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End-of-Life Care, Palliative Care Consultation, and Palliative Care Referral in the Emergency Department: A Systematic Review.

Wilson JG, English DP, Owyang CG, Chimelski EA, Grudzen CR, Wong HN, Aslakson RA; AAHPM Research Committee Writing Group.

J Pain Symptom Manage. 2019 Oct 3. pii: S0885-3924(19)30569-X. doi: 10.1016/j.jpainsymman.2019.09.020. [Epub ahead of print]


Noninvasive Ventilation for Critically Ill Subjects With Acute Respiratory Failure in the Emergency Department.

Goel NN, Owyang C, Ranginwala S, Loo GT, Richardson LD, Mathews KS.

Respir Care. 2019 Oct 1. pii: respcare.07111. doi: 10.4187/respcare.07111. [Epub ahead of print]


High-fat diet-induced vagal afferent dysfunction via upregulation of 2-pore domain potassium TRESK channel.

Grabauskas G, Wu X, Zhou S, Li J, Gao J, Owyang C.

JCI Insight. 2019 Sep 5;4(17). pii: 130402. doi: 10.1172/jci.insight.130402.


Rhinovirus-associated severe acute respiratory distress syndrome (ARDS) managed with airway pressure release ventilation (APRV).

Ayala C, Baiu I, Owyang C, Forrester JD, Spain D.

Trauma Surg Acute Care Open. 2019 Jul 15;4(1):e000322. doi: 10.1136/tsaco-2019-000322. eCollection 2019. No abstract available.


The effect of emergency department crowding on lung-protective ventilation utilization for critically ill patients.

Owyang CG, Kim JL, Loo G, Ranginwala S, Mathews KS.

J Crit Care. 2019 Aug;52:40-47. doi: 10.1016/j.jcrc.2019.03.008. Epub 2019 Mar 23.


Efficacy of Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.

Xu D, Chen VL, Steiner CA, Berinstein JA, Eswaran S, Waljee AK, Higgins PDR, Owyang C.

Am J Gastroenterol. 2019 Jul;114(7):1043-1050. doi: 10.14309/ajg.0000000000000198.


Altered R-spondin 1/CART neurocircuit in the hypothalamus contributes to hyperphagia in diabetes.

Li JY, Wu X, Lee A, Zhou SY, Owyang C.

J Neurophysiol. 2019 Mar 1;121(3):928-939. doi: 10.1152/jn.00413.2018. Epub 2019 Jan 16.


Altered Intestinal Microbiota with Increased Abundance of Prevotella Is Associated with High Risk of Diarrhea-Predominant Irritable Bowel Syndrome.

Su T, Liu R, Lee A, Long Y, Du L, Lai S, Chen X, Wang L, Si J, Owyang C, Chen S.

Gastroenterol Res Pract. 2018 Jun 5;2018:6961783. doi: 10.1155/2018/6961783. eCollection 2018.


FODMAP diet modulates visceral nociception by lipopolysaccharide-mediated intestinal inflammation and barrier dysfunction.

Zhou SY, Gillilland M 3rd, Wu X, Leelasinjaroen P, Zhang G, Zhou H, Ye B, Lu Y, Owyang C.

J Clin Invest. 2018 Jan 2;128(1):267-280. doi: 10.1172/JCI92390. Epub 2017 Nov 27.


Choice of resuscitative fluids and mortality in emergency department patients with sepsis.

Sethi M, Owyang CG, Meyers C, Parekh R, Shah KH, Manini AF.

Am J Emerg Med. 2018 Apr;36(4):625-629. doi: 10.1016/j.ajem.2017.09.042. Epub 2017 Oct 7.


Sugars, Sweet Taste Receptors, and Brain Responses.

Lee AA, Owyang C.

Nutrients. 2017 Jun 24;9(7). pii: E653. doi: 10.3390/nu9070653. Review.


Does Prestroke Antiplatelet Therapy Increase the Risk of Symptomatic Intracranial Hemorrhage in Patients Receiving Tissue Plasminogen Activator for Acute Ischemic Stroke?

Owyang CG, Lay C.

Ann Emerg Med. 2018 Mar;71(3):416-418. doi: 10.1016/j.annemergmed.2017.03.013. Epub 2017 Apr 29. No abstract available.


Plasticity of vagal afferent signaling in the gut.

Grabauskas G, Owyang C.

Medicina (Kaunas). 2017;53(2):73-84. doi: 10.1016/j.medici.2017.03.002. Epub 2017 Apr 10. Review.


East Meets West: The Increasing Incidence of Inflammatory Bowel Disease in Asia as a Paradigm for Environmental Effects on the Pathogenesis of Immune-Mediated Disease.

Yang Y, Owyang C, Wu GD.

Gastroenterology. 2016 Dec;151(6):e1-e5. doi: 10.1053/j.gastro.2016.10.034. Epub 2016 Nov 1. No abstract available.


Increased Activation of the TRESK K+ Mediates Vago-Vagal Reflex Malfunction in Diabetic Rats.

Grabauskas G, Wu X, Song I, Zhou SY, Lanigan T, Owyang C.

Gastroenterology. 2016 Nov;151(5):910-922.e7. doi: 10.1053/j.gastro.2016.07.029. Epub 2016 Jul 27.


Gastroenterology 2011-2016: Looking Back and Forward.

Omary MB, Carethers JM, Owyang C.

Gastroenterology. 2016 Jun;150(7):1496-1502. doi: 10.1053/j.gastro.2016.04.005. No abstract available.


Is Passive Leg Raise an Accurate Diagnostic Method for Assessing Fluid Responsiveness in Adults?

Owyang C, Meyers C.

Ann Emerg Med. 2016 Jul;68(1):103-4. doi: 10.1016/j.annemergmed.2015.11.025. Epub 2016 Jan 30. No abstract available.


Timothy T. Nostrant, MD, MACG, October 20, 1947-October 2, 2015.

Chey WD, Owyang C.

Gastroenterology. 2016 Feb;150(2):289-90. doi: 10.1053/j.gastro.2015.12.028. Epub 2015 Dec 21. No abstract available.


Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine.

Grasberger H, Gao J, Nagao-Kitamoto H, Kitamoto S, Zhang M, Kamada N, Eaton KA, El-Zaatari M, Shreiner AB, Merchant JL, Owyang C, Kao JY.

Gastroenterology. 2015 Dec;149(7):1849-59. doi: 10.1053/j.gastro.2015.07.062. Epub 2015 Aug 7.


KATP channels in the nodose ganglia mediate the orexigenic actions of ghrelin.

Grabauskas G, Wu X, Lu Y, Heldsinger A, Song I, Zhou SY, Owyang C.

J Physiol. 2015 Sep 1;593(17):3973-89. doi: 10.1113/JP270788. Erratum in: J Physiol. 2016 Feb 1;594(3):795.


Are Balanced Crystalloids the Preferred Resuscitation Fluid for Severe Sepsis and Septic Shock?

Owyang CG, Shah KH.

Ann Emerg Med. 2015 Nov;66(5):523-5. doi: 10.1016/j.annemergmed.2015.02.022. Epub 2015 Mar 21. No abstract available.


Upregulation of bile acid receptor TGR5 and nNOS in gastric myenteric plexus is responsible for delayed gastric emptying after chronic high-fat feeding in rats.

Zhou H, Zhou S, Gao J, Zhang G, Lu Y, Owyang C.

Am J Physiol Gastrointest Liver Physiol. 2015 May 15;308(10):G863-73. doi: 10.1152/ajpgi.00380.2014. Epub 2014 Dec 24.


Rifaximin, gut microbes and mucosal inflammation: unraveling a complex relationship.

Gao J, Gillilland MG 3rd, Owyang C.

Gut Microbes. 2014 Jul 1;5(4):571-5. doi: 10.4161/gmic.32130.


Ghrelin induces leptin resistance by activation of suppressor of cytokine signaling 3 expression in male rats: implications in satiety regulation.

Heldsinger A, Grabauskas G, Wu X, Zhou S, Lu Y, Song I, Owyang C.

Endocrinology. 2014 Oct;155(10):3956-69. doi: 10.1210/en.2013-2095. Epub 2014 Jul 25.


The gut microbiome in health and disease.

Owyang C, Wu GD.

Gastroenterology. 2014 May;146(6):1433-6. doi: 10.1053/j.gastro.2014.03.032. Epub 2014 Mar 24. No abstract available.


Challenges of managing pain in constipation-predominant IBS: clinical perspectives on antinociceptive actions of linaclotide.

Hasler WL, Owyang C.

Gastroenterology. 2013 Dec;145(6):1196-9. No abstract available.


Intraluminal acid activates esophageal nodose C fibers after mast cell activation.

Zhang S, Liu Z, Heldsinger A, Owyang C, Yu S.

Am J Physiol Gastrointest Liver Physiol. 2014 Feb;306(3):G200-7. doi: 10.1152/ajpgi.00142.2013. Epub 2013 Nov 21.


Rifaximin alters intestinal bacteria and prevents stress-induced gut inflammation and visceral hyperalgesia in rats.

Xu D, Gao J, Gillilland M 3rd, Wu X, Song I, Kao JY, Owyang C.

Gastroenterology. 2014 Feb;146(2):484-96.e4. doi: 10.1053/j.gastro.2013.10.026. Epub 2013 Oct 22.


Role of prostaglandin D2 in mast cell activation-induced sensitization of esophageal vagal afferents.

Zhang S, Grabauskas G, Wu X, Joo MK, Heldsinger A, Song I, Owyang C, Yu S.

Am J Physiol Gastrointest Liver Physiol. 2013 May 15;304(10):G908-16. doi: 10.1152/ajpgi.00448.2012. Epub 2013 Mar 7.


Stress-induced corticotropin-releasing hormone-mediated NLRP6 inflammasome inhibition and transmissible enteritis in mice.

Sun Y, Zhang M, Chen CC, Gillilland M 3rd, Sun X, El-Zaatari M, Huffnagle GB, Young VB, Zhang J, Hong SC, Chang YM, Gumucio DL, Owyang C, Kao JY.

Gastroenterology. 2013 Jun;144(7):1478-87, 1487.e1-8. doi: 10.1053/j.gastro.2013.02.038. Epub 2013 Mar 5.


Essential elements for glucosensing by gastric vagal afferents: immunocytochemistry and electrophysiology studies in the rat.

Grabauskas G, Zhou SY, Lu Y, Song I, Owyang C.

Endocrinology. 2013 Jan;154(1):296-307. doi: 10.1210/en.2012-1382. Epub 2012 Dec 4.


Cocaine- and amphetamine-regulated transcript is the neurotransmitter regulating the action of cholecystokinin and leptin on short-term satiety in rats.

Heldsinger A, Lu Y, Zhou SY, Wu X, Grabauskas G, Song I, Owyang C.

Am J Physiol Gastrointest Liver Physiol. 2012 Nov 1;303(9):G1042-51. doi: 10.1152/ajpgi.00231.2012. Epub 2012 Aug 30.


Butyrate-induced colonic hypersensitivity is mediated by mitogen-activated protein kinase activation in rat dorsal root ganglia.

Xu D, Wu X, Grabauskas G, Owyang C.

Gut. 2013 Oct;62(10):1466-74. doi: 10.1136/gutjnl-2012-302260. Epub 2012 Jul 24.


Helicobacter pylori DNA's anti-inflammatory effect on experimental colitis.

Owyang SY, Luther J, Owyang CC, Zhang M, Kao JY.

Gut Microbes. 2012 Mar-Apr;3(2):168-71. doi: 10.4161/gmic.19181. Epub 2012 Mar 1. Review.


Vagal control of satiety and hormonal regulation of appetite.

Owyang C, Heldsinger A.

J Neurogastroenterol Motil. 2011 Oct;17(4):338-48. doi: 10.5056/jnm.2011.17.4.338. Epub 2011 Oct 31.


Distraction-induced intestinal enterogenesis: preservation of intestinal function and lengthening after reimplantation into normal jejunum.

Koga H, Sun X, Yang H, Nose K, Somara S, Bitar KN, Owyang C, Okawada M, Teitelbaum DH.

Ann Surg. 2012 Feb;255(2):302-10. doi: 10.1097/SLA.0b013e318233097c.


Phenotypic switching in diabetic gastroparesis: mechanism directs therapy.

Owyang C.

Gastroenterology. 2011 Oct;141(4):1134-7. doi: 10.1053/j.gastro.2011.08.014. Epub 2011 Aug 27. No abstract available.


Diabetic visceral hypersensitivity is associated with activation of mitogen-activated kinase in rat dorsal root ganglia.

Grabauskas G, Heldsinger A, Wu X, Xu D, Zhou S, Owyang C.

Diabetes. 2011 Jun;60(6):1743-51. doi: 10.2337/db10-1507. Epub 2011 Apr 22.


Inhibition of gastric motility by hyperglycemia is mediated by nodose ganglia KATP channels.

Zhou SY, Lu Y, Song I, Owyang C.

Am J Physiol Gastrointest Liver Physiol. 2011 Mar;300(3):G394-400. doi: 10.1152/ajpgi.00493.2010. Epub 2010 Dec 30.


Low-affinity CCK-A receptors are coexpressed with leptin receptors in rat nodose ganglia: implications for leptin as a regulator of short-term satiety.

Li Y, Wu X, Zhou S, Owyang C.

Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G217-27. doi: 10.1152/ajpgi.00356.2010. Epub 2010 Nov 25.


Corticosterone mediates reciprocal changes in CB 1 and TRPV1 receptors in primary sensory neurons in the chronically stressed rat.

Hong S, Zheng G, Wu X, Snider NT, Owyang C, Wiley JW.

Gastroenterology. 2011 Feb;140(2):627-637.e4. doi: 10.1053/j.gastro.2010.11.003. Epub 2010 Nov 9.


Inhibition of acinar apoptosis occurs during acute pancreatitis in the human homologue DeltaF508 cystic fibrosis mouse.

DiMagno MJ, Lee SH, Owyang C, Zhou SY.

Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G400-12. doi: 10.1152/ajpgi.00061.2010. Epub 2010 Jun 3.


Electrophysiological identification of glucose-sensing neurons in rat nodose ganglia.

Grabauskas G, Song I, Zhou S, Owyang C.

J Physiol. 2010 Feb 15;588(Pt 4):617-32. doi: 10.1113/jphysiol.2009.182147. Epub 2009 Dec 14.


Editorial comment: pancreas.

Owyang C.

Curr Opin Gastroenterol. 2009 Sep;25(5):438-40. doi: 10.1097/MOG.0b013e32832ec4db. No abstract available.


Secretin-induced gastric relaxation is mediated by vasoactive intestinal polypeptide and prostaglandin pathways.

Lu Y, Owyang C.

Neurogastroenterol Motil. 2009 Jul;21(7):754-e47. doi: 10.1111/j.1365-2982.2009.01271.x. Epub 2009 Feb 23.


Up-regulation of anterior cingulate cortex NR2B receptors contributes to visceral pain responses in rats.

Fan J, Wu X, Cao Z, Chen S, Owyang C, Li Y.

Gastroenterology. 2009 May;136(5):1732-40.e3. doi: 10.1053/j.gastro.2009.01.069. Epub 2009 Feb 6.



Owyang C.

Curr Opin Gastroenterol. 2008 Sep;24(5):569-72. doi: 10.1097/MOG.0b013e32830bfb71. No abstract available.


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