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Items: 1 to 50 of 181

1.

Mapping the drivers of within-host pathogen evolution using massive data sets.

Palmer DS, Turner I, Fidler S, Frater J, Goedhals D, Goulder P, Huang KG, Oxenius A, Phillips R, Shapiro R, Vuuren CV, McLean AR, McVean G.

Nat Commun. 2019 Jul 9;10(1):3017. doi: 10.1038/s41467-019-10724-w.

2.

Investigating the Dynamics of MCMV-Specific CD8+ T Cell Responses in Individual Hosts.

Gabel M, Baumann NS, Oxenius A, Graw F.

Front Immunol. 2019 Jun 19;10:1358. doi: 10.3389/fimmu.2019.01358. eCollection 2019.

3.

Early primed KLRG1- CMV-specific T cells determine the size of the inflationary T cell pool.

Baumann NS, Welten SPM, Torti N, Pallmer K, Borsa M, Barnstorf I, Oduro JD, Cicin-Sain L, Oxenius A.

PLoS Pathog. 2019 May 13;15(5):e1007785. doi: 10.1371/journal.ppat.1007785. eCollection 2019 May.

4.

Two sequential layers of antibody-mediated control of Legionella pneumophila infection.

Weber SS, Stoycheva D, Nimmerjahn F, Oxenius A.

Eur J Immunol. 2019 May 10. doi: 10.1002/eji.201948106. [Epub ahead of print]

PMID:
31074841
5.

Right and Left Ventricular Strain Patterns After the Atrial Switch Operation for D-Transposition of the Great Arteries-A Magnetic Resonance Feature Tracking Study.

Burkhardt BEU, Kellenberger CJ, Franzoso FD, Geiger J, Oxenius A, Valsangiacomo Buechel ER.

Front Cardiovasc Med. 2019 Apr 9;6:39. doi: 10.3389/fcvm.2019.00039. eCollection 2019.

6.

NK cells negatively regulate CD8 T cells via natural cytotoxicity receptor (NCR) 1 during LCMV infection.

Pallmer K, Barnstorf I, Baumann NS, Borsa M, Jonjic S, Oxenius A.

PLoS Pathog. 2019 Apr 17;15(4):e1007725. doi: 10.1371/journal.ppat.1007725. eCollection 2019 Apr.

7.

Modulation of asymmetric cell division as a mechanism to boost CD8+ T cell memory.

Borsa M, Barnstorf I, Baumann NS, Pallmer K, Yermanos A, Gräbnitz F, Barandun N, Hausmann A, Sandu I, Barral Y, Oxenius A.

Sci Immunol. 2019 Apr 12;4(34). pii: eaav1730. doi: 10.1126/sciimmunol.aav1730.

PMID:
30979796
8.

Fuel and brake of memory T cell inflation.

Welten SPM, Baumann NS, Oxenius A.

Med Microbiol Immunol. 2019 Aug;208(3-4):329-338. doi: 10.1007/s00430-019-00587-9. Epub 2019 Mar 9. Review.

PMID:
30852648
9.

MHC class II proteins mediate cross-species entry of bat influenza viruses.

Karakus U, Thamamongood T, Ciminski K, Ran W, Günther SC, Pohl MO, Eletto D, Jeney C, Hoffmann D, Reiche S, Schinköthe J, Ulrich R, Wiener J, Hayes MGB, Chang MW, Hunziker A, Yángüez E, Aydillo T, Krammer F, Oderbolz J, Meier M, Oxenius A, Halenius A, Zimmer G, Benner C, Hale BG, García-Sastre A, Beer M, Schwemmle M, Stertz S.

Nature. 2019 Mar;567(7746):109-112. doi: 10.1038/s41586-019-0955-3. Epub 2019 Feb 20.

PMID:
30787439
10.

Chronic virus infection compromises memory bystander T cell function in an IL-6/STAT1-dependent manner.

Barnstorf I, Borsa M, Baumann N, Pallmer K, Yermanos A, Joller N, Spörri R, Welten SPM, Kräutler NJ, Oxenius A.

J Exp Med. 2019 Mar 4;216(3):571-586. doi: 10.1084/jem.20181589. Epub 2019 Feb 11.

PMID:
30745322
11.

Tracing Antibody Repertoire Evolution by Systems Phylogeny.

Yermanos AD, Dounas AK, Stadler T, Oxenius A, Reddy ST.

Front Immunol. 2018 Oct 2;9:2149. doi: 10.3389/fimmu.2018.02149. eCollection 2018. Review.

12.

Predictors of quality of life in young adults with congenital heart disease.

Rometsch S, Greutmann M, Latal B, Bernaschina I, Knirsch W, Schaefer C, Oxenius A, Landolt MA.

Eur Heart J Qual Care Clin Outcomes. 2019 Apr 1;5(2):161-168. doi: 10.1093/ehjqcco/qcy046.

PMID:
30239653
13.

The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity.

Castro W, Chelbi ST, Niogret C, Ramon-Barros C, Welten SPM, Osterheld K, Wang H, Rota G, Morgado L, Vivier E, Raeber ME, Boyman O, Delorenzi M, Barras D, Ho PC, Oxenius A, Guarda G.

Nat Immunol. 2018 Aug;19(8):809-820. doi: 10.1038/s41590-018-0144-9. Epub 2018 Jul 2.

14.

The Janus Face of Follicular T Helper Cells in Chronic Viral Infections.

Greczmiel U, Oxenius A.

Front Immunol. 2018 May 25;9:1162. doi: 10.3389/fimmu.2018.01162. eCollection 2018. Review.

15.

Memory CD8 T cell inflation vs tissue-resident memory T cells: Same patrollers, same controllers?

Welten SPM, Sandu I, Baumann NS, Oxenius A.

Immunol Rev. 2018 May;283(1):161-175. doi: 10.1111/imr.12649. Review.

PMID:
29664565
16.

Tissue maintenance of CMV-specific inflationary memory T cells by IL-15.

Baumann NS, Torti N, Welten SPM, Barnstorf I, Borsa M, Pallmer K, Oduro JD, Cicin-Sain L, Ikuta K, Ludewig B, Oxenius A.

PLoS Pathog. 2018 Apr 13;14(4):e1006993. doi: 10.1371/journal.ppat.1006993. eCollection 2018 Apr.

17.

Brain-resident memory CD8+ T cells induced by congenital CMV infection prevent brain pathology and virus reactivation.

Brizić I, Šušak B, Arapović M, Huszthy PC, Hiršl L, Kveštak D, Juranić Lisnić V, Golemac M, Pernjak Pugel E, Tomac J, Oxenius A, Britt WJ, Arapović J, Krmpotić A, Jonjić S.

Eur J Immunol. 2018 Jun;48(6):950-964. doi: 10.1002/eji.201847526. Epub 2018 Mar 23.

18.

Sustained T follicular helper cell response is essential for control of chronic viral infection.

Greczmiel U, Kräutler NJ, Pedrioli A, Bartsch I, Agnellini P, Bedenikovic G, Harker J, Richter K, Oxenius A.

Sci Immunol. 2017 Dec 1;2(18). pii: eaam8686. doi: 10.1126/sciimmunol.aam8686.

19.

Swiss Adult Congenital HEart disease Registry (SACHER) - rationale, design and first results.

Tobler D, Schwerzmann M, Bouchardy J, Engel R, Stambach D, Attenhofer Jost C, Wustmann K, Schwitz F, Rutz T, Gabriel H, Kuen HP, Auf der Maur C, Oxenius A, Seeliger T, Santos Lopes B, Bonassin F, Greutmann M, On Behalf Of Sacher.

Swiss Med Wkly. 2017 Oct 27;147:w14519. doi: 10.4414/smw.2017.14519. eCollection 2017.

20.

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Cossarizza A, Chang HD, Radbruch A, Akdis M, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais PE, Brinkman RR, Büscher M, Busch DH, Bushnell TP, Cao X, Cavani A, Chattopadhyay PK, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang VD, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg VS, Dörner T, Ehrhardt GRA, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Dreher A, Falk CS, Fehniger TA, Filby A, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frenette PS, Galbraith D, Garbi N, García-Godoy MD, Geginat J, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear CS, Gori A, Grogan J, Gross M, Grützkau A, Grummitt D, Hahn J, Hammer Q, Hauser AE, Haviland DL, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston JP, Hoyer BF, Huang B, Hunter CA, Iannone A, Jäck HM, Jávega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhöfer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold MD, Levings MK, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker HT, Martrus G, Matarese G, Maueröder C, McGrath M, McInnes I, Mei HE, Melchers F, Melzer S, Mielenz D, Mills K, Mirrer D, Mjösberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann TR, Müller S, Müller W, Münz C, Multhoff G, Munoz LE, Murphy KM, Nakayama T, Nasi M, Neudörfl C, Nolan J, Nourshargh S, O'Connor JE, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley AG, Podolska MJ, Pucillo C, Quataert SA, Radstake TRDJ, Rajwa B, Rebhahn JA, Recktenwald D, Remmerswaal EBM, Rezvani K, Rico LG, Robinson JP, Romagnani C, Rubartelli A, Ruckert B, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid SA, Schmitt S, Schober K, Schüler T, Schulz AR, Schumacher T, Scotta C, Shankey TV, Shemer A, Simon AK, Spidlen J, Stall AM, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Volkmann K, Waisman A, Walker R, Ward MD, Warnatz K, Warth S, Watson JV, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J.

Eur J Immunol. 2017 Oct;47(10):1584-1797. doi: 10.1002/eji.201646632. No abstract available.

21.

Comparison of methods for phylogenetic B-cell lineage inference using time-resolved antibody repertoire simulations (AbSim).

Yermanos A, Greiff V, Krautler NJ, Menzel U, Dounas A, Miho E, Oxenius A, Stadler T, Reddy ST.

Bioinformatics. 2017 Dec 15;33(24):3938-3946. doi: 10.1093/bioinformatics/btx533.

PMID:
28968873
22.

Impact of growing cohorts of adults with con-genital heart disease on clinical workload: a 20-year experience at a tertiary care centre.

Padrutt M, Bracher I, Bonassin F, Santos Lopes B, Gruner C, Stämpfli SF, Wolber T, Kretschmar O, Oxenius A, De Pasquale G, Seeliger T, Lüscher TF, Attenhofer Jost C, Greutmann M.

Swiss Med Wkly. 2017 May 10;147:w14443. doi: 10.4414/smw.2017.14443. eCollection 2017.

23.

Burden and impact of congenital syndromes and comorbidities among adults with congenital heart disease.

Bracher I, Padrutt M, Bonassin F, Santos Lopes B, Gruner C, Stämpfli SF, Oxenius A, De Pasquale G, Seeliger T, Lüscher TF, Attenhofer Jost C, Greutmann M.

Int J Cardiol. 2017 Aug 1;240:159-164. doi: 10.1016/j.ijcard.2017.02.118.

PMID:
28606676
24.

Sarcoma Eradication by Doxorubicin and Targeted TNF Relies upon CD8+ T-cell Recognition of a Retroviral Antigen.

Probst P, Kopp J, Oxenius A, Colombo MP, Ritz D, Fugmann T, Neri D.

Cancer Res. 2017 Jul 1;77(13):3644-3654. doi: 10.1158/0008-5472.CAN-16-2946. Epub 2017 May 8.

25.

High prevalence of baffle leaks in adults after atrial switch operations for transposition of the great arteries.

De Pasquale G, Bonassin Tempesta F, Lopes BS, Babic D, Oxenius A, Seeliger T, Gruner C, Tanner FC, Biaggi P, Attenhofer Jost C, Greutmann M.

Eur Heart J Cardiovasc Imaging. 2017 May 1;18(5):531-535. doi: 10.1093/ehjci/jew276.

26.

Recognition and Regulation of T Cells by NK Cells.

Pallmer K, Oxenius A.

Front Immunol. 2016 Jun 24;7:251. doi: 10.3389/fimmu.2016.00251. eCollection 2016. Review.

27.

Dendritic cells primed with a chimeric plasmid containing HIV-1-gag associated with lysosomal-associated protein-1 (LAMP/gag) is a potential therapeutic vaccine against HIV.

Lucas CG, Matassoli FL, Peçanha LM, Santillo BT, Oliveira LM, Oshiro TM, Marques ET Jr, Oxenius A, de Arruda LB.

FASEB J. 2016 Aug;30(8):2970-84. doi: 10.1096/fj.201500059. Epub 2016 May 19.

PMID:
27199296
28.

T cell responses to cytomegalovirus.

Klenerman P, Oxenius A.

Nat Rev Immunol. 2016 Jun;16(6):367-77. doi: 10.1038/nri.2016.38. Epub 2016 Apr 25. Review.

PMID:
27108521
29.

Neutrophil and Alveolar Macrophage-Mediated Innate Immune Control of Legionella pneumophila Lung Infection via TNF and ROS.

Ziltener P, Reinheckel T, Oxenius A.

PLoS Pathog. 2016 Apr 22;12(4):e1005591. doi: 10.1371/journal.ppat.1005591. eCollection 2016 Apr.

30.

Tumor-necrosis factor impairs CD4(+) T cell-mediated immunological control in chronic viral infection.

Beyer M, Abdullah Z, Chemnitz JM, Maisel D, Sander J, Lehmann C, Thabet Y, Shinde PV, Schmidleithner L, Köhne M, Trebicka J, Schierwagen R, Hofmann A, Popov A, Lang KS, Oxenius A, Buch T, Kurts C, Heikenwalder M, Fätkenheuer G, Lang PA, Hartmann P, Knolle PA, Schultze JL.

Nat Immunol. 2016 May;17(5):593-603. doi: 10.1038/ni.3399. Epub 2016 Mar 7.

PMID:
26950238
31.

Tissue-resident memory T cells in cytomegalovirus infection.

Thom JT, Oxenius A.

Curr Opin Virol. 2016 Feb;16:63-69. doi: 10.1016/j.coviro.2016.01.014. Epub 2016 Feb 12. Review.

PMID:
26855038
32.

Atrial Function after the Atrial Switch Operation for Transposition of the Great Arteries: Comparison with Arterial Switch and Normals by Cardiovascular Magnetic Resonance.

Franzoso FD, Wohlmuth C, Greutmann M, Kellenberger CJ, Oxenius A, Voser EM, Valsangiacomo Buechel ER.

Congenit Heart Dis. 2016 Sep;11(5):426-436. doi: 10.1111/chd.12323. Epub 2015 Dec 18.

PMID:
26680275
33.

The Salivary Gland Acts as a Sink for Tissue-Resident Memory CD8(+) T Cells, Facilitating Protection from Local Cytomegalovirus Infection.

Thom JT, Weber TC, Walton SM, Torti N, Oxenius A.

Cell Rep. 2015 Nov 10;13(6):1125-1136. doi: 10.1016/j.celrep.2015.09.082. Epub 2015 Oct 29.

34.

Gut commensal microbes do not represent a dominant antigenic source for continuous CD4+ T-cell activation during HIV-1 infection.

Zimmermann K, Bastidas S, Knecht L, Kuster H, Vavricka SR, Günthard HF, Oxenius A.

Eur J Immunol. 2015 Nov;45(11):3107-13. doi: 10.1002/eji.201545940. Epub 2015 Oct 23.

35.

Estimating the In Vivo Killing Efficacy of Cytotoxic T Lymphocytes across Different Peptide-MHC Complex Densities.

Garcia V, Richter K, Graw F, Oxenius A, Regoes RR.

PLoS Comput Biol. 2015 May 1;11(5):e1004178. doi: 10.1371/journal.pcbi.1004178. eCollection 2015 May.

36.

T cell metabolism. The protein LEM promotes CD8⁺ T cell immunity through effects on mitochondrial respiration.

Okoye I, Wang L, Pallmer K, Richter K, Ichimura T, Haas R, Crouse J, Choi O, Heathcote D, Lovo E, Mauro C, Abdi R, Oxenius A, Rutschmann S, Ashton-Rickardt PG.

Science. 2015 May 29;348(6238):995-1001. doi: 10.1126/science.aaa7516. Epub 2015 Apr 16. Erratum in: Science. 2015 Oct 23;350(6259):aad6462. Retraction in: Science. 2016 Dec 16;354(6318):1385.

37.

Regulation of antiviral T cell responses by type I interferons.

Crouse J, Kalinke U, Oxenius A.

Nat Rev Immunol. 2015 Apr;15(4):231-42. doi: 10.1038/nri3806. Epub 2015 Mar 20. Review.

PMID:
25790790
38.

The orientation of HIV-1 gp120 binding to the CD4 receptor differentially modulates CD4+ T cell activation.

Zimmermann K, Liechti T, Haas A, Rehr M, Trkola A, Günthard HF, Oxenius A.

J Immunol. 2015 Jan 15;194(2):637-49. doi: 10.4049/jimmunol.1401863. Epub 2014 Dec 3.

39.

NK cells regulating T cell responses: mechanisms and outcome.

Crouse J, Xu HC, Lang PA, Oxenius A.

Trends Immunol. 2015 Jan;36(1):49-58. Review.

PMID:
25432489
40.

Dissecting the contribution of IgG subclasses in restricting airway infection with Legionella pneumophila.

Weber SS, Ducry J, Oxenius A.

J Immunol. 2014 Oct 15;193(8):4053-9. doi: 10.4049/jimmunol.1401031. Epub 2014 Sep 10.

41.

Type I interferons protect T cells against NK cell attack mediated by the activating receptor NCR1.

Crouse J, Bedenikovic G, Wiesel M, Ibberson M, Xenarios I, Von Laer D, Kalinke U, Vivier E, Jonjic S, Oxenius A.

Immunity. 2014 Jun 19;40(6):961-73. doi: 10.1016/j.immuni.2014.05.003. Epub 2014 Jun 5.

42.

VSV-GP: a potent viral vaccine vector that boosts the immune response upon repeated applications.

Tober R, Banki Z, Egerer L, Muik A, Behmüller S, Kreppel F, Greczmiel U, Oxenius A, von Laer D, Kimpel J.

J Virol. 2014 May;88(9):4897-907. doi: 10.1128/JVI.03276-13. Epub 2014 Feb 19.

43.

Medical treatment of aortic aneurysms in Marfan syndrome and other heritable conditions.

Attenhofer Jost CH, Greutmann M, Connolly HM, Weber R, Rohrbach M, Oxenius A, Kretschmar O, Luscher TF, Matyas G.

Curr Cardiol Rev. 2014 May;10(2):161-71. Review.

44.

CD4+ T-cell help is required for effective CD8+ T cell-mediated resolution of acute viral hepatitis in mice.

Trautmann T, Kozik JH, Carambia A, Richter K, Lischke T, Schwinge D, Mittrücker HW, Lohse AW, Oxenius A, Wiegard C, Herkel J.

PLoS One. 2014 Jan 21;9(1):e86348. doi: 10.1371/journal.pone.0086348. eCollection 2014.

45.

TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance.

Weber B, Schuster S, Zysset D, Rihs S, Dickgreber N, Schürch C, Riether C, Siegrist M, Schneider C, Pawelski H, Gurzeler U, Ziltener P, Genitsch V, Tacchini-Cottier F, Ochsenbein A, Hofstetter W, Kopf M, Kaufmann T, Oxenius A, Reith W, Saurer L, Mueller C.

PLoS Pathog. 2014 Jan;10(1):e1003900. doi: 10.1371/journal.ppat.1003900. Epub 2014 Jan 16.

46.

CD8+ T cells are activated in an antigen-independent manner in HIV-infected individuals.

Bastidas S, Graw F, Smith MZ, Kuster H, Günthard HF, Oxenius A.

J Immunol. 2014 Feb 15;192(4):1732-44. doi: 10.4049/jimmunol.1302027. Epub 2014 Jan 20.

47.

Salivary gland resident APCs are Flt3L- and CCR2-independent macrophage-like cells incapable of cross-presentation.

Thom JT, Walton SM, Torti N, Oxenius A.

Eur J Immunol. 2014 Mar;44(3):706-14. doi: 10.1002/eji.201343992. Epub 2013 Dec 23.

48.

Macrophage and T cell produced IL-10 promotes viral chronicity.

Richter K, Perriard G, Behrendt R, Schwendener RA, Sexl V, Dunn R, Kamanaka M, Flavell RA, Roers A, Oxenius A.

PLoS Pathog. 2013;9(11):e1003735. doi: 10.1371/journal.ppat.1003735. Epub 2013 Nov 7.

49.

T-cell help dependence of memory CD8+ T-cell expansion upon vaccinia virus challenge relies on CD40 signaling.

Bedenikovic G, Crouse J, Oxenius A.

Eur J Immunol. 2014 Jan;44(1):115-26. doi: 10.1002/eji.201343805. Epub 2013 Oct 24.

50.

Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ.

Trsan T, Busche A, Abram M, Wensveen FM, Lemmermann NA, Arapovic M, Babic M, Tomic A, Golemac M, Brinkmann MM, Jäger W, Oxenius A, Polic B, Krmpotic A, Messerle M, Jonjic S.

Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16550-5. doi: 10.1073/pnas.1310215110. Epub 2013 Sep 19.

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