Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 14

1.

Human Survival Motor Neuron genes generate a vast repertoire of circular RNAs.

Ottesen EW, Luo D, Seo J, Singh NN, Singh RN.

Nucleic Acids Res. 2019 Apr 8;47(6):2884-2905. doi: 10.1093/nar/gkz034.

2.

High-affinity RNA targets of the Survival Motor Neuron protein reveal diverse preferences for sequence and structural motifs.

Ottesen EW, Singh NN, Luo D, Singh RN.

Nucleic Acids Res. 2018 Nov 16;46(20):10983-11001. doi: 10.1093/nar/gky770.

3.

A Multilayered Control of the Human Survival Motor Neuron Gene Expression by Alu Elements.

Ottesen EW, Seo J, Singh NN, Singh RN.

Front Microbiol. 2017 Nov 15;8:2252. doi: 10.3389/fmicb.2017.02252. eCollection 2017. Review.

4.

Activation of a cryptic 5' splice site reverses the impact of pathogenic splice site mutations in the spinal muscular atrophy gene.

Singh NN, Del Rio-Malewski JB, Luo D, Ottesen EW, Howell MD, Singh RN.

Nucleic Acids Res. 2017 Dec 1;45(21):12214-12240. doi: 10.1093/nar/gkx824.

5.

TIA1 is a gender-specific disease modifier of a mild mouse model of spinal muscular atrophy.

Howell MD, Ottesen EW, Singh NN, Anderson RL, Seo J, Sivanesan S, Whitley EM, Singh RN.

Sci Rep. 2017 Aug 3;7(1):7183. doi: 10.1038/s41598-017-07468-2.

6.

Gender-Specific Amelioration of SMA Phenotype upon Disruption of a Deep Intronic Structure by an Oligonucleotide.

Howell MD, Ottesen EW, Singh NN, Anderson RL, Singh RN.

Mol Ther. 2017 Jun 7;25(6):1328-1341. doi: 10.1016/j.ymthe.2017.03.036. Epub 2017 Apr 13.

7.

ISS-N1 makes the First FDA-approved Drug for Spinal Muscular Atrophy.

Ottesen EW.

Transl Neurosci. 2017 Jan 26;8:1-6. doi: 10.1515/tnsci-2017-0001. eCollection 2017 Jan.

8.

Diverse role of survival motor neuron protein.

Singh RN, Howell MD, Ottesen EW, Singh NN.

Biochim Biophys Acta Gene Regul Mech. 2017 Mar;1860(3):299-315. doi: 10.1016/j.bbagrm.2016.12.008. Epub 2017 Jan 15. Review.

9.

A novel human-specific splice isoform alters the critical C-terminus of Survival Motor Neuron protein.

Seo J, Singh NN, Ottesen EW, Lee BM, Singh RN.

Sci Rep. 2016 Aug 2;6:30778. doi: 10.1038/srep30778.

10.

Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene.

Seo J, Singh NN, Ottesen EW, Sivanesan S, Shishimorova M, Singh RN.

PLoS One. 2016 Apr 25;11(4):e0154390. doi: 10.1371/journal.pone.0154390. eCollection 2016.

11.

Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy.

Ottesen EW, Howell MD, Singh NN, Seo J, Whitley EM, Singh RN.

Sci Rep. 2016 Feb 2;6:20193. doi: 10.1038/srep20193.

12.

Antisense methods to modulate pre-mRNA splicing.

Seo J, Ottesen EW, Singh RN.

Methods Mol Biol. 2014;1126:271-83. doi: 10.1007/978-1-62703-980-2_20.

PMID:
24549671
13.

An intronic structure enabled by a long-distance interaction serves as a novel target for splicing correction in spinal muscular atrophy.

Singh NN, Lawler MN, Ottesen EW, Upreti D, Kaczynski JR, Singh RN.

Nucleic Acids Res. 2013 Sep;41(17):8144-65. doi: 10.1093/nar/gkt609. Epub 2013 Jul 16.

14.

TIA1 prevents skipping of a critical exon associated with spinal muscular atrophy.

Singh NN, Seo J, Ottesen EW, Shishimorova M, Bhattacharya D, Singh RN.

Mol Cell Biol. 2011 Mar;31(5):935-54. doi: 10.1128/MCB.00945-10. Epub 2010 Dec 28.

Supplemental Content

Loading ...
Support Center