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Items: 23

1.

Interplay between Immune Checkpoint Proteins and Cellular Metabolism.

Lim S, Phillips JB, Madeira da Silva L, Zhou M, Fodstad O, Owen LB, Tan M.

Cancer Res. 2017 Mar 15;77(6):1245-1249. doi: 10.1158/0008-5472.CAN-16-1647. Epub 2017 Feb 28. Review.

2.

De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome.

Kim JH, Shinde DN, Reijnders MRF, Hauser NS, Belmonte RL, Wilson GR, Bosch DGM, Bubulya PA, Shashi V, Petrovski S, Stone JK, Park EY, Veltman JA, Sinnema M, Stumpel CTRM, Draaisma JM, Nicolai J; University of Washington Center for Mendelian Genomics, Yntema HG, Lindstrom K, de Vries BBA, Jewett T, Santoro SL, Vogt J; Deciphering Developmental Disorders Study, Bachman KK, Seeley AH, Krokosky A, Turner C, Rohena L, Hempel M, Kortüm F, Lessel D, Neu A, Strom TM, Wieczorek D, Bramswig N, Laccone FA, Behunova J, Rehder H, Gordon CT, Rio M, Romana S, Tang S, El-Khechen D, Cho MT, McWalter K, Douglas G, Baskin B, Begtrup A, Funari T, Schoch K, Stegmann APA, Stevens SJC, Zhang DE, Traver D, Yao X, MacArthur DG, Brunner HG, Mancini GM, Myers RM, Owen LB, Lim ST, Stachura DL, Vissers LELM, Ahn EYE.

Am J Hum Genet. 2016 Sep 1;99(3):711-719. doi: 10.1016/j.ajhg.2016.06.029. Epub 2016 Aug 18.

3.

Allyl isothiocyanate induces replication-associated DNA damage response in NSCLC cells and sensitizes to ionizing radiation.

Tripathi K, Hussein UK, Anupalli R, Barnett R, Bachaboina L, Scalici J, Rocconi RP, Owen LB, Piazza GA, Palle K.

Oncotarget. 2015 Mar 10;6(7):5237-52.

4.

Gli1 protein regulates the S-phase checkpoint in tumor cells via Bid protein, and its inhibition sensitizes to DNA topoisomerase 1 inhibitors.

Tripathi K, Mani C, Barnett R, Nalluri S, Bachaboina L, Rocconi RP, Athar M, Owen LB, Palle K.

J Biol Chem. 2014 Nov 7;289(45):31513-25. doi: 10.1074/jbc.M114.606483. Epub 2014 Sep 24.

5.

Panepoxydone targets NF-kB and FOXM1 to inhibit proliferation, induce apoptosis and reverse epithelial to mesenchymal transition in breast cancer.

Arora R, Yates C, Gary BD, McClellan S, Tan M, Xi Y, Reed E, Piazza GA, Owen LB, Dean-Colomb W.

PLoS One. 2014 Jun 4;9(6):e98370. doi: 10.1371/journal.pone.0098370. eCollection 2014.

6.

An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4.

Arora S, Bhardwaj A, Singh S, Srivastava SK, McClellan S, Nirodi CS, Piazza GA, Grizzle WE, Owen LB, Singh AP.

J Biol Chem. 2013 Jul 19;288(29):21197-207. doi: 10.1074/jbc.M113.484576. Epub 2013 Jun 5.

7.

Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism.

Ding Y, Liu Z, Desai S, Zhao Y, Liu H, Pannell LK, Yi H, Wright ER, Owen LB, Dean-Colomb W, Fodstad O, Lu J, LeDoux SP, Wilson GL, Tan M.

Nat Commun. 2012;3:1271. doi: 10.1038/ncomms2236.

8.

CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions.

Singh AP, Arora S, Bhardwaj A, Srivastava SK, Kadakia MP, Wang B, Grizzle WE, Owen LB, Singh S.

J Biol Chem. 2012 Nov 9;287(46):39115-24. doi: 10.1074/jbc.M112.409581. Epub 2012 Sep 20.

9.

MiR-181 mediates cell differentiation by interrupting the Lin28 and let-7 feedback circuit.

Li X, Zhang J, Gao L, McClellan S, Finan MA, Butler TW, Owen LB, Piazza GA, Xi Y.

Cell Death Differ. 2012 Mar;19(3):378-86. doi: 10.1038/cdd.2011.127. Epub 2011 Oct 7. Erratum in: Cell Death Differ. 2012 Mar;19(3):551.

10.

Systematic evaluation of three microRNA profiling platforms: microarray, beads array, and quantitative real-time PCR array.

Wang B, Howel P, Bruheim S, Ju J, Owen LB, Fodstad O, Xi Y.

PLoS One. 2011 Feb 11;6(2):e17167. doi: 10.1371/journal.pone.0017167.

11.

CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy.

Singh S, Srivastava SK, Bhardwaj A, Owen LB, Singh AP.

Br J Cancer. 2010 Nov 23;103(11):1671-9. doi: 10.1038/sj.bjc.6605968. Epub 2010 Nov 2.

12.

Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol.

Zhou M, Zhao Y, Ding Y, Liu H, Liu Z, Fodstad O, Riker AI, Kamarajugadda S, Lu J, Owen LB, Ledoux SP, Tan M.

Mol Cancer. 2010 Feb 9;9:33. doi: 10.1186/1476-4598-9-33.

13.

CXCL8 and its cognate receptors in melanoma progression and metastasis.

Singh S, Singh AP, Sharma B, Owen LB, Singh RK.

Future Oncol. 2010 Jan;6(1):111-6. doi: 10.2217/fon.09.128. Review.

14.

S179D prolactin diminishes the effects of UV light on epidermal gamma delta T cells.

Guzmán EA, Langowski JL, De Guzman A, Muller HK, Walker AM, Owen LB.

Mol Cell Endocrinol. 2008 Jan 2;280(1-2):6-12. Epub 2007 Sep 11.

15.

The CD95 receptor: apoptosis revisited.

Peter ME, Budd RC, Desbarats J, Hedrick SM, Hueber AO, Newell MK, Owen LB, Pope RM, Tschopp J, Wajant H, Wallach D, Wiltrout RH, Zörnig M, Lynch DH.

Cell. 2007 May 4;129(3):447-50.

16.

Local cytokine levels associated with delayed-type hypersensitivity responses: modulation by gender, ovariectomy, and estrogen replacement.

Ma LJ, Guzmán EA, DeGuzman A, Muller HK, Walker AM, Owen LB.

J Endocrinol. 2007 May;193(2):291-7.

PMID:
17470520
17.

Abnormal expression of interleukin-23 in mycosis fungoides/Sézary syndrome lesions.

Doherty SD, Ni X, Doherty CB, Jones D, Zhao X, Owen LB, Duvic M.

Arch Dermatol Res. 2006 Dec;298(7):353-6. Epub 2006 Sep 26.

PMID:
17021762
18.

The EphB4 receptor-tyrosine kinase promotes the migration of melanoma cells through Rho-mediated actin cytoskeleton reorganization.

Yang NY, Pasquale EB, Owen LB, Ethell IM.

J Biol Chem. 2006 Oct 27;281(43):32574-86. Epub 2006 Aug 31.

19.

Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene.

Maeda Y, Hwang-Verslues WW, Wei G, Fukazawa T, Durbin ML, Owen LB, Liu X, Sladek FM.

Biochem J. 2006 Dec 1;400(2):303-13.

20.

Unexpected effects of UVB in IL-10 transgenic mice: normalization of contact hypersensitivity response.

Ma LJ, Guzmán EA, DeGuzman A, Walter B, Muller HK, Walker AM, Owen LB.

Arch Dermatol Res. 2006 Mar;297(9):417-20. Epub 2006 Jan 3.

PMID:
16389560
21.

Differential biologic effects of CPD and 6-4PP UV-induced DNA damage on the induction of apoptosis and cell-cycle arrest.

Lo HL, Nakajima S, Ma L, Walter B, Yasui A, Ethell DW, Owen LB.

BMC Cancer. 2005 Oct 19;5:135.

22.

Abrogation of delayed type hypersensitivity response to Candida albicans produced by a molecular mimic of phosphorylated prolactin.

Guzmán EA, Chen YH, Langowski JL, De Guzman A, Lo HL, Walter B, Muller HK, Walker AM, Owen LB.

J Neuroimmunol. 2005 Dec 30;170(1-2):31-40. Epub 2005 Sep 19.

PMID:
16169603
23.

Multiosseous osteosarcoma: report of one case and review of the literature.

Owen LB, Eskey CW, Kashatus WC, Brady LW.

Radiol Clin Biol. 1966;35(1):43-59. No abstract available.

PMID:
5226561

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