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Items: 1 to 50 of 1178

1.

DLL3: an emerging target in small cell lung cancer.

Owen DH, Giffin MJ, Bailis JM, Smit MD, Carbone DP, He K.

J Hematol Oncol. 2019 Jun 18;12(1):61. doi: 10.1186/s13045-019-0745-2. Review.

2.

Choosing your druggability battle.

Owen D.

Nat Chem Biol. 2019 Jun 10. doi: 10.1038/s41589-019-0305-7. [Epub ahead of print] No abstract available.

PMID:
31182788
3.

Resumption of Immune Checkpoint Inhibitor Therapy After Immune-Mediated Colitis.

Abu-Sbeih H, Ali FS, Naqash AR, Owen DH, Patel S, Otterson GA, Kendra K, Ricciuti B, Chiari R, De Giglio A, Sleiman J, Funchain P, Wills B, Zhang J, Naidoo J, Philpott J, Gao J, Subudhi SK, Wang Y.

J Clin Oncol. 2019 Jun 4:JCO1900320. doi: 10.1200/JCO.19.00320. [Epub ahead of print]

PMID:
31163011
4.

In Reply to Slovak et al.

Jackson WC, Cuneo KC, Lawrence TS, Owen D.

Int J Radiat Oncol Biol Phys. 2019 Jul 1;104(3):696-697. doi: 10.1016/j.ijrobp.2019.03.006. No abstract available.

PMID:
31162061
5.

Prediction of tumor control in 90Y radioembolization by logit models with PET/CT based dose metrics.

Dewaraja YK, Devasia T, Kaza RK, Mikell JK, Owen D, Roberson PL, Schipper M.

J Nucl Med. 2019 May 30. pii: jnumed.119.226472. doi: 10.2967/jnumed.119.226472. [Epub ahead of print]

PMID:
31147404
6.

KRAS G12V Mutation in Acquired Resistance to Combined BRAF and MEK Inhibition in Papillary Thyroid Cancer.

Owen DH, Konda B, Sipos J, Liu T, Webb A, Ringel MD, Timmers CD, Shah MH.

J Natl Compr Canc Netw. 2019 May 1;17(5):409-413. doi: 10.6004/jnccn.2019.7292.

PMID:
31085763
7.

Serum Levels of Hepatocyte Growth Factor and CD40 Ligand Predict Radiation-Induced Liver Injury.

Cuneo KC, Devasia T, Sun Y, Schipper MJ, Karnak D, Davis MA, Owen D, Feng M, El Naqa I, Bazzi L, Ten Haken R, Lawrence TS.

Transl Oncol. 2019 Jul;12(7):889-894. doi: 10.1016/j.tranon.2019.04.003. Epub 2019 May 9.

8.

Phagocytosis in the Brain: Homeostasis and Disease.

Galloway DA, Phillips AEM, Owen DRJ, Moore CS.

Front Immunol. 2019 Apr 16;10:790. doi: 10.3389/fimmu.2019.00790. eCollection 2019. Review.

9.

On the interaction of hyaluronic acid with synovial fluid lipid membranes.

Smith P, Ziolek RM, Gazzarrini E, Owen DM, Lorenz CD.

Phys Chem Chem Phys. 2019 May 15;21(19):9845-9857. doi: 10.1039/c9cp01532a.

PMID:
31032510
10.

Functional Adaptation in Radiation Therapy.

Matuszak MM, Kashani R, Green M, Owen D, Jolly S, Mierzwa M.

Semin Radiat Oncol. 2019 Jul;29(3):236-244. doi: 10.1016/j.semradonc.2019.02.006. Review.

PMID:
31027641
11.

Assessing spatial concordance between theranostic pairs using phantom and patient specific acceptance criteria: Application to 99mTc-MAA SPECT/90Y-microsphere PET.

Mikell JK, Majdalany BS, Owen D, Paradis KC, Dewaraja YK.

Int J Radiat Oncol Biol Phys. 2019 Apr 22. pii: S0360-3016(19)30633-9. doi: 10.1016/j.ijrobp.2019.04.012. [Epub ahead of print]

PMID:
31022511
12.

Long-term Clinical Outcomes and Safety Profile of SBRT for Centrally Located NSCLC.

Arnett ALH, Mou B, Owen D, Park SS, Nelson K, Hallemeier CL, Sio T, Garces YI, Olivier KR, Merrell KW.

Adv Radiat Oncol. 2019 Jan 24;4(2):422-428. doi: 10.1016/j.adro.2019.01.002. eCollection 2019 Apr-Jun.

13.

Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF-06372865).

Owen RM, Blakemore D, Cao L, Flanagan N, Fish R, Gibson KR, Gurrell R, Huh CW, Kammonen J, Mortimer-Cassen E, Nickolls SA, Omoto K, Owen D, Pike A, Pryde DC, Reynolds DS, Roeloffs R, Rose C, Stead C, Takeuchi M, Warmus JS, Watson C.

J Med Chem. 2019 Apr 26. doi: 10.1021/acs.jmedchem.9b00322. [Epub ahead of print]

PMID:
30964988
14.

Maternal corticosterone increases thermal sensitivity of heart rate in lizard embryos.

Owen DAS, Sheriff MJ, Heppner JJ, Gerke H, Ensminger DC, MacLeod KJ, Langkilde T.

Biol Lett. 2019 Jan 31;15(1):20180718. doi: 10.1098/rsbl.2018.0718.

PMID:
30958207
15.

Creating Shared Meaning: Communication Between Nurses and Physicians in Nursing Homes.

Owen DC, Ashcraft AS.

Res Gerontol Nurs. 2019 May 1;12(3):121-132. doi: 10.3928/19404921-20190315-01. Epub 2019 Mar 25.

PMID:
30901480
16.

Cortical cerebral blood flow in ageing: effects of haematocrit, sex, ethnicity and diabetes.

Smith LA, Melbourne A, Owen D, Cardoso MJ, Sudre CH, Tillin T, Sokolska M, Atkinson D, Chaturvedi N, Ourselin S, Hughes AD, Barkhof F, Jäger HR.

Eur Radiol. 2019 Mar 18. doi: 10.1007/s00330-019-06096-w. [Epub ahead of print]

PMID:
30887200
17.

Confirmation of Specific Binding of the 18-kDa Translocator Protein (TSPO) Radioligand [18F]GE-180: a Blocking Study Using XBD173 in Multiple Sclerosis Normal Appearing White and Grey Matter.

Sridharan S, Raffel J, Nandoskar A, Record C, Brooks DJ, Owen D, Sharp D, Muraro PA, Gunn R, Nicholas R.

Mol Imaging Biol. 2019 Feb 22. doi: 10.1007/s11307-019-01323-8. [Epub ahead of print]

PMID:
30796709
18.

Thymic regulatory T cells arise via two distinct developmental programs.

Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, Henzler CM, Alegre ML, Anderson MS, August A, Marson A, Zheng Y, Williams CB, Farrar MA.

Nat Immunol. 2019 Feb;20(2):195-205. doi: 10.1038/s41590-018-0289-6. Epub 2019 Jan 14.

PMID:
30643267
19.

Do toxicity patterns vary between programmed death-1 and programmed death ligand-1 inhibitors?

Owen DH, Otterson GA.

J Thorac Dis. 2018 Nov;10(Suppl 33):S4069-S4072. doi: 10.21037/jtd.2018.09.102. No abstract available.

20.

Effects of pathogenic CNVs on physical traits in participants of the UK Biobank.

Owen D, Bracher-Smith M, Kendall KM, Rees E, Einon M, Escott-Price V, Owen MJ, O'Donovan MC, Kirov G.

BMC Genomics. 2018 Dec 4;19(1):867. doi: 10.1186/s12864-018-5292-7.

21.

Impact of 90Y PET gradient-based tumor segmentation on voxel-level dosimetry in liver radioembolization.

Mikell JK, Kaza RK, Roberson PL, Younge KC, Srinivasa RN, Majdalany BS, Cuneo KC, Owen D, Devasia T, Schipper MJ, Dewaraja YK.

EJNMMI Phys. 2018 Nov 30;5(1):31. doi: 10.1186/s40658-018-0230-y.

22.

Transfusion rates with intravenous tranexamic acid in total hip arthroplasty performed using the direct anterior approach.

Free MD, Owen DH, Pascoe E, Allen P, Yang L, Harvie P.

Hip Int. 2018 Nov 27:1120700018811310. doi: 10.1177/1120700018811310. [Epub ahead of print]

PMID:
30477358
23.

Greater reduction in mid-treatment FDG-PET volume may be associated with worse survival in non-small cell lung cancer.

Kong FS, Li L, Wang W, Campbell J, Waller JL, Piert M, Gross M, Cheng M, Owen D, Stenmark M, Huang KC, Frey KA, Ten Haken RK, Lawrence TS.

Radiother Oncol. 2019 Mar;132:241-249. doi: 10.1016/j.radonc.2018.10.006. Epub 2018 Oct 30.

PMID:
30389239
24.

Medical consequences of pathogenic CNVs in adults: analysis of the UK Biobank.

Crawford K, Bracher-Smith M, Owen D, Kendall KM, Rees E, Pardiñas AF, Einon M, Escott-Price V, Walters JTR, O'Donovan MC, Owen MJ, Kirov G.

J Med Genet. 2019 Mar;56(3):131-138. doi: 10.1136/jmedgenet-2018-105477. Epub 2018 Oct 20.

PMID:
30343275
25.

Dosimetric impact of interfractional organs at risk variation during high-dose rate interstitial brachytherapy for gynecologic malignancies.

Hawkins PG, Tang M, Vineberg KA, Young L, Kovach K, Lee C, Maturen KE, Uppal S, Owen D, Schipper MJ, Prisciandaro JI, Jolly S.

Med Dosim. 2018 Oct 15. pii: S0958-3947(18)30104-3. doi: 10.1016/j.meddos.2018.09.001. [Epub ahead of print]

PMID:
30336971
26.

Radiation-Induced Liver Disease and Modern Radiotherapy.

Koay EJ, Owen D, Das P.

Semin Radiat Oncol. 2018 Oct;28(4):321-331. doi: 10.1016/j.semradonc.2018.06.007. Review.

PMID:
30309642
27.

Clinical Case Panel: Treatment Alternatives for Inoperable Hepatocellular Carcinoma.

Toesca DAS, Barry A, Sapisochin G, Beecroft R, Dawson L, Owen D, Mouli S, Lewandowski R, Salem R, Chang DT.

Semin Radiat Oncol. 2018 Oct;28(4):295-308. doi: 10.1016/j.semradonc.2018.08.001. Review.

PMID:
30309640
28.

Allostery and dynamics in small G proteins.

Mott HR, Owen D.

Biochem Soc Trans. 2018 Oct 19;46(5):1333-1343. doi: 10.1042/BST20170569. Epub 2018 Oct 8. Review.

PMID:
30301845
29.

Time-Resolved Laurdan Fluorescence Reveals Insights into Membrane Viscosity and Hydration Levels.

Ma Y, Benda A, Kwiatek J, Owen DM, Gaus K.

Biophys J. 2018 Oct 16;115(8):1498-1508. doi: 10.1016/j.bpj.2018.08.041. Epub 2018 Sep 6.

30.

Separating fetal and maternal placenta circulations using multiparametric MRI.

Melbourne A, Aughwane R, Sokolska M, Owen D, Kendall G, Flouri D, Bainbridge A, Atkinson D, Deprest J, Vercauteren T, David A, Ourselin S.

Magn Reson Med. 2019 Jan;81(1):350-361. doi: 10.1002/mrm.27406. Epub 2018 Sep 21.

31.

Performance/outcomes data and physician process challenges for practical big data efforts in radiation oncology.

Matuszak MM, Fuller CD, Yock TI, Hess CB, McNutt T, Jolly S, Gabriel P, Mayo CS, Thor M, Caissie A, Rao A, Owen D, Smith W, Palta J, Kapoor R, Hayman J, Waddle M, Rosenstein B, Miller R, Choi S, Moreno A, Herman J, Feng M.

Med Phys. 2018 Oct;45(10):e811-e819. doi: 10.1002/mp.13136. Epub 2018 Sep 19.

PMID:
30229946
32.

Structure of the membrane-assembled retromer coat determined by cryo-electron tomography.

Kovtun O, Leneva N, Bykov YS, Ariotti N, Teasdale RD, Schaffer M, Engel BD, Owen DJ, Briggs JAG, Collins BM.

Nature. 2018 Sep;561(7724):561-564. doi: 10.1038/s41586-018-0526-z. Epub 2018 Sep 17.

33.

Magnetic Resonance Imaging Evaluation of Hepatocellular Carcinoma Treated With Stereotactic Body Radiation Therapy: Long Term Imaging Follow-Up.

Mendiratta-Lala M, Masch W, Shankar PR, Hartman HE, Davenport MS, Schipper MJ, Maurino C, Cuneo KC, Lawrence TS, Owen D.

Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):169-179. doi: 10.1016/j.ijrobp.2018.09.004. Epub 2018 Sep 10.

PMID:
30213751
34.

Incidence, Risk Factors, and Effect on Survival of Immune-related Adverse Events in Patients With Non-Small-cell Lung Cancer.

Owen DH, Wei L, Bertino EM, Edd T, Villalona-Calero MA, He K, Shields PG, Carbone DP, Otterson GA.

Clin Lung Cancer. 2018 Nov;19(6):e893-e900. doi: 10.1016/j.cllc.2018.08.008. Epub 2018 Aug 22.

35.

Targeting BRAF Mutations in High-Grade Neuroendocrine Carcinoma of the Colon.

Burkart J, Owen D, Shah MH, Abdel-Misih SRZ, Roychowdhury S, Wesolowski R, Haraldsdottir S, Reeser JW, Samorodnitsky E, Smith A, Konda B.

J Natl Compr Canc Netw. 2018 Sep;16(9):1035-1040. doi: 10.6004/jnccn.2018.7043.

PMID:
30181415
36.

Influence of methods of joint inspection during tibial plateau leveling osteotomy on the radiographic appearance of the patellar tendon.

Owen DJ, Manley R, Casale SA.

Vet Surg. 2018 Oct;47(7):916-922. doi: 10.1111/vsu.12942. Epub 2018 Sep 4.

PMID:
30180275
37.

CRIB effector disorder: exquisite function from chaos.

Owen D, Mott HR.

Biochem Soc Trans. 2018 Oct 19;46(5):1289-1302. doi: 10.1042/BST20170570. Epub 2018 Aug 28. Review.

PMID:
30154092
38.

Galectin-9 binds IgM-BCR to regulate B cell signaling.

Cao A, Alluqmani N, Buhari FHM, Wasim L, Smith LK, Quaile AT, Shannon M, Hakim Z, Furmli H, Owen DM, Savchenko A, Treanor B.

Nat Commun. 2018 Aug 17;9(1):3288. doi: 10.1038/s41467-018-05771-8.

39.

Modeling Patient-Specific Dose-Function Response for Enhanced Characterization of Personalized Functional Damage.

Owen DR, Boonstra PS, Viglianti BL, Balter JM, Schipper MJ, Jackson WC, El Naqa I, Jolly S, Ten Haken RK, Kong FS, Matuszak MM.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):1265-1275. doi: 10.1016/j.ijrobp.2018.05.049. Epub 2018 Jun 1.

PMID:
30108006
40.

Reducing Dendrimer Generation and PEG Chain Length Increases Drug Release and Promotes Anticancer Activity of PEGylated Polylysine Dendrimers Conjugated with Doxorubicin via a Cathepsin-Cleavable Peptide Linker.

Mehta D, Leong N, McLeod VM, Kelly BD, Pathak R, Owen DJ, Porter CJH, Kaminskas LM.

Mol Pharm. 2018 Oct 1;15(10):4568-4576. doi: 10.1021/acs.molpharmaceut.8b00581. Epub 2018 Sep 13.

PMID:
30107748
41.

SYT1-associated neurodevelopmental disorder: a case series.

Baker K, Gordon SL, Melland H, Bumbak F, Scott DJ, Jiang TJ, Owen D, Turner BJ, Boyd SG, Rossi M, Al-Raqad M, Elpeleg O, Peck D, Mancini GMS, Wilke M, Zollino M, Marangi G, Weigand H, Borggraefe I, Haack T, Stark Z, Sadedin S; Broad Center for Mendelian Genomics, Tan TY, Jiang Y, Gibbs RA, Ellingwood S, Amaral M, Kelley W, Kurian MA, Cousin MA, Raymond FL.

Brain. 2018 Sep 1;141(9):2576-2591. doi: 10.1093/brain/awy209.

42.

Bond swapping from a charge cloud allows flexible coordination of upstream signals through WASP: Multiple regulatory roles for the WASP basic region.

Tetley GJN, Szeto A, Fountain AJ, Mott HR, Owen D.

J Biol Chem. 2018 Sep 28;293(39):15136-15151. doi: 10.1074/jbc.RA118.003290. Epub 2018 Aug 13.

43.

Results of a randomized, double blind, placebo controlled, crossover trial of melatonin for treatment of Nocturia in adults with multiple sclerosis (MeNiMS).

Drake MJ, Canham L, Cotterill N, Delgado D, Homewood J, Inglis K, Johnson L, Kisanga MC, Owen D, White P, Cottrell D.

BMC Neurol. 2018 Aug 6;18(1):107. doi: 10.1186/s12883-018-1114-4.

44.

Maternal stress alters the phenotype of the mother, her eggs and her offspring in a wild-caught lizard.

Ensminger DC, Langkilde T, Owen DAS, MacLeod KJ, Sheriff MJ.

J Anim Ecol. 2018 Nov;87(6):1685-1697. doi: 10.1111/1365-2656.12891. Epub 2018 Aug 30.

PMID:
30074248
45.

Direct Anterior Approach Total Hip Arthroplasty: An Adjunct to an Enhanced Recovery Pathway: Outcomes and Learning Curve Effects in Surgeons Transitioning From Other Surgical Approaches.

Free MD, Owen DH, Agius PA, Pascoe EM, Harvie P.

J Arthroplasty. 2018 Nov;33(11):3490-3495. doi: 10.1016/j.arth.2018.06.033. Epub 2018 Jul 4.

PMID:
30055885
46.

Frequency of Brain Metastases and Multikinase Inhibitor Outcomes in Patients With RET-Rearranged Lung Cancers.

Drilon A, Lin JJ, Filleron T, Ni A, Milia J, Bergagnini I, Hatzoglou V, Velcheti V, Offin M, Li B, Carbone DP, Besse B, Mok T, Awad MM, Wolf J, Owen D, Camidge DR, Riely GJ, Peled N, Kris MG, Mazieres J, Gainor JF, Gautschi O.

J Thorac Oncol. 2018 Oct;13(10):1595-1601. doi: 10.1016/j.jtho.2018.07.004. Epub 2018 Jul 11.

PMID:
30017832
47.

Survival and reproductive costs of repeated acute glucocorticoid elevations in a captive, wild animal.

MacLeod KJ, Sheriff MJ, Ensminger DC, Owen DAS, Langkilde T.

Gen Comp Endocrinol. 2018 Nov 1;268:1-6. doi: 10.1016/j.ygcen.2018.07.006. Epub 2018 Aug 16.

PMID:
30016628
48.

Sex-dependent effects of maternal stress: Stressed moms invest less in sons than daughters.

Owen DAS, Sheriff MJ, Engler HI, Langkilde T.

J Exp Zool A Ecol Integr Physiol. 2018 Jul;329(6-7):317-322. doi: 10.1002/jez.2192. Epub 2018 Jul 10.

PMID:
29992777
49.

Quantitative fibre analysis of single-molecule localization microscopy data.

Peters R, Griffié J, Burn GL, Williamson DJ, Owen DM.

Sci Rep. 2018 Jul 10;8(1):10418. doi: 10.1038/s41598-018-28691-5.

50.

Assessing wandering risk among individuals with Alzheimer's disease and dementia: a pilot study.

Barnard-Brak L, Richman DM, Owen DC.

Psychogeriatrics. 2018 Sep;18(5):388-392. doi: 10.1111/psyg.12336. Epub 2018 Jul 10.

PMID:
29987882

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