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Items: 1 to 50 of 57

1.

Cortical column and whole-brain imaging with molecular contrast and nanoscale resolution.

Gao R, Asano SM, Upadhyayula S, Pisarev I, Milkie DE, Liu TL, Singh V, Graves A, Huynh GH, Zhao Y, Bogovic J, Colonell J, Ott CM, Zugates C, Tappan S, Rodriguez A, Mosaliganti KR, Sheu SH, Pasolli HA, Pang S, Xu CS, Megason SG, Hess H, Lippincott-Schwartz J, Hantman A, Rubin GM, Kirchhausen T, Saalfeld S, Aso Y, Boyden ES, Betzig E.

Science. 2019 Jan 18;363(6424). pii: eaau8302. doi: 10.1126/science.aau8302.

PMID:
30655415
2.

Evaluation of Acquired Antibiotic Resistance in Escherichia coli Exposed to Long-Term Low-Shear Modeled Microgravity and Background Antibiotic Exposure.

Tirumalai MR, Karouia F, Tran Q, Stepanov VG, Bruce RJ, Ott CM, Pierson DL, Fox GE.

MBio. 2019 Jan 15;10(1). pii: e02637-18. doi: 10.1128/mBio.02637-18.

3.

Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of Age.

Barrila J, Crabbé A, Yang J, Franco K, Nydam SD, Forsyth RJ, Davis RR, Gangaraju S, Ott CM, Coyne CB, Bissell MJ, Nickerson CA.

Infect Immun. 2018 Oct 25;86(11). pii: e00282-18. doi: 10.1128/IAI.00282-18. Print 2018 Nov. Review.

4.

Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions.

Crucian BE, Choukèr A, Simpson RJ, Mehta S, Marshall G, Smith SM, Zwart SR, Heer M, Ponomarev S, Whitmire A, Frippiat JP, Douglas GL, Lorenzi H, Buchheim JI, Makedonas G, Ginsburg GS, Ott CM, Pierson DL, Krieger SS, Baecker N, Sams C.

Front Immunol. 2018 Jun 28;9:1437. doi: 10.3389/fimmu.2018.01437. eCollection 2018. Review.

5.

Spaceflight modulates gene expression in the whole blood of astronauts.

Barrila J, Ott CM, LeBlanc C, Mehta SK, Crabbé A, Stafford P, Pierson DL, Nickerson CA.

NPJ Microgravity. 2016 Dec 8;2:16039. doi: 10.1038/npjmgrav.2016.39. eCollection 2016.

6.

Physiological fluid shear alters the virulence potential of invasive multidrug-resistant non-typhoidal Salmonella Typhimurium D23580.

Yang J, Barrila J, Roland KL, Ott CM, Nickerson CA.

NPJ Microgravity. 2016 Jun 9;2:16021. doi: 10.1038/npjmgrav.2016.21. eCollection 2016.

7.

The adaptation of Escherichia coli cells grown in simulated microgravity for an extended period is both phenotypic and genomic.

Tirumalai MR, Karouia F, Tran Q, Stepanov VG, Bruce RJ, Ott CM, Pierson DL, Fox GE.

NPJ Microgravity. 2017 May 23;3:15. doi: 10.1038/s41526-017-0020-1. eCollection 2017.

8.

Three-dimensional organotypic co-culture model of intestinal epithelial cells and macrophages to study Salmonella enterica colonization patterns.

Barrila J, Yang J, Crabbé A, Sarker SF, Liu Y, Ott CM, Nelman-Gonzalez MA, Clemett SJ, Nydam SD, Forsyth RJ, Davis RR, Crucian BE, Quiriarte H, Roland KL, Brenneman K, Sams C, Loscher C, Nickerson CA.

NPJ Microgravity. 2017 Feb 28;3:10. doi: 10.1038/s41526-017-0011-2. eCollection 2017.

9.

Incidence of clinical symptoms during long-duration orbital spaceflight.

Crucian B, Babiak-Vazquez A, Johnston S, Pierson DL, Ott CM, Sams C.

Int J Gen Med. 2016 Nov 3;9:383-391. eCollection 2016.

10.

Midbody remnant licenses primary cilia formation in epithelial cells.

Ott CM.

J Cell Biol. 2016 Aug 1;214(3):237-9. doi: 10.1083/jcb.201607046.

11.

Characterization of the Invasive, Multidrug Resistant Non-typhoidal Salmonella Strain D23580 in a Murine Model of Infection.

Yang J, Barrila J, Roland KL, Kilbourne J, Ott CM, Forsyth RJ, Nickerson CA.

PLoS Negl Trop Dis. 2015 Jun 19;9(6):e0003839. doi: 10.1371/journal.pntd.0003839. eCollection 2015 Jun.

12.

Intracellular and extracellular forces drive primary cilia movement.

Battle C, Ott CM, Burnette DT, Lippincott-Schwartz J, Schmidt CF.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1410-5. doi: 10.1073/pnas.1421845112. Epub 2015 Jan 20.

13.

Draft Genome Sequences of Ralstonia pickettii Strains SSH4 and CW2, Isolated from Space Equipment.

Monsieurs P, Mijnendonckx K, Provoost A, Venkateswaran K, Ott CM, Leys N, Van Houdt R.

Genome Announc. 2014 Sep 4;2(5). pii: e00887-14. doi: 10.1128/genomeA.00887-14.

14.

Genome Sequences of Cupriavidus metallidurans Strains NA1, NA4, and NE12, Isolated from Space Equipment.

Monsieurs P, Mijnendonckx K, Provoost A, Venkateswaran K, Ott CM, Leys N, Van Houdt R.

Genome Announc. 2014 Jul 24;2(4). pii: e00719-14. doi: 10.1128/genomeA.00719-14.

15.

Conservation of the Low-shear Modeled Microgravity Response in Enterobacteriaceae and Analysis of the trp Genes in this Response.

Soni A, O'Sullivan L, Quick LN, Ott CM, Nickerson CA, Wilson JW.

Open Microbiol J. 2014 Jun 13;8:51-8. doi: 10.2174/1874285801408010051. eCollection 2014.

16.

Spaceflight enhances cell aggregation and random budding in Candida albicans.

Crabbé A, Nielsen-Preiss SM, Woolley CM, Barrila J, Buchanan K, McCracken J, Inglis DO, Searles SC, Nelman-Gonzalez MA, Ott CM, Wilson JW, Pierson DL, Stefanyshyn-Piper HM, Hyman LE, Nickerson CA.

PLoS One. 2013 Dec 4;8(12):e80677. doi: 10.1371/journal.pone.0080677. eCollection 2013.

17.

Characterization of the survival ability of Cupriavidus metallidurans and Ralstonia pickettii from space-related environments.

Mijnendonckx K, Provoost A, Ott CM, Venkateswaran K, Mahillon J, Leys N, Van Houdt R.

Microb Ecol. 2013 Feb;65(2):347-60. doi: 10.1007/s00248-012-0139-2. Epub 2012 Dec 5.

PMID:
23212653
18.

Reactivation of latent viruses is associated with increased plasma cytokines in astronauts.

Mehta SK, Crucian BE, Stowe RP, Simpson RJ, Ott CM, Sams CF, Pierson DL.

Cytokine. 2013 Jan;61(1):205-9. doi: 10.1016/j.cyto.2012.09.019. Epub 2012 Oct 26.

PMID:
23107825
19.

Evaluation of microorganisms cultured from injured and repressed tissue regeneration sites in endangered giant aquatic Ozark Hellbender salamanders.

Nickerson CA, Ott CM, Castro SL, Garcia VM, Molina TC, Briggler JT, Pitt AL, Tavano JJ, Byram JK, Barrila J, Nickerson MA.

PLoS One. 2011;6(12):e28906. doi: 10.1371/journal.pone.0028906. Epub 2011 Dec 19.

20.

Induction of attachment-independent biofilm formation and repression of Hfq expression by low-fluid-shear culture of Staphylococcus aureus.

Castro SL, Nelman-Gonzalez M, Nickerson CA, Ott CM.

Appl Environ Microbiol. 2011 Sep;77(18):6368-78. doi: 10.1128/AEM.00175-11. Epub 2011 Jul 29.

21.

Characterization of the Salmonella enterica serovar Typhimurium ydcI gene, which encodes a conserved DNA binding protein required for full acid stress resistance.

Jennings ME, Quick LN, Soni A, Davis RR, Crosby K, Ott CM, Nickerson CA, Wilson JW.

J Bacteriol. 2011 May;193(9):2208-17. doi: 10.1128/JB.01335-10. Epub 2011 Mar 11.

22.

Transcriptional and proteomic responses of Pseudomonas aeruginosa PAO1 to spaceflight conditions involve Hfq regulation and reveal a role for oxygen.

Crabbé A, Schurr MJ, Monsieurs P, Morici L, Schurr J, Wilson JW, Ott CM, Tsaprailis G, Pierson DL, Stefanyshyn-Piper H, Nickerson CA.

Appl Environ Microbiol. 2011 Feb;77(4):1221-30. doi: 10.1128/AEM.01582-10. Epub 2010 Dec 17.

23.

Alveolar epithelium protects macrophages from quorum sensing-induced cytotoxicity in a three-dimensional co-culture model.

Crabbé A, Sarker SF, Van Houdt R, Ott CM, Leys N, Cornelis P, Nickerson CA.

Cell Microbiol. 2011 Mar;13(3):469-81. doi: 10.1111/j.1462-5822.2010.01548.x. Epub 2010 Nov 25.

PMID:
21054742
24.

Organotypic 3D cell culture models: using the rotating wall vessel to study host-pathogen interactions.

Barrila J, Radtke AL, Crabbé A, Sarker SF, Herbst-Kralovetz MM, Ott CM, Nickerson CA.

Nat Rev Microbiol. 2010 Nov;8(11):791-801. doi: 10.1038/nrmicro2423. Review.

PMID:
20948552
25.

Efficacy of various chemical disinfectants on biofilms formed in spacecraft potable water system components.

Wong WC, Dudinsky LA, Garcia VM, Ott CM, Castro VA.

Biofouling. 2010 Jul;26(5):583-6. doi: 10.1080/08927014.2010.495772.

PMID:
20544435
26.

Media ion composition controls regulatory and virulence response of Salmonella in spaceflight.

Wilson JW, Ott CM, Quick L, Davis R, Höner zu Bentrup K, Crabbé A, Richter E, Sarker S, Barrila J, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Shah M, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, CdeBaca A, Narayan S, Benjamin J, Goulart C, Rupert M, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Porter MD, Pierson DL, Smith SM, Mergeay M, Leys N, Stefanyshyn-Piper HM, Gorie D, Nickerson CA.

PLoS One. 2008;3(12):e3923. doi: 10.1371/journal.pone.0003923. Epub 2008 Dec 12.

27.

Effect of spaceflight on ability of monocytes to respond to endotoxins of gram-negative bacteria.

Kaur I, Simons ER, Kapadia AS, Ott CM, Pierson DL.

Clin Vaccine Immunol. 2008 Oct;15(10):1523-8. doi: 10.1128/CVI.00065-08. Epub 2008 Sep 3.

28.

Closing the phenotypic gap between transformed neuronal cell lines in culture and untransformed neurons.

Myers TA, Nickerson CA, Kaushal D, Ott CM, Höner zu Bentrup K, Ramamurthy R, Nelman-Gonzalez M, Pierson DL, Philipp MT.

J Neurosci Methods. 2008 Sep 15;174(1):31-41. doi: 10.1016/j.jneumeth.2008.06.031. Epub 2008 Jul 10.

29.

Skim milk enhances the preservation of thawed -80 degrees C bacterial stocks.

Cody WL, Wilson JW, Hendrixson DR, McIver KS, Hagman KE, Ott CM, Nickerson CA, Schurr MJ.

J Microbiol Methods. 2008 Sep;75(1):135-8. doi: 10.1016/j.mimet.2008.05.006. Epub 2008 May 14.

30.

Varicella-zoster virus in the saliva of patients with herpes zoster.

Mehta SK, Tyring SK, Gilden DH, Cohrs RJ, Leal MJ, Castro VA, Feiveson AH, Ott CM, Pierson DL.

J Infect Dis. 2008 Mar 1;197(5):654-7. doi: 10.1086/527420.

31.

Studying host-pathogen interactions in 3-D: organotypic models for infectious disease and drug development.

Nickerson CA, Richter EG, Ott CM.

J Neuroimmune Pharmacol. 2007 Mar;2(1):26-31. Epub 2006 Dec 6. Review.

PMID:
18040823
32.

Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq.

Wilson JW, Ott CM, Höner zu Bentrup K, Ramamurthy R, Quick L, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Fernandez D, Richter E, Shah M, Kilcoyne M, Joshi L, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, Goulart C, Rupert M, Stodieck L, Stafford P, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Allen P, Baker-Coleman C, Hammond T, Vogel J, Nelson R, Pierson DL, Stefanyshyn-Piper HM, Nickerson CA.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16299-304. Epub 2007 Sep 27.

33.

Cell signaling. A ciliary signaling switch.

Christensen ST, Ott CM.

Science. 2007 Jul 20;317(5836):330-1. No abstract available.

PMID:
17641189
34.

Characterization of Escherichia coli MG1655 grown in a low-shear modeled microgravity environment.

Tucker DL, Ott CM, Huff S, Fofanov Y, Pierson DL, Willson RC, Fox GE.

BMC Microbiol. 2007 Mar 7;7:15.

35.

Specific features of the prion protein transmembrane domain regulate nascent chain orientation.

Ott CM, Akhavan A, Lingappa VR.

J Biol Chem. 2007 Apr 13;282(15):11163-71. Epub 2007 Feb 2.

36.

Novel quantitative biosystem for modeling physiological fluid shear stress on cells.

Nauman EA, Ott CM, Sander E, Tucker DL, Pierson D, Wilson JW, Nickerson CA.

Appl Environ Microbiol. 2007 Feb;73(3):699-705. Epub 2006 Dec 1.

37.

Three-dimensional organotypic models of human colonic epithelium to study the early stages of enteric salmonellosis.

Höner zu Bentrup K, Ramamurthy R, Ott CM, Emami K, Nelman-Gonzalez M, Wilson JW, Richter EG, Goodwin TJ, Alexander JS, Pierson DL, Pellis N, Buchanan KL, Nickerson CA.

Microbes Infect. 2006 Jun;8(7):1813-25. Epub 2006 Apr 27.

PMID:
16730210
38.

Three-dimensional growth of extravillous cytotrophoblasts promotes differentiation and invasion.

LaMarca HL, Ott CM, Höner Zu Bentrup K, Leblanc CL, Pierson DL, Nelson AB, Scandurro AB, Whitley GS, Nickerson CA, Morris CA.

Placenta. 2005 Nov;26(10):709-20. Epub 2005 Jan 25.

PMID:
16226120
39.

Nuclear pore complex function in Saccharomyces cerevisiae is influenced by glycosylation of the transmembrane nucleoporin Pom152p.

Belanger KD, Gupta A, MacDonald KM, Ott CM, Hodge CA, Cole CM, Davis LI.

Genetics. 2005 Nov;171(3):935-47. Epub 2005 Aug 22.

40.

Changes in monocyte functions of astronauts.

Kaur I, Simons ER, Castro VA, Ott CM, Pierson DL.

Brain Behav Immun. 2005 Nov;19(6):547-54.

PMID:
15908177
41.

A549 lung epithelial cells grown as three-dimensional aggregates: alternative tissue culture model for Pseudomonas aeruginosa pathogenesis.

Carterson AJ, Höner zu Bentrup K, Ott CM, Clarke MS, Pierson DL, Vanderburg CR, Buchanan KL, Nickerson CA, Schurr MJ.

Infect Immun. 2005 Feb;73(2):1129-40.

42.

Signal sequences influence membrane integration of the prion protein.

Ott CM, Lingappa VR.

Biochemistry. 2004 Sep 28;43(38):11973-82.

PMID:
15379537
43.

Microbial responses to microgravity and other low-shear environments.

Nickerson CA, Ott CM, Wilson JW, Ramamurthy R, Pierson DL.

Microbiol Mol Biol Rev. 2004 Jun;68(2):345-61. Review.

44.

Microbial characterization during the early habitation of the International Space Station.

Castro VA, Thrasher AN, Healy M, Ott CM, Pierson DL.

Microb Ecol. 2004 Feb;47(2):119-26. Epub 2004 Feb 2.

PMID:
14749908
45.

Microbial characterization of free floating condensate aboard the Mir space station.

Ott CM, Bruce RJ, Pierson DL.

Microb Ecol. 2004 Feb;47(2):133-6. Epub 2004 Mar 4.

PMID:
14569419
46.

Signal sequences initiate the pathway of maturation in the endoplasmic reticulum lumen.

Rutkowski DT, Ott CM, Polansky JR, Lingappa VR.

J Biol Chem. 2003 Aug 8;278(32):30365-72. Epub 2003 May 27.

47.

Low-shear modeled microgravity: a global environmental regulatory signal affecting bacterial gene expression, physiology, and pathogenesis.

Nickerson CA, Ott CM, Wilson JW, Ramamurthy R, LeBlanc CL, Höner zu Bentrup K, Hammond T, Pierson DL.

J Microbiol Methods. 2003 Jul;54(1):1-11. Review.

PMID:
12732416
48.

Low-Shear modeled microgravity alters the Salmonella enterica serovar typhimurium stress response in an RpoS-independent manner.

Wilson JW, Ott CM, Ramamurthy R, Porwollik S, McClelland M, Pierson DL, Nickerson CA.

Appl Environ Microbiol. 2002 Nov;68(11):5408-16.

49.

Microarray analysis identifies Salmonella genes belonging to the low-shear modeled microgravity regulon.

Wilson JW, Ramamurthy R, Porwollik S, McClelland M, Hammond T, Allen P, Ott CM, Pierson DL, Nickerson CA.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13807-12. Epub 2002 Oct 7.

50.

Integral membrane protein biosynthesis: why topology is hard to predict.

Ott CM, Lingappa VR.

J Cell Sci. 2002 May 15;115(Pt 10):2003-9. Review.

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