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Successful recruitment of a multi-site international randomized placebo-controlled trial in people with HIV with attention to diversity of race and ethnicity: critical role of central coordination.

Fitch KV, Kileel EM, Looby SE, Zanni MV, Sanchez LR, Fichtenbaum CJ, Overton ET, Malvestutto C, Aberg JA, Klingman KL, Alston-Smith B, Lavelle J, Rancourt A, Badal-Faesen S, Cardoso SW, Avihingsanon A, Patil S, Sponseller CA, Melbourne K, Ribaudo HJ, Cooper-Arnold K, Desvigne-Nickens P, Hoffmann U, Douglas PS, Grinspoon SK; REPRIEVE Investigators.

HIV Res Clin Pract. 2020 Feb;21(1):11-23. doi: 10.1080/25787489.2020.1733794. Epub 2020 Mar 11.


Long-Acting Cabotegravir and Rilpivirine after Oral Induction for HIV-1 Infection.

Orkin C, Arasteh K, Górgolas Hernández-Mora M, Pokrovsky V, Overton ET, Girard PM, Oka S, Walmsley S, Bettacchi C, Brinson C, Philibert P, Lombaard J, St Clair M, Crauwels H, Ford SL, Patel P, Chounta V, D'Amico R, Vanveggel S, Dorey D, Cutrell A, Griffith S, Margolis DA, Williams PE, Parys W, Smith KY, Spreen WR.

N Engl J Med. 2020 Mar 19;382(12):1124-1135. doi: 10.1056/NEJMoa1909512. Epub 2020 Mar 4.


Physical activity trends and metabolic health outcomes in people living with HIV in the US, 2008-2015.

Willig AL, Webel AR, Westfall AO, Levitan EB, Crane HM, Buford TW, Burkholder GA, Willig JH, Blashill AJ, Moore RD, Mathews WC, Zinski A, Muhammad J, Geng EH, Napravnik S, Eron JJ, Rodriguez B, Bamman MM, Overton ET.

Prog Cardiovasc Dis. 2020 Feb 11. pii: S0033-0620(20)30035-9. doi: 10.1016/j.pcad.2020.02.005. [Epub ahead of print] Review.


A randomized phase II trial to compare safety and immunogenicity of the MVA-BN smallpox vaccine at various doses in adults with a history of AIDS.

Overton ET, Lawrence SJ, Stapleton JT, Weidenthaler H, Schmidt D, Koenen B, Silbernagl G, Nopora K, Chaplin P.

Vaccine. 2020 Mar 4;38(11):2600-2607. doi: 10.1016/j.vaccine.2020.01.058. Epub 2020 Feb 11.


Sexually transmitted infections and sexual behaviors of men who have sex with men in an American Deep South PrEP clinic.

Gravett RM, Westfall AO, Overton ET, Kudroff K, Muzny CA, Eaton EF.

Int J STD AIDS. 2020 Feb;31(2):127-135. doi: 10.1177/0956462419886228. Epub 2020 Jan 28. No abstract available.


Obesity Affects the Association of Bioelectrical Impedance Phase Angle With Mortality in People Living With HIV.

Cogliandro V, Yester D, Westfall AO, Raper JL, Saag MS, Henostroza G, Overton ET, Willig AL.

J Assoc Nurses AIDS Care. 2020 Jan-Feb;31(1):51-59. doi: 10.1097/JNC.0000000000000077.


Immune activation and inflammation in people with HIV:  Challenging targets.

Utay NS, Overton ET.

J Infect Dis. 2019 Jul 6. pii: jiz351. doi: 10.1093/infdis/jiz351. [Epub ahead of print] No abstract available.


Brief Report: Aging Attenuates the Association Between Coronary Artery Calcification and Bone Loss Among HIV-Infected Persons.

Escota G, Baker J, Bush T, Conley L, Brooks JT, Patel P, Powderly W, Presti R, Overton ET; CDC (Centers for Disease Control and Prevention)-SUN (Study to Understand the Natural History of HIV/AIDS in the Era of Effective Therapy) Investigators.

J Acquir Immune Defic Syndr. 2019 Sep 1;82(1):46-50. doi: 10.1097/QAI.0000000000002092.


Vitamin D does not modulate immune-mediated bone loss during ART initiation.

Yin MT, Chan ES, Brown TT, Kinslow J, Martinson J, Landay A, Melbourne KM, Ribaudo HJ, Overton ET; A5280 Study Team.

Antivir Ther. 2019;24(5):355-362. doi: 10.3851/IMP3316.


Rationale and design of the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE).

Grinspoon SK, Fitch KV, Overton ET, Fichtenbaum CJ, Zanni MV, Aberg JA, Malvestutto C, Lu MT, Currier JS, Sponseller CA, Waclawiw M, Alston-Smith B, Cooper-Arnold K, Klingman KL, Desvigne-Nickens P, Hoffmann U, Ribaudo HJ, Douglas PS; REPRIEVE Investigators.

Am Heart J. 2019 Jun;212:23-35. doi: 10.1016/j.ahj.2018.12.016. Epub 2019 Mar 4.


Rationale and design of the Mechanistic Substudy of the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE): Effects of pitavastatin on coronary artery disease and inflammatory biomarkers.

Hoffmann U, Lu MT, Olalere D, Adami EC, Osborne MT, Ivanov A, Aluru JS, Lee S, Arifovic N, Overton ET, Fichtenbaum CJ, Aberg JA, Alston-Smith B, Klingman KL, Waclawiw M, Burdo TH, Williams KC, Zanni MV, Desvigne-Nickens P, Cooper-Arnold K, Fitch KV, Ribaudo H, Douglas PS, Grinspoon SK; REPRIEVE Investigators.

Am Heart J. 2019 Jun;212:1-12. doi: 10.1016/j.ahj.2019.02.011. Epub 2019 Mar 4.


Rapid Boosting of HIV-1 Neutralizing Antibody Responses in Humans Following a Prolonged Immunologic Rest Period.

Spearman P, Tomaras GD, Montefiori DC, Huang Y, Elizaga ML, Ferrari G, Alam SM, Isaacs A, Ahmed H, Hural J, McElrath MJ, Ouedraogo L, Pensiero M, Butler C, Kalams SA, Overton ET, Barnett SW; HVTN 088 Protocol Team and the NIH/NIAID HIV Vaccine Trials Network.

J Infect Dis. 2019 May 5;219(11):1755-1765. doi: 10.1093/infdis/jiz008.


Associations of food insecurity and psychosocial measures with diet quality in adults aging with HIV.

Muhammad JN, Fernandez JR, Clay OJ, Saag MS, Overton ET, Willig AL.

AIDS Care. 2019 May;31(5):554-562. doi: 10.1080/09540121.2018.1554239. Epub 2018 Dec 17.


HIV-1 latent reservoir size and diversity are stable following brief treatment interruption.

Salantes DB, Zheng Y, Mampe F, Srivastava T, Beg S, Lai J, Li JZ, Tressler RL, Koup RA, Hoxie J, Abdel-Mohsen M, Sherrill-Mix S, McCormick K, Overton ET, Bushman FD, Learn GH, Siliciano RF, Siliciano JM, Tebas P, Bar KJ.

J Clin Invest. 2018 Jul 2;128(7):3102-3115. doi: 10.1172/JCI120194. Epub 2018 Jun 18.


Low-density lipoprotein cholesterol response after statin initiation among persons living with human immunodeficiency virus.

Burkholder GA, Muntner P, Zhao H, Mugavero MJ, Overton ET, Kilgore M, Drozd DR, Crane HM, Moore RD, Mathews WC, Geng E, Boswell S, Floris-Moore M, Rosenson RS.

J Clin Lipidol. 2018 Jul - Aug;12(4):988-998.e5. doi: 10.1016/j.jacl.2018.03.082. Epub 2018 Mar 29.


Alterations in the oral microbiome in HIV-infected participants after antiretroviral therapy administration are influenced by immune status.

Presti RM, Handley SA, Droit L, Ghannoum M, Jacobson M, Shiboski CH, Webster-Cyriaque J, Brown T, Yin MT, Overton ET.

AIDS. 2018 Jun 19;32(10):1279-1287. doi: 10.1097/QAD.0000000000001811.


Immunogenicity and safety of three consecutive production lots of the non replicating smallpox vaccine MVA: A randomised, double blind, placebo controlled phase III trial.

Overton ET, Lawrence SJ, Wagner E, Nopora K, Rösch S, Young P, Schmidt D, Kreusel C, De Carli S, Meyer TP, Weidenthaler H, Samy N, Chaplin P.

PLoS One. 2018 Apr 13;13(4):e0195897. doi: 10.1371/journal.pone.0195897. eCollection 2018.



Elopre L, Kudroff K, Westfall AO, Overton ET, Mugavero MJ.

J Acquir Immune Defic Syndr. 2018 Feb 1;77(2):e22. doi: 10.1097/QAI.0000000000001517. No abstract available.


Vitamin D Supplementation Does Not Affect Metabolic Changes Seen With ART Initiation.

Muhammad J, Chan ES, Brown TT, Tebas P, McComsey GA, Melbourne K, Hardin R, Willig AL, Yin MT, Ribaudo H, Overton ET.

Open Forum Infect Dis. 2017 Dec 11;4(4):ofx210. doi: 10.1093/ofid/ofx210. eCollection 2017 Fall.


Genome-wide admixture and association study of subclinical atherosclerosis in the Women's Interagency HIV Study (WIHS).

Shendre A, Wiener HW, Irvin MR, Aouizerat BE, Overton ET, Lazar J, Liu C, Hodis HN, Limdi NA, Weber KM, Gange SJ, Zhi D, Floris-Moore MA, Ofotokun I, Qi Q, Hanna DB, Kaplan RC, Shrestha S.

PLoS One. 2017 Dec 4;12(12):e0188725. doi: 10.1371/journal.pone.0188725. eCollection 2017.


Direct-Acting Antivirals in Kidney Transplant Patients: Successful Hepatitis C Treatment and Short-Term Reduction in Urinary Protein/Creatinine Ratios.

Goetsch MR, Tamhane A, Varshney M, Kapil A, Overton ET, Towns GC, Franco RA.

Pathog Immun. 2017;2(3):366-375. doi: 10.20411/pai.v2i3.211. Epub 2017 Sep 19.


The Impact of Statin and Angiotensin-Converting Enzyme Inhibitor/Angiotensin Receptor Blocker Therapy on Cognitive Function in Adults With Human Immunodeficiency Virus Infection.

Erlandson KM, Kitch D, Wester CW, Kalayjian RC, Overton ET, Castillo-Mancilla J, Koletar SL, Benson CA, Campbell TB, Robertson K, Lok JJ.

Clin Infect Dis. 2017 Nov 29;65(12):2042-2049. doi: 10.1093/cid/cix645.


Racial differences in calculated bioavailable vitamin D with vitamin D/calcium supplementation.

Yin MT, Chan ES, Brown TT, Tebas P, McComsey GA, Melbourne KM, Napoli A, Hardin WR, Ribaudo HJ, Overton ET; A5280 Study Team.

AIDS. 2017 Nov 13;31(17):2337-2344. doi: 10.1097/QAD.0000000000001621.


Response to Letter from Clement et al. Commenting on "The Right People, Right Places, and Right Practices: Disparities in PrEP Access Among African American Men, Women and MSM in the Deep South".

Elopre L, Kudroff K, Westfall AO, Overton ET, Mugavero MJ.

J Acquir Immune Defic Syndr. 2017 Aug 5. doi: 10.1097/QAI.0000000000001517. [Epub ahead of print] No abstract available.


Examining Sexual Function Among Individuals With HIV in a Midwestern US Urban Outpatient Clinic Setting.

Shacham E, López JD, Souza P, Overton ET.

J Int Assoc Provid AIDS Care. 2017 Sep/Oct;16(5):481-486. doi: 10.1177/2325957417724205. Epub 2017 Aug 9.


Race and sex differences in ambulatory blood pressure measures among HIV+ adults.

Kent ST, Schwartz JE, Shimbo D, Overton ET, Burkholder GA, Oparil S, Mugavero MJ, Muntner P.

J Am Soc Hypertens. 2017 Jul;11(7):420-427.e3. doi: 10.1016/j.jash.2017.05.002. Epub 2017 May 25.


Admixture Mapping of Subclinical Atherosclerosis and Subsequent Clinical Events Among African Americans in 2 Large Cohort Studies.

Shendre A, Wiener H, Irvin MR, Zhi D, Limdi NA, Overton ET, Wassel CL, Divers J, Rotter JI, Post WS, Shrestha S.

Circ Cardiovasc Genet. 2017 Apr;10(2). pii: e001569. doi: 10.1161/CIRCGENETICS.116.001569.


Local Ancestry and Clinical Cardiovascular Events Among African Americans From the Atherosclerosis Risk in Communities Study.

Shendre A, Irvin MR, Wiener H, Zhi D, Limdi NA, Overton ET, Shrestha S.

J Am Heart Assoc. 2017 Apr 10;6(4). pii: e004739. doi: 10.1161/JAHA.116.004739.


Monocyte bioenergetic function is associated with body composition in virologically suppressed HIV-infected women.

Willig AL, Kramer PA, Chacko BK, Darley-Usmar VM, Heath SL, Overton ET.

Redox Biol. 2017 Aug;12:648-656. doi: 10.1016/j.redox.2017.04.005. Epub 2017 Apr 4.


Dysregulation of Systemic and Mucosal Humoral Responses to Microbial and Food Antigens as a Factor Contributing to Microbial Translocation and Chronic Inflammation in HIV-1 Infection.

Hel Z, Xu J, Denning WL, Helton ES, Huijbregts RP, Heath SL, Overton ET, Christmann BS, Elson CO, Goepfert PA, Mestecky J.

PLoS Pathog. 2017 Jan 26;13(1):e1006087. doi: 10.1371/journal.ppat.1006087. eCollection 2017 Jan.


Characterizing Failure to Establish Hepatitis C Care of Baby Boomers Diagnosed in the Emergency Department.

Franco RA, Overton ET, Tamhane AR, Forsythe JM, Rodgers JB, Schexnayder JK, Guthrie D, Thogaripally S, Zinski A, Saag MS, Mugavero MJ, Wang HE, Galbraith JW.

Open Forum Infect Dis. 2016 Oct 4;3(4):ofw211. doi: 10.1093/ofid/ofw211. eCollection 2016 Oct.


Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption.

Bar KJ, Sneller MC, Harrison LJ, Justement JS, Overton ET, Petrone ME, Salantes DB, Seamon CA, Scheinfeld B, Kwan RW, Learn GH, Proschan MA, Kreider EF, Blazkova J, Bardsley M, Refsland EW, Messer M, Clarridge KE, Tustin NB, Madden PJ, Oden K, O'Dell SJ, Jarocki B, Shiakolas AR, Tressler RL, Doria-Rose NA, Bailer RT, Ledgerwood JE, Capparelli EV, Lynch RM, Graham BS, Moir S, Koup RA, Mascola JR, Hoxie JA, Fauci AS, Tebas P, Chun TW.

N Engl J Med. 2016 Nov 24;375(21):2037-2050. Epub 2016 Nov 9.


The hidden risk: Incorporating inflammation and HIV serostatus into coronary artery disease screening.

Payne GA, Overton ET.

J Nucl Cardiol. 2018 Jun;25(3):884-886. doi: 10.1007/s12350-016-0731-9. Epub 2016 Nov 16.


The Relationship of Social Support and Neighborhood Perceptions among Individuals with HIV.

Shacham E, López JD, Önen NF, Overton ET.

J Int Assoc Provid AIDS Care. 2017 Sep/Oct;16(5):440-445. doi: 10.1177/2325957416668033. Epub 2016 Sep 12.


Brief Report: The Right People, Right Places, and Right Practices: Disparities in PrEP Access Among African American Men, Women, and MSM in the Deep South.

Elopre L, Kudroff K, Westfall AO, Overton ET, Mugavero MJ.

J Acquir Immune Defic Syndr. 2017 Jan 1;74(1):56-59.


Metabolic Complications and Glucose Metabolism in HIV Infection: A Review of the Evidence.

Willig AL, Overton ET.

Curr HIV/AIDS Rep. 2016 Oct;13(5):289-96. doi: 10.1007/s11904-016-0330-z. Review.


Duration of Influenza Virus Shedding Among HIV-Infected Adults in the cART Era, 2010-2011.

Patel P, Bush T, Kojic EM, Overton ET, Henry K, Önen N, Rhame F, Conley L, Brooks JT, Fry A.

AIDS Res Hum Retroviruses. 2016 Dec;32(12):1180-1186. Epub 2016 Jun 13.


Effects of once-daily darunavir/ritonavir versus atazanavir/ritonavir on insulin sensitivity in HIV-infected persons over 48 weeks: results of an exploratory substudy of METABOLIK, a phase 4, randomized trial.

Overton ET, Tebas P, Coate B, Ryan R, Perniciaro A, Dayaram YK, De La Rosa G, Baugh BP.

HIV Clin Trials. 2016 Mar;17(2):72-7. doi: 10.1080/15284336.2016.1141468.


Vitamin D and bone loss in HIV.

Hileman CO, Overton ET, McComsey GA.

Curr Opin HIV AIDS. 2016 May;11(3):277-84. doi: 10.1097/COH.0000000000000272. Review.


Ambulatory Blood Pressure Monitoring in Individuals with HIV: A Systematic Review and Meta-Analysis.

Kent ST, Bromfield SG, Burkholder GA, Falzon L, Oparil S, Overton ET, Mugavero MJ, Schwartz JE, Shimbo D, Muntner P.

PLoS One. 2016 Feb 16;11(2):e0148920. doi: 10.1371/journal.pone.0148920. eCollection 2016.


The Silent Epidemic - Frailty and Aging with HIV.

Willig AL, Overton ET, Saag MS.

Total Patient Care HIV HCV. 2016;1(1):6-17.


Normal T-cell activation in elite controllers with preserved CD4+ T-cell counts.

Bansal A, Sterrett S, Erdmann N, Westfall AO, Dionne-Odom J, Overton ET, Goepfert PA.

AIDS. 2015 Nov;29(17):2245-54. doi: 10.1097/QAD.0000000000000860.


Effects of Pegylated Interferon/Ribavirin on Bone Turnover Markers in HIV/Hepatitis C Virus-Coinfected Patients.

Bedimo R, Kang M, Tebas P, Overton ET, Hollabaugh K, McComsey G, Bhattacharya D, Evans C, Brown TT, Taiwo B.

AIDS Res Hum Retroviruses. 2016 Apr;32(4):325-8. doi: 10.1089/AID.2015.0204. Epub 2015 Nov 24.


Mechanisms Influencing Circadian Blood Pressure Patterns Among Individuals with HIV.

Kent ST, Burkholder GA, Tajeu GS, Overton ET, Muntner P.

Curr Hypertens Rep. 2015 Nov;17(11):88. doi: 10.1007/s11906-015-0598-1. Review.


Safety and Immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic Smallpox Vaccine in Vaccinia-Naive and Experienced Human Immunodeficiency Virus-Infected Individuals: An Open-Label, Controlled Clinical Phase II Trial.

Overton ET, Stapleton J, Frank I, Hassler S, Goepfert PA, Barker D, Wagner E, von Krempelhuber A, Virgin G, Meyer TP, Müller J, Bädeker N, Grünert R, Young P, Rösch S, Maclennan J, Arndtz-Wiedemann N, Chaplin P.

Open Forum Infect Dis. 2015 May 5;2(2):ofv040. doi: 10.1093/ofid/ofv040. eCollection 2015 Apr. Erratum in: Open Forum Infect Dis. 2016 Jan;3(1):ofv183.


High Prevalence of Low Bone Mineral Density and Substantial Bone Loss over 4 Years Among HIV-Infected Persons in the Era of Modern Antiretroviral Therapy.

Escota GV, Mondy K, Bush T, Conley L, Brooks JT, Önen N, Patel P, Kojic EM, Henry K, Hammer J, Wood KC, Lichtenstein KA, Overton ET.

AIDS Res Hum Retroviruses. 2016 Jan;32(1):59-67. doi: 10.1089/aid.2015.0158. Epub 2015 Sep 14.


Maternal post-absorptive leucine kinetics during late pregnancy in US women with HIV taking antiretroviral therapy: a cross-sectional pilot study.

Cade WT, Singh GK, Holland MR, Reeds DN, Overton ET, Cibulka N, Bahow K, Presti R, Stephens A, Cahill AG.

Clin Nutr ESPEN. 2015 Aug 1;10(4):e140-e146.


Incidence and Predictors of Abnormal Anal Cytology Findings Among HIV-Infected Adults Receiving Contemporary Antiretroviral Therapy.

Conley LJ, Bush TJ, Darragh TM, Palefsky JM, Unger ER, Patel P, Steinau M, Kojic EM, Martin H, Overton ET, Cu-Uvin S, Hammer J, Henry K, Wood K, Brooks JT; SUN Study Group.

J Infect Dis. 2016 Feb 1;213(3):351-60. doi: 10.1093/infdis/jiv408. Epub 2015 Aug 12.


Daclatasvir plus Sofosbuvir for HCV in Patients Coinfected with HIV-1.

Wyles DL, Ruane PJ, Sulkowski MS, Dieterich D, Luetkemeyer A, Morgan TR, Sherman KE, Dretler R, Fishbein D, Gathe JC Jr, Henn S, Hinestrosa F, Huynh C, McDonald C, Mills A, Overton ET, Ramgopal M, Rashbaum B, Ray G, Scarsella A, Yozviak J, McPhee F, Liu Z, Hughes E, Yin PD, Noviello S, Ackerman P; ALLY-2 Investigators.

N Engl J Med. 2015 Aug 20;373(8):714-25. doi: 10.1056/NEJMoa1503153. Epub 2015 Jul 21.


Low bone mineral density and risk of incident fracture in HIV-infected adults.

Battalora L, Buchacz K, Armon C, Overton ET, Hammer J, Patel P, Chmiel JS, Wood K, Bush TJ, Spear JR, Brooks JT, Young B; HIV Outpatient Study (HOPS) and SUN Study Investigators.

Antivir Ther. 2016;21(1):45-54. doi: 10.3851/IMP2979. Epub 2015 Jul 21.


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