D, Oyadomari S.

Dev Cell. 2004 Sep;7(3):287-8.

45.

Induction of molecular chaperones in carbon tetrachloride-treated rat liver: implications in protection against liver damage.

Lee KJ, Terada K, Oyadomari S, Inomata Y, Mori M, Gotoh T.

Cell Stress Chaperones. 2004 Mar;9(1):58-68.

46.
47.

Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP.

Tajiri S, Oyadomari S, Yano S, Morioka M, Gotoh T, Hamada JI, Ushio Y, Mori M.

Cell Death Differ. 2004 Apr;11(4):403-15.

48.

Roles of CHOP/GADD153 in endoplasmic reticulum stress.

Oyadomari S, Mori M.

Cell Death Differ. 2004 Apr;11(4):381-9. Review.

49.

Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells.

Jousse C, Oyadomari S, Novoa I, Lu P, Zhang Y, Harding HP, Ron D.

J Cell Biol. 2003 Nov 24;163(4):767-75.

50.

[Diabetes mellitus and endoplasmic reticulum stress].

Araki E, Oyadomari S, Mori M.

Seikagaku. 2003 Oct;75(10):1324-31. Review. Japanese. No abstract available.

PMID:
14635524

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