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Items: 1 to 50 of 125

1.

New antimicrobials targeting bacterial RNA polymerase holoenzyme assembly identified with an in vivo BRET-based discovery platform.

Sartini S, Levati E, Maccesi M, Guerra M, Spadoni G, Bach S, Benincasa M, Scocchi M, Ottonello S, Rivara S, Montanini B.

ACS Chem Biol. 2019 Jul 16. doi: 10.1021/acschembio.9b00178. [Epub ahead of print]

PMID:
31310497
2.

Influence of Vitamin D in Advanced Non-Small Cell Lung Cancer Patients Treated with Nivolumab.

Cusato J, Genova C, Tomasello C, Carrega P, Ottonello S, Pietra G, Mingari MC, Cossu I, Rijavec E, Leggieri A, Di Perri G, Dal Bello MG, Coco S, Boccardo S, Ferlazzo G, Grossi F, D'Avolio A.

Cancers (Basel). 2019 Jan 21;11(1). pii: E125. doi: 10.3390/cancers11010125.

3.

Pezizomycetes genomes reveal the molecular basis of ectomycorrhizal truffle lifestyle.

Murat C, Payen T, Noel B, Kuo A, Morin E, Chen J, Kohler A, Krizsán K, Balestrini R, Da Silva C, Montanini B, Hainaut M, Levati E, Barry KW, Belfiori B, Cichocki N, Clum A, Dockter RB, Fauchery L, Guy J, Iotti M, Le Tacon F, Lindquist EA, Lipzen A, Malagnac F, Mello A, Molinier V, Miyauchi S, Poulain J, Riccioni C, Rubini A, Sitrit Y, Splivallo R, Traeger S, Wang M, Žifčáková L, Wipf D, Zambonelli A, Paolocci F, Nowrousian M, Ottonello S, Baldrian P, Spatafora JW, Henrissat B, Nagy LG, Aury JM, Wincker P, Grigoriev IV, Bonfante P, Martin FM.

Nat Ecol Evol. 2018 Dec;2(12):1956-1965. doi: 10.1038/s41559-018-0710-4. Epub 2018 Nov 12.

4.

Author Correction: A family of archaea-like carboxylesterases preferentially expressed in the symbiotic phase of the mycorrhizal fungus Tuber melanosporum.

Cavazzini D, Grossi G, Levati E, Vallese F, Montanini B, Bolchi A, Zanotti G, Ottonello S.

Sci Rep. 2018 Aug 29;8(1):13173. doi: 10.1038/s41598-018-29606-0.

5.

Doxycycline counteracts neuroinflammation restoring memory in Alzheimer's disease mouse models.

Balducci C, Santamaria G, La Vitola P, Brandi E, Grandi F, Viscomi AR, Beeg M, Gobbi M, Salmona M, Ottonello S, Forloni G.

Neurobiol Aging. 2018 Oct;70:128-139. doi: 10.1016/j.neurobiolaging.2018.06.002. Epub 2018 Jun 12.

PMID:
30007162
6.

Broadly neutralizing antiviral responses induced by a single-molecule HPV vaccine based on thermostable thioredoxin-L2 multiepitope nanoparticles.

Spagnoli G, Pouyanfard S, Cavazzini D, Canali E, Maggi S, Tommasino M, Bolchi A, Müller M, Ottonello S.

Sci Rep. 2017 Dec 21;7(1):18000. doi: 10.1038/s41598-017-18177-1.

7.

Minor Capsid Protein L2 Polytope Induces Broad Protection against Oncogenic and Mucosal Human Papillomaviruses.

Pouyanfard S, Spagnoli G, Bulli L, Balz K, Yang F, Odenwald C, Seitz H, Mariz FC, Bolchi A, Ottonello S, Müller M.

J Virol. 2018 Jan 30;92(4). pii: e01930-17. doi: 10.1128/JVI.01930-17. Print 2018 Feb 15.

8.

Induction of Antihuman C-C Chemokine Receptor Type 5 Antibodies by a Bovine Herpesvirus Type-4 Based Vector.

Verna AE, Franceschi V, Tebaldi G, Macchi F, Menozzi V, Pastori C, Lopalco L, Ottonello S, Cavirani S, Donofrio G.

Front Immunol. 2017 Oct 25;8:1402. doi: 10.3389/fimmu.2017.01402. eCollection 2017.

9.

Regulatory networks underlying mycorrhizal development delineated by genome-wide expression profiling and functional analysis of the transcription factor repertoire of the plant symbiotic fungus Laccaria bicolor.

Daguerre Y, Levati E, Ruytinx J, Tisserant E, Morin E, Kohler A, Montanini B, Ottonello S, Brun A, Veneault-Fourrey C, Martin F.

BMC Genomics. 2017 Sep 18;18(1):737. doi: 10.1186/s12864-017-4114-7.

10.

Correction: In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.

Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M.

Elife. 2017 Aug 31;6. pii: e30948. doi: 10.7554/eLife.30948. No abstract available.

11.

A family of archaea-like carboxylesterases preferentially expressed in the symbiotic phase of the mychorrizal fungus Tuber melanosporum.

Cavazzini D, Grossi G, Levati E, Vallese F, Montanini B, Bolchi A, Zanotti G, Ottonello S.

Sci Rep. 2017 Aug 9;7(1):7628. doi: 10.1038/s41598-017-08007-9. Erratum in: Sci Rep. 2018 Aug 29;8(1):13173.

12.

Synthesis of Fluorescent Core-Shell Metal Nanohybrids: A Versatile Approach.

Alloisio M, Rusu M, Ottonello S, Ottonelli M, Thea S, Comoretto D.

Materials (Basel). 2016 Dec 9;9(12). pii: E997. doi: 10.3390/ma9120997.

13.

Photoreceptors in the dark: A functional white collar-like complex and other putative light-sensing components encoded by the genome of the subterranean fungus Tuber melanosporum.

Gerace R, Montanini B, Proietto M, Levati E, De Luca C, Brenna A, Filetici P, Kohler A, Ottonello S, Ballario P.

Fungal Biol. 2017 Mar;121(3):253-263. doi: 10.1016/j.funbio.2016.12.003. Epub 2017 Jan 5.

PMID:
28215352
14.

Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B.

Fisicaro P, Barili V, Montanini B, Acerbi G, Ferracin M, Guerrieri F, Salerno D, Boni C, Massari M, Cavallo MC, Grossi G, Giuberti T, Lampertico P, Missale G, Levrero M, Ottonello S, Ferrari C.

Nat Med. 2017 Mar;23(3):327-336. doi: 10.1038/nm.4275. Epub 2017 Feb 6.

PMID:
28165481
15.

Dry and wet approaches for genome-wide functional annotation of conventional and unconventional transcriptional activators.

Levati E, Sartini S, Ottonello S, Montanini B.

Comput Struct Biotechnol J. 2016 Jun 29;14:262-70. doi: 10.1016/j.csbj.2016.06.004. eCollection 2016. Review.

16.

Virus-Mediated Metalloproteinase 1 Induction Revealed by Transcriptome Profiling of Bovine Herpesvirus 4-Infected Bovine Endometrial Stromal Cells.

Tebaldi G, Jacca S, Montanini B, Capra E, Rosamilia A, Sala A, Stella A, Castiglioni B, Ottonello S, Donofrio G.

Biol Reprod. 2016 Jul;95(1):12. doi: 10.1095/biolreprod.116.139097. Epub 2016 Jun 8.

PMID:
27281703
17.

Bovine herpesvirus 4-based vector delivering a hybrid rat/human HER-2 oncoantigen efficiently protects mice from autochthonous Her-2+ mammary cancer.

Jacca S, Rolih V, Quaglino E, Franceschi V, Tebaldi G, Bolli E, Rosamilia A, Ottonello S, Cavallo F, Donofrio G.

Oncoimmunology. 2015 Aug 31;5(3):e1082705. eCollection 2016 Mar.

18.

Secretory production of designed multipeptides displayed on a thermostable bacterial thioredoxin scaffold in Pichia pastoris.

Spagnoli G, Bolchi A, Cavazzini D, Pouyanfard S, Müller M, Ottonello S.

Protein Expr Purif. 2017 Jan;129:150-157. doi: 10.1016/j.pep.2016.04.012. Epub 2016 Apr 29.

PMID:
27133916
19.

Moonlighting transcriptional activation function of a fungal sulfur metabolism enzyme.

Levati E, Sartini S, Bolchi A, Ottonello S, Montanini B.

Sci Rep. 2016 Apr 28;6:25165. doi: 10.1038/srep25165.

20.

Thioredoxin-Displayed Multipeptide Immunogens.

Bolchi A, Canali E, Santoni A, Spagnoli G, Viarisio D, Accardi R, Tommasino M, Müller M, Ottonello S.

Methods Mol Biol. 2015;1348:137-51. doi: 10.1007/978-1-4939-2999-3_14.

PMID:
26424270
21.

Elongator-dependent modification of cytoplasmic tRNALysUUU is required for mitochondrial function under stress conditions.

Tigano M, Ruotolo R, Dallabona C, Fontanesi F, Barrientos A, Donnini C, Ottonello S.

Nucleic Acids Res. 2015 Sep 30;43(17):8368-80. doi: 10.1093/nar/gkv765. Epub 2015 Aug 3.

22.

Robust In Vitro and In Vivo Neutralization against Multiple High-Risk HPV Types Induced by a Thermostable Thioredoxin-L2 Vaccine.

Seitz H, Ribeiro-Müller L, Canali E, Bolchi A, Tommasino M, Ottonello S, Müller M.

Cancer Prev Res (Phila). 2015 Oct;8(10):932-41. doi: 10.1158/1940-6207.CAPR-15-0164. Epub 2015 Jul 13.

23.

In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.

Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M.

Elife. 2015 Apr 7;4:e06205. doi: 10.7554/eLife.06205. Erratum in: Elife. 2017 Aug 31;6:.

24.

A comprehensive resource of genomic, epigenomic and transcriptomic sequencing data for the black truffle Tuber melanosporum.

Chen PY, Montanini B, Liao WW, Morselli M, Jaroszewicz A, Lopez D, Ottonello S, Pellegrini M.

Gigascience. 2014 Oct 30;3:25. doi: 10.1186/2047-217X-3-25. eCollection 2014.

25.

Non-exhaustive DNA methylation-mediated transposon silencing in the black truffle genome, a complex fungal genome with massive repeat element content.

Montanini B, Chen PY, Morselli M, Jaroszewicz A, Lopez D, Martin F, Ottonello S, Pellegrini M.

Genome Biol. 2014 Jul 31;15(7):411. doi: 10.1186/s13059-014-0411-5.

26.

Alum and squalene-oil-in-water emulsion enhance the titer and avidity of anti-Aβ antibodies induced by multimeric protein antigen (1-11)E2, preserving the Igg1-skewed isotype distribution.

Mantile F, Trovato M, Santoni A, Barba P, Ottonello S, De Berardinis P, Prisco A.

PLoS One. 2014 Jul 1;9(7):e101474. doi: 10.1371/journal.pone.0101474. eCollection 2014.

27.

Integrative gene transfer in the truffle Tuber borchii by Agrobacterium tumefaciens-mediated transformation.

Brenna A, Montanini B, Muggiano E, Proietto M, Filetici P, Ottonello S, Ballario P.

AMB Express. 2014 May 29;4:43. doi: 10.1186/s13568-014-0043-x. eCollection 2014.

28.

A high-performance thioredoxin-based scaffold for peptide immunogen construction: proof-of-concept testing with a human papillomavirus epitope.

Canali E, Bolchi A, Spagnoli G, Seitz H, Rubio I, Pertinhez TA, Müller M, Ottonello S.

Sci Rep. 2014 Apr 22;4:4729. doi: 10.1038/srep04729.

29.

Pharmacological targeting of the β-amyloid precursor protein intracellular domain.

Branca C, Sarnico I, Ruotolo R, Lanzillotta A, Viscomi AR, Benarese M, Porrini V, Lorenzini L, Calzà L, Imbimbo BP, Ottonello S, Pizzi M.

Sci Rep. 2014 Apr 9;4:4618. doi: 10.1038/srep04618.

30.

A three component mix of thioredoxin-L2 antigens elicits broadly neutralizing responses against oncogenic human papillomaviruses.

Seitz H, Canali E, Ribeiro-Müller L, Pàlfi A, Bolchi A, Tommasino M, Ottonello S, Müller M.

Vaccine. 2014 May 7;32(22):2610-7. doi: 10.1016/j.vaccine.2014.03.033. Epub 2014 Mar 21.

PMID:
24662712
31.

Glucuronidation does not suppress the estrogenic activity of quercetin in yeast and human breast cancer cell model systems.

Ruotolo R, Calani L, Brighenti F, Crozier A, Ottonello S, Del Rio D.

Arch Biochem Biophys. 2014 Oct 1;559:62-7. doi: 10.1016/j.abb.2014.03.003. Epub 2014 Mar 18.

PMID:
24657077
32.

Influence of oxidation and multimerization on the immunogenicity of a thioredoxin-l2 prophylactic papillomavirus vaccine.

Seitz H, Dantheny T, Burkart F, Ottonello S, Müller M.

Clin Vaccine Immunol. 2013 Jul;20(7):1061-9. doi: 10.1128/CVI.00195-13. Epub 2013 May 15.

33.

Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice.

Sivilia S, Lorenzini L, Giuliani A, Gusciglio M, Fernandez M, Baldassarro VA, Mangano C, Ferraro L, Pietrini V, Baroc MF, Viscomi AR, Ottonello S, Villetti G, Imbimbo BP, Calzà L, Giardino L.

BMC Neurosci. 2013 Apr 5;14:44. doi: 10.1186/1471-2202-14-44.

34.

Anti-estrogenic activity of a human resveratrol metabolite.

Ruotolo R, Calani L, Fietta E, Brighenti F, Crozier A, Meda C, Maggi A, Ottonello S, Del Rio D.

Nutr Metab Cardiovasc Dis. 2013 Nov;23(11):1086-92. doi: 10.1016/j.numecd.2013.01.002. Epub 2013 Mar 5.

PMID:
23465317
35.

Autoproteolytic Activation of a Symbiosis-regulated Truffle Phospholipase A2.

Cavazzini D, Meschi F, Corsini R, Bolchi A, Rossi GL, Einsle O, Ottonello S.

J Biol Chem. 2013 Jan 18;288(3):1533-47. doi: 10.1074/jbc.M112.384156. Epub 2012 Nov 28.

36.

Trust at first sight: evidence from ERPs.

Marzi T, Righi S, Ottonello S, Cincotta M, Viggiano MP.

Soc Cogn Affect Neurosci. 2014 Jan;9(1):63-72. doi: 10.1093/scan/nss102. Epub 2012 Sep 5.

37.

Solanezumab for the treatment of mild-to-moderate Alzheimer's disease.

Imbimbo BP, Ottonello S, Frisardi V, Solfrizzi V, Greco A, Seripa D, Pilotto A, Panza F.

Expert Rev Clin Immunol. 2012 Feb;8(2):135-49. doi: 10.1586/eci.11.93. Review.

PMID:
22288451
38.

Fearful expressions enhance recognition memory: electrophysiological evidence.

Righi S, Marzi T, Toscani M, Baldassi S, Ottonello S, Viggiano MP.

Acta Psychol (Amst). 2012 Jan;139(1):7-18. doi: 10.1016/j.actpsy.2011.09.015. Epub 2011 Oct 26.

PMID:
22036588
39.

Ability of Bifidobacterium breve to grow on different types of milk: exploring the metabolism of milk through genome analysis.

Turroni F, Foroni E, Serafini F, Viappiani A, Montanini B, Bottacini F, Ferrarini A, Bacchini PL, Rota C, Delledonne M, Ottonello S, van Sinderen D, Ventura M.

Appl Environ Microbiol. 2011 Oct;77(20):7408-17. doi: 10.1128/AEM.05336-11. Epub 2011 Aug 19.

40.

Tapping genomics to unravel ectomycorrhizal symbiosis.

Plett JM, Montanini B, Kohler A, Ottonello S, Martin F.

Methods Mol Biol. 2011;722:249-81. doi: 10.1007/978-1-61779-040-9_19.

PMID:
21590427
41.

Structure-function analysis of a CVNH-LysM lectin expressed during plant infection by the rice blast fungus Magnaporthe oryzae.

Koharudin LM, Viscomi AR, Montanini B, Kershaw MJ, Talbot NJ, Ottonello S, Gronenborn AM.

Structure. 2011 May 11;19(5):662-74. doi: 10.1016/j.str.2011.03.004.

42.

The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.

Balducci C, Mehdawy B, Mare L, Giuliani A, Lorenzini L, Sivilia S, Giardino L, Calzà L, Lanzillotta A, Sarnico I, Pizzi M, Usiello A, Viscomi AR, Ottonello S, Villetti G, Imbimbo BP, Nisticò G, Forloni G, Nisticò R.

J Alzheimers Dis. 2011;24(4):799-816. doi: 10.3233/JAD-2011-101839.

PMID:
21321397
43.

Truffle volatiles: from chemical ecology to aroma biosynthesis.

Splivallo R, Ottonello S, Mello A, Karlovsky P.

New Phytol. 2011 Feb;189(3):688-99. Review.

PMID:
21287717
44.

Swine adipose stromal cells loaded with recombinant bovine herpesvirus 4 virions expressing a foreign antigen induce potent humoral immune responses in pigs.

Donofrio G, Taddei S, Franceschi V, Capocefalo A, Cavirani S, Martinelli N, Ottonello S, Ferrari M.

Vaccine. 2011 Jan 29;29(5):867-72. doi: 10.1016/j.vaccine.2010.11.048. Epub 2010 Nov 27.

PMID:
21115049
45.

Genome-wide inventory of metal homeostasis-related gene products including a functional phytochelatin synthase in the hypogeous mycorrhizal fungus Tuber melanosporum.

Bolchi A, Ruotolo R, Marchini G, Vurro E, di Toppi LS, Kohler A, Tisserant E, Martin F, Ottonello S.

Fungal Genet Biol. 2011 Jun;48(6):573-84. doi: 10.1016/j.fgb.2010.11.003. Epub 2010 Nov 19.

PMID:
21094264
46.

The N-terminal region of the human papillomavirus L2 protein contains overlapping binding sites for neutralizing, cross-neutralizing and non-neutralizing antibodies.

Rubio I, Seitz H, Canali E, Sehr P, Bolchi A, Tommasino M, Ottonello S, Müller M.

Virology. 2011 Jan 20;409(2):348-59. doi: 10.1016/j.virol.2010.10.017. Epub 2010 Nov 11.

47.

Genome-wide search and functional identification of transcription factors in the mycorrhizal fungus Tuber melanosporum.

Montanini B, Levati E, Bolchi A, Kohler A, Morin E, Tisserant E, Martin F, Ottonello S.

New Phytol. 2011 Feb;189(3):736-50. doi: 10.1111/j.1469-8137.2010.03525.x. Epub 2010 Nov 8.

48.

Genomic profiling of carbohydrate metabolism in the ectomycorrhizal fungus Tuber melanosporum.

Ceccaroli P, Buffalini M, Saltarelli R, Barbieri E, Polidori E, Ottonello S, Kohler A, Tisserant E, Martin F, Stocchi V.

New Phytol. 2011 Feb;189(3):751-64. doi: 10.1111/j.1469-8137.2010.03520.x. Epub 2010 Oct 29.

49.

Chemogenomic profiling of the cellular effects associated with histone H3 acetylation impairment by a quinoline-derived compound.

Ruotolo R, Tosi F, Vernarecci S, Ballario P, Mai A, Filetici P, Ottonello S.

Genomics. 2010 Nov;96(5):272-80. doi: 10.1016/j.ygeno.2010.08.005. Epub 2010 Aug 21.

50.

Périgord black truffle genome uncovers evolutionary origins and mechanisms of symbiosis.

Martin F, Kohler A, Murat C, Balestrini R, Coutinho PM, Jaillon O, Montanini B, Morin E, Noel B, Percudani R, Porcel B, Rubini A, Amicucci A, Amselem J, Anthouard V, Arcioni S, Artiguenave F, Aury JM, Ballario P, Bolchi A, Brenna A, Brun A, Buée M, Cantarel B, Chevalier G, Couloux A, Da Silva C, Denoeud F, Duplessis S, Ghignone S, Hilselberger B, Iotti M, Marçais B, Mello A, Miranda M, Pacioni G, Quesneville H, Riccioni C, Ruotolo R, Splivallo R, Stocchi V, Tisserant E, Viscomi AR, Zambonelli A, Zampieri E, Henrissat B, Lebrun MH, Paolocci F, Bonfante P, Ottonello S, Wincker P.

Nature. 2010 Apr 15;464(7291):1033-8. doi: 10.1038/nature08867. Epub 2010 Mar 28.

PMID:
20348908

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