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Items: 1 to 50 of 101

1.

Machine learning for cluster analysis of localization microscopy data.

Williamson DJ, Burn GL, Simoncelli S, Griffié J, Peters R, Davis DM, Owen DM.

Nat Commun. 2020 Mar 20;11(1):1493. doi: 10.1038/s41467-020-15293-x.

2.

An agent-based model of molecular aggregation at the cell membrane.

Griffié J, Peters R, Owen DM.

PLoS One. 2020 Feb 7;15(2):e0226825. doi: 10.1371/journal.pone.0226825. eCollection 2020.

3.

Differential nanoscale organisation of LFA-1 modulates T-cell migration.

Shannon MJ, Pineau J, Griffié J, Aaron J, Peel T, Williamson DJ, Zamoyska R, Cope AP, Cornish GH, Owen DM.

J Cell Sci. 2019 Oct 16;133(5). pii: jcs232991. doi: 10.1242/jcs.232991.

PMID:
31471459
4.

On the interaction of hyaluronic acid with synovial fluid lipid membranes.

Smith P, Ziolek RM, Gazzarrini E, Owen DM, Lorenz CD.

Phys Chem Chem Phys. 2019 May 15;21(19):9845-9857. doi: 10.1039/c9cp01532a.

PMID:
31032510
5.

Time-Resolved Laurdan Fluorescence Reveals Insights into Membrane Viscosity and Hydration Levels.

Ma Y, Benda A, Kwiatek J, Owen DM, Gaus K.

Biophys J. 2018 Oct 16;115(8):1498-1508. doi: 10.1016/j.bpj.2018.08.041. Epub 2018 Sep 6.

6.

Galectin-9 binds IgM-BCR to regulate B cell signaling.

Cao A, Alluqmani N, Buhari FHM, Wasim L, Smith LK, Quaile AT, Shannon M, Hakim Z, Furmli H, Owen DM, Savchenko A, Treanor B.

Nat Commun. 2018 Aug 17;9(1):3288. doi: 10.1038/s41467-018-05771-8.

7.

Quantitative fibre analysis of single-molecule localization microscopy data.

Peters R, Griffié J, Burn GL, Williamson DJ, Owen DM.

Sci Rep. 2018 Jul 10;8(1):10418. doi: 10.1038/s41598-018-28691-5.

8.

PRODAN differentially influences its local environment.

Suhaj A, Le Marois A, Williamson DJ, Suhling K, Lorenz CD, Owen DM.

Phys Chem Chem Phys. 2018 Jun 13;20(23):16060-16066. doi: 10.1039/c8cp00543e.

PMID:
29850681
9.

Magnetic conjugated polymer nanoparticles doped with a europium complex for biomedical imaging.

Kemal E, Peters R, Bourke S, Fairclough S, Bergstrom-Mann P, Owen DM, Sandiford L, Dailey LA, Green M.

Photochem Photobiol Sci. 2018 Jun 13;17(6):718-721. doi: 10.1039/c7pp00402h.

PMID:
29780995
10.

Spatio-temporal image correlation spectroscopy and super-resolution microscopy to quantify molecular dynamics in T cells.

Ashdown GW, Owen DM.

Methods. 2018 May 1;140-141:112-118. doi: 10.1016/j.ymeth.2018.01.017. Epub 2018 Feb 2. Review.

PMID:
29410223
11.

Toward an Axial Nanoscale Ruler for Fluorescence Microscopy.

Simoncelli S, Makarova M, Wardley W, Owen DM.

ACS Nano. 2017 Dec 26;11(12):11762-11767. doi: 10.1021/acsnano.7b07133. Epub 2017 Nov 21.

PMID:
29161014
12.

Membrane lipid order of sub-synaptic T cell vesicles correlates with their dynamics and function.

Ashdown GW, Williamson DJ, Soh GHM, Day N, Burn GL, Owen DM.

Traffic. 2018 Jan;19(1):29-35. doi: 10.1111/tra.12532. Epub 2017 Nov 7.

13.

3D Bayesian cluster analysis of super-resolution data reveals LAT recruitment to the T cell synapse.

Griffié J, Shlomovich L, Williamson DJ, Shannon M, Aaron J, Khuon S, L Burn G, Boelen L, Peters R, Cope AP, Cohen EAK, Rubin-Delanchy P, Owen DM.

Sci Rep. 2017 Jun 22;7(1):4077. doi: 10.1038/s41598-017-04450-w.

14.

Live-Cell Super-resolution Reveals F-Actin and Plasma Membrane Dynamics at the T Cell Synapse.

Ashdown GW, Burn GL, Williamson DJ, Pandžić E, Peters R, Holden M, Ewers H, Shao L, Wiseman PW, Owen DM.

Biophys J. 2017 Apr 25;112(8):1703-1713. doi: 10.1016/j.bpj.2017.01.038.

15.

Nanoscale Structural Plasticity of the Active Zone Matrix Modulates Presynaptic Function.

Glebov OO, Jackson RE, Winterflood CM, Owen DM, Barker EA, Doherty P, Ewers H, Burrone J.

Cell Rep. 2017 Mar 14;18(11):2715-2728. doi: 10.1016/j.celrep.2017.02.064.

16.

Turning single-molecule localization microscopy into a quantitative bioanalytical tool.

Nicovich PR, Owen DM, Gaus K.

Nat Protoc. 2017 Mar;12(3):453-460. doi: 10.1038/nprot.2016.166. Epub 2017 Feb 2.

PMID:
28151466
17.

Quantification of fibrous spatial point patterns from single-molecule localization microscopy (SMLM) data.

Peters R, Benthem Muñiz M, Griffié J, Williamson DJ, Ashdown GW, Lorenz CD, Owen DM.

Bioinformatics. 2017 Jun 1;33(11):1703-1711. doi: 10.1093/bioinformatics/btx026.

PMID:
28108449
18.

Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets.

Poulter NS, Pollitt AY, Owen DM, Gardiner EE, Andrews RK, Shimizu H, Ishikawa D, Bihan D, Farndale RW, Moroi M, Watson SP, Jung SM.

J Thromb Haemost. 2017 Mar;15(3):549-564. doi: 10.1111/jth.13613. Epub 2017 Feb 16.

19.

A Bayesian cluster analysis method for single-molecule localization microscopy data.

Griffié J, Shannon M, Bromley CL, Boelen L, Burn GL, Williamson DJ, Heard NA, Cope AP, Owen DM, Rubin-Delanchy P.

Nat Protoc. 2016 Dec;11(12):2499-2514. doi: 10.1038/nprot.2016.149. Epub 2016 Nov 17.

20.

Red-emitting protein-coated conjugated polymer nanoparticles.

Peters R, Sandiford L, Owen DM, Kemal E, Bourke S, Dailey LA, Green M.

Photochem Photobiol Sci. 2016 Nov 2;15(11):1448-1452.

PMID:
27714316
21.

Superresolution imaging of the cytoplasmic phosphatase PTPN22 links integrin-mediated T cell adhesion with autoimmunity.

Burn GL, Cornish GH, Potrzebowska K, Samuelsson M, Griffié J, Minoughan S, Yates M, Ashdown G, Pernodet N, Morrison VL, Sanchez-Blanco C, Purvis H, Clarke F, Brownlie RJ, Vyse TJ, Zamoyska R, Owen DM, Svensson LM, Cope AP.

Sci Signal. 2016 Oct 4;9(448):ra99.

PMID:
27703032
22.

Fast live-cell conventional fluorophore nanoscopy with ImageJ through super-resolution radial fluctuations.

Gustafsson N, Culley S, Ashdown G, Owen DM, Pereira PM, Henriques R.

Nat Commun. 2016 Aug 12;7:12471. doi: 10.1038/ncomms12471.

23.

Hydrophobin-Encapsulated Quantum Dots.

Taniguchi S, Sandiford L, Cooper M, Rosca EV, Ahmad Khanbeigi R, Fairclough SM, Thanou M, Dailey LA, Wohlleben W, von Vacano B, de Rosales RT, Dobson PJ, Owen DM, Green M.

ACS Appl Mater Interfaces. 2016 Feb;8(7):4887-93. doi: 10.1021/acsami.5b11354. Epub 2016 Feb 10.

PMID:
26824334
24.

The aPKC/Par3/Par6 Polarity Complex and Membrane Order Are Functionally Interdependent in Epithelia During Vertebrate Organogenesis.

Abu-Siniyeh A, Owen DM, Benzing C, Rinkwitz S, Becker TS, Majumdar A, Gaus K.

Traffic. 2016 Jan;17(1):66-79. doi: 10.1111/tra.12339. Epub 2015 Nov 23.

25.

Bayesian cluster identification in single-molecule localization microscopy data.

Rubin-Delanchy P, Burn GL, Griffié J, Williamson DJ, Heard NA, Cope AP, Owen DM.

Nat Methods. 2015 Nov;12(11):1072-6. doi: 10.1038/nmeth.3612. Epub 2015 Oct 5.

26.

Enhancing Quantum Dots for Bioimaging using Advanced Surface Chemistry and Advanced Optical Microscopy: Application to Silicon Quantum Dots (SiQDs).

Cheng X, Hinde E, Owen DM, Lowe SB, Reece PJ, Gaus K, Gooding JJ.

Adv Mater. 2015 Oct 28;27(40):6144-50. doi: 10.1002/adma.201503223. Epub 2015 Aug 31.

PMID:
26331712
27.

Platelet actin nodules are podosome-like structures dependent on Wiskott-Aldrich syndrome protein and ARP2/3 complex.

Poulter NS, Pollitt AY, Davies A, Malinova D, Nash GB, Hannon MJ, Pikramenou Z, Rappoport JZ, Hartwig JH, Owen DM, Thrasher AJ, Watson SP, Thomas SG.

Nat Commun. 2015 Jun 1;6:7254. doi: 10.1038/ncomms8254.

28.

The nanoscale organization of signaling domains at the plasma membrane.

Griffié J, Burn G, Owen DM.

Curr Top Membr. 2015;75:125-65. doi: 10.1016/bs.ctm.2015.03.004. Epub 2015 Apr 15. Review.

PMID:
26015282
29.

Protein clustering and spatial organization in T-cells.

Shannon MJ, Burn G, Cope A, Cornish G, Owen DM.

Biochem Soc Trans. 2015 Jun;43(3):315-21. doi: 10.1042/BST20140316. Review.

PMID:
26009169
30.

Topographic prominence as a method for cluster identification in single-molecule localisation data.

Griffié J, Boelen L, Burn G, Cope AP, Owen DM.

J Biophotonics. 2015 Nov;8(11-12):925-34. doi: 10.1002/jbio.201400127. Epub 2015 Feb 6.

PMID:
25663080
31.

Discreet and distinct clustering of five model membrane proteins revealed by single molecule localization microscopy.

Magenau A, Owen DM, Yamamoto Y, Tran J, Kwiatek JM, Parton RG, Gaus K.

Mol Membr Biol. 2015;32(1):11-8. doi: 10.3109/09687688.2014.990997. Epub 2015 Jan 14.

PMID:
25586872
32.

Molecular flow quantified beyond the diffraction limit by spatiotemporal image correlation of structured illumination microscopy data.

Ashdown GW, Cope A, Wiseman PW, Owen DM.

Biophys J. 2014 Nov 4;107(9):L21-3. doi: 10.1016/j.bpj.2014.09.018.

33.

Evidence for annexin A6-dependent plasma membrane remodelling of lipid domains.

Alvarez-Guaita A, Vilà de Muga S, Owen DM, Williamson D, Magenau A, García-Melero A, Reverter M, Hoque M, Cairns R, Cornely R, Tebar F, Grewal T, Gaus K, Ayala-Sanmartín J, Enrich C, Rentero C.

Br J Pharmacol. 2015 Apr;172(7):1677-90. doi: 10.1111/bph.13022. Epub 2015 Jan 20.

34.

Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells.

Pollitt AY, Poulter NS, Gitz E, Navarro-Nuñez L, Wang YJ, Hughes CE, Thomas SG, Nieswandt B, Douglas MR, Owen DM, Jackson DG, Dustin ML, Watson SP.

J Biol Chem. 2014 Dec 26;289(52):35695-710. doi: 10.1074/jbc.M114.584284. Epub 2014 Nov 3.

35.

Imaging membrane order using environmentally sensitive fluorophores.

Ashdown GW, Owen DM.

Methods Mol Biol. 2015;1232:115-22. doi: 10.1007/978-1-4939-1752-5_10.

PMID:
25331132
36.

Method for co-cluster analysis in multichannel single-molecule localisation data.

Rossy J, Cohen E, Gaus K, Owen DM.

Histochem Cell Biol. 2014 Jun;141(6):605-12. doi: 10.1007/s00418-014-1208-z. Epub 2014 Mar 19.

PMID:
24643361
37.

Imaging lipid domains in cell membranes: the advent of super-resolution fluorescence microscopy.

Owen DM, Gaus K.

Front Plant Sci. 2013 Dec 12;4:503. doi: 10.3389/fpls.2013.00503. Review.

38.

Prosecuting child abusers, respecting victims: a contrast of approaches in the UK, Tajikistan and Tanzania.

Owen DM.

Paediatr Int Child Health. 2013 Nov;33(4):253-8. doi: 10.1179/2046905513Y.0000000094. Epub 2013 Sep 13. Review.

PMID:
24069954
39.

Superresolution microscopy reveals nanometer-scale reorganization of inhibitory natural killer cell receptors upon activation of NKG2D.

Pageon SV, Cordoba SP, Owen DM, Rothery SM, Oszmiana A, Davis DM.

Sci Signal. 2013 Jul 23;6(285):ra62. doi: 10.1126/scisignal.2003947.

PMID:
23882121
40.

Quantitative analysis of three-dimensional fluorescence localization microscopy data.

Owen DM, Williamson DJ, Boelen L, Magenau A, Rossy J, Gaus K.

Biophys J. 2013 Jul 16;105(2):L05-7. doi: 10.1016/j.bpj.2013.05.063.

41.

Exposure to life events as a risk factor for psychological problems in adults with intellectual disabilities: a longitudinal design.

Hulbert-Williams L, Hastings R, Owen DM, Burns L, Day J, Mulligan J, Noone SJ.

J Intellect Disabil Res. 2014 Jan;58(1):48-60. doi: 10.1111/jir.12050. Epub 2013 Apr 30.

PMID:
23627774
42.

Characterization of a new series of fluorescent probes for imaging membrane order.

Kwiatek JM, Owen DM, Abu-Siniyeh A, Yan P, Loew LM, Gaus K.

PLoS One. 2013;8(2):e52960. doi: 10.1371/journal.pone.0052960. Epub 2013 Feb 4.

43.

CD317/tetherin is an organiser of membrane microdomains.

Billcliff PG, Rollason R, Prior I, Owen DM, Gaus K, Banting G.

J Cell Sci. 2013 Apr 1;126(Pt 7):1553-64. doi: 10.1242/jcs.112953. Epub 2013 Feb 1.

44.

Protein kinase C controls vesicular transport and secretion of apolipoprotein E from primary human macrophages.

Karunakaran D, Kockx M, Owen DM, Burnett JR, Jessup W, Kritharides L.

J Biol Chem. 2013 Feb 15;288(7):5186-97. doi: 10.1074/jbc.M112.428961. Epub 2013 Jan 3.

45.

Sub-resolution lipid domains exist in the plasma membrane and regulate protein diffusion and distribution.

Owen DM, Williamson DJ, Magenau A, Gaus K.

Nat Commun. 2012;3:1256. doi: 10.1038/ncomms2273.

PMID:
23212385
46.

Conformational states of the kinase Lck regulate clustering in early T cell signaling.

Rossy J, Owen DM, Williamson DJ, Yang Z, Gaus K.

Nat Immunol. 2013 Jan;14(1):82-9. doi: 10.1038/ni.2488. Epub 2012 Dec 2.

PMID:
23202272
47.

Super-resolution imaging by localization microscopy.

Owen DM, Magenau A, Williamson DJ, Gaus K.

Methods Mol Biol. 2013;950:81-93. doi: 10.1007/978-1-62703-137-0_6.

PMID:
23086871
48.

Fluorescence localization microscopy: The transition from concept to biological research tool.

Owen DM, Sauer M, Gaus K.

Commun Integr Biol. 2012 Jul 1;5(4):345-9. doi: 10.4161/cib.20348.

49.

Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells.

Rees MD, Dang L, Thai T, Owen DM, Malle E, Thomas SR.

Free Radic Biol Med. 2012 Dec 15;53(12):2344-56. doi: 10.1016/j.freeradbiomed.2012.10.002. Epub 2012 Oct 9.

50.

The Relationship between fenestrations, sieve plates and rafts in liver sinusoidal endothelial cells.

Svistounov D, Warren A, McNerney GP, Owen DM, Zencak D, Zykova SN, Crane H, Huser T, Quinn RJ, Smedsrød B, Le Couteur DG, Cogger VC.

PLoS One. 2012;7(9):e46134. doi: 10.1371/journal.pone.0046134. Epub 2012 Sep 24.

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