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Items: 1 to 50 of 213

1.

Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of its Interaction with Actin.

Sakaguchi T, Takefuji M, Wettschureck N, Hamaguchi T, Amano M, Kato K, Tsuda T, Eguchi S, Ishihama S, Mori Y, Yura Y, Yoshida T, Unno K, Okumura T, Ishii H, Shimizu Y, Bando YK, Ohashi K, Ouchi N, Enomoto A, Offermanns S, Kaibuchi K, Murohara T.

Circulation. 2019 Sep 30. doi: 10.1161/CIRCULATIONAHA.119.041019. [Epub ahead of print]

PMID:
31564129
2.

Roles of the Mesenchymal Stromal/Stem Cell Marker Meflin in Cardiac Tissue Repair and the Development of Diastolic Dysfunction.

Hara A, Kobayashi H, Asai N, Saito S, Higuchi T, Kato K, Okumura T, Bando YK, Takefuji M, Mizutani Y, Miyai Y, Saito S, Maruyama S, Maeda K, Ouchi N, Nagasaka A, Miyata T, Mii S, Kioka N, Worthley DL, Murohara T, Takahashi M, Enomoto A.

Circ Res. 2019 Aug 2;125(4):414-430. doi: 10.1161/CIRCRESAHA.119.314806. Epub 2019 Jun 21.

PMID:
31221024
3.

Cardiomyocytes capture stem cell-derived, anti-apoptotic microRNA-214 via clathrin-mediated endocytosis in acute myocardial infarction.

Eguchi S, Takefuji M, Sakaguchi T, Ishihama S, Mori Y, Tsuda T, Takikawa T, Yoshida T, Ohashi K, Shimizu Y, Hayashida R, Kondo K, Bando YK, Ouchi N, Murohara T.

J Biol Chem. 2019 Aug 2;294(31):11665-11674. doi: 10.1074/jbc.RA119.007537. Epub 2019 Jun 19.

PMID:
31217281
4.

Associations among circulating levels of follistatin-like 1, clinical parameters, and cardiovascular events in patients undergoing elective percutaneous coronary intervention with drug-eluting stents.

Aikawa T, Shimada K, Miyauchi K, Miyazaki T, Sai E, Ouchi S, Kadoguchi T, Kunimoto M, Joki Y, Dohi T, Okazaki S, Isoda K, Ohashi K, Murohara T, Ouchi N, Daida H.

PLoS One. 2019 Apr 29;14(4):e0216297. doi: 10.1371/journal.pone.0216297. eCollection 2019.

5.

Successful Management of Complicated Uterine Displacement Caused by Unilateral Incarceration of the Bicornuate Uterus.

Ouchi N, Kuwabara Y, Yonezawa M, Kurashina R, Ichikawa T, Sawa R, Takeshita T.

Case Rep Obstet Gynecol. 2019 Mar 7;2019:3205610. doi: 10.1155/2019/3205610. eCollection 2019.

6.

Adipolin/CTRP12 protects against pathological vascular remodeling through suppression of smooth muscle cell growth and macrophage inflammatory response.

Ogawa H, Ohashi K, Ito M, Shibata R, Kanemura N, Yuasa D, Kambara T, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Otaka N, Kawanishi H, Yamaguchi S, Enomoto T, Abe T, Kaneko M, Takefuji M, Murohara T, Ouchi N.

Cardiovasc Res. 2019 Mar 15. pii: cvz074. doi: 10.1093/cvr/cvz074. [Epub ahead of print]

PMID:
30874788
7.

Myonectin Is an Exercise-Induced Myokine That Protects the Heart From Ischemia-Reperfusion Injury.

Otaka N, Shibata R, Ohashi K, Uemura Y, Kambara T, Enomoto T, Ogawa H, Ito M, Kawanishi H, Maruyama S, Joki Y, Fujikawa Y, Narita S, Unno K, Kawamoto Y, Murate T, Murohara T, Ouchi N.

Circ Res. 2018 Dec 7;123(12):1326-1338. doi: 10.1161/CIRCRESAHA.118.313777.

PMID:
30566056
8.

Determination of an accurate size distribution of nanoparticles using particle tracking analysis corrected for the adverse effect of random Brownian motion.

Matsuura Y, Ouchi N, Nakamura A, Kato H.

Phys Chem Chem Phys. 2018 Jul 4;20(26):17839-17846. doi: 10.1039/c7cp08332g.

PMID:
29923555
9.

Adiponectin/AdiopR1 signal inactivation contributes to impaired angiogenesis in mice of advanced age.

Piao L, Yu C, Xu W, Inoue A, Shibata R, Li X, Nan Y, Zhao G, Wang H, Meng X, Lei Y, Goto H, Ouchi N, Murohara T, Kuzuya M, Cheng XW.

Int J Cardiol. 2018 Sep 15;267:150-155. doi: 10.1016/j.ijcard.2018.05.089. Epub 2018 May 24.

PMID:
29861101
10.

Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis.

Piao L, Zhao G, Zhu E, Inoue A, Shibata R, Lei Y, Hu L, Yu C, Yang G, Wu H, Xu W, Okumura K, Ouchi N, Murohara T, Kuzuya M, Cheng XW.

J Am Heart Assoc. 2017 Sep 28;6(10). pii: e006421. doi: 10.1161/JAHA.117.006421.

11.

Diversity of progesterone action on lipopolysaccharide-induced expression changes in cultured human cervical fibroblasts according to inflammation and treatment timing.

Kuwabara Y, Katayama A, Kurihara S, Ito M, Yonezawa M, Ouchi N, Kurashina R, Ichikawa T, Sawa R, Nakai A, Orimo H, Takeshita T.

Am J Reprod Immunol. 2017 Nov;78(5). doi: 10.1111/aji.12731. Epub 2017 Aug 1.

PMID:
28762599
12.

Role of Adipokines in Cardiovascular Disease.

Lau WB, Ohashi K, Wang Y, Ogawa H, Murohara T, Ma XL, Ouchi N.

Circ J. 2017 Jun 23;81(7):920-928. doi: 10.1253/circj.CJ-17-0458. Epub 2017 Jun 10. Review.

13.

The role of adipokines in cardiovascular disease.

Shibata R, Ouchi N, Ohashi K, Murohara T.

J Cardiol. 2017 Oct;70(4):329-334. doi: 10.1016/j.jjcc.2017.02.006. Epub 2017 Mar 18. Review.

14.

Extrahepatic bile duct hepatocellular carcinoma due to recurrence of hematogenous metastasis 50 months after hepatectomy.

Kumata H, Miyagi S, Murakami K, Fujio A, Hara Y, Nakanishi C, Kawagishi N, Sasano H, Kamei T, Ouchi N.

Surg Case Rep. 2017 Dec;3(1):30. doi: 10.1186/s40792-017-0305-3. Epub 2017 Feb 16.

15.

C1q/TNF-related protein 1 prevents neointimal formation after arterial injury.

Kanemura N, Shibata R, Ohashi K, Ogawa H, Hiramatsu-Ito M, Enomoto T, Yuasa D, Ito M, Hayakawa S, Otaka N, Murohara T, Ouchi N.

Atherosclerosis. 2017 Feb;257:138-145. doi: 10.1016/j.atherosclerosis.2017.01.014. Epub 2017 Jan 16.

PMID:
28131048
16.

Protective Roles of Adipocytokines and Myokines in Cardiovascular Disease.

Ouchi N, Ohashi K, Shibata R, Murohara T.

Circ J. 2016 Sep 23;80(10):2073-80. doi: 10.1253/circj.CJ-16-0663. Epub 2016 Sep 1. Review.

17.

Increased expression of the adipocytokine omentin in the epicardial adipose tissue of coronary artery disease patients.

Harada K, Shibata R, Ouchi N, Tokuda Y, Funakubo H, Suzuki M, Kataoka T, Nagao T, Okumura S, Shinoda N, Kato B, Sakai S, Kato M, Marui N, Ishii H, Amano T, Matsubara T, Murohara T.

Atherosclerosis. 2016 Aug;251:299-304. doi: 10.1016/j.atherosclerosis.2016.07.003. Epub 2016 Jul 6.

PMID:
27450783
18.

Follistatin like 1 Regulates Hypertrophy in Heart Failure with Preserved Ejection Fraction.

Tanaka K, Valero-Muñoz M, Wilson RM, Essick EE, Fowler CT, Nakamura K, van den Hoff M, Ouchi N, Sam F.

JACC Basic Transl Sci. 2016 Jun;1(4):207-221. doi: 10.1016/j.jacbts.2016.04.002. Epub 2016 Jun 27.

19.

Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture.

Maruyama S, Nakamura K, Papanicolaou KN, Sano S, Shimizu I, Asaumi Y, van den Hoff MJ, Ouchi N, Recchia FA, Walsh K.

EMBO Mol Med. 2016 Aug 1;8(8):949-66. doi: 10.15252/emmm.201506151. Print 2016 Aug.

20.

Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease.

Fuster JJ, Ouchi N, Gokce N, Walsh K.

Circ Res. 2016 May 27;118(11):1786-807. doi: 10.1161/CIRCRESAHA.115.306885. Review.

21.

Association of Circulating Follistatin-Like 1 Levels with Inflammatory and Oxidative Stress Markers in Healthy Men.

Hayakawa S, Ohashi K, Shibata R, Takahashi R, Otaka N, Ogawa H, Ito M, Kanemura N, Hiramatsu-Ito M, Ikeda N, Murohara T, Ouchi N.

PLoS One. 2016 May 4;11(5):e0153619. doi: 10.1371/journal.pone.0153619. eCollection 2016.

22.

Adipocytokines in Cardiovascular and Metabolic Diseases.

Ouchi N.

J Atheroscler Thromb. 2016 Jun 1;23(6):645-54. doi: 10.5551/jat.34918. Epub 2016 Apr 16. Review.

23.

[Omentin and cardiovascular disease].

Shibata R, Ouchi N, Murohara T.

Nihon Yakurigaku Zasshi. 2016 Mar;147(3):139-42. doi: 10.1254/fpj.147.139. Japanese. No abstract available.

PMID:
26960772
24.

Intratumoral estrogen production and actions in luminal A type invasive lobular and ductal carcinomas.

Takagi M, Miki Y, Miyashita M, Hata S, Yoda T, Hirakawa H, Sagara Y, Rai Y, Ohi Y, Tamaki K, Ishida T, Suzuki T, Ouchi N, Sasano H.

Breast Cancer Res Treat. 2016 Feb;156(1):45-55. doi: 10.1007/s10549-016-3739-6. Epub 2016 Mar 4.

PMID:
26943913
25.

Omentin attenuates atherosclerotic lesion formation in apolipoprotein E-deficient mice.

Hiramatsu-Ito M, Shibata R, Ohashi K, Uemura Y, Kanemura N, Kambara T, Enomoto T, Yuasa D, Matsuo K, Ito M, Hayakawa S, Ogawa H, Otaka N, Kihara S, Murohara T, Ouchi N.

Cardiovasc Res. 2016 May 1;110(1):107-17. doi: 10.1093/cvr/cvv282. Epub 2015 Dec 28.

PMID:
26714927
26.

Secreted Frizzled-related Protein 5 Diminishes Cardiac Inflammation and Protects the Heart from Ischemia/Reperfusion Injury.

Nakamura K, Sano S, Fuster JJ, Kikuchi R, Shimizu I, Ohshima K, Katanasaka Y, Ouchi N, Walsh K.

J Biol Chem. 2016 Feb 5;291(6):2566-75. doi: 10.1074/jbc.M115.693937. Epub 2015 Dec 2.

27.

C1q/TNF-related protein-1 functions to protect against acute ischemic injury in the heart.

Yuasa D, Ohashi K, Shibata R, Mizutani N, Kataoka Y, Kambara T, Uemura Y, Matsuo K, Kanemura N, Hayakawa S, Hiramatsu-Ito M, Ito M, Ogawa H, Murate T, Murohara T, Ouchi N.

FASEB J. 2016 Mar;30(3):1065-75. doi: 10.1096/fj.15-279885. Epub 2015 Nov 17.

PMID:
26578687
28.

C1q/Tumor Necrosis Factor-Related Protein 9 Protects against Acute Myocardial Injury through an Adiponectin Receptor I-AMPK-Dependent Mechanism.

Kambara T, Shibata R, Ohashi K, Matsuo K, Hiramatsu-Ito M, Enomoto T, Yuasa D, Ito M, Hayakawa S, Ogawa H, Aprahamian T, Walsh K, Murohara T, Ouchi N.

Mol Cell Biol. 2015 Jun;35(12):2173-85. doi: 10.1128/MCB.01518-14. Epub 2015 Apr 13.

29.

Adiponectin as a Target in Obesity-related Inflammatory State.

Ohashi K, Yuasa D, Shibata R, Murohara T, Ouchi N.

Endocr Metab Immune Disord Drug Targets. 2015;15(2):145-50. Review.

PMID:
25772181
30.

FGF21 attenuates pathological myocardial remodeling following myocardial infarction through the adiponectin-dependent mechanism.

Joki Y, Ohashi K, Yuasa D, Shibata R, Ito M, Matsuo K, Kambara T, Uemura Y, Hayakawa S, Hiramatsu-Ito M, Kanemura N, Ogawa H, Daida H, Murohara T, Ouchi N.

Biochem Biophys Res Commun. 2015 Mar 27;459(1):124-30. doi: 10.1016/j.bbrc.2015.02.081. Epub 2015 Feb 21.

PMID:
25712519
31.

Neuron-derived neurotrophic factor ameliorates adverse cardiac remodeling after experimental myocardial infarction.

Joki Y, Ohashi K, Yuasa D, Shibata R, Kataoka Y, Kambara T, Uemura Y, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Kanemura N, Ito M, Ogawa H, Daida H, Murohara T, Ouchi N.

Circ Heart Fail. 2015 Mar;8(2):342-51. doi: 10.1161/CIRCHEARTFAILURE.114.001647. Epub 2015 Feb 5.

PMID:
25654972
32.

Secreted frizzled-related protein 5 (Sfrp5) decreases hepatic stellate cell activation and liver fibrosis.

Chatani N, Kamada Y, Kizu T, Ogura S, Furuta K, Egawa M, Hamano M, Ezaki H, Kiso S, Shimono A, Ouchi N, Yoshida Y, Takehara T.

Liver Int. 2015 Aug;35(8):2017-26. doi: 10.1111/liv.12757. Epub 2015 Jan 20.

PMID:
25488180
33.

Omentin functions to attenuate cardiac hypertrophic response.

Matsuo K, Shibata R, Ohashi K, Kambara T, Uemura Y, Hiramatsu-Ito M, Enomoto T, Yuasa D, Joki Y, Ito M, Hayakawa S, Ogawa H, Kihara S, Murohara T, Ouchi N.

J Mol Cell Cardiol. 2015 Feb;79:195-202. doi: 10.1016/j.yjmcc.2014.11.019. Epub 2014 Dec 3.

PMID:
25479337
34.

Adipose-derived protein omentin prevents neointimal formation after arterial injury.

Uemura Y, Shibata R, Kanemura N, Ohashi K, Kambara T, Hiramatsu-Ito M, Enomoto T, Yuasa D, Joki Y, Matsuo K, Ito M, Hayakawa S, Ogawa H, Murohara T, Ouchi N.

FASEB J. 2015 Jan;29(1):141-51. doi: 10.1096/fj.14-258129. Epub 2014 Oct 9.

PMID:
25300621
35.

Adiponectin ameliorates endotoxin-induced acute cardiac injury.

Watanabe Y, Shibata R, Ouchi N, Kambara T, Ohashi K, Jie L, Inoue Y, Murohara T, Komori K.

Biomed Res Int. 2014;2014:382035. doi: 10.1155/2014/382035. Epub 2014 Aug 10.

36.

Effects of adiponectin on calcium-handling proteins in heart failure with preserved ejection fraction.

Tanaka K, Wilson RM, Essick EE, Duffen JL, Scherer PE, Ouchi N, Sam F.

Circ Heart Fail. 2014 Nov;7(6):976-85. doi: 10.1161/CIRCHEARTFAILURE.114.001279. Epub 2014 Aug 22.

37.

Vildagliptin stimulates endothelial cell network formation and ischemia-induced revascularization via an endothelial nitric-oxide synthase-dependent mechanism.

Ishii M, Shibata R, Kondo K, Kambara T, Shimizu Y, Tanigawa T, Bando YK, Nishimura M, Ouchi N, Murohara T.

J Biol Chem. 2014 Sep 26;289(39):27235-45. doi: 10.1074/jbc.M114.557835. Epub 2014 Aug 6.

38.

Cardiac myocyte-derived follistatin-like 1 prevents renal injury in a subtotal nephrectomy model.

Hayakawa S, Ohashi K, Shibata R, Kataoka Y, Miyabe M, Enomoto T, Joki Y, Shimizu Y, Kambara T, Uemura Y, Yuasa D, Ogawa H, Matsuo K, Hiramatsu-Ito M, van den Hoff MJ, Walsh K, Murohara T, Ouchi N.

J Am Soc Nephrol. 2015 Mar;26(3):636-46. doi: 10.1681/ASN.2014020210. Epub 2014 Jul 28.

39.

The potential of adipokines as therapeutic agents for cardiovascular disease.

Shibata R, Ohashi K, Murohara T, Ouchi N.

Cytokine Growth Factor Rev. 2014 Aug;25(4):483-7. doi: 10.1016/j.cytogfr.2014.07.005. Epub 2014 Jul 11. Review.

PMID:
25066649
40.

Multilayered adipose-derived regenerative cell sheets created by a novel magnetite tissue engineering method for myocardial infarction.

Ishii M, Shibata R, Shimizu Y, Yamamoto T, Kondo K, Inoue Y, Ouchi N, Tanigawa T, Kanemura N, Ito A, Honda H, Murohara T.

Int J Cardiol. 2014 Aug 20;175(3):545-53. doi: 10.1016/j.ijcard.2014.06.034. Epub 2014 Jul 2.

PMID:
25023793
41.

Metformin stimulates ischemia-induced revascularization through an eNOS dependent pathway in the ischemic hindlimb mice model.

Takahashi N, Shibata R, Ouchi N, Sugimoto M, Murohara T, Komori K.

J Vasc Surg. 2015 Feb;61(2):489-96. doi: 10.1016/j.jvs.2013.09.061. Epub 2014 Jul 1.

42.

Association of circulating C1q/TNF-related protein 1 levels with coronary artery disease in men.

Yuasa D, Ohashi K, Shibata R, Takeshita K, Kikuchi R, Takahashi R, Kataoka Y, Miyabe M, Joki Y, Kambara T, Uemura Y, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Ito M, Ikeda N, Murohara T, Ouchi N.

PLoS One. 2014 Jun 19;9(6):e99846. doi: 10.1371/journal.pone.0099846. eCollection 2014.

43.

Omentin prevents myocardial ischemic injury through AMP-activated protein kinase- and Akt-dependent mechanisms.

Kataoka Y, Shibata R, Ohashi K, Kambara T, Enomoto T, Uemura Y, Ogura Y, Yuasa D, Matsuo K, Nagata T, Oba T, Yasukawa H, Numaguchi Y, Sone T, Murohara T, Ouchi N.

J Am Coll Cardiol. 2014 Jun 24;63(24):2722-33. doi: 10.1016/j.jacc.2014.03.032. Epub 2014 Apr 23.

44.

Adiponectin deficiency exacerbates age-related hearing impairment.

Tanigawa T, Shibata R, Ouchi N, Kondo K, Ishii M, Katahira N, Kambara T, Inoue Y, Takahashi R, Ikeda N, Kihara S, Ueda H, Murohara T.

Cell Death Dis. 2014 Apr 24;5:e1189. doi: 10.1038/cddis.2014.140.

45.

Role of anti-inflammatory adipokines in obesity-related diseases.

Ohashi K, Shibata R, Murohara T, Ouchi N.

Trends Endocrinol Metab. 2014 Jul;25(7):348-55. doi: 10.1016/j.tem.2014.03.009. Epub 2014 Apr 17. Review.

PMID:
24746980
46.

Muscle-derived follistatin-like 1 functions to reduce neointimal formation after vascular injury.

Miyabe M, Ohashi K, Shibata R, Uemura Y, Ogura Y, Yuasa D, Kambara T, Kataoka Y, Yamamoto T, Matsuo K, Joki Y, Enomoto T, Hayakawa S, Hiramatsu-Ito M, Ito M, Van Den Hoff MJ, Walsh K, Murohara T, Ouchi N.

Cardiovasc Res. 2014 Jul 1;103(1):111-20. doi: 10.1093/cvr/cvu105. Epub 2014 Apr 17.

47.

Neuron-derived neurotrophic factor functions as a novel modulator that enhances endothelial cell function and revascularization processes.

Ohashi K, Enomoto T, Joki Y, Shibata R, Ogura Y, Kataoka Y, Shimizu Y, Kambara T, Uemura Y, Yuasa D, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Murohara T, Ouchi N.

J Biol Chem. 2014 May 16;289(20):14132-44. doi: 10.1074/jbc.M114.555789. Epub 2014 Apr 6.

48.

Transcriptional regulation of an insulin-sensitizing adipokine adipolin/CTRP12 in adipocytes by Krüppel-like factor 15.

Enomoto T, Ohashi K, Shibata R, Kambara T, Uemura Y, Yuasa D, Kataoka Y, Miyabe M, Matsuo K, Joki Y, Hayakawa S, Hiramatsu-Ito M, Ito M, Murohara T, Ouchi N.

PLoS One. 2013 Dec 16;8(12):e83183. doi: 10.1371/journal.pone.0083183. eCollection 2013.

49.

Recurrence of ovarian endometrioma after laparoscopic excision: risk factors and prevention.

Ouchi N, Akira S, Mine K, Ichikawa M, Takeshita T.

J Obstet Gynaecol Res. 2014 Jan;40(1):230-6. doi: 10.1111/jog.12164. Epub 2013 Sep 19.

PMID:
24102958
50.

Adiponectin-mediated modulation of lymphatic vessel formation and lymphedema.

Shimizu Y, Shibata R, Ishii M, Ohashi K, Kambara T, Uemura Y, Yuasa D, Kataoka Y, Kihara S, Murohara T, Ouchi N.

J Am Heart Assoc. 2013 Sep 19;2(5):e000438. doi: 10.1161/JAHA.113.000438.

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