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Items: 1 to 50 of 177

1.

RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts.

Tongaonkar P, Punj V, Subramanian A, Tran DQ, Trinh KK, Schaal JB, Laragione T, Ouellette AJ, Gulko PS, Selsted ME.

Physiol Genomics. 2019 Dec 1;51(12):657-667. doi: 10.1152/physiolgenomics.00066.2019. Epub 2019 Nov 25.

PMID:
31762409
2.

Rhesus Theta Defensin 1 Promotes Long Term Survival in Systemic Candidiasis by Host Directed Mechanisms.

Basso V, Tran DQ, Schaal JB, Tran P, Eriguchi Y, Ngole D, Cabebe AE, Park AY, Beringer PM, Ouellette AJ, Selsted ME.

Sci Rep. 2019 Nov 15;9(1):16905. doi: 10.1038/s41598-019-53402-z.

3.

Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease.

O'Connell KMS, Ouellette AR, Neuner SM, Dunn AR, Kaczorowski CC.

Genes Brain Behav. 2019 Nov;18(8):e12603. doi: 10.1111/gbb.12603. Epub 2019 Aug 19.

4.

Different and Unequal: A Qualitative Evaluation of Salient Factors Influencing Energy Intake in Adults with Overweight and Obesity.

Dao MC, Messer E, Conigliaro T, Sakaida K, Ouellette AF, Himaras V, Thiron S, Roberts SB.

Nutrients. 2019 Jun 18;11(6). pii: E1365. doi: 10.3390/nu11061365.

5.

Ethics Committees: Team Perspectives and Organizational Responses.

McCarty CA, Barnes R, Thomas M, Sande J, Ouellette A.

J Christ Nurs. 2019 Jul/Sep;36(3):180-184. doi: 10.1097/CNJ.0000000000000582.

PMID:
30585882
6.

Correction for Cobo et al., "Entamoeba histolytica Alters Ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency".

Cobo ER, Holani R, Moreau F, Nakamura K, Ayabe T, Mastroianni JR, Eriguchi Y, Ouellette A, Chadee K.

Infect Immun. 2018 Sep 21;86(10). pii: e00564-18. doi: 10.1128/IAI.00564-18. Print 2018 Oct. No abstract available.

7.

Essential role of IFN-γ in T cell-associated intestinal inflammation.

Eriguchi Y, Nakamura K, Yokoi Y, Sugimoto R, Takahashi S, Hashimoto D, Teshima T, Ayabe T, Selsted ME, Ouellette AJ.

JCI Insight. 2018 Sep 20;3(18). pii: 121886. doi: 10.1172/jci.insight.121886. eCollection 2018 Sep 20.

8.

Establishing a food addiction diagnosis using the Yale Food Addiction Scale: A closer look at the clinically significant distress/functional impairment criterion.

Ouellette AS, Rodrigue C, Lemieux S, Tchernof A, Biertho L, Bégin C.

Appetite. 2018 Oct 1;129:55-61. doi: 10.1016/j.appet.2018.06.031. Epub 2018 Jun 30.

PMID:
29966727
9.

Executive functioning and psychological symptoms in food addiction: a study among individuals with severe obesity.

Rodrigue C, Ouellette AS, Lemieux S, Tchernof A, Biertho L, Bégin C.

Eat Weight Disord. 2018 Aug;23(4):469-478. doi: 10.1007/s40519-018-0530-1. Epub 2018 Jun 26.

PMID:
29947017
10.

Entamoeba histolytica Alters Ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency.

Cobo ER, Holani R, Moreau F, Nakamura K, Ayabe T, Mastroianni JR, Eriguchi Y, Ouellette A, Chadee K.

Infect Immun. 2018 Jun 21;86(7). pii: e00208-18. doi: 10.1128/IAI.00208-18. Print 2018 Jul. Erratum in: Infect Immun. 2018 Sep 21;86(10):.

11.

Fungicidal Potency and Mechanisms of θ-Defensins against Multidrug-Resistant Candida Species.

Basso V, Garcia A, Tran DQ, Schaal JB, Tran P, Ngole D, Aqeel Y, Tongaonkar P, Ouellette AJ, Selsted ME.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00111-18. doi: 10.1128/AAC.00111-18. Print 2018 Jun.

12.

Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α-converting enzyme.

Schaal JB, Maretzky T, Tran DQ, Tran PA, Tongaonkar P, Blobel CP, Ouellette AJ, Selsted ME.

J Biol Chem. 2018 Feb 23;293(8):2725-2734. doi: 10.1074/jbc.RA117.000793. Epub 2018 Jan 9.

13.

Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide.

Schaal JB, Tran DQ, Subramanian A, Patel R, Laragione T, Roberts KD, Trinh K, Tongaonkar P, Tran PA, Minond D, Fields GB, Beringer P, Ouellette AJ, Gulko PS, Selsted ME.

PLoS One. 2017 Nov 16;12(11):e0187868. doi: 10.1371/journal.pone.0187868. eCollection 2017.

14.

An examination of the mechanisms and personality traits underlying food addiction among individuals with severe obesity awaiting bariatric surgery.

Ouellette AS, Rodrigue C, Lemieux S, Tchernof A, Biertho L, Bégin C.

Eat Weight Disord. 2017 Dec;22(4):633-640. doi: 10.1007/s40519-017-0440-7. Epub 2017 Oct 11.

PMID:
29022218
15.

Safety and feasibility of transcranial direct current stimulation (tDCS) combined with sensorimotor retraining in chronic low back pain: a protocol for a pilot randomised controlled trial.

Ouellette AL, Liston MB, Chang WJ, Walton DM, Wand BM, Schabrun SM.

BMJ Open. 2017 Aug 21;7(8):e013080. doi: 10.1136/bmjopen-2016-013080.

16.

BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells.

Frey WD, Chaudhry A, Slepicka PF, Ouellette AM, Kirberger SE, Pomerantz WCK, Hannon GJ, Dos Santos CO.

Stem Cell Reports. 2017 Jul 11;9(1):23-31. doi: 10.1016/j.stemcr.2017.04.031. Epub 2017 Jun 1.

17.

Clinical genetic testing in pediatric cardiomyopathy: Is bigger better?

Ouellette AC, Mathew J, Manickaraj AK, Manase G, Zahavich L, Wilson J, George K, Benson L, Bowdin S, Mital S.

Clin Genet. 2018 Jan;93(1):33-40. doi: 10.1111/cge.13024. Epub 2017 Aug 3.

PMID:
28369760
18.

Medical Schools' Willingness to Accommodate Medical Students with Sensory and Physical Disabilities: Ethical Foundations of a Functional Challenge to "Organic" Technical Standards.

McKee M, Case B, Fausone M, Zazove P, Ouellette A, Fetters MD.

AMA J Ethics. 2016 Oct 1;18(10):993-1002. doi: 10.1001/journalofethics.2016.18.10.medu1-1610.

19.

A Requirement for Metamorphic Interconversion in the Antimicrobial Activity of Chemokine XCL1.

Nevins AM, Subramanian A, Tapia JL, Delgado DP, Tyler RC, Jensen DR, Ouellette AJ, Volkman BF.

Biochemistry. 2016 Jul 12;55(27):3784-93. doi: 10.1021/acs.biochem.6b00353. Epub 2016 Jun 28.

20.

Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration.

Diaz-Ochoa VE, Lam D, Lee CS, Klaus S, Behnsen J, Liu JZ, Chim N, Nuccio SP, Rathi SG, Mastroianni JR, Edwards RA, Jacobo CM, Cerasi M, Battistoni A, Ouellette AJ, Goulding CW, Chazin WJ, Skaar EP, Raffatellu M.

Cell Host Microbe. 2016 Jun 8;19(6):814-25. doi: 10.1016/j.chom.2016.05.005.

21.

Defensins Potentiate a Neutralizing Antibody Response to Enteric Viral Infection.

Gounder AP, Myers ND, Treuting PM, Bromme BA, Wilson SS, Wiens ME, Lu W, Ouellette AJ, Spindler KR, Parks WC, Smith JG.

PLoS Pathog. 2016 Mar 2;12(3):e1005474. doi: 10.1371/journal.ppat.1005474. eCollection 2016 Mar.

22.

U.S. Medical Schools' Compliance With the Americans With Disabilities Act: Findings From a National Study.

Zazove P, Case B, Moreland C, Plegue MA, Hoekstra A, Ouellette A, Sen A, Fetters MD.

Acad Med. 2016 Jul;91(7):979-86. doi: 10.1097/ACM.0000000000001087.

PMID:
26796093
23.

Mutagenic Bypass of an Oxidized Abasic Lesion-Induced DNA Interstrand Cross-Link Analogue by Human Translesion Synthesis DNA Polymerases.

Xu W, Ouellette A, Ghosh S, O'Neill TC, Greenberg MM, Zhao L.

Biochemistry. 2015 Dec 22;54(50):7409-22. doi: 10.1021/acs.biochem.5b01027. Epub 2015 Dec 14.

24.

Rhesus macaque θ-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-κB and MAPK pathways.

Tongaonkar P, Trinh KK, Schaal JB, Tran D, Gulko PS, Ouellette AJ, Selsted ME.

J Leukoc Biol. 2015 Dec;98(6):1061-70. doi: 10.1189/jlb.3A0315-102R. Epub 2015 Aug 12.

25.

Selection against Disability: Abortion, ART, and Access.

Ouellette A.

J Law Med Ethics. 2015 Summer;43(2):211-23. doi: 10.1111/jlme.12235.

PMID:
26242941
26.

n-back task performance and corresponding brain-activation patterns in women with restrictive and bulimic eating-disorder variants: preliminary findings.

Israel M, Klein M, Pruessner J, Thaler L, Spilka M, Efanov S, Ouellette AS, Berlim M, Ali N, Beaudry T, Van den Eynde F, Walker CD, Steiger H.

Psychiatry Res. 2015 Apr 30;232(1):84-91. doi: 10.1016/j.pscychresns.2015.01.022. Epub 2015 Feb 7.

PMID:
25707581
27.

Killing of staphylococci by θ-defensins involves membrane impairment and activation of autolytic enzymes.

Wilmes M, Stockem M, Bierbaum G, Schlag M, Götz F, Tran DQ, Schaal JB, Ouellette AJ, Selsted ME, Sahl HG.

Antibiotics (Basel). 2014;3(4):617-31. doi: 10.3390/antibiotics3040617.

28.

Kinetic and structural mechanisms of (5'S)-8,5'-cyclo-2'-deoxyguanosine-induced dna replication stalling.

Xu W, Ouellette AM, Wawrzak Z, Shriver SJ, Anderson SM, Zhao L.

Biochemistry. 2015 Jan 27;54(3):639-51. doi: 10.1021/bi5014936. Epub 2015 Jan 13.

PMID:
25569151
29.

Differential Susceptibility of Bacteria to Mouse Paneth Cell α-Defensins under Anaerobic Conditions.

Mastroianni JR, Lu W, Selsted ME, Ouellette AJ.

Antibiotics (Basel). 2014;3(4):493-508.

30.

Deloading tape reduces muscle stress at rest and during contraction.

Hug F, Ouellette A, Vicenzino B, Hodges PW, Tucker K.

Med Sci Sports Exerc. 2014 Dec;46(12):2317-25. doi: 10.1249/MSS.0000000000000363.

PMID:
24781888
31.

Hydrophobic determinants of α-defensin bactericidal activity.

Tai KP, Le VV, Selsted ME, Ouellette AJ.

Infect Immun. 2014 Jun;82(6):2195-202. doi: 10.1128/IAI.01414-13. Epub 2014 Mar 10.

32.

Microbicidal effects of α- and θ-defensins against antibiotic-resistant Staphylococcus aureus and Pseudomonas aeruginosa.

Tai KP, Kamdar K, Yamaki J, Le VV, Tran D, Tran P, Selsted ME, Ouellette AJ, Wong-Beringer A.

Innate Immun. 2015 Jan;21(1):17-29. doi: 10.1177/1753425913514784. Epub 2013 Dec 17.

33.

Rattusin, an intestinal α-defensin-related peptide in rats with a unique cysteine spacing pattern and salt-insensitive antibacterial activities.

Patil AA, Ouellette AJ, Lu W, Zhang G.

Antimicrob Agents Chemother. 2013 Apr;57(4):1823-31. doi: 10.1128/AAC.02237-12. Epub 2013 Feb 4.

34.

Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis.

Schaal JB, Tran D, Tran P, Ösapay G, Trinh K, Roberts KD, Brasky KM, Tongaonkar P, Ouellette AJ, Selsted ME.

PLoS One. 2012;7(12):e51337. doi: 10.1371/journal.pone.0051337. Epub 2012 Dec 6.

35.

A novel role for lipid droplets in the organismal antibacterial response.

Anand P, Cermelli S, Li Z, Kassan A, Bosch M, Sigua R, Huang L, Ouellette AJ, Pol A, Welte MA, Gross SP.

Elife. 2012 Nov 13;1:e00003. doi: 10.7554/eLife.00003.

36.

Paneth cell-mediated multiorgan dysfunction after acute kidney injury.

Park SW, Kim M, Kim JY, Ham A, Brown KM, Mori-Akiyama Y, Ouellette AJ, D'Agati VD, Lee HT.

J Immunol. 2012 Dec 1;189(11):5421-33. doi: 10.4049/jimmunol.1200581. Epub 2012 Oct 29.

37.

Immunology. HD6 defensin nanonets.

Ouellette AJ, Selsted ME.

Science. 2012 Jul 27;337(6093):420-1. doi: 10.1126/science.1225906. No abstract available.

PMID:
22837514
38.

CXCL17 is a mucosal chemokine elevated in idiopathic pulmonary fibrosis that exhibits broad antimicrobial activity.

Burkhardt AM, Tai KP, Flores-Guiterrez JP, Vilches-Cisneros N, Kamdar K, Barbosa-Quintana O, Valle-Rios R, Hevezi PA, Zuñiga J, Selman M, Ouellette AJ, Zlotnik A.

J Immunol. 2012 Jun 15;188(12):6399-406. doi: 10.4049/jimmunol.1102903. Epub 2012 May 18.

39.

Cortisol responses on the dexamethasone suppression test among women with Bulimia-spectrum eating disorders: associations with clinical symptoms.

Bruce KR, Steiger H, Israël M, Groleau P, Ng Ying Kin NM, Ouellette AS, Sycz L, Badawi G.

Prog Neuropsychopharmacol Biol Psychiatry. 2012 Aug 7;38(2):241-6. doi: 10.1016/j.pnpbp.2012.04.006. Epub 2012 May 1.

PMID:
22575215
40.

Arginine in α-defensins: differential effects on bactericidal activity correspond to geometry of membrane curvature generation and peptide-lipid phase behavior.

Schmidt NW, Tai KP, Kamdar K, Mishra A, Lai GH, Zhao K, Ouellette AJ, Wong GC.

J Biol Chem. 2012 Jun 22;287(26):21866-72. doi: 10.1074/jbc.M112.358721. Epub 2012 May 7.

41.

High fidelity processing and activation of the human α-defensin HNP1 precursor by neutrophil elastase and proteinase 3.

Tongaonkar P, Golji AE, Tran P, Ouellette AJ, Selsted ME.

PLoS One. 2012;7(3):e32469. doi: 10.1371/journal.pone.0032469. Epub 2012 Mar 20.

42.

Alternative luminal activation mechanisms for paneth cell α-defensins.

Mastroianni JR, Costales JK, Zaksheske J, Selsted ME, Salzman NH, Ouellette AJ.

J Biol Chem. 2012 Mar 30;287(14):11205-12. doi: 10.1074/jbc.M111.333559. Epub 2012 Feb 13.

43.

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance.

Andersson HS, Figueredo SM, Haugaard-Kedström LM, Bengtsson E, Daly NL, Qu X, Craik DJ, Ouellette AJ, Rosengren KJ.

Amino Acids. 2012 Oct;43(4):1471-83.

44.
45.

Biosynthesis and antimicrobial evaluation of backbone-cyclized α-defensins.

Garcia AE, Tai KP, Puttamadappa SS, Shekhtman A, Ouellette AJ, Camarero JA.

Biochemistry. 2011 Dec 6;50(48):10508-19. doi: 10.1021/bi201430f. Epub 2011 Nov 9.

46.

pH Dependence of catalysis by Pseudomonas aeruginosa isochorismate-pyruvate lyase: implications for transition state stabilization and the role of lysine 42.

Olucha J, Ouellette AN, Luo Q, Lamb AL.

Biochemistry. 2011 Aug 23;50(33):7198-207. doi: 10.1021/bi200599j. Epub 2011 Jul 22.

47.

Childhood emotional abuse and eating symptoms in bulimic disorders: an examination of possible mediating variables.

Groleau P, Steiger H, Bruce K, Israel M, Sycz L, Ouellette AS, Badawi G.

Int J Eat Disord. 2012 Apr;45(3):326-32. doi: 10.1002/eat.20939. Epub 2011 Jun 7.

PMID:
21656539
48.

Paneth cell α-defensins in enteric innate immunity.

Ouellette AJ.

Cell Mol Life Sci. 2011 Jul;68(13):2215-29. doi: 10.1007/s00018-011-0714-6. Epub 2011 May 11. Review.

49.

Criterion for amino acid composition of defensins and antimicrobial peptides based on geometry of membrane destabilization.

Schmidt NW, Mishra A, Lai GH, Davis M, Sanders LK, Tran D, Garcia A, Tai KP, McCray PB, Ouellette AJ, Selsted ME, Wong GC.

J Am Chem Soc. 2011 May 4;133(17):6720-7. doi: 10.1021/ja200079a. Epub 2011 Apr 7.

50.

Small-angle X-ray scattering studies of peptide-lipid interactions using the mouse paneth cell α-defensin cryptdin-4.

Mishra A, Tai KP, Schmidt NW, Ouellette AJ, Wong GC.

Methods Enzymol. 2011;492:127-49. doi: 10.1016/B978-0-12-381268-1.00016-1.

PMID:
21333790

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