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Items: 19

1.

Phenotypic Optimization of Urea-Thiophene Carboxamides To Yield Potent, Well Tolerated, and Orally Active Protective Agents against Aminoglycoside-Induced Hearing Loss.

Chowdhury S, Owens KN, Herr RJ, Jiang Q, Chen X, Johnson G, Groppi VE, Raible DW, Rubel EW, Simon JA.

J Med Chem. 2018 Jan 11;61(1):84-97. doi: 10.1021/acs.jmedchem.7b00932. Epub 2017 Oct 27.

2.

Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish.

Stawicki TM, Hernandez L, Esterberg R, Linbo T, Owens KN, Shah AN, Thapa N, Roberts B, Moens CB, Rubel EW, Raible DW.

G3 (Bethesda). 2016 Jul 7;6(7):2225-35. doi: 10.1534/g3.116.030080.

3.

The zebrafish merovingian mutant reveals a role for pH regulation in hair cell toxicity and function.

Stawicki TM, Owens KN, Linbo T, Reinhart KE, Rubel EW, Raible DW.

Dis Model Mech. 2014 Jul;7(7):847-56. doi: 10.1242/dmm.016576.

4.

Loss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephone.

Hailey DW, Roberts B, Owens KN, Stewart AK, Linbo T, Pujol R, Alper SL, Rubel EW, Raible DW.

PLoS Genet. 2012;8(10):e1002971. doi: 10.1371/journal.pgen.1002971. Epub 2012 Oct 11.

5.

Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.

Vlasits AL, Simon JA, Raible DW, Rubel EW, Owens KN.

Hear Res. 2012 Dec;294(1-2):153-65. doi: 10.1016/j.heares.2012.08.002. Epub 2012 Aug 31.

6.

Identification of modulators of hair cell regeneration in the zebrafish lateral line.

Namdaran P, Reinhart KE, Owens KN, Raible DW, Rubel EW.

J Neurosci. 2012 Mar 7;32(10):3516-28. doi: 10.1523/JNEUROSCI.3905-11.2012.

7.

Chemical screening for hair cell loss and protection in the zebrafish lateral line.

Coffin AB, Ou H, Owens KN, Santos F, Simon JA, Rubel EW, Raible DW.

Zebrafish. 2010 Mar;7(1):3-11. doi: 10.1089/zeb.2009.0639. Review.

8.

Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line.

Coffin AB, Reinhart KE, Owens KN, Raible DW, Rubel EW.

Hear Res. 2009 Jul;253(1-2):42-51. doi: 10.1016/j.heares.2009.03.004. Epub 2009 Mar 12.

9.

Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways.

Owens KN, Coffin AB, Hong LS, Bennett KO, Rubel EW, Raible DW.

Hear Res. 2009 Jul;253(1-2):32-41. doi: 10.1016/j.heares.2009.03.001. Epub 2009 Mar 11.

10.

CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290.

Gorden NT, Arts HH, Parisi MA, Coene KL, Letteboer SJ, van Beersum SE, Mans DA, Hikida A, Eckert M, Knutzen D, Alswaid AF, Ozyurek H, Dibooglu S, Otto EA, Liu Y, Davis EE, Hutter CM, Bammler TK, Farin FM, Dorschner M, Top├žu M, Zackai EH, Rosenthal P, Owens KN, Katsanis N, Vincent JB, Hildebrandt F, Rubel EW, Raible DW, Knoers NV, Chance PF, Roepman R, Moens CB, Glass IA, Doherty D.

Am J Hum Genet. 2008 Nov;83(5):559-71. doi: 10.1016/j.ajhg.2008.10.002. Epub 2008 Oct 23.

11.

Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death.

Owens KN, Santos F, Roberts B, Linbo T, Coffin AB, Knisely AJ, Simon JA, Rubel EW, Raible DW.

PLoS Genet. 2008 Feb 29;4(2):e1000020. doi: 10.1371/journal.pgen.1000020.

12.

Ultrastructural analysis of aminoglycoside-induced hair cell death in the zebrafish lateral line reveals an early mitochondrial response.

Owens KN, Cunningham DE, MacDonald G, Rubel EW, Raible DW, Pujol R.

J Comp Neurol. 2007 Jun 1;502(4):522-43.

PMID:
17394157
13.

Genomic sequencing in the service of human rights.

Owens KN, Harvey-Blankenship M, King MC.

Int J Epidemiol. 2002 Feb;31(1):53-8. No abstract available.

PMID:
11914294
14.

Insights into the functions of BRCA1 and BRCA2.

Welcsh PL, Owens KN, King MC.

Trends Genet. 2000 Feb;16(2):69-74. Review.

PMID:
10652533
15.

Paternal effects in Drosophila: implications for mechanisms of early development.

Fitch KR, Yasuda GK, Owens KN, Wakimoto BT.

Curr Top Dev Biol. 1998;38:1-34. Review.

PMID:
9399075
16.

The faint band/interband region 28C2 to 28C4-5(-) of the Drosophila melanogaster salivary gland polytene chromosomes is rich in transcripts.

Friedman TB, Owens KN, Burnett JB, Saura AO, Wallrath LL.

Mol Gen Genet. 1991 Apr;226(1-2):81-7.

PMID:
1903504
17.

Buffalo and bacteria.

Owens KN, Owens SL.

Montana. 1987;37(2):65-7. No abstract available.

PMID:
11617744
18.

"Think yeast"--the expanding spectrum of candidiasis.

Zwerling MH, Owens KN, Ruth NH.

J S C Med Assoc. 1984 Sep;80(9):454-6. No abstract available.

PMID:
6593503
19.

Evaluation of diuril in 50 patients with toxemias of pregnancy.

RIVA HL, HEFNER JD, OWENS KN.

U S Armed Forces Med J. 1959 Apr;10(4):463-7. No abstract available.

PMID:
13635933

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