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Use of a paired-stimulus demand analysis to evaluate demands for inclusion in functional analyses.

Zangrillo AN, Simmons CA, Fisher WW, Owen TM.

J Appl Behav Anal. 2019 Oct 11. doi: 10.1002/jaba.651. [Epub ahead of print]


Protein-Nucleic Acid Conjugation with Sterol Linkers Using Hedgehog Autoprocessing.

Zhang X, Xu Z, Moumin DS, Ciulla DA, Owen TS, Mancusi RA, Giner JL, Wang C, Callahan BP.

Bioconjug Chem. 2019 Oct 10. doi: 10.1021/acs.bioconjchem.9b00550. [Epub ahead of print]


Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease.

Lee EC, Valencia T, Allerson C, Schairer A, Flaten A, Yheskel M, Kersjes K, Li J, Gatto S, Takhar M, Lockton S, Pavlicek A, Kim M, Chu T, Soriano R, Davis S, Androsavich JR, Sarwary S, Owen T, Kaplan J, Liu K, Jang G, Neben S, Bentley P, Wright T, Patel V.

Nat Commun. 2019 Sep 12;10(1):4148. doi: 10.1038/s41467-019-11918-y.


Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies.

Ackland GL, Abbott TEF, Minto G, Clark M, Owen T, Prabhu P, May SM, Reynolds JA, Cuthbertson BH, Wijesundera D, Pearse RM; METS and POM-HR Study Investigators.

PLoS One. 2019 Aug 21;14(8):e0221277. doi: 10.1371/journal.pone.0221277. eCollection 2019.


Use of Observation Status Versus Readmission in Elective Total Knee and Hip Arthroplasty Returns to Hospital: A Single-Institution Perspective.

Goode AE, Owen TM, Moskal JT, Miller TK.

J Arthroplasty. 2019 Oct;34(10):2297-2303.e3. doi: 10.1016/j.arth.2019.05.013. Epub 2019 Jun 19.


Multi-cellularity in cardiac tissue engineering, how close are we to native heart tissue?

Owen TJ, Harding SE.

J Muscle Res Cell Motil. 2019 Jun;40(2):151-157. doi: 10.1007/s10974-019-09528-8. Epub 2019 Jun 20.


How young people are shaping healthcare.

Owen T, Choong L.

BMJ. 2019 Jan 8;364:j5789. doi: 10.1136/sbmj.j5789. No abstract available.


Acceptability of a Plasticity-Focused Serious Game Intervention for Posttraumatic Stress Disorder: User Requirements Analysis.

Jones M, Denisova A, Mitchell S, Owen T.

JMIR Serious Games. 2019 Apr 16;7(2):e11909. doi: 10.2196/11909.


Difluoromethylene at the γ-Lactam α-Position Improves 11-Deoxy-8-aza-PGE1 Series EP4 Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE1 Analog (KMN-159) as a Potent EP4 Agonist.

Barrett SD, Holt MC, Kramer JB, Germain B, Ho CS, Ciske FL, Kornilov A, Colombo JM, Uzieblo A, O'Malley JP, Owen TA, Stein AJ, Morano MI.

J Med Chem. 2019 May 9;62(9):4731-4741. doi: 10.1021/acs.jmedchem.9b00336. Epub 2019 Apr 26.


Improving Timeliness of Oncology Assessment and Cancer Treatment Through Implementation of a Multidisciplinary Lung Cancer Clinic.

Stone CJL, Robinson A, Brown E, Mates M, Falkson CB, Owen T, Ashworth A, Parker CM, Mahmud A, Tomiak A, Thain SK, Gregg R, Reid KR, Chung W, Digby GC.

J Oncol Pract. 2019 Feb;15(2):e169-e177. doi: 10.1200/JOP.18.00214. Epub 2019 Jan 7.


B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation.

Sun W, Meednu N, Rosenberg A, Rangel-Moreno J, Wang V, Glanzman J, Owen T, Zhou X, Zhang H, Boyce BF, Anolik JH, Xing L.

Nat Commun. 2018 Dec 3;9(1):5127. doi: 10.1038/s41467-018-07626-8.


2018 White Paper on Recent Issues in Bioanalysis: 'A global bioanalytical community perspective on last decade of incurred samples reanalysis (ISR)' (Part 1 - small molecule regulated bioanalysis, small molecule biomarkers, peptides & oligonucleotide bioanalysis).

Welink J, Xu Y, Yang E, Wilson A, Henderson N, Luo L, Fraser S, Kavita U, Musuku A, James C, Fraier D, Zhang Y, Goykhman D, Summerfield S, Woolf E, Verhaeghe T, Hughes N, Behling A, Brown K, Bulychev A, Buonarati M, Cherry E, Cho SJ, Cludts I, Dillen L, Dodge R, Edmison A, Garofolo F, Green R, Haidar S, Hottenstein C, Ishii-Watabe A, Jang HG, Ji A, Jones B, Kassim S, Ma M, Lima Santos GM, Norris DA, Owen T, Piccoli S, Ramanathan R, Röhl I, Rosenbaum AI, Saito Y, Sangster T, Savoie N, Stebbins C, Sydor J, de Merbel NV, Verthelyi D, Vinter S, Whale E.

Bioanalysis. 2018 Nov 1;10(22):1781-1801. doi: 10.4155/bio-2018-0268. Epub 2018 Nov 29.


Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits.

Smith JGW, Owen T, Bhagwan JR, Mosqueira D, Scott E, Mannhardt I, Patel A, Barriales-Villa R, Monserrat L, Hansen A, Eschenhagen T, Harding SE, Marston S, Denning C.

Stem Cell Reports. 2018 Nov 13;11(5):1226-1243. doi: 10.1016/j.stemcr.2018.10.006. Epub 2018 Nov 1.


Anxiety in children attending a specialist inherited cardiac arrhythmia clinic: a questionnaire study.

Last AN, English J, Pote H, Shafran R, Owen T, Kaski JP.

BMJ Paediatr Open. 2018 Aug 30;2(1):e000271. doi: 10.1136/bmjpo-2018-000271. eCollection 2018.


Therapeutic interventions in children and adolescents with patellar tendon related pain: a systematic review.

Cairns G, Owen T, Kluzek S, Thurley N, Holden S, Rathleff MS, Dean BJF.

BMJ Open Sport Exerc Med. 2018 Aug 13;4(1):e000383. doi: 10.1136/bmjsem-2018-000383. eCollection 2018.


Krypton isotopes and noble gas abundances in the coma of comet 67P/Churyumov-Gerasimenko.

Rubin M, Altwegg K, Balsiger H, Bar-Nun A, Berthelier JJ, Briois C, Calmonte U, Combi M, De Keyser J, Fiethe B, Fuselier SA, Gasc S, Gombosi TI, Hansen KC, Kopp E, Korth A, Laufer D, Le Roy L, Mall U, Marty B, Mousis O, Owen T, Rème H, Sémon T, Tzou CY, Waite JH, Wurz P.

Sci Adv. 2018 Jul 4;4(7):eaar6297. doi: 10.1126/sciadv.aar6297. eCollection 2018 Jul.


Immunohistochemical Evaluation of Canine Pituitary Adenomas Obtained by Transsphenoidal Hypophysectomy.

Miller MA, Owen TJ, Bruyette DS, Scott-Moncrieff JC, Ramos-Vara JA, Weng HY, Chen AV, Martin LG, DuSold DM.

Vet Pathol. 2018 Nov;55(6):889-895. doi: 10.1177/0300985818784160. Epub 2018 Jun 20.


Transsphenoidal surgery: accuracy of an image-guided neuronavigation system to approach the pituitary fossa (sella turcica).

Owen TJ, Chen AV, Frey S, Martin LG, Kalebaugh T.

Vet Surg. 2018 Jul;47(5):664-671. doi: 10.1111/vsu.12906. Epub 2018 May 23.


Pre- and postsurgical cognitive trajectories and quantitative MRI changes in Rasmussen syndrome.

Rudebeck SR, Shavel-Jessop S, Varadkar S, Owen T, Cross JH, Vargha-Khadem F, Baldeweg T.

Epilepsia. 2018 Jun;59(6):1210-1219. doi: 10.1111/epi.14192. Epub 2018 May 11.


Dosimetry of inhaled elongate mineral particles in the respiratory tract: The impact of shape factor.

Asgharian B, Owen TP, Kuempel ED, Jarabek AM.

Toxicol Appl Pharmacol. 2018 Dec 15;361:27-35. doi: 10.1016/j.taap.2018.05.001. Epub 2018 May 5. Review.


Variation in routine follow-up care after curative treatment for head-and-neck cancer: a population-based study in Ontario.

Brennan KE, Hall SF, Owen TE, Griffiths RJ, Peng Y.

Curr Oncol. 2018 Apr;25(2):e120-e131. doi: 10.3747/co.25.3892. Epub 2018 Apr 30.


Histopathologic Findings in Canine Pituitary Glands.

Miller MA, Bruyette DS, Scott-Moncrieff JC, Owen TJ, Ramos-Vara JA, Weng HY, Vanderpool AL, Chen AV, Martin LG, DuSold DM, Jahan S.

Vet Pathol. 2018 Nov;55(6):871-879. doi: 10.1177/0300985818766211. Epub 2018 Apr 17.


Direct or indirect post crowns to restore compromised teeth: a review of the literature.

Owen TA, Barber M.

Br Dent J. 2018 Mar 23;224(6):413-418. doi: 10.1038/sj.bdj.2018.218. Review.


Increasing the Stability of Recombinant Human Green Cone Pigment.

Owen TS, Salom D, Sun W, Palczewski K.

Biochemistry. 2018 Feb 13;57(6):1022-1030. doi: 10.1021/acs.biochem.7b01118. Epub 2018 Jan 29.


Nail and Locking Plate for Periprosthetic Fractures.

Kanabur P, Sandilands SM, Whitmer KK, Owen TM, Coniglione FM, Shuler TE.

J Orthop Trauma. 2017 Dec;31(12):e425-e431. doi: 10.1097/BOT.0000000000000939.


Transsphenoidal Surgery for Pituitary Tumors and Other Sellar Masses.

Owen TJ, Martin LG, Chen AV.

Vet Clin North Am Small Anim Pract. 2018 Jan;48(1):129-151. doi: 10.1016/j.cvsm.2017.08.006. Epub 2017 Oct 20. Review.


Age- and strain-related aberrant Ca2+ release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy.

Rowlands CT, Owen T, Lawal S, Cao S, Pandey SS, Yang HY, Song W, Wilkinson R, Alvarez-Laviada A, Gehmlich K, Marston SB, MacLeod KT.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1213-H1226. doi: 10.1152/ajpheart.00244.2017. Epub 2017 Sep 8.


Direct analysis of volatile organic compounds in foods by headspace extraction atmospheric pressure chemical ionisation mass spectrometry.

Perez-Hurtado P, Palmer E, Owen T, Aldcroft C, Allen MH, Jones J, Creaser CS, Lindley MR, Turner MA, Reynolds JC.

Rapid Commun Mass Spectrom. 2017 Nov 30;31(22):1947-1956. doi: 10.1002/rcm.7975.


Magnetic resonance imaging versus computed tomography to plan hemilaminectomies in chondrodystrophic dogs with intervertebral disc extrusion.

Noyes JA, Thomovsky SA, Chen AV, Owen TJ, Fransson BA, Carbonneau KJ, Matthew SM.

Vet Surg. 2017 Oct;46(7):1025-1031. doi: 10.1111/vsu.12700. Epub 2017 Aug 23.


Autonomic regulation of systemic inflammation in humans: A multi-center, blinded observational cohort study.

Ackland GL, Minto G, Clark M, Whittle J, Stephens RCM, Owen T, Prabhu P, Del Arroyo AG.

Brain Behav Immun. 2018 Jan;67:47-53. doi: 10.1016/j.bbi.2017.08.010. Epub 2017 Aug 12.


The effect of nail characteristics on surface bacterial counts of surgical personnel before and after scrubbing.

Hardy JM, Owen TJ, Martinez SA, Jones LP, Davis MA.

Vet Surg. 2017 Oct;46(7):952-961. doi: 10.1111/vsu.12685. Epub 2017 Jun 28.


The £ for lb. Challenge. Evaluation of a novel, workplace-based peer-led weight management programme, 2014-2016.

Bennett D, Owen T, Bradley DT.

Public Health. 2017 Sep;150:93-100. doi: 10.1016/j.puhe.2017.05.007. Epub 2017 Jun 26.


Xenon isotopes in 67P/Churyumov-Gerasimenko show that comets contributed to Earth's atmosphere.

Marty B, Altwegg K, Balsiger H, Bar-Nun A, Bekaert DV, Berthelier JJ, Bieler A, Briois C, Calmonte U, Combi M, De Keyser J, Fiethe B, Fuselier SA, Gasc S, Gombosi TI, Hansen KC, Hässig M, Jäckel A, Kopp E, Korth A, Le Roy L, Mall U, Mousis O, Owen T, Rème H, Rubin M, Sémon T, Tzou CY, Waite JH, Wurz P.

Science. 2017 Jun 9;356(6342):1069-1072. doi: 10.1126/science.aal3496.


D2O and HDS in the coma of 67P/Churyumov-Gerasimenko.

Altwegg K, Balsiger H, Berthelier JJ, Bieler A, Calmonte U, De Keyser J, Fiethe B, Fuselier SA, Gasc S, Gombosi TI, Owen T, Le Roy L, Rubin M, Sémon T, Tzou CY.

Philos Trans A Math Phys Eng Sci. 2017 Jul 13;375(2097). pii: 20160253. doi: 10.1098/rsta.2016.0253.


Jupiter's interior and deep atmosphere: The initial pole-to-pole passes with the Juno spacecraft.

Bolton SJ, Adriani A, Adumitroaie V, Allison M, Anderson J, Atreya S, Bloxham J, Brown S, Connerney JEP, DeJong E, Folkner W, Gautier D, Grassi D, Gulkis S, Guillot T, Hansen C, Hubbard WB, Iess L, Ingersoll A, Janssen M, Jorgensen J, Kaspi Y, Levin SM, Li C, Lunine J, Miguel Y, Mura A, Orton G, Owen T, Ravine M, Smith E, Steffes P, Stone E, Stevenson D, Thorne R, Waite J, Durante D, Ebert RW, Greathouse TK, Hue V, Parisi M, Szalay JR, Wilson R.

Science. 2017 May 26;356(6340):821-825. doi: 10.1126/science.aal2108.


Radius and ulna fracture repair with the IMEX miniature circular external skeletal fixation system in 37 small and toy breed dogs: A retrospective study.

Bierens D, Unis MD, Cabrera SY, Kass PH, Owen TJ, Mueller MG.

Vet Surg. 2017 May;46(4):587-595. doi: 10.1111/vsu.12647. Epub 2017 Mar 28.


Theory of mind, emotional and social functioning, and motor severity in children and adolescents with dystonic cerebral palsy.

Adegboye D, Sterr A, Lin JP, Owen TJ.

Eur J Paediatr Neurol. 2017 May;21(3):549-556. doi: 10.1016/j.ejpn.2017.01.013. Epub 2017 Jan 31.


Quality of life and swallowing with standard chemoradiotherapy versus accelerated radiotherapy and panitumumab in locoregionally advanced carcinoma of the head and neck: A phase III randomised trial from the Canadian Cancer Trials Group (HN.6).

Ringash J, Waldron JN, Siu LL, Martino R, Winquist E, Wright JR, Nabid A, Hay JH, Hammond A, Sultanem K, Hotte S, Leong C, El-Gayed AA, Naz F, Ramchandar K, Owen TE, Montenegro A, O'Sullivan B, Chen BE, Parulekar WR.

Eur J Cancer. 2017 Feb;72:192-199. doi: 10.1016/j.ejca.2016.11.008. Epub 2016 Dec 29.


Canadian Phase III Randomized Trial of Stereotactic Body Radiotherapy Versus Conventionally Hypofractionated Radiotherapy for Stage I, Medically Inoperable Non-Small-Cell Lung Cancer - Rationale and Protocol Design for the Ontario Clinical Oncology Group (OCOG)-LUSTRE Trial.

Swaminath A, Wierzbicki M, Parpia S, Wright JR, Tsakiridis TK, Okawara GS, Kundapur V, Bujold A, Ahmed N, Hirmiz K, Kurien E, Filion E, Gabos Z, Faria S, Louie AV, Owen T, Wai E, Ramchandar K, Chan EK, Julian J, Cline K, Whelan TJ.

Clin Lung Cancer. 2017 Mar;18(2):250-254. doi: 10.1016/j.cllc.2016.08.002. Epub 2016 Oct 3.


First quality score for referral letters in gastroenterology-a validation study.

Eskeland SL, Brunborg C, Seip B, Wiencke K, Hovde Ø, Owen T, Skogestad E, Huppertz-Hauss G, Halvorsen FA, Garborg K, Aabakken L, de Lange T.

BMJ Open. 2016 Oct 8;6(10):e012835. doi: 10.1136/bmjopen-2016-012835.


Stable cognitive functioning with improved perceptual reasoning in children with dyskinetic cerebral palsy and other secondary dystonias after deep brain stimulation.

Owen T, Adegboye D, Gimeno H, Selway R, Lin JP.

Eur J Paediatr Neurol. 2017 Jan;21(1):193-201. doi: 10.1016/j.ejpn.2016.10.003. Epub 2016 Oct 21.


What parents think and feel about deep brain stimulation in paediatric secondary dystonia including cerebral palsy: A qualitative study of parental decision-making.

Austin A, Lin JP, Selway R, Ashkan K, Owen T.

Eur J Paediatr Neurol. 2017 Jan;21(1):185-192. doi: 10.1016/j.ejpn.2016.08.011. Epub 2016 Sep 6.


A Single Aspartate Coordinates Two Catalytic Steps in Hedgehog Autoprocessing.

Xie J, Owen T, Xia K, Callahan B, Wang C.

J Am Chem Soc. 2016 Aug 31;138(34):10806-9. doi: 10.1021/jacs.6b06928. Epub 2016 Aug 19.


'I could not have survived without Kelly and her team'.

Owen T.

Nurs Stand. 2016 Aug 3;30(49):65. doi: 10.7748/ns.30.49.65.s52.


Prebiotic chemicals-amino acid and phosphorus-in the coma of comet 67P/Churyumov-Gerasimenko.

Altwegg K, Balsiger H, Bar-Nun A, Berthelier JJ, Bieler A, Bochsler P, Briois C, Calmonte U, Combi MR, Cottin H, De Keyser J, Dhooghe F, Fiethe B, Fuselier SA, Gasc S, Gombosi TI, Hansen KC, Haessig M, Jäckel A, Kopp E, Korth A, Le Roy L, Mall U, Marty B, Mousis O, Owen T, Rème H, Rubin M, Sémon T, Tzou CY, Hunter Waite J, Wurz P.

Sci Adv. 2016 May 27;2(5):e1600285. doi: 10.1126/sciadv.1600285. eCollection 2016 May.


Comparisons of synthesized and individual reinforcement contingencies during functional analysis.

Fisher WW, Greer BD, Romani PW, Zangrillo AN, Owen TM.

J Appl Behav Anal. 2016 Sep;49(3):596-616. doi: 10.1002/jaba.314. Epub 2016 May 13.


Validation of the Pictorial Infant Communication Scale for preschool-aged children with autism spectrum disorder.

Ghilain CS, Parlade MV, McBee MT, Coman DC, Owen T, Gutierrez A, Boyd B, Odom S, Alessandri M.

Autism. 2017 Feb;21(2):203-216. doi: 10.1177/1362361316636757. Epub 2016 Jul 9.


A comparison of endoscopy versus pathology sizing of colorectal adenomas and potential implications for surveillance colonoscopy.

Taylor JL, Coleman HG, Gray RT, Kelly PJ, Cameron RI, O'Neill CJ, Shah RM, Owen TA, Dickey W, Loughrey MB.

Gastrointest Endosc. 2016 Aug;84(2):341-51. doi: 10.1016/j.gie.2016.04.009. Epub 2016 Apr 19.


The development of Attitudes of People from Ethnic Minorities to Help-Seeking for Dementia (APEND): a questionnaire to measure attitudes to help-seeking for dementia in people from South Asian backgrounds in the UK.

Hailstone J, Mukadam N, Owen T, Cooper C, Livingston G.

Int J Geriatr Psychiatry. 2017 Mar;32(3):288-296. doi: 10.1002/gps.4462. Epub 2016 Mar 21.


Inhibition of G Protein βγ Subunit Signaling Abrogates Nephritis in Lupus-Prone Mice.

Rangel-Moreno J, To JY, Owen T, Goldman BI, Smrcka AV, Anolik JH.

Arthritis Rheumatol. 2016 Sep;68(9):2244-56. doi: 10.1002/art.39673.

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