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Items: 1 to 50 of 103

1.

Modelling pathogen load dynamics to elucidate mechanistic determinants of host-Plasmodium falciparum interactions.

Georgiadou A, Lee HJ, Walther M, van Beek AE, Fitriani F, Wouters D, Kuijpers TW, Nwakanma D, D'Alessandro U, Riley EM, Otto TD, Ghani A, Levin M, Coin LJ, Conway DJ, Bretscher MT, Cunnington AJ.

Nat Microbiol. 2019 Jun 17. doi: 10.1038/s41564-019-0474-x. [Epub ahead of print]

PMID:
31209307
2.

Progression of the canonical reference malaria parasite genome from 2002-2019.

Böhme U, Otto TD, Sanders M, Newbold CI, Berriman M.

Version 2. Wellcome Open Res. 2019 May 28 [revised 2019 Jan 1];4:58. doi: 10.12688/wellcomeopenres.15194.2. eCollection 2019.

3.

An experimental human blood stage model for studying Plasmodium malariae infection.

Woodford J, Collins KA, Odedra A, Wang C, Kyung JI, Domingo GJ, Watts R, Marquart L, Berriman M, Otto TD, McCarthy JS.

J Infect Dis. 2019 Mar 10. pii: jiz102. doi: 10.1093/infdis/jiz102. [Epub ahead of print]

PMID:
30852586
4.

Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator.

Abdallah AM, Weerdenburg EM, Guan Q, Ummels R, Borggreve S, Adroub SA, Malas TB, Naeem R, Zhang H, Otto TD, Bitter W, Pain A.

PLoS One. 2019 Jan 23;14(1):e0211003. doi: 10.1371/journal.pone.0211003. eCollection 2019.

5.

Low sulfated heparins target multiple proteins for central nervous system repair.

McCanney GA, McGrath MA, Otto TD, Burchmore R, Yates EA, Bavington CD, Willison HJ, Turnbull JE, Barnett SC.

Glia. 2019 Apr;67(4):668-687. doi: 10.1002/glia.23562. Epub 2018 Dec 26.

6.

Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum.

Tarr SJ, Díaz-Ingelmo O, Stewart LB, Hocking SE, Murray L, Duffy CW, Otto TD, Chappell L, Rayner JC, Awandare GA, Conway DJ.

BMC Genomics. 2018 Dec 10;19(1):894. doi: 10.1186/s12864-018-5257-x.

7.

Pre-clinical evaluation of a P. berghei-based whole-sporozoite malaria vaccine candidate.

Mendes AM, Reuling IJ, Andrade CM, Otto TD, Machado M, Teixeira F, Pissarra J, Gonçalves-Rosa N, Bonaparte D, Sinfrónio J, Sanders M, Janse CJ, Khan SM, Newbold CI, Berriman M, Lee CK, Wu Y, Ockenhouse CF, Sauerwein RW, Prudêncio M.

NPJ Vaccines. 2018 Nov 27;3:54. doi: 10.1038/s41541-018-0091-3. eCollection 2018.

8.

A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways.

Campino S, Marin-Menendez A, Kemp A, Cross N, Drought L, Otto TD, Benavente ED, Ravenhall M, Schwach F, Girling G, Manske M, Theron M, Gould K, Drury E, Clark TG, Kwiatkowski DP, Pance A, Rayner JC.

PLoS Pathog. 2018 Nov 29;14(11):e1007436. doi: 10.1371/journal.ppat.1007436. eCollection 2018 Nov.

9.

Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development.

Duffy CW, Amambua-Ngwa A, Ahouidi AD, Diakite M, Awandare GA, Ba H, Tarr SJ, Murray L, Stewart LB, D'Alessandro U, Otto TD, Kwiatkowski DP, Conway DJ.

Sci Rep. 2018 Oct 25;8(1):15763. doi: 10.1038/s41598-018-34078-3.

11.

Genome organization and DNA accessibility control antigenic variation in trypanosomes.

Müller LSM, Cosentino RO, Förstner KU, Guizetti J, Wedel C, Kaplan N, Janzen CJ, Arampatzi P, Vogel J, Steinbiss S, Otto TD, Saliba AE, Sebra RP, Siegel TN.

Nature. 2018 Nov;563(7729):121-125. doi: 10.1038/s41586-018-0619-8. Epub 2018 Oct 17.

PMID:
30333624
12.

Plasmodium vivax-like genome sequences shed new insights into Plasmodium vivax biology and evolution.

Gilabert A, Otto TD, Rutledge GG, Franzon B, Ollomo B, Arnathau C, Durand P, Moukodoum ND, Okouga AP, Ngoubangoye B, Makanga B, Boundenga L, Paupy C, Renaud F, Prugnolle F, Rougeron V.

PLoS Biol. 2018 Aug 24;16(8):e2006035. doi: 10.1371/journal.pbio.2006035. eCollection 2018 Aug.

13.

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.

Wyllie S, Thomas M, Patterson S, Crouch S, De Rycker M, Lowe R, Gresham S, Urbaniak MD, Otto TD, Stojanovski L, Simeons FRC, Manthri S, MacLean LM, Zuccotto F, Homeyer N, Pflaumer H, Boesche M, Sastry L, Connolly P, Albrecht S, Berriman M, Drewes G, Gray DW, Ghidelli-Disse S, Dixon S, Fiandor JM, Wyatt PG, Ferguson MAJ, Fairlamb AH, Miles TJ, Read KD, Gilbert IH.

Nature. 2018 Aug;560(7717):192-197. doi: 10.1038/s41586-018-0356-z. Epub 2018 Jul 25.

14.

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria.

Lee HJ, Georgiadou A, Walther M, Nwakanma D, Stewart LB, Levin M, Otto TD, Conway DJ, Coin LJ, Cunnington AJ.

Sci Transl Med. 2018 Jun 27;10(447). pii: eaar3619. doi: 10.1126/scitranslmed.aar3619.

15.

Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres.

Otto TD, Böhme U, Sanders M, Reid A, Bruske EI, Duffy CW, Bull PC, Pearson RD, Abdi A, Dimonte S, Stewart LB, Campino S, Kekre M, Hamilton WL, Claessens A, Volkman SK, Ndiaye D, Amambua-Ngwa A, Diakite M, Fairhurst RM, Conway DJ, Franck M, Newbold CI, Berriman M.

Wellcome Open Res. 2018 May 3;3:52. doi: 10.12688/wellcomeopenres.14571.1. eCollection 2018.

16.

Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria.

Otto TD, Gilabert A, Crellen T, Böhme U, Arnathau C, Sanders M, Oyola SO, Okouga AP, Boundenga L, Willaume E, Ngoubangoye B, Moukodoum ND, Paupy C, Durand P, Rougeron V, Ollomo B, Renaud F, Newbold C, Berriman M, Prugnolle F.

Nat Microbiol. 2018 Jun;3(6):687-697. doi: 10.1038/s41564-018-0162-2. Epub 2018 May 21.

17.

Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis.

Zhang M, Wang C, Otto TD, Oberstaller J, Liao X, Adapa SR, Udenze K, Bronner IF, Casandra D, Mayho M, Brown J, Li S, Swanson J, Rayner JC, Jiang RHY, Adams JH.

Science. 2018 May 4;360(6388). pii: eaap7847. doi: 10.1126/science.aap7847.

18.

Transcriptomic Studies of Malaria: a Paradigm for Investigation of Systemic Host-Pathogen Interactions.

Lee HJ, Georgiadou A, Otto TD, Levin M, Coin LJ, Conway DJ, Cunnington AJ.

Microbiol Mol Biol Rev. 2018 Apr 25;82(2). pii: e00071-17. doi: 10.1128/MMBR.00071-17. Print 2018 Jun. Review.

19.

Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals.

Böhme U, Otto TD, Cotton JA, Steinbiss S, Sanders M, Oyola SO, Nicot A, Gandon S, Patra KP, Herd C, Bushell E, Modrzynska KK, Billker O, Vinetz JM, Rivero A, Newbold CI, Berriman M.

Genome Res. 2018 Apr;28(4):547-560. doi: 10.1101/gr.218123.116. Epub 2018 Mar 2.

20.

In silico guided reconstruction and analysis of ICAM-1-binding var genes from Plasmodium falciparum.

Carrington E, Otto TD, Szestak T, Lennartz F, Higgins MK, Newbold CI, Craig AG.

Sci Rep. 2018 Feb 19;8(1):3282. doi: 10.1038/s41598-018-21591-8.

21.

Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach.

Kumar K, Srinivasan P, Nold MJ, Moch JK, Reiter K, Sturdevant D, Otto TD, Squires RB, Herrera R, Nagarajan V, Rayner JC, Porcella SF, Geromanos SJ, Haynes JD, Narum DL.

Sci Rep. 2017 Dec 7;7(1):17146. doi: 10.1038/s41598-017-17505-9.

22.

An improved Plasmodium cynomolgi genome assembly reveals an unexpected methyltransferase gene expansion.

Pasini EM, Böhme U, Rutledge GG, Voorberg-Van der Wel A, Sanders M, Berriman M, Kocken CH, Otto TD.

Wellcome Open Res. 2017 Jun 16;2:42. doi: 10.12688/wellcomeopenres.11864.1. eCollection 2017.

23.

Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies.

Payne RO, Silk SE, Elias SC, Milne KH, Rawlinson TA, Llewellyn D, Shakri AR, Jin J, Labbé GM, Edwards NJ, Poulton ID, Roberts R, Farid R, Jørgensen T, Alanine DG, de Cassan SC, Higgins MK, Otto TD, McCarthy JS, de Jongh WA, Nicosia A, Moyle S, Hill AV, Berrie E, Chitnis CE, Lawrie AM, Draper SJ.

JCI Insight. 2017 Jun 15;2(12). pii: 93683. doi: 10.1172/jci.insight.93683. eCollection 2017 Jun 15.

24.

Genomic Characterization of Recrudescent Plasmodium malariae after Treatment with Artemether/Lumefantrine.

Rutledge GG, Marr I, Huang GKL, Auburn S, Marfurt J, Sanders M, White NJ, Berriman M, Newbold CI, Anstey NM, Otto TD, Price RN.

Emerg Infect Dis. 2017 Aug;23(8):1300-1307. doi: 10.3201/eid2308.161582. Epub 2017 Aug 15.

25.

Erratum: SC83288 is a clinical development candidate for the treatment of severe malaria.

Pegoraro S, Duffey M, Otto TD, Wang Y, Rösemann R, Baumgartner R, Fehler SK, Lucantoni L, Avery VM, Moreno-Sabater A, Mazier D, Vial HJ, Strobl S, Sanchez CP, Lanzer M.

Nat Commun. 2017 Apr 6;8:15273. doi: 10.1038/ncomms15273. No abstract available.

26.

Robust high-throughput prokaryote de novo assembly and improvement pipeline for Illumina data.

Page AJ, De Silva N, Hunt M, Quail MA, Parkhill J, Harris SR, Otto TD, Keane JA.

Microb Genom. 2016 Aug 25;2(8):e000083. doi: 10.1099/mgen.0.000083. eCollection 2016 Aug.

27.

SC83288 is a clinical development candidate for the treatment of severe malaria.

Pegoraro S, Duffey M, Otto TD, Wang Y, Rösemann R, Baumgartner R, Fehler SK, Lucantoni L, Avery VM, Moreno-Sabater A, Mazier D, Vial HJ, Strobl S, Sanchez CP, Lanzer M.

Nat Commun. 2017 Jan 31;8:14193. doi: 10.1038/ncomms14193.

28.

pfk13-Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom.

Sutherland CJ, Lansdell P, Sanders M, Muwanguzi J, van Schalkwyk DA, Kaur H, Nolder D, Tucker J, Bennett HM, Otto TD, Berriman M, Patel TA, Lynn R, Gkrania-Klotsas E, Chiodini PL.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e02382-16. doi: 10.1128/AAC.02382-16. Print 2017 Mar.

29.

Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution.

Rutledge GG, Böhme U, Sanders M, Reid AJ, Cotton JA, Maiga-Ascofare O, Djimdé AA, Apinjoh TO, Amenga-Etego L, Manske M, Barnwell JW, Renaud F, Ollomo B, Prugnolle F, Anstey NM, Auburn S, Price RN, McCarthy JS, Kwiatkowski DP, Newbold CI, Berriman M, Otto TD.

Nature. 2017 Feb 2;542(7639):101-104. doi: 10.1038/nature21038. Epub 2017 Jan 25.

30.

Correction: Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole.

Fougère A, Jackson AP, Bechtsi DP, Braks JA, Annoura T, Fonager J, Spaccapelo R, Ramesar J, Chevalley-Maurel S, Klop O, van der Laan AM, Tanke HJ, Kocken CH, Pasini EM, Khan SM, Böhme U, van Ooij C, Otto TD, Janse CJ, Franke-Fayard B.

PLoS Pathog. 2017 Jan 17;13(1):e1006128. doi: 10.1371/journal.ppat.1006128. eCollection 2017 Jan.

31.

A new Plasmodium vivax reference sequence with improved assembly of the subtelomeres reveals an abundance of pir genes.

Auburn S, Böhme U, Steinbiss S, Trimarsanto H, Hostetler J, Sanders M, Gao Q, Nosten F, Newbold CI, Berriman M, Price RN, Otto TD.

Wellcome Open Res. 2016 Nov 15;1:4. doi: 10.12688/wellcomeopenres.9876.1.

32.

Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification.

Oyola SO, Ariani CV, Hamilton WL, Kekre M, Amenga-Etego LN, Ghansah A, Rutledge GG, Redmond S, Manske M, Jyothi D, Jacob CG, Otto TD, Rockett K, Newbold CI, Berriman M, Kwiatkowski DP.

Malar J. 2016 Dec 20;15(1):597. doi: 10.1186/s12936-016-1641-7.

33.

Extreme mutation bias and high AT content in Plasmodium falciparum.

Hamilton WL, Claessens A, Otto TD, Kekre M, Fairhurst RM, Rayner JC, Kwiatkowski D.

Nucleic Acids Res. 2017 Feb 28;45(4):1889-1901. doi: 10.1093/nar/gkw1259.

34.

Correction: Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole.

Fougère A, Jackson AP, Paraskevi Bechtsi D, Braks JA, Annoura T, Fonager J, Spaccapelo R, Ramesar J, Chevalley-Maurel S, Klop O, van der Laan AM, Tanke HJ, Kocken CH, Pasini EM, Khan SM, Böhme U, van Ooij C, Otto TD, Janse CJ, Franke-Fayard B.

PLoS Pathog. 2016 Dec 14;12(12):e1006107. doi: 10.1371/journal.ppat.1006107. eCollection 2016 Dec.

35.

Last parasite standing.

Rutledge GG, Otto TD.

Nat Rev Microbiol. 2016 Dec 9;15(1):4. doi: 10.1038/nrmicro.2016.181.

PMID:
27932794
36.

Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole.

Fougère A, Jackson AP, Bechtsi DP, Braks JA, Annoura T, Fonager J, Spaccapelo R, Ramesar J, Chevalley-Maurel S, Klop O, van der Laan AM, Tanke HJ, Kocken CH, Pasini EM, Khan SM, Böhme U, van Ooij C, Otto TD, Janse CJ, Franke-Fayard B.

PLoS Pathog. 2016 Nov 16;12(11):e1005917. doi: 10.1371/journal.ppat.1005917. eCollection 2016 Nov. Erratum in: PLoS Pathog. 2016 Dec 14;12 (12 ):e1006107. PLoS Pathog. 2017 Jan 17;13(1):e1006128.

37.

Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host.

Klemm EJ, Gkrania-Klotsas E, Hadfield J, Forbester JL, Harris SR, Hale C, Heath JN, Wileman T, Clare S, Kane L, Goulding D, Otto TD, Kay S, Doffinger R, Cooke FJ, Carmichael A, Lever AM, Parkhill J, MacLennan CA, Kumararatne D, Dougan G, Kingsley RA.

Nat Microbiol. 2016 Jan 25;1:15023. doi: 10.1038/nmicrobiol.2015.23.

PMID:
27572160
38.

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis.

Baragaña B, Hallyburton I, Lee MC, Norcross NR, Grimaldi R, Otto TD, Proto WR, Blagborough AM, Meister S, Wirjanata G, Ruecker A, Upton LM, Abraham TS, Almeida MJ, Pradhan A, Porzelle A, Martínez MS, Bolscher JM, Woodland A, Luksch T, Norval S, Zuccotto F, Thomas J, Simeons F, Stojanovski L, Osuna-Cabello M, Brock PM, Churcher TS, Sala KA, Zakutansky SE, Jiménez-Díaz MB, Sanz LM, Riley J, Basak R, Campbell M, Avery VM, Sauerwein RW, Dechering KJ, Noviyanti R, Campo B, Frearson JA, Angulo-Barturen I, Ferrer-Bazaga S, Gamo FJ, Wyatt PG, Leroy D, Siegl P, Delves MJ, Kyle DE, Wittlin S, Marfurt J, Price RN, Sinden RE, Winzeler EA, Charman SA, Bebrevska L, Gray DW, Campbell S, Fairlamb AH, Willis PA, Rayner JC, Fidock DA, Read KD, Gilbert IH.

Nature. 2016 Sep 1;537(7618):122. doi: 10.1038/nature18280. Epub 2016 May 25. No abstract available.

39.

Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants.

Bronner IF, Otto TD, Zhang M, Udenze K, Wang C, Quail MA, Jiang RH, Adams JH, Rayner JC.

Genome Res. 2016 Jul;26(7):980-9. doi: 10.1101/gr.200279.115. Epub 2016 May 10.

40.

Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host.

Klemm EJ, Gkrania-Klotsas E, Hadfield J, Forbester JL, Harris SR, Hale C, Heath JN, Wileman T, Clare S, Kane L, Goulding D, Otto TD, Kay S, Doffinger R, Cooke FJ, Carmichael A, Lever AM, Parkhill J, MacLennan CA, Kumararatne D, Dougan G, Kingsley RA.

Nat Microbiol. 2016 Mar;1(3). pii: 15023. doi: 10.1038/nmicrobiol.2015.23. Epub 2016 Jan 25.

41.

Companion: a web server for annotation and analysis of parasite genomes.

Steinbiss S, Silva-Franco F, Brunk B, Foth B, Hertz-Fowler C, Berriman M, Otto TD.

Nucleic Acids Res. 2016 Jul 8;44(W1):W29-34. doi: 10.1093/nar/gkw292. Epub 2016 Apr 21.

42.

Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasites.

Ponsuwanna P, Kochakarn T, Bunditvorapoom D, Kümpornsin K, Otto TD, Ridenour C, Chotivanich K, Wilairat P, White NJ, Miotto O, Chookajorn T.

Malar J. 2016 Jan 29;15:51. doi: 10.1186/s12936-016-1097-9.

43.

Kinetoplastid Phylogenomics Reveals the Evolutionary Innovations Associated with the Origins of Parasitism.

Jackson AP, Otto TD, Aslett M, Armstrong SD, Bringaud F, Schlacht A, Hartley C, Sanders M, Wastling JM, Dacks JB, Acosta-Serrano A, Field MC, Ginger ML, Berriman M.

Curr Biol. 2016 Jan 25;26(2):161-172. doi: 10.1016/j.cub.2015.11.055. Epub 2015 Dec 24. Review.

44.

Circlator: automated circularization of genome assemblies using long sequencing reads.

Hunt M, Silva ND, Otto TD, Parkhill J, Keane JA, Harris SR.

Genome Biol. 2015 Dec 29;16:294. doi: 10.1186/s13059-015-0849-0.

45.

Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations.

Abdallah AM, Hill-Cawthorne GA, Otto TD, Coll F, Guerra-Assunção JA, Gao G, Naeem R, Ansari H, Malas TB, Adroub SA, Verboom T, Ummels R, Zhang H, Panigrahi AK, McNerney R, Brosch R, Clark TG, Behr MA, Bitter W, Pain A.

Sci Rep. 2015 Oct 21;5:15443. doi: 10.1038/srep15443.

46.

Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites.

Woo YH, Ansari H, Otto TD, Klinger CM, Kolisko M, Michálek J, Saxena A, Shanmugam D, Tayyrov A, Veluchamy A, Ali S, Bernal A, del Campo J, Cihlář J, Flegontov P, Gornik SG, Hajdušková E, Horák A, Janouškovec J, Katris NJ, Mast FD, Miranda-Saavedra D, Mourier T, Naeem R, Nair M, Panigrahi AK, Rawlings ND, Padron-Regalado E, Ramaprasad A, Samad N, Tomčala A, Wilkes J, Neafsey DE, Doerig C, Bowler C, Keeling PJ, Roos DS, Dacks JB, Templeton TJ, Waller RF, Lukeš J, Oborník M, Pain A.

Elife. 2015 Jul 15;4:e06974. doi: 10.7554/eLife.06974.

47.

A novel multiple-stage antimalarial agent that inhibits protein synthesis.

Baragaña B, Hallyburton I, Lee MC, Norcross NR, Grimaldi R, Otto TD, Proto WR, Blagborough AM, Meister S, Wirjanata G, Ruecker A, Upton LM, Abraham TS, Almeida MJ, Pradhan A, Porzelle A, Luksch T, Martínez MS, Luksch T, Bolscher JM, Woodland A, Norval S, Zuccotto F, Thomas J, Simeons F, Stojanovski L, Osuna-Cabello M, Brock PM, Churcher TS, Sala KA, Zakutansky SE, Jiménez-Díaz MB, Sanz LM, Riley J, Basak R, Campbell M, Avery VM, Sauerwein RW, Dechering KJ, Noviyanti R, Campo B, Frearson JA, Angulo-Barturen I, Ferrer-Bazaga S, Gamo FJ, Wyatt PG, Leroy D, Siegl P, Delves MJ, Kyle DE, Wittlin S, Marfurt J, Price RN, Sinden RE, Winzeler EA, Charman SA, Bebrevska L, Gray DW, Campbell S, Fairlamb AH, Willis PA, Rayner JC, Fidock DA, Read KD, Gilbert IH.

Nature. 2015 Jun 18;522(7556):315-20. doi: 10.1038/nature14451. Erratum in: Nature. 2016 Sep 1;537(7618):122.

48.

Comprehensive evaluation of Toxoplasma gondii VEG and Neospora caninum LIV genomes with tachyzoite stage transcriptome and proteome defines novel transcript features.

Ramaprasad A, Mourier T, Naeem R, Malas TB, Moussa E, Panigrahi A, Vermont SJ, Otto TD, Wastling J, Pain A.

PLoS One. 2015 Apr 13;10(4):e0124473. doi: 10.1371/journal.pone.0124473. eCollection 2015.

49.

Plasmodium knowlesi genome sequences from clinical isolates reveal extensive genomic dimorphism.

Pinheiro MM, Ahmed MA, Millar SB, Sanderson T, Otto TD, Lu WC, Krishna S, Rayner JC, Cox-Singh J.

PLoS One. 2015 Apr 1;10(4):e0121303. doi: 10.1371/journal.pone.0121303. eCollection 2015.

50.

IVA: accurate de novo assembly of RNA virus genomes.

Hunt M, Gall A, Ong SH, Brener J, Ferns B, Goulder P, Nastouli E, Keane JA, Kellam P, Otto TD.

Bioinformatics. 2015 Jul 15;31(14):2374-6. doi: 10.1093/bioinformatics/btv120. Epub 2015 Feb 28.

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