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Items: 35

1.

A protective role for the human SMG-1 kinase against tumor necrosis factor-alpha-induced apoptosis.

Oliveira V, Romanow WJ, Geisen C, Otterness DM, Mercurio F, Wang HG, Dalton WS, Abraham RT.

J Biol Chem. 2008 May 9;283(19):13174-84. doi: 10.1074/jbc.M708008200. Epub 2008 Mar 6.

2.

Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.

Zhang YW, Otterness DM, Chiang GG, Xie W, Liu YC, Mercurio F, Abraham RT.

Mol Cell. 2005 Sep 2;19(5):607-18.

3.

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells.

Brumbaugh KM, Otterness DM, Geisen C, Oliveira V, Brognard J, Li X, Lejeune F, Tibbetts RS, Maquat LE, Abraham RT.

Mol Cell. 2004 Jun 4;14(5):585-98.

4.

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

Hudson CC, Liu M, Chiang GG, Otterness DM, Loomis DC, Kaper F, Giaccia AJ, Abraham RT.

Mol Cell Biol. 2002 Oct;22(20):7004-14.

5.

Syntheses and biological activities of a novel group of steroidal derived inhibitors for human Cdc25A protein phosphatase.

Peng H, Xie W, Otterness DM, Cogswell JP, McConnell RT, Carter HL, Powis G, Abraham RT, Zalkow LH.

J Med Chem. 2001 Mar 1;44(5):834-48.

PMID:
11262093
6.

A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.

Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.

Cancer Res. 2000 Jul 1;60(13):3504-13.

7.

Steroidal derived acids as inhibitors of human Cdc25A protein phosphatase.

Peng H, Xie W, Kim DI, Zalkow LH, Powis G, Otterness DM, Abraham RT.

Bioorg Med Chem. 2000 Feb;8(2):299-306.

PMID:
10722152
8.

Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization.

Xu ZH, Otterness DM, Freimuth RR, Carlini EJ, Wood TC, Mitchell S, Moon E, Kim UJ, Xu JP, Siciliano MJ, Weinshilboum RM.

Biochem Biophys Res Commun. 2000 Feb 16;268(2):437-44.

PMID:
10679223
9.

Human nicotinamide N-methyltransferase pharmacogenetics: gene sequence analysis and promoter characterization.

Yan L, Otterness DM, Weinshilboum RM.

Pharmacogenetics. 1999 Jun;9(3):307-16.

PMID:
10471062
10.

Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase.

Weinshilboum RM, Otterness DM, Szumlanski CL.

Annu Rev Pharmacol Toxicol. 1999;39:19-52. Review.

PMID:
10331075
11.

Mouse nicotinamide N-methyltransferase gene: molecular cloning, structural characterization, and chromosomal localization.

Yan L, Otterness DM, Kozak CA, Weinshilboum RM.

DNA Cell Biol. 1998 Aug;17(8):659-67.

PMID:
9726248
12.

Human histamine N-methyltransferase pharmacogenetics: common genetic polymorphisms that alter activity.

Preuss CV, Wood TC, Szumlanski CL, Raftogianis RB, Otterness DM, Girard B, Scott MC, Weinshilboum RM.

Mol Pharmacol. 1998 Apr;53(4):708-17.

PMID:
9547362
13.
14.

Mouse liver nicotinamide N-methyltransferase: cDNA cloning, expression, and nucleotide sequence polymorphisms.

Yan L, Otterness DM, Craddock TL, Weinshilboum RM.

Biochem Pharmacol. 1997 Nov 15;54(10):1139-49.

PMID:
9464457
15.

Olsalazine and 6-mercaptopurine-related bone marrow suppression: a possible drug-drug interaction.

Lewis LD, Benin A, Szumlanski CL, Otterness DM, Lennard L, Weinshilboum RM, Nierenberg DW.

Clin Pharmacol Ther. 1997 Oct;62(4):464-75. Erratum in: Clin Pharmacol Ther 2000 Apr;67(4):431.

PMID:
9357398
16.

Phenol sulfotransferase pharmacogenetics in humans: association of common SULT1A1 alleles with TS PST phenotype.

Raftogianis RB, Wood TC, Otterness DM, Van Loon JA, Weinshilboum RM.

Biochem Biophys Res Commun. 1997 Oct 9;239(1):298-304.

PMID:
9345314
17.

Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes.

Weinshilboum RM, Otterness DM, Aksoy IA, Wood TC, Her C, Raftogianis RB.

FASEB J. 1997 Jan;11(1):3-14. Review.

PMID:
9034160
18.

Human dehydroepiandrosterone sulfotransferase pharmacogenetics: quantitative Western analysis and gene sequence polymorphisms.

Wood TC, Her C, Aksoy I, Otterness DM, Weinshilboum RM.

J Steroid Biochem Mol Biol. 1996 Dec;59(5-6):467-78.

PMID:
9010352
19.

Human dehydroepiandrosterone sulfotransferase gene: molecular cloning and structural characterization.

Otterness DM, Her C, Aksoy S, Kimura S, Wieben ED, Weinshilboum RM.

DNA Cell Biol. 1995 Apr;14(4):331-41.

PMID:
7710689
20.

Dehydroepiandrosterone sulfotransferase gene (STD): localization to human chromosome band 19q13.3.

Otterness DM, Mohrenweiser HW, Brandriff BF, Weinshilboum RM.

Cytogenet Cell Genet. 1995;70(1-2):45-7.

PMID:
7736787
21.

Purine substrates for human thiopurine methyltransferase.

Deininger M, Szumlanski CL, Otterness DM, Van Loon J, Ferber W, Weinshilboum RM.

Biochem Pharmacol. 1994 Nov 29;48(11):2135-8.

PMID:
7802704
22.

Human dehydroepiandrosterone sulfotransferase: molecular cloning of cDNA and genomic DNA.

Otterness DM, Weinshilboum R.

Chem Biol Interact. 1994 Jun;92(1-3):145-59. Review.

PMID:
8033249
23.

Human histamine N-methyltransferase pharmacogenetics: cloning and expression of kidney cDNA.

Girard B, Otterness DM, Wood TC, Honchel R, Wieben ED, Weinshilboum RM.

Mol Pharmacol. 1994 Mar;45(3):461-8.

PMID:
8145732
24.

Human thiopurine methyltransferase: molecular cloning and expression of T84 colon carcinoma cell cDNA.

Honchel R, Aksoy IA, Szumlanski C, Wood TC, Otterness DM, Wieben ED, Weinshilboum RM.

Mol Pharmacol. 1993 Jun;43(6):878-87.

PMID:
8316220
25.

Cholesterol sulfation in human liver. Catalysis by dehydroepiandrosterone sulfotransferase.

Aksoy IA, Otterness DM, Weinshilboum RM.

Drug Metab Dispos. 1993 Mar-Apr;21(2):268-76.

PMID:
8097696
26.

Human liver dehydroepiandrosterone sulfotransferase: molecular cloning and expression of cDNA.

Otterness DM, Wieben ED, Wood TC, Watson WG, Madden BJ, McCormick DJ, Weinshilboum RM.

Mol Pharmacol. 1992 May;41(5):865-72.

PMID:
1588921
27.

Thiopurine methyltransferase regulation in rat kidney: immunoprecipitation studies.

Hernández JS, Van Loon JA, Otterness DM, Guerciolini R, Weinshilboum RM.

Xenobiotica. 1991 Apr;21(4):451-9.

PMID:
1897245
28.

3'-Phosphoadenosine-5'-phosphosulfate: photoaffinity ligand for sulfotransferase enzymes.

Otterness DM, Powers SP, Miller LJ, Weinshilboum RM.

Mol Pharmacol. 1991 Jan;39(1):34-41.

PMID:
1987450
29.

Mouse thiopurine methyltransferase pharmacogenetics: correlation of immunoreactive protein and enzymatic activity.

Hernandez JS, Van Loon JA, Otterness DM, Weinshilboum RM.

J Pharmacol Exp Ther. 1990 Feb;252(2):568-73.

PMID:
2313588
30.

Human liver thermostable phenol sulfotransferase: photoaffinity labeling with 2-iodo-4-azidophenol.

Otterness DM, Powers SP, Miller LJ, Weinshilboum RM.

Mol Pharmacol. 1989 Dec;36(6):856-65.

PMID:
2601684
31.

Mouse thiopurine methyltransferase pharmacogenetics: biochemical studies and recombinant inbred strains.

Otterness DM, Weinshilboum RM.

J Pharmacol Exp Ther. 1987 Oct;243(1):180-6.

PMID:
3668849
32.

Mouse thiopurine methyltransferase pharmacogenetics: monogenic inheritance.

Otterness DM, Weinshilboum RM.

J Pharmacol Exp Ther. 1987 Mar;240(3):817-24.

PMID:
3559976
33.

Mouse liver thiol methyltransferase. Assay conditions, biochemical properties, and strain variation.

Otterness DM, Keith RA, Kerremans AL, Weinshilboum RM.

Drug Metab Dispos. 1986 Nov-Dec;14(6):680-8.

PMID:
2877826
34.

Thiopurine methyltransferase: mouse kidney and liver assay conditions, biochemical properties and strain variation.

Otterness DM, Keith RA, Weinshilboum RM.

Biochem Pharmacol. 1985 Nov 1;34(21):3823-30.

PMID:
4062957
35.

S-Methylation of D- and L-penicillamine by human erythrocyte membrane thiol methyltransferase.

Keith RA, Otterness DM, Kerremans AL, Weinshilboum RM.

Drug Metab Dispos. 1985 Nov-Dec;13(6):669-76.

PMID:
2867869

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