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Items: 18

1.

Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance.

Otto GW, Kaisaki PJ, Brial F, Le Lay A, Cazier JB, Mott R, Gauguier D.

Dis Model Mech. 2019 Jul 15;12(7). pii: dmm038539. doi: 10.1242/dmm.038539.

2.

Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment.

Brial F, Le Lay A, Hedjazi L, Tsang T, Fearnside JF, Otto GW, Alzaid F, Wilder SP, Venteclef N, Cazier JB, Nicholson JK, Day C, Burt AD, Gut IG, Lathrop M, Dumas ME, Gauguier D.

Sci Rep. 2019 Mar 6;9(1):3656. doi: 10.1038/s41598-019-40153-0.

3.

CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.

Piper CJM, Wilkinson MGL, Deakin CT, Otto GW, Dowle S, Duurland CL, Adams S, Marasco E, Rosser EC, Radziszewska A, Carsetti R, Ioannou Y, Beales PL, Kelberman D, Isenberg DA, Mauri C, Nistala K, Wedderburn LR.

Front Immunol. 2018 Jun 22;9:1372. doi: 10.3389/fimmu.2018.01372. eCollection 2018.

4.

Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series.

Dumas ME, Domange C, Calderari S, Martínez AR, Ayala R, Wilder SP, Suárez-Zamorano N, Collins SC, Wallis RH, Gu Q, Wang Y, Hue C, Otto GW, Argoud K, Navratil V, Mitchell SC, Lindon JC, Holmes E, Cazier JB, Nicholson JK, Gauguier D.

Genome Med. 2016 Sep 30;8(1):101.

5.

Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression.

Kaisaki PJ, Otto GW, Argoud K, Collins SC, Wallis RH, Wilder SP, Yau ACY, Hue C, Calderari S, Bihoreau MT, Cazier JB, Mott R, Gauguier D.

G3 (Bethesda). 2016 Nov 8;6(11):3671-3683. doi: 10.1534/g3.116.033274.

6.

Genetically distinct leukemic stem cells in human CD34- acute myeloid leukemia are arrested at a hemopoietic precursor-like stage.

Quek L, Otto GW, Garnett C, Lhermitte L, Karamitros D, Stoilova B, Lau IJ, Doondeea J, Usukhbayar B, Kennedy A, Metzner M, Goardon N, Ivey A, Allen C, Gale R, Davies B, Sternberg A, Killick S, Hunter H, Cahalin P, Price A, Carr A, Griffiths M, Virgo P, Mackinnon S, Grimwade D, Freeman S, Russell N, Craddock C, Mead A, Peniket A, Porcher C, Vyas P.

J Exp Med. 2016 Jul 25;213(8):1513-35. doi: 10.1084/jem.20151775. Epub 2016 Jul 4.

7.

Genetic control of differential acetylation in diabetic rats.

Kaisaki PJ, Otto GW, McGouran JF, Toubal A, Argoud K, Waller-Evans H, Finlay C, Caldérari S, Bihoreau MT, Kessler BM, Gauguier D, Mott R.

PLoS One. 2014 Apr 17;9(4):e94555. doi: 10.1371/journal.pone.0094555. eCollection 2014.

8.

A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain.

Dyer C, Blanc E, Hanisch A, Roehl H, Otto GW, Yu T, Basson MA, Knight R.

Development. 2014 Jan;141(1):63-72. doi: 10.1242/dev.099507. Epub 2013 Nov 27.

9.

Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat.

Atanur SS, Diaz AG, Maratou K, Sarkis A, Rotival M, Game L, Tschannen MR, Kaisaki PJ, Otto GW, Ma MC, Keane TM, Hummel O, Saar K, Chen W, Guryev V, Gopalakrishnan K, Garrett MR, Joe B, Citterio L, Bianchi G, McBride M, Dominiczak A, Adams DJ, Serikawa T, Flicek P, Cuppen E, Hubner N, Petretto E, Gauguier D, Kwitek A, Jacob H, Aitman TJ.

Cell. 2013 Aug 1;154(3):691-703. doi: 10.1016/j.cell.2013.06.040. Epub 2013 Jul 25.

10.

Causes and consequences of chromatin variation between inbred mice.

Hosseini M, Goodstadt L, Hughes JR, Kowalczyk MS, de Gobbi M, Otto GW, Copley RR, Mott R, Higgs DR, Flint J.

PLoS Genet. 2013 Jun;9(6):e1003570. doi: 10.1371/journal.pgen.1003570. Epub 2013 Jun 13.

11.

The light responsive transcriptome of the zebrafish: function and regulation.

Weger BD, Sahinbas M, Otto GW, Mracek P, Armant O, Dolle D, Lahiri K, Vallone D, Ettwiller L, Geisler R, Foulkes NS, Dickmeis T.

PLoS One. 2011 Feb 15;6(2):e17080. doi: 10.1371/journal.pone.0017080.

12.

Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis.

Choi J, Mouillesseaux K, Wang Z, Fiji HD, Kinderman SS, Otto GW, Geisler R, Kwon O, Chen JN.

Development. 2011 Mar;138(6):1173-81. doi: 10.1242/dev.054049. Epub 2011 Feb 9.

13.

Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration.

Kizil C, Otto GW, Geisler R, Nüsslein-Volhard C, Antos CL.

Dev Biol. 2009 Jan 15;325(2):329-40. doi: 10.1016/j.ydbio.2008.09.032. Epub 2008 Oct 17.

14.

Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae.

Voelker D, Vess C, Tillmann M, Nagel R, Otto GW, Geisler R, Schirmer K, Scholz S.

Aquat Toxicol. 2007 Mar 30;81(4):355-64. Epub 2007 Jan 12.

PMID:
17292976
15.

Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection.

Meijer AH, Verbeek FJ, Salas-Vidal E, Corredor-Adámez M, Bussman J, van der Sar AM, Otto GW, Geisler R, Spaink HP.

Mol Immunol. 2005 Jun;42(10):1185-203. Epub 2005 Jan 12.

PMID:
15829308
16.

AppaDB: an AcedB database for the nematode satellite organism Pristionchus pacificus.

Srinivasan J, Otto GW, Kahlow U, Geisler R, Sommer RJ.

Nucleic Acids Res. 2004 Jan 1;32(Database issue):D421-2.

17.

The integration site of the iga gene in commensal Neisseria sp.

Jose J, Otto GW, Meyer TF.

Mol Genet Genomics. 2003 May;269(2):197-204. Epub 2003 Apr 29.

PMID:
12720087
18.

Complex probes for high-throughput parallel genetic mapping of genomic mouse BAC clones.

Himmelbauer H, Dunkel I, Otto GW, Burgtorf C, Schalkwyk LC, Lehrach H.

Mamm Genome. 1998 Aug;9(8):611-6.

PMID:
9680379

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