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Items: 16


Signatures of Breast Cancer Metastasis: aMENAble to Interpretation?

Oudin MJ, Gertler FB.

Trends Cancer. 2017 Jan;3(1):7-9. doi: 10.1016/j.trecan.2016.11.004. Epub 2016 Dec 7.


Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and Metastasis.

Oudin MJ, Weaver VM.

Cold Spring Harb Symp Quant Biol. 2016;81:189-205. doi: 10.1101/sqb.2016.81.030817. Epub 2017 Apr 19. Review.


MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer.

Oudin MJ, Barbier L, Schäfer C, Kosciuk T, Miller MA, Han S, Jonas O, Lauffenburger DA, Gertler FB.

Mol Cancer Ther. 2017 Jan;16(1):143-155. doi: 10.1158/1535-7163.MCT-16-0413. Epub 2016 Nov 3.


MenaINV mediates synergistic cross-talk between signaling pathways driving chemotaxis and haptotaxis.

Oudin MJ, Miller MA, Klazen JA, Kosciuk T, Lussiez A, Hughes SK, Tadros J, Bear JE, Lauffenburger DA, Gertler FB.

Mol Biol Cell. 2016 Oct 15;27(20):3085-3094. Epub 2016 Aug 24.


Parallel In Vivo Assessment of Drug Phenotypes at Various Time Points during Systemic BRAF Inhibition Reveals Tumor Adaptation and Altered Treatment Vulnerabilities.

Jonas O, Oudin MJ, Kosciuk T, Whitman M, Gertler FB, Cima MJ, Flaherty KT, Langer R.

Clin Cancer Res. 2016 Dec 15;22(24):6031-6038. Epub 2016 Apr 18.


Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance.

Miller MA, Oudin MJ, Sullivan RJ, Wang SJ, Meyer AS, Im H, Frederick DT, Tadros J, Griffith LG, Lee H, Weissleder R, Flaherty KT, Gertler FB, Lauffenburger DA.

Cancer Discov. 2016 Apr;6(4):382-99. doi: 10.1158/2159-8290.CD-15-0933. Epub 2016 Mar 16.


Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression.

Oudin MJ, Jonas O, Kosciuk T, Broye LC, Guido BC, Wyckoff J, Riquelme D, Lamar JM, Asokan SB, Whittaker C, Ma D, Langer R, Cima MJ, Wisinski KB, Hynes RO, Lauffenburger DA, Keely PJ, Bear JE, Gertler FB.

Cancer Discov. 2016 May;6(5):516-31. doi: 10.1158/2159-8290.CD-15-1183. Epub 2016 Jan 25.


Characterization of the expression of the pro-metastatic Mena(INV) isoform during breast tumor progression.

Oudin MJ, Hughes SK, Rohani N, Moufarrej MN, Jones JG, Condeelis JS, Lauffenburger DA, Gertler FB.

Clin Exp Metastasis. 2016 Mar;33(3):249-61. doi: 10.1007/s10585-015-9775-5. Epub 2015 Dec 17.


Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis.

Li CM, Gocheva V, Oudin MJ, Bhutkar A, Wang SY, Date SR, Ng SR, Whittaker CA, Bronson RT, Snyder EL, Gertler FB, Jacks T.

Genes Dev. 2015 Sep 1;29(17):1850-62. doi: 10.1101/gad.267393.115.


PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena.

Hughes SK, Oudin MJ, Tadros J, Neil J, Del Rosario A, Joughin BA, Ritsma L, Wyckoff J, Vasile E, Eddy R, Philippar U, Lussiez A, Condeelis JS, van Rheenen J, White F, Lauffenburger DA, Gertler FB.

Mol Biol Cell. 2015 Nov 1;26(21):3867-78. doi: 10.1091/mbc.E15-06-0442. Epub 2015 Sep 2.


Regional effects of endocannabinoid, BDNF and FGF receptor signalling on neuroblast motility and guidance along the rostral migratory stream.

Zhou Y, Oudin MJ, Gajendra S, Sonego M, Falenta K, Williams G, Lalli G, Doherty P.

Mol Cell Neurosci. 2015 Jan;64:32-43. doi: 10.1016/j.mcn.2014.12.001. Epub 2014 Dec 3.


In vivo postnatal electroporation and time-lapse imaging of neuroblast migration in mouse acute brain slices.

Sonego M, Zhou Y, Oudin MJ, Doherty P, Lalli G.

J Vis Exp. 2013 Nov 25;(81). doi: 10.3791/50905.


RalA promotes a direct exocyst-Par6 interaction to regulate polarity in neuronal development.

Das A, Gajendra S, Falenta K, Oudin MJ, Peschard P, Feng S, Wu B, Marshall CJ, Doherty P, Guo W, Lalli G.

J Cell Sci. 2014 Feb 1;127(Pt 3):686-99. doi: 10.1242/jcs.145037. Epub 2013 Nov 27.


DAGL-dependent endocannabinoid signalling: roles in axonal pathfinding, synaptic plasticity and adult neurogenesis.

Oudin MJ, Hobbs C, Doherty P.

Eur J Neurosci. 2011 Nov;34(10):1634-46. doi: 10.1111/j.1460-9568.2011.07831.x. Review.


Endocannabinoids regulate the migration of subventricular zone-derived neuroblasts in the postnatal brain.

Oudin MJ, Gajendra S, Williams G, Hobbs C, Lalli G, Doherty P.

J Neurosci. 2011 Mar 16;31(11):4000-11. doi: 10.1523/JNEUROSCI.5483-10.2011.


A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner.

Goncalves MB, Suetterlin P, Yip P, Molina-Holgado F, Walker DJ, Oudin MJ, Zentar MP, Pollard S, Yáñez-Muñoz RJ, Williams G, Walsh FS, Pangalos MN, Doherty P.

Mol Cell Neurosci. 2008 Aug;38(4):526-36. doi: 10.1016/j.mcn.2008.05.001. Epub 2008 May 15.


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