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Items: 1 to 50 of 297

1.

Identification of Two DNMT3A Mutations Compromising Protein Stability and Methylation Capacity in Acute Myeloid Leukemia.

Bruno S, Bochicchio MT, Franchini E, Padella A, Marconi G, Ghelli Luserna di Rorà A, Venturi C, Raffini M, Prisinzano G, Ferrari A, Bandini L, Robustelli V, Pazzaglia M, Fontana MC, Sartor C, Abbenante MC, Papayannidis C, Soverini S, Ottaviani E, Simonetti G, Martinelli G.

J Oncol. 2019 Oct 30;2019:5985923. doi: 10.1155/2019/5985923. eCollection 2019.

2.

Novel and Rare Fusion Transcripts Involving Transcription Factors and Tumor Suppressor Genes in Acute Myeloid Leukemia.

Padella A, Simonetti G, Paciello G, Giotopoulos G, Baldazzi C, Righi S, Ghetti M, Stengel A, Guadagnuolo V, De Tommaso R, Papayannidis C, Robustelli V, Franchini E, Rorà AGLD, Ferrari A, Fontana MC, Bruno S, Ottaviani E, Soverini S, Storlazzi CT, Haferlach C, Sabattini E, Testoni N, Iacobucci I, Huntly BJP, Ficarra E, Martinelli G.

Cancers (Basel). 2019 Dec 5;11(12). pii: E1951. doi: 10.3390/cancers11121951.

3.

Concurrent chromothripsis events in a case of TP53 depleted acute myeloid leukemia with myelodysplasia-related changes.

Tolomeo D, L'Abbate A, Lonoce A, D'Addabbo P, Miccoli MF, Lo Cunsolo C, Iuzzolino P, Palumbo O, Carella M, Racanelli V, Mazza T, Ottaviani E, Martinelli G, Macchia G, Storlazzi CT.

Cancer Genet. 2019 Sep;237:63-68. doi: 10.1016/j.cancergen.2019.06.009. Epub 2019 Jun 12.

PMID:
31447067
4.

Impact of Gut Microbiota Composition on Onset and Progression of Chronic Non-Communicable Diseases.

Noce A, Marrone G, Di Daniele F, Ottaviani E, Wilson Jones G, Bernini R, Romani A, Rovella V.

Nutrients. 2019 May 14;11(5). pii: E1073. doi: 10.3390/nu11051073. Review.

5.

Exploiting the interplay between cross-sectional and longitudinal data in Class III malocclusion patients.

Barelli E, Ottaviani E, Auconi P, Caldarelli G, Giuntini V, McNamara JA Jr, Franchi L.

Sci Rep. 2019 Apr 17;9(1):6189. doi: 10.1038/s41598-019-42384-7.

6.

Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery.

Simonetti G, Padella A, do Valle IF, Fontana MC, Fonzi E, Bruno S, Baldazzi C, Guadagnuolo V, Manfrini M, Ferrari A, Paolini S, Papayannidis C, Marconi G, Franchini E, Zuffa E, Laginestra MA, Zanotti F, Astolfi A, Iacobucci I, Bernardi S, Sazzini M, Ficarra E, Hernandez JM, Vandenberghe P, Cools J, Bullinger L, Ottaviani E, Testoni N, Cavo M, Haferlach T, Castellani G, Remondini D, Martinelli G.

Cancer. 2019 Mar 1;125(5):712-725. doi: 10.1002/cncr.31837. Epub 2018 Nov 27.

7.

Circulating megakaryocyte and platelet microvesicles correlate with response to ruxolitinib and distinct disease severity in patients with myelofibrosis.

Barone M, Ricci F, Sollazzo D, Ottaviani E, Romano M, Auteri G, Bartoletti D, Reggiani MLB, Vianelli N, Tazzari PL, Cavo M, Forte D, Palandri F, Catani L.

Br J Haematol. 2019 Jun;185(5):987-991. doi: 10.1111/bjh.15682. Epub 2018 Nov 18. No abstract available.

PMID:
30450539
8.

Chromothripsis in acute myeloid leukemia: biological features and impact on survival.

Fontana MC, Marconi G, Feenstra JDM, Fonzi E, Papayannidis C, Ghelli Luserna di Rorá A, Padella A, Solli V, Franchini E, Ottaviani E, Ferrari A, Baldazzi C, Testoni N, Iacobucci I, Soverini S, Haferlach T, Guadagnuolo V, Semerad L, Doubek M, Steurer M, Racil Z, Paolini S, Manfrini M, Cavo M, Simonetti G, Kralovics R, Martinelli G.

Leukemia. 2018 Jul;32(7):1609-1620. doi: 10.1038/s41375-018-0035-y. Epub 2018 Feb 23.

9.

Chromothripsis in acute myeloid leukemia: Biological features and impact on survival.

Fontana MC, Marconi G, Feenstra JDM, Fonzi E, Papayannidis C, di Rorá AGL, Padella A, Solli V, Franchini E, Ottaviani E, Ferrari A, Baldazzi C, Testoni N, Iacobucci I, Soverini S, Haferlach T, Guadagnuolo V, Semerad L, Doubek M, Steurer M, Racil Z, Paolini S, Manfrini M, Cavo M, Simonetti G, Kralovics R, Martinelli G.

Leukemia. 2017 Dec 18. doi: 10.1038/leu.2017.351. [Epub ahead of print]

10.

Immune-Neuroendocrine Interactions: Evolution, Ecology, and Susceptibility to Illness.

Blom JMC, Ottaviani E.

Med Sci Monit Basic Res. 2017 Nov 16;23:362-367. Review.

11.

A new cellular type in invertebrates: first evidence of telocytes in leech Hirudo medicinalis.

Pulze L, Baranzini N, Girardello R, Grimaldi A, Ibba-Manneschi L, Ottaviani E, Reguzzoni M, Tettamanti G, de Eguileor M.

Sci Rep. 2017 Oct 19;7(1):13580. doi: 10.1038/s41598-017-13202-9.

12.

Multiple linear regression and artificial neural networks for delta-endotoxin and protease yields modelling of Bacillus thuringiensis.

Ennouri K, Ben Ayed R, Triki MA, Ottaviani E, Mazzarello M, Hertelli F, Zouari N.

3 Biotech. 2017 Jul;7(3):187. doi: 10.1007/s13205-017-0799-1. Epub 2017 Jun 29.

13.

Comparison of JAK2V617F -positive essential thrombocythaemia and early primary myelofibrosis: The impact of mutation burden and histology.

Latagliata R, Polverelli N, Tieghi A, Palumbo GA, Breccia M, Sabattini E, Villari L, Riminucci M, Valli R, Catani L, Alimena G, Ottaviani E, Fama A, Martinelli G, Perricone M, Spinsanti M, Cavo M, Vianelli N, Palandri F.

Hematol Oncol. 2018 Feb;36(1):269-275. doi: 10.1002/hon.2430. Epub 2017 May 16.

PMID:
28509339
14.

Assessment of the interlaboratory variability and robustness of JAK2V617F mutation assays: A study involving a consortium of 19 Italian laboratories.

Perricone M, Palandri F, Ottaviani E, Angelini M, Bagli L, Bellesia E, Donati M, Gemmati D, Zucchini P, Mancini S, Marchica V, Trubini S, De Matteis G, Di Zacomo S, Favarato M, Fioroni A, Bolzonella C, Maccari G, Navaglia F, Gatti D, Toffolatti L, Orlandi L, Laloux V, Manfrini M, Galieni P, Giannini B, Tieghi A, Barulli S, Serino ML, Maccaferri M, Scortechini AR, Giuliani N, Vallisa D, Bonifacio M, Accorsi P, Salbe C, Fazio V, Gusella M, Toffoletti E, Salvucci M, Svaldi M, Gherlinzoni F, Cassavia F, Orsini F, Martinelli G.

Oncotarget. 2017 May 16;8(20):32608-32617. doi: 10.18632/oncotarget.15940.

15.

The relevance of a low JAK2V617F allele burden in clinical practice: a monocentric study.

Perricone M, Polverelli N, Martinelli G, Catani L, Ottaviani E, Zuffa E, Franchini E, Dizdari A, Forte D, Sabattini E, Cavo M, Vianelli N, Palandri F.

Oncotarget. 2017 Jun 6;8(23):37239-37249. doi: 10.18632/oncotarget.16744.

16.

Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells.

Daniele G, Simonetti G, Fusilli C, Iacobucci I, Lonoce A, Palazzo A, Lomiento M, Mammoli F, Marsano RM, Marasco E, Mantovani V, Quentmeier H, Drexler HG, Ding J, Palumbo O, Carella M, Nadarajah N, Perricone M, Ottaviani E, Baldazzi C, Testoni N, Papayannidis C, Ferrari S, Mazza T, Martinelli G, Storlazzi CT.

Haematologica. 2017 Jul;102(7):1204-1214. doi: 10.3324/haematol.2016.163022. Epub 2017 Apr 14.

17.

A novel application of an adaptable modeling approach to the management of toxic microalgal bloom events in coastal areas.

Asnaghi V, Pecorino D, Ottaviani E, Pedroncini A, Bertolotto RM, Chiantore M.

Harmful Algae. 2017 Mar;63:184-192. doi: 10.1016/j.hal.2017.02.003. Epub 2017 Mar 10.

PMID:
28366393
18.

Thymus: Conservation in evolution.

Franchini A, Ottaviani E.

Gen Comp Endocrinol. 2017 May 15;246:46-50. doi: 10.1016/j.ygcen.2017.03.011. Epub 2017 Mar 18. Review.

PMID:
28322763
19.

Cross-talk among immune and neuroendocrine systems in molluscs and other invertebrate models.

Malagoli D, Ottaviani E.

Horm Behav. 2017 Feb;88:41-44. doi: 10.1016/j.yhbeh.2016.10.015. Epub 2016 Oct 28. Review.

PMID:
27984033
20.

Looking inside the Ocean: Toward an Autonomous Imaging System for Monitoring Gelatinous Zooplankton.

Corgnati L, Marini S, Mazzei L, Ottaviani E, Aliani S, Conversi A, Griffa A.

Sensors (Basel). 2016 Dec 14;16(12). pii: E2124.

21.

Efficacy of Azacitidine in the treatment of adult patients aged 65 years or older with AML.

Tenti E, Papayannidis C, Marconi G, Parisi S, Simonetti G, Paolini S, Sartor C, Ottaviani E, Testoni N, Martinelli G.

Expert Opin Pharmacother. 2016 Dec;17(18):2479-2486. Epub 2016 Nov 21. Review.

PMID:
27829292
22.

Crucial factors of the inflammatory microenvironment (IL-1β/TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study.

Sollazzo D, Forte D, Polverelli N, Romano M, Perricone M, Rossi L, Ottaviani E, Luatti S, Martinelli G, Vianelli N, Cavo M, Palandri F, Catani L.

Oncotarget. 2016 Jul 12;7(28):43974-43988. doi: 10.18632/oncotarget.9949.

23.

Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: a new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients.

Trino S, Iacobucci I, Erriquez D, Laurenzana I, De Luca L, Ferrari A, Ghelli Luserna Di Rorà A, Papayannidis C, Derenzini E, Simonetti G, Lonetti A, Venturi C, Cattina F, Ottaviani E, Abbenante MC, Russo D, Perini G, Musto P, Martinelli G.

Oncotarget. 2016 Mar 15;7(11):12951-61. doi: 10.18632/oncotarget.7339.

24.

Complex chromosomal rearrangements leading to MECOM overexpression are recurrent in myeloid malignancies with various 3q abnormalities.

Baldazzi C, Luatti S, Zuffa E, Papayannidis C, Ottaviani E, Marzocchi G, Ameli G, Bardi MA, Bonaldi L, Paolini R, Gurrieri C, Rigolin GM, Cuneo A, Martinelli G, Cavo M, Testoni N.

Genes Chromosomes Cancer. 2016 Apr;55(4):375-88. doi: 10.1002/gcc.22341. Epub 2016 Jan 27.

PMID:
26815134
25.

Classical and Bayesian predictions applied to Bacillus toxin production.

Ennouri K, Ben Ayed R, Mazzarello M, Ottaviani E, Hertelli F, Azzouz H.

3 Biotech. 2016 Dec;6(2):206. doi: 10.1007/s13205-016-0527-2. Epub 2016 Sep 26.

26.

Experimental design and Bayesian networks for enhancement of delta-endotoxin production by Bacillus thuringiensis.

Ennouri K, Ayed RB, Hassen HB, Mazzarello M, Ottaviani E.

Acta Microbiol Immunol Hung. 2015 Dec;62(4):379-92. doi: 10.1556/030.62.2015.4.3.

PMID:
26689874
27.

Circulating phagocytes: the ancient and conserved interface between immune and neuroendocrine function.

Malagoli D, Mandrioli M, Tascedda F, Ottaviani E.

Biol Rev Camb Philos Soc. 2017 Feb;92(1):369-377. doi: 10.1111/brv.12234. Epub 2015 Nov 9.

PMID:
26548761
28.

In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia.

Iacobucci I, Di Rorà AG, Falzacappa MV, Agostinelli C, Derenzini E, Ferrari A, Papayannidis C, Lonetti A, Righi S, Imbrogno E, Pomella S, Venturi C, Guadagnuolo V, Cattina F, Ottaviani E, Abbenante MC, Vitale A, Elia L, Russo D, Zinzani PL, Pileri S, Pelicci PG, Martinelli G.

J Hematol Oncol. 2015 Nov 5;8:125. doi: 10.1186/s13045-015-0206-5.

29.

Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients.

Zuffa E, Franchini E, Papayannidis C, Baldazzi C, Simonetti G, Testoni N, Abbenante MC, Paolini S, Sartor C, Parisi S, Marconi G, Cattina F, Bochicchio MT, Venturi C, Ottaviani E, Cavo M, Martinelli G.

Oncotarget. 2015 Oct 13;6(31):31284-94. doi: 10.18632/oncotarget.5161.

30.

Molluscs as models for translational medicine.

Tascedda F, Malagoli D, Accorsi A, Rigillo G, Blom JM, Ottaviani E.

Med Sci Monit Basic Res. 2015 Apr 30;21:96-9. doi: 10.12659/MSMBR.894221.

31.

Long-term efficacy and safety of nilotinib therapy after imatinib failure in eosinophilic myeloproliferative neoplasm and ETV6-ABL rearrangement.

Tiribelli M, Barraco D, Medeot M, Marin L, Ottaviani E, De Marchi F, Damiani D, Fanin R.

Ann Hematol. 2015 Aug;94(8):1423-4. doi: 10.1007/s00277-015-2381-4. Epub 2015 Apr 23. No abstract available.

PMID:
25900790
32.

NPM1 mutations may reveal acute myeloid leukemia in cases otherwise morphologically diagnosed as myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms.

Forghieri F, Paolini A, Morselli M, Bigliardi S, Bonacorsi G, Leonardi G, Coluccio V, Maccaferri M, Fantuzzi V, Faglioni L, Colaci E, Soci F, Nasillo V, Messerotti A, Arletti L, Pioli V, Zucchini P, Quadrelli C, Corradini G, Giacobbi F, Vallerini D, Riva G, Barozzi P, Lagreca I, Marasca R, Narni F, Mecucci C, Ottaviani E, Martinelli G, Falini B, Luppi M, Potenza L.

Leuk Lymphoma. 2015;56(11):3222-6. doi: 10.3109/10428194.2015.1026900. Epub 2015 May 12. Review. No abstract available.

PMID:
25813079
33.

Mutations and long-term outcome of 217 young patients with essential thrombocythemia or early primary myelofibrosis.

Palandri F, Latagliata R, Polverelli N, Tieghi A, Crugnola M, Martino B, Perricone M, Breccia M, Ottaviani E, Testoni N, Merli F, Aversa F, Alimena G, Cavo M, Martinelli G, Catani L, Baccarani M, Vianelli N.

Leukemia. 2015 Jun;29(6):1344-9. doi: 10.1038/leu.2015.87. Epub 2015 Mar 24.

PMID:
25801912
34.

Quantifiler® Trio Kit and forensic samples management: a matter of degradation.

Vernarecci S, Ottaviani E, Agostino A, Mei E, Calandro L, Montagna P.

Forensic Sci Int Genet. 2015 May;16:77-85. doi: 10.1016/j.fsigen.2014.12.005. Epub 2014 Dec 24.

PMID:
25544252
35.

Preliminary assessment of the prototype Yfiler® Plus kit in a population study of Northern Italian males.

Ottaviani E, Vernarecci S, Asili P, Agostino A, Montagna P.

Int J Legal Med. 2015 Jul;129(4):729-30. doi: 10.1007/s00414-014-1078-x. Epub 2014 Sep 6.

PMID:
25193819
36.

[Molecular biology in myelodysplastic syndromes and acute myeloid leukemias "smoldering"].

Martinelli G, Sartor C, Papayannidis C, Iacobucci I, Paolini S, Clissa C, Ottaviani E, Finelli C.

Recenti Prog Med. 2014 Mar;105(3):118-22. doi: 10.1701/1434.15873. Italian.

PMID:
24675454
37.

Effects of repeated hemolymph withdrawals on the hemocyte populations and hematopoiesis in Pomacea canaliculata.

Accorsi A, Ottaviani E, Malagoli D.

Fish Shellfish Immunol. 2014 May;38(1):56-64. doi: 10.1016/j.fsi.2014.03.003. Epub 2014 Mar 15.

PMID:
24636857
38.

Use of a high sensitive nanofluidic array for the detection of rare copies of BCR-ABL1 transcript in patients with Philadelphia-positive acute lymphoblastic leukemia in complete response.

Iacobucci I, Lonetti A, Venturi C, Ferrari A, Papayannidis C, Ottaviani E, Abbenante MC, Paolini S, Bresciani P, Potenza L, Parisi S, Cattina F, Soverini S, Russo D, Luppi M, Martinelli G.

Leuk Res. 2014 May;38(5):581-5. doi: 10.1016/j.leukres.2014.02.005. Epub 2014 Feb 18.

PMID:
24630366
39.

Epigenetic modification in neurons of the mollusc Pomacea canaliculata after immune challenge.

Ottaviani E, Accorsi A, Rigillo G, Malagoli D, Blom JM, Tascedda F.

Brain Res. 2013 Nov 6;1537:18-26. doi: 10.1016/j.brainres.2013.09.009. Epub 2013 Sep 13.

PMID:
24041774
40.

A case report of acute myeloid leukemia and neurofibromatosis 1.

Sartor C, Papayannidis C, Chiara Abbenante M, Curti A, Polverelli N, Ottaviani E, Iacobucci I, Guadagnuolo V, Martinelli G.

Hematol Rep. 2013 Jul 3;5(2):28-9. doi: 10.4081/hr.2013.e8. Print 2013 Jun 28.

41.

Comparative analysis of circulating hemocytes of the freshwater snail Pomacea canaliculata.

Accorsi A, Bucci L, de Eguileor M, Ottaviani E, Malagoli D.

Fish Shellfish Immunol. 2013 May;34(5):1260-8. doi: 10.1016/j.fsi.2013.02.008. Epub 2013 Feb 16.

PMID:
23422816
42.

The main actors involved in parasitization of Heliothis virescens larva.

Grimaldi A, Tettamanti G, Congiu T, Girardello R, Malagoli D, Falabella P, Valvassori R, Ottaviani E, de Eguileor M.

Cell Tissue Res. 2012 Dec;350(3):491-502. doi: 10.1007/s00441-012-1503-8. Epub 2012 Oct 6.

PMID:
23053052
43.

IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia.

Iacobucci I, Iraci N, Messina M, Lonetti A, Chiaretti S, Valli E, Ferrari A, Papayannidis C, Paoloni F, Vitale A, Storlazzi CT, Ottaviani E, Guadagnuolo V, Durante S, Vignetti M, Soverini S, Pane F, Foà R, Baccarani M, Müschen M, Perini G, Martinelli G.

PLoS One. 2012;7(7):e40934. doi: 10.1371/journal.pone.0040934. Epub 2012 Jul 25.

44.

Profiling of drug-metabolizing enzymes/transporters in CD33+ acute myeloid leukemia patients treated with Gemtuzumab-Ozogamicin and Fludarabine, Cytarabine and Idarubicin.

Iacobucci I, Lonetti A, Candoni A, Sazzini M, Papayannidis C, Formica S, Ottaviani E, Ferrari A, Michelutti A, Simeone E, Astolfi A, Abbenante MC, Parisi S, Cattina F, Malagola M, Russo D, Damiani D, Gherlinzoni F, Gottardi M, Baccarani M, Fanin R, Martinelli G.

Pharmacogenomics J. 2013 Aug;13(4):335-41. doi: 10.1038/tpj.2012.13. Epub 2012 May 15.

PMID:
22584460
45.

Drosophila Helical factor is an inducible protein acting as an immune-regulated cytokine in S2 cells.

Malagoli D, Accorsi A, Sacchi S, Basile V, Mandrioli M, Pinti M, Conklin D, Ottaviani E.

Cytokine. 2012 May;58(2):280-6. doi: 10.1016/j.cyto.2012.02.002. Epub 2012 Mar 2.

PMID:
22386007
46.

Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains.

Franchini A, Mandrioli M, Franceschi C, Ottaviani E.

J Mol Histol. 2012 Apr;43(2):243-51. doi: 10.1007/s10735-011-9382-y. Epub 2011 Dec 17.

PMID:
22179854
47.

CDKN2A/B alterations impair prognosis in adult BCR-ABL1-positive acute lymphoblastic leukemia patients.

Iacobucci I, Ferrari A, Lonetti A, Papayannidis C, Paoloni F, Trino S, Storlazzi CT, Ottaviani E, Cattina F, Impera L, Abbenante MC, Vignetti M, Vitale A, Potenza L, Paolini S, Soverini S, Pane F, Luppi M, Foà R, Baccarani M, Martinelli G.

Clin Cancer Res. 2011 Dec 1;17(23):7413-23. doi: 10.1158/1078-0432.CCR-11-1227.

48.

Very elderly patients with essential thrombocythaemia: are they a separate category? A monocentric study on 118 patients older than 75 years.

Palandri F, Polverelli N, Catani L, Ottaviani E, Baccarani M, Vianelli N.

Br J Haematol. 2012 Mar;156(5):676-9. doi: 10.1111/j.1365-2141.2011.08903.x. Epub 2011 Oct 8. No abstract available.

PMID:
21981043
49.

The evolution of pro-opiomelanocortin: looking for the invertebrate fingerprints.

Malagoli D, Accorsi A, Ottaviani E.

Peptides. 2011 Oct;32(10):2137-40. doi: 10.1016/j.peptides.2011.09.008. Epub 2011 Sep 14. Review.

PMID:
21939704
50.

Bleeding in essential thrombocythaemia: a retrospective analysis on 565 patients.

Palandri F, Polverelli N, Catani L, Sollazzo D, Ottaviani E, Parisi S, Baccarani M, Vianelli N.

Br J Haematol. 2012 Jan;156(2):281-4. doi: 10.1111/j.1365-2141.2011.08858.x. Epub 2011 Sep 21. No abstract available.

PMID:
21936859

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