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Items: 1 to 50 of 260

1.

The flinders sensitive line rat model of depression--25 years and still producing.

Overstreet DH, Wegener G.

Pharmacol Rev. 2013 Jan 10;65(1):143-55. doi: 10.1124/pr.111.005397. Print 2013 Jan. Review.

PMID:
23319547
2.

Novel medication targets for the treatment of alcoholism: preclinical studies.

Rezvani AH, Lawrence AJ, Arolfo MP, Levin ED, Overstreet DH.

Recent Pat CNS Drug Discov. 2012 Aug;7(2):151-62. Review.

PMID:
22574676
3.

Modeling depression in animal models.

Overstreet DH.

Methods Mol Biol. 2012;829:125-44. doi: 10.1007/978-1-61779-458-2_7. Review.

PMID:
22231810
4.

Effects of a stressor and corticotrophin releasing factor on ethanol deprivation-induced ethanol intake and anxiety-like behavior in alcohol-preferring P rats.

Knapp DJ, Overstreet DH, Huang M, Wills TA, Whitman BA, Angel RA, Sinnett SE, Breese GR.

Psychopharmacology (Berl). 2011 Nov;218(1):179-89. doi: 10.1007/s00213-011-2366-5. Epub 2011 Jun 4.

PMID:
21643675
5.

Cytokine involvement in stress may depend on corticotrophin releasing factor to sensitize ethanol withdrawal anxiety.

Knapp DJ, Whitman BA, Wills TA, Angel RA, Overstreet DH, Criswell HE, Ming Z, Breese GR.

Brain Behav Immun. 2011 Jun;25 Suppl 1:S146-54. doi: 10.1016/j.bbi.2011.02.018. Epub 2011 Mar 4.

6.

Fear induced neuronal alterations in a genetic model of depression: an fMRI study on awake animals.

Huang W, Heffernan ME, Li Z, Zhang N, Overstreet DH, King JA.

Neurosci Lett. 2011 Feb 4;489(2):74-8. doi: 10.1016/j.neulet.2010.11.069. Epub 2010 Dec 4.

7.

Hepatic drug metabolizing profile of Flinders Sensitive Line rat model of depression.

Kotsovolou O, Ingelman-Sundberg M, Lang MA, Marselos M, Overstreet DH, Papadopoulou-Daifoti Z, Johanson I, Fotopoulos A, Konstandi M.

Prog Neuropsychopharmacol Biol Psychiatry. 2010 Aug 16;34(6):1075-84. doi: 10.1016/j.pnpbp.2010.05.029. Epub 2010 Jun 4.

PMID:
20595028
8.

Interactions of stress and CRF in ethanol-withdrawal induced anxiety in adolescent and adult rats.

Wills TA, Knapp DJ, Overstreet DH, Breese GR.

Alcohol Clin Exp Res. 2010 Sep 1;34(9):1603-12. doi: 10.1111/j.1530-0277.2010.01245.x. Epub 2010 Jun 25.

9.

Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with desipramine in an animal model of depression.

Overstreet DH, Naimoli VM, Griebel G.

Pharmacol Biochem Behav. 2010 Aug;96(2):206-10. doi: 10.1016/j.pbb.2010.05.006. Epub 2010 May 12.

PMID:
20470817
10.

Pro-apoptotic Par-4 and dopamine D2 receptor in temporal cortex in schizophrenia, bipolar disorder and major depression.

Glantz LA, Gilmore JH, Overstreet DH, Salimi K, Lieberman JA, Jarskog LF.

Schizophr Res. 2010 May;118(1-3):292-9. doi: 10.1016/j.schres.2009.12.027. Epub 2010 Jan 13.

11.

Nerve growth factor (NGF) has novel antidepressant-like properties in rats.

Overstreet DH, Fredericks K, Knapp D, Breese G, McMichael J.

Pharmacol Biochem Behav. 2010 Feb;94(4):553-60. doi: 10.1016/j.pbb.2009.11.010. Epub 2009 Nov 27.

12.

Corticotropin-releasing factor (CRF) sensitization of ethanol withdrawal-induced anxiety-like behavior is brain site specific and mediated by CRF-1 receptors: relation to stress-induced sensitization.

Huang MM, Overstreet DH, Knapp DJ, Angel R, Wills TA, Navarro M, Rivier J, Vale W, Breese GR.

J Pharmacol Exp Ther. 2010 Jan;332(1):298-307. doi: 10.1124/jpet.109.159186. Epub 2009 Oct 20.

13.

A selective ALDH-2 inhibitor reduces anxiety in rats.

Overstreet DH, Knapp DJ, Breese GR, Diamond I.

Pharmacol Biochem Behav. 2009 Dec;94(2):255-61. doi: 10.1016/j.pbb.2009.09.004. Epub 2009 Sep 10.

14.

Suppression of heavy drinking and alcohol seeking by a selective ALDH-2 inhibitor.

Arolfo MP, Overstreet DH, Yao L, Fan P, Lawrence AJ, Tao G, Keung WM, Vallee BL, Olive MF, Gass JT, Rubin E, Anni H, Hodge CW, Besheer J, Zablocki J, Leung K, Blackburn BK, Lange LG, Diamond I.

Alcohol Clin Exp Res. 2009 Nov;33(11):1935-44. doi: 10.1111/j.1530-0277.2009.01031.x. Epub 2009 Aug 10.

PMID:
19673742
15.

Increased stress-evoked nitric oxide signalling in the Flinders sensitive line (FSL) rat: a genetic animal model of depression.

Wegener G, Harvey BH, Bonefeld B, Müller HK, Volke V, Overstreet DH, Elfving B.

Int J Neuropsychopharmacol. 2010 May;13(4):461-73. doi: 10.1017/S1461145709990241. Epub 2009 Jul 23.

PMID:
19627650
16.

Evaluation of the relationship between hyperinsulinaemia and myocardial ischaemia/reperfusion injury in a rat model of depression.

Solskov L, Løfgren B, Pold R, Kristiansen SB, Nielsen TT, Overstreet DH, Schmitz O, Bøtker HE, Lund S, Wegener G.

Clin Sci (Lond). 2009 Nov 9;118(4):259-67. doi: 10.1042/CS20090108.

PMID:
19575693
17.

Simultaneous prenatal ethanol and nicotine exposure affect ethanol consumption, ethanol preference and oxytocin receptor binding in adolescent and adult rats.

Williams SK, Cox ET, McMurray MS, Fay EE, Jarrett TM, Walker CH, Overstreet DH, Johns JM.

Neurotoxicol Teratol. 2009 Sep-Oct;31(5):291-302. doi: 10.1016/j.ntt.2009.06.001. Epub 2009 Jun 17.

18.

The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration.

Licht CL, Marcussen AB, Wegener G, Overstreet DH, Aznar S, Knudsen GM.

J Neurochem. 2009 Jun;109(5):1363-74. doi: 10.1111/j.1471-4159.2009.06050.x. Epub 2009 Mar 23.

19.

Carisbamate, a novel antiepileptic candidate compound, attenuates alcohol intake in alcohol-preferring rats.

Rezvani AH, Overstreet DH, Vaidya AH, Zhao B, Levin ED.

Alcohol Clin Exp Res. 2009 Aug;33(8):1366-73. doi: 10.1111/j.1530-0277.2009.00966.x. Epub 2009 Apr 30.

PMID:
19413647
20.

Sensitization, duration, and pharmacological blockade of anxiety-like behavior following repeated ethanol withdrawal in adolescent and adult rats.

Wills TA, Knapp DJ, Overstreet DH, Breese GR.

Alcohol Clin Exp Res. 2009 Mar;33(3):455-63. doi: 10.1111/j.1530-0277.2008.00856.x. Epub 2008 Dec 13.

21.

The novel neuropeptide Y Y5 receptor antagonist Lu AA33810 [N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity.

Walker MW, Wolinsky TD, Jubian V, Chandrasena G, Zhong H, Huang X, Miller S, Hegde LG, Marsteller DA, Marzabadi MR, Papp M, Overstreet DH, Gerald CP, Craig DA.

J Pharmacol Exp Ther. 2009 Mar;328(3):900-11. doi: 10.1124/jpet.108.144634. Epub 2008 Dec 19.

PMID:
19098165
22.

Abstinence from moderate alcohol self-administration alters progenitor cell proliferation and differentiation in multiple brain regions of male and female P rats.

He J, Overstreet DH, Crews FT.

Alcohol Clin Exp Res. 2009 Jan;33(1):129-38. doi: 10.1111/j.1530-0277.2008.00823.x. Epub 2008 Dec 10.

PMID:
19076732
23.

Antidepressant-like effects of nicotine and reduced nicotinic receptor binding in the Fawn-Hooded rat, an animal model of co-morbid depression and alcoholism.

Tizabi Y, Getachew B, Rezvani AH, Hauser SR, Overstreet DH.

Prog Neuropsychopharmacol Biol Psychiatry. 2009 Apr 30;33(3):398-402. doi: 10.1016/j.pnpbp.2008.09.010. Epub 2008 Sep 19.

24.

Gestational ethanol and nicotine exposure: effects on maternal behavior, oxytocin, and offspring ethanol intake in the rat.

McMurray MS, Williams SK, Jarrett TM, Cox ET, Fay EE, Overstreet DH, Walker CH, Johns JM.

Neurotoxicol Teratol. 2008 Nov-Dec;30(6):475-86. doi: 10.1016/j.ntt.2008.07.001. Epub 2008 Jul 11.

25.

Electroacupuncture reduces voluntary alcohol intake in alcohol-preferring rats via an opiate-sensitive mechanism.

Overstreet DH, Cui CL, Ma YY, Guo CY, Han JS, Lukas SE, Lee DY.

Neurochem Res. 2008 Oct;33(10):2166-70. doi: 10.1007/s11064-008-9791-9. Epub 2008 Jul 17.

PMID:
18633703
26.

Differential dietary ethanol intake and blood ethanol levels in adolescent and adult rats: effects on anxiety-like behavior and seizure thresholds.

Wills TA, Knapp DJ, Overstreet DH, Breese GR.

Alcohol Clin Exp Res. 2008 Aug;32(8):1350-60. doi: 10.1111/j.1530-0277.2008.00709.x. Epub 2008 Jun 6.

27.

Withdrawal emotional-regulation in infant rats from genetic animal models of depression.

Braw Y, Malkesman O, Merenlender A, Bercovich A, Dagan M, Overstreet DH, Weller A.

Behav Brain Res. 2008 Nov 3;193(1):94-100. doi: 10.1016/j.bbr.2008.04.026. Epub 2008 May 4.

PMID:
18539346
28.

Confirmation of antidepressant potential of the selective beta3 adrenoceptor agonist amibegron in an animal model of depression.

Overstreet DH, Stemmelin J, Griebel G.

Pharmacol Biochem Behav. 2008 Jun;89(4):623-6. doi: 10.1016/j.pbb.2008.02.020. Epub 2008 Feb 26.

PMID:
18358519
29.

The reward system and maternal behavior in an animal model of depression: a microdialysis study.

Lavi-Avnon Y, Weller A, Finberg JP, Gispan-Herman I, Kinor N, Stern Y, Schroeder M, Gelber V, Bergman SY, Overstreet DH, Yadid G.

Psychopharmacology (Berl). 2008 Feb;196(2):281-91. Epub 2007 Oct 11.

PMID:
17928996
30.

The amygdala regulates the antianxiety sensitization effect of flumazenil during repeated chronic ethanol or repeated stress.

Knapp DJ, Overstreet DH, Angel RA, Navarro M, Breese GR.

Alcohol Clin Exp Res. 2007 Nov;31(11):1872-82. Epub 2007 Sep 26.

31.

Decoding of dopaminergic mesolimbic activity and depressive behavior.

Friedman A, Deri I, Friedman Y, Dremencov E, Goutkin S, Kravchinsky E, Mintz M, Levi D, Overstreet DH, Yadid G.

J Mol Neurosci. 2007;32(1):72-9.

PMID:
17873290
32.
33.

Repeated lipopolysaccharide (LPS) or cytokine treatments sensitize ethanol withdrawal-induced anxiety-like behavior.

Breese GR, Knapp DJ, Overstreet DH, Navarro M, Wills TA, Angel RA.

Neuropsychopharmacology. 2008 Mar;33(4):867-76. Epub 2007 Jun 6. Erratum in: Neuropsychopharmacology. 2008 Jun;33(7):1777.

34.

Further genetic characterization of the fawn-hooded (FH/Wjd) rat, an animal model of comorbid depression and alcoholism.

Rezvani AH, Overstreet DH, Cleves M, Parsian A.

Psychiatr Genet. 2007 Apr;17(2):77-83.

PMID:
17413446
35.
36.

The Open Field Test for two.

Overstreet DH.

J Psychopharmacol. 2007 Mar;21(2):140. No abstract available.

PMID:
17329290
37.

Effects of atypical anxiolytic N-phenyl-2-[1-[3-(2-pyridinylethynyl)benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats.

Rezvani AH, Overstreet DH, Levin ED, Rosenthal DI, Kordik CP, Reitz AB, Vaidya AH.

Alcohol Clin Exp Res. 2007 Jan;31(1):57-63.

PMID:
17207102
38.

Analysis of alcohol-related phenotypes in F2 progeny derived from FH/Wjd and ACI/N rat strains reveals independent measures and sex differences.

Patra B, Overstreet DH, Rezvani AH, Cleves M, Parsian A.

Behav Brain Res. 2007 Feb 12;177(1):37-44. Epub 2006 Dec 11.

PMID:
17161877
39.

Depressive-like behavior and high alcohol drinking co-occur in the FH/WJD rat but appear to be under independent genetic control.

Overstreet DH, Rezvani AH, Djouma E, Parsian A, Lawrence AJ.

Neurosci Biobehav Rev. 2007;31(1):103-14. Epub 2006 Sep 18. Review.

PMID:
16982094
40.

Modulation of high alcohol drinking in the inbred Fawn-Hooded (FH/Wjd) rat strain: implications for treatment.

Overstreet DH, Rezvani AH, Cowen M, Chen F, Lawrence AJ.

Addict Biol. 2006 Sep;11(3-4):356-73. Review.

PMID:
16961764
41.

Reduction in repeated ethanol-withdrawal-induced anxiety-like behavior by site-selective injections of 5-HT1A and 5-HT2C ligands.

Overstreet DH, Knapp DJ, Angel RA, Navarro M, Breese GR.

Psychopharmacology (Berl). 2006 Jul;187(1):1-12. Epub 2006 May 19.

42.

Brain 5-HT synthesis in the Flinders Sensitive Line rat model of depression: an autoradiographic study.

Hasegawa S, Nishi K, Watanabe A, Overstreet DH, Diksic M.

Neurochem Int. 2006 Apr;48(5):358-66. Epub 2006 Jan 19.

PMID:
16427159
43.
44.

Anxiety-like behaviors in pre-pubertal rats of the Flinders Sensitive Line (FSL) and Wistar-Kyoto (WKY) animal models of depression.

Braw Y, Malkesman O, Dagan M, Bercovich A, Lavi-Avnon Y, Schroeder M, Overstreet DH, Weller A.

Behav Brain Res. 2006 Feb 28;167(2):261-9. Epub 2005 Nov 4.

PMID:
16271773
45.

Antidepressant-like effects of the vasopressin V1b receptor antagonist SSR149415 in the Flinders Sensitive Line rat.

Overstreet DH, Griebel G.

Pharmacol Biochem Behav. 2005 Sep;82(1):223-7. Epub 2005 Sep 21.

PMID:
16181667
46.

Two different putative genetic animal models of childhood depression.

Malkesman O, Braw Y, Maayan R, Weizman A, Overstreet DH, Shabat-Simon M, Kesner Y, Touati-Werner D, Yadid G, Weller A.

Biol Psychiatry. 2006 Jan 1;59(1):17-23. Epub 2005 Aug 10.

PMID:
16095569
47.

Reward and anxiety in genetic animal models of childhood depression.

Malkesman O, Braw Y, Zagoory-Sharon O, Golan O, Lavi-Avnon Y, Schroeder M, Overstreet DH, Yadid G, Weller A.

Behav Brain Res. 2005 Oct 14;164(1):1-10.

PMID:
16055204
48.

Anticholinesterase (DFP) toxicity antagonism by chronic donepezil: a potential nerve agent treatment.

Janowsky DS, Davis JM, Overstreet DH.

Pharmacol Biochem Behav. 2005 Aug;81(4):917-22.

PMID:
16054679
49.

Impaired cardiac and sympathetic autonomic control in rats differing in acetylcholine receptor sensitivity.

Padley JR, Overstreet DH, Pilowsky PM, Goodchild AK.

Am J Physiol Heart Circ Physiol. 2005 Nov;289(5):H1985-92. Epub 2005 Jun 10.

50.

The Flinders Sensitive Line rat: a selectively bred putative animal model of depression.

Overstreet DH, Friedman E, Mathé AA, Yadid G.

Neurosci Biobehav Rev. 2005;29(4-5):739-59. Epub 2005 Apr 22. Review.

PMID:
15925699

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