Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 104


Expression and detergent free purification and reconstitution of the plant plasma membrane Na+/H+ antiporter SOS1 overexpressed in Pichia pastoris.

Dutta D, Esmaili M, Overduin M, Fliegel L.

Biochim Biophys Acta Biomembr. 2020 Mar 1;1862(3):183111. doi: 10.1016/j.bbamem.2019.183111. Epub 2019 Oct 31.


Fgd5 is a Rac1-specific Rho GEF that is selectively inhibited by aurintricarboxylic acid.

Park S, Guo Y, Negre J, Preto J, Smithers CC, Azad AK, Overduin M, Murray AG, Eitzen G.

Small GTPases. 2019 Oct 10:1-14. doi: 10.1080/21541248.2019.1674765. [Epub ahead of print]


Structures and Interactions of Transmembrane Targets in Native Nanodiscs.

Overduin M, Esmaili M.

SLAS Discov. 2019 Dec;24(10):943-952. doi: 10.1177/2472555219857691. Epub 2019 Jun 26.


JoVE Methods Collection Highlights: Protein-Protein Interactions.

Barr A, Overduin M.

J Vis Exp. 2019 Jun 10;(148). doi: 10.3791/59816.


Memtein: The fundamental unit of membrane-protein structure and function.

Overduin M, Esmaili M.

Chem Phys Lipids. 2019 Jan;218:73-84. doi: 10.1016/j.chemphyslip.2018.11.008. Epub 2018 Nov 30. Review.


Measuring Interactions of Globular and Filamentous Proteins by Nuclear Magnetic Resonance Spectroscopy (NMR) and Microscale Thermophoresis (MST).

Winkelaar G, Trieber C, Kumar J, Overduin M.

J Vis Exp. 2018 Nov 2;(141). doi: 10.3791/58537.


Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering.

Mrozowich T, McLennan S, Overduin M, Patel TR.

J Vis Exp. 2018 Nov 5;(141). doi: 10.3791/58538.


Structure and function of the Fgd family of divergent FYVE domain proteins 1.

Eitzen G, Smithers CC, Murray AG, Overduin M.

Biochem Cell Biol. 2019 Jun;97(3):257-264. doi: 10.1139/bcb-2018-0185. Epub 2018 Oct 11. Review.


YraP Contributes to Cell Envelope Integrity and Virulence of Salmonella enterica Serovar Typhimurium.

Morris FC, Wells TJ, Bryant JA, Schager AE, Sevastsyanovich YR, Squire DJP, Marshall J, Isom GL, Rooke J, Maderbocus R, Knowles TJ, Overduin M, Rossiter AE, Cunningham AF, Henderson IR.

Infect Immun. 2018 Oct 25;86(11). pii: e00829-17. doi: 10.1128/IAI.00829-17. Print 2018 Nov.


Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis.

Geer MJ, van Geffen JP, Gopalasingam P, Vögtle T, Smith CW, Heising S, Kuijpers MJE, Tullemans BME, Jarvis GE, Eble JA, Jeeves M, Overduin M, Heemskerk JWM, Mazharian A, Senis YA.

Blood. 2018 Sep 27;132(13):1413-1425. doi: 10.1182/blood-2017-10-802975. Epub 2018 Jun 11.


Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting.

Lenoir M, Ustunel C, Rajesh S, Kaur J, Moreau D, Gruenberg J, Overduin M.

Nat Commun. 2018 Mar 8;9(1):993. doi: 10.1038/s41467-018-03370-1.


Membrane biology visualized in nanometer-sized discs formed by styrene maleic acid polymers.

Esmaili M, Overduin M.

Biochim Biophys Acta Biomembr. 2018 Feb;1860(2):257-263. doi: 10.1016/j.bbamem.2017.10.019. Epub 2017 Oct 19. Review.


Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments.

Guix FX, Sannerud R, Berditchevski F, Arranz AM, Horré K, Snellinx A, Thathiah A, Saido T, Saito T, Rajesh S, Overduin M, Kumar-Singh S, Radaelli E, Corthout N, Colombelli J, Tosi S, Munck S, Salas IH, Annaert W, De Strooper B.

Mol Neurodegener. 2017 Mar 10;12(1):25. doi: 10.1186/s13024-017-0165-0.


Small-Molecule Protein-Protein Interaction Inhibitor of Oncogenic Rho Signaling.

Diviani D, Raimondi F, Del Vescovo CD, Dreyer E, Reggi E, Osman H, Ruggieri L, Gonano C, Cavin S, Box CL, Lenoir M, Overduin M, Bellucci L, Seeber M, Fanelli F.

Cell Chem Biol. 2016 Sep 22;23(9):1135-1146. doi: 10.1016/j.chembiol.2016.07.015. Epub 2016 Sep 1.


The CD63-Syntenin-1 Complex Controls Post-Endocytic Trafficking of Oncogenic Human Papillomaviruses.

Gräßel L, Fast LA, Scheffer KD, Boukhallouk F, Spoden GA, Tenzer S, Boller K, Bago R, Rajesh S, Overduin M, Berditchevski F, Florin L.

Sci Rep. 2016 Aug 31;6:32337. doi: 10.1038/srep32337.


NMR of Membrane Proteins: Beyond Crystals.

Rajesh S, Overduin M, Bonev BB.

Adv Exp Med Biol. 2016;922:29-42. doi: 10.1007/978-3-319-35072-1_3.


Secondary structure and (1)H, (13)C and (15)N resonance assignments of Skint-1: a selecting ligand for a murine γδ T cell subset implicated in tumour suppression.

Salim M, Willcox CR, Mohammed F, Hayday AC, Overduin M, Willcox BE, Knowles TJ.

Biomol NMR Assign. 2016 Oct;10(2):357-60. doi: 10.1007/s12104-016-9700-0. Epub 2016 Aug 4.


Structural Mechanisms and Drug Discovery Prospects of Rho GTPases.

Smithers CC, Overduin M.

Cells. 2016 Jun 13;5(2). pii: E26. doi: 10.3390/cells5020026. Review.


A method for detergent-free isolation of membrane proteins in their local lipid environment.

Lee SC, Knowles TJ, Postis VL, Jamshad M, Parslow RA, Lin YP, Goldman A, Sridhar P, Overduin M, Muench SP, Dafforn TR.

Nat Protoc. 2016 Jul;11(7):1149-62. doi: 10.1038/nprot.2016.070. Epub 2016 Jun 2.


Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin.

Fogl C, Mohammed F, Al-Jassar C, Jeeves M, Knowles TJ, Rodriguez-Zamora P, White SA, Odintsova E, Overduin M, Chidgey M.

Nat Commun. 2016 Mar 3;7:10827. doi: 10.1038/ncomms10827.


Characterization of a Putative Receptor Binding Surface on Skint-1, a Critical Determinant of Dendritic Epidermal T Cell Selection.

Salim M, Knowles TJ, Hart R, Mohammed F, Woodward MJ, Willcox CR, Overduin M, Hayday AC, Willcox BE.

J Biol Chem. 2016 Apr 22;291(17):9310-21. doi: 10.1074/jbc.M116.722066. Epub 2016 Feb 25.


Sequence-specific 1H, 13C and 15N backbone resonance assignments of the plakin repeat domain of human envoplakin.

Jeeves M, Fogl C, Al-Jassar C, Chidgey M, Overduin M.

Biomol NMR Assign. 2016 Apr;10(1):167-70. doi: 10.1007/s12104-015-9659-2. Epub 2015 Nov 21.


Membrane and Protein Interactions of the Pleckstrin Homology Domain Superfamily.

Lenoir M, Kufareva I, Abagyan R, Overduin M.

Membranes (Basel). 2015 Oct 23;5(4):646-63. doi: 10.3390/membranes5040646.


Cross-species chimeras reveal BamA POTRA and β-barrel domains must be fine-tuned for efficient OMP insertion.

Browning DF, Bavro VN, Mason JL, Sevastsyanovich YR, Rossiter AE, Jeeves M, Wells TJ, Knowles TJ, Cunningham AF, Donald JW, Palmer T, Overduin M, Henderson IR.

Mol Microbiol. 2015 Aug;97(4):646-59. doi: 10.1111/mmi.13052. Epub 2015 Jun 6.


Secondary structure and (1)H, (13)C, (15)N resonance assignments of the endosomal sorting protein sorting nexin 3.

Overduin M, Rajesh S, Gruenberg J, Lenoir M.

Biomol NMR Assign. 2015 Oct;9(2):355-8. doi: 10.1007/s12104-015-9609-z. Epub 2015 Apr 19.


Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins.

Jamshad M, Grimard V, Idini I, Knowles TJ, Dowle MR, Schofield N, Sridhar P, Lin YP, Finka R, Wheatley M, Thomas OR, Palmer RE, Overduin M, Govaerts C, Ruysschaert JM, Edler KJ, Dafforn TR.

Nano Res. 2015 Mar;8(3):774-789. doi: 10.1007/s12274-014-0560-6. Epub 2014 Oct 23.


G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent.

Jamshad M, Charlton J, Lin YP, Routledge SJ, Bawa Z, Knowles TJ, Overduin M, Dekker N, Dafforn TR, Bill RM, Poyner DR, Wheatley M.

Biosci Rep. 2015 Apr 16;35(2). pii: e00188. doi: 10.1042/BSR20140171.


Structural basis of dynamic membrane recognition by trans-Golgi network specific FAPP proteins.

Lenoir M, Grzybek M, Majkowski M, Rajesh S, Kaur J, Whittaker SB, Coskun Ü, Overduin M.

J Mol Biol. 2015 Feb 27;427(4):966-981. doi: 10.1016/j.jmb.2014.12.023. Epub 2015 Jan 8.


Ambidextrous binding of cell and membrane bilayers by soluble matrix metalloproteinase-12.

Koppisetti RK, Fulcher YG, Jurkevich A, Prior SH, Xu J, Lenoir M, Overduin M, Van Doren SR.

Nat Commun. 2014 Nov 21;5:5552. doi: 10.1038/ncomms6552.


Discovery of novel membrane binding structures and functions.

Kufareva I, Lenoir M, Dancea F, Sridhar P, Raush E, Bissig C, Gruenberg J, Abagyan R, Overduin M.

Biochem Cell Biol. 2014 Dec;92(6):555-63. doi: 10.1139/bcb-2014-0074. Epub 2014 Sep 18.


Targeting protein tyrosine phosphatase SHP2 for therapeutic intervention.

Butterworth S, Overduin M, Barr AJ.

Future Med Chem. 2014;6(12):1423-37. doi: 10.4155/fmc.14.88. Review. Erratum in: Future Med Chem. 2014;6(18):2132.


Structural insights into the activation of the RhoA GTPase by the lymphoid blast crisis (Lbc) oncoprotein.

Lenoir M, Sugawara M, Kaur J, Ball LJ, Overduin M.

J Biol Chem. 2014 Aug 22;289(34):23992-4004. doi: 10.1074/jbc.M114.561787. Epub 2014 Jul 3.


Detergent-free purification of ABC (ATP-binding-cassette) transporters.

Gulati S, Jamshad M, Knowles TJ, Morrison KA, Downing R, Cant N, Collins R, Koenderink JB, Ford RC, Overduin M, Kerr ID, Dafforn TR, Rothnie AJ.

Biochem J. 2014 Jul 15;461(2):269-78. doi: 10.1042/BJ20131477.


Mutational and topological analysis of the Escherichia coli BamA protein.

Browning DF, Matthews SA, Rossiter AE, Sevastsyanovich YR, Jeeves M, Mason JL, Wells TJ, Wardius CA, Knowles TJ, Cunningham AF, Bavro VN, Overduin M, Henderson IR.

PLoS One. 2013 Dec 23;8(12):e84512. doi: 10.1371/journal.pone.0084512. eCollection 2013.


Hinged plakin domains provide specialized degrees of articulation in envoplakin, periplakin and desmoplakin.

Al-Jassar C, Bernadό P, Chidgey M, Overduin M.

PLoS One. 2013 Jul 29;8(7):e69767. doi: 10.1371/journal.pone.0069767. Print 2013.


Mechanistic basis of desmosome-targeted diseases.

Al-Jassar C, Bikker H, Overduin M, Chidgey M.

J Mol Biol. 2013 Nov 1;425(21):4006-22. doi: 10.1016/j.jmb.2013.07.035. Epub 2013 Aug 2. Review.


PtdIns(4)P signalling and recognition systems.

Lenoir M, Overduin M.

Adv Exp Med Biol. 2013;991:59-83. doi: 10.1007/978-94-007-6331-9_5. Review.


Viral infection controlled by a calcium-dependent lipid-binding module in ALIX.

Bissig C, Lenoir M, Velluz MC, Kufareva I, Abagyan R, Overduin M, Gruenberg J.

Dev Cell. 2013 May 28;25(4):364-73. doi: 10.1016/j.devcel.2013.04.003. Epub 2013 May 9.


In support of the BMRB.

Markley JL, Akutsu H, Asakura T, Baldus M, Boelens R, Bonvin A, Kaptein R, Bax A, Bezsonova I, Gryk MR, Hoch JC, Korzhnev DM, Maciejewski MW, Case D, Chazin WJ, Cross TA, Dames S, Kessler H, Lange O, Madl T, Reif B, Sattler M, Eliezer D, Fersht A, Forman-Kay J, Kay LE, Fraser J, Gross J, Kortemme T, Sali A, Fujiwara T, Gardner K, Luo X, Rizo-Rey J, Rosen M, Gil RR, Ho C, Rule G, Gronenborn AM, Ishima R, Klein-Seetharaman J, Tang P, van der Wel P, Xu Y, Grzesiek S, Hiller S, Seelig J, Laue ED, Mott H, Nietlispach D, Barsukov I, Lian LY, Middleton D, Blumenschein T, Moore G, Campbell I, Schnell J, Vakonakis IJ, Watts A, Conte MR, Mason J, Pfuhl M, Sanderson MR, Craven J, Williamson M, Dominguez C, Roberts G, Günther U, Overduin M, Werner J, Williamson P, Blindauer C, Crump M, Driscoll P, Frenkiel T, Golovanov A, Matthews S, Parkinson J, Uhrin D, Williams M, Neuhaus D, Oschkinat H, Ramos A, Shaw DE, Steinbeck C, Vendruscolo M, Vuister GW, Walters KJ, Weinstein H, Wüthrich K, Yokoyama S.

Nat Struct Mol Biol. 2012 Sep;19(9):854-60. doi: 10.1038/nsmb.2371. No abstract available.


Structural basis of ligand interactions of the large extracellular domain of tetraspanin CD81.

Rajesh S, Sridhar P, Tews BA, Fénéant L, Cocquerel L, Ward DG, Berditchevski F, Overduin M.

J Virol. 2012 Sep;86(18):9606-16. doi: 10.1128/JVI.00559-12. Epub 2012 Jun 27.


Size and conformation limits to secretion of disulfide-bonded loops in autotransporter proteins.

Leyton DL, Sevastsyanovich YR, Browning DF, Rossiter AE, Wells TJ, Fitzpatrick RE, Overduin M, Cunningham AF, Henderson IR.

J Biol Chem. 2011 Dec 9;286(49):42283-91. doi: 10.1074/jbc.M111.306118. Epub 2011 Oct 17.


Binding to syntenin-1 protein defines a new mode of ubiquitin-based interactions regulated by phosphorylation.

Rajesh S, Bago R, Odintsova E, Muratov G, Baldwin G, Sridhar P, Rajesh S, Overduin M, Berditchevski F.

J Biol Chem. 2011 Nov 11;286(45):39606-14. doi: 10.1074/jbc.M111.262402. Epub 2011 Sep 26.


The nonlinear structure of the desmoplakin plakin domain and the effects of cardiomyopathy-linked mutations.

Al-Jassar C, Knowles T, Jeeves M, Kami K, Behr E, Bikker H, Overduin M, Chidgey M.

J Mol Biol. 2011 Sep 2;411(5):1049-61. doi: 10.1016/j.jmb.2011.06.047. Epub 2011 Jul 2.


Key amino acid residues of ankyrin-sensitive phosphatidylethanolamine/phosphatidylcholine-lipid binding site of βI-spectrin.

Wolny M, Grzybek M, Bok E, Chorzalska A, Lenoir M, Czogalla A, Adamczyk K, Kolondra A, Diakowski W, Overduin M, Sikorski AF.

PLoS One. 2011;6(6):e21538. doi: 10.1371/journal.pone.0021538. Epub 2011 Jun 28.


The essential β-barrel assembly machinery complex components BamD and BamA are required for autotransporter biogenesis.

Rossiter AE, Leyton DL, Tveen-Jensen K, Browning DF, Sevastsyanovich Y, Knowles TJ, Nichols KB, Cunningham AF, Overduin M, Schembri MA, Henderson IR.

J Bacteriol. 2011 Aug;193(16):4250-3. doi: 10.1128/JB.00192-11. Epub 2011 Jun 10.


Surfactant-free purification of membrane proteins with intact native membrane environment.

Jamshad M, Lin YP, Knowles TJ, Parslow RA, Harris C, Wheatley M, Poyner DR, Bill RM, Thomas OR, Overduin M, Dafforn TR.

Biochem Soc Trans. 2011 Jun;39(3):813-8. doi: 10.1042/BST0390813. Review.


Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain.

He J, Scott JL, Heroux A, Roy S, Lenoir M, Overduin M, Stahelin RV, Kutateladze TG.

J Biol Chem. 2011 May 27;286(21):18650-7. doi: 10.1074/jbc.M111.233015. Epub 2011 Mar 22.


Secondary structure and 1H, 13C, 15N resonance assignments of the Golgi-specific PH domain of FAPP1.

Lenoir M, Whittaker SB, Overduin M.

Biomol NMR Assign. 2011 Oct;5(2):185-7. doi: 10.1007/s12104-011-9296-3. Epub 2011 Feb 8.


Structure and function of BamE within the outer membrane and the β-barrel assembly machine.

Knowles TJ, Browning DF, Jeeves M, Maderbocus R, Rajesh S, Sridhar P, Manoli E, Emery D, Sommer U, Spencer A, Leyton DL, Squire D, Chaudhuri RR, Viant MR, Cunningham AF, Henderson IR, Overduin M.

EMBO Rep. 2011 Feb;12(2):123-8. doi: 10.1038/embor.2010.202. Epub 2011 Jan 7.


The role of hydrophobic interactions in ankyrin-spectrin complex formation.

Kolondra A, Lenoir M, Wolny M, Czogalla A, Overduin M, Sikorski AF, Grzybek M.

Biochim Biophys Acta. 2010 Nov;1798(11):2084-9. doi: 10.1016/j.bbamem.2010.07.024. Epub 2010 Aug 2.

Supplemental Content

Loading ...
Support Center