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Items: 1 to 50 of 59

1.

Second-generation taxanes effectively suppress subcutaneous rat lymphoma: role of disposition, transport, metabolism, in vitro potency and expression of angiogenesis genes.

Otová B, Ojima I, Václavíková R, Hrdý J, Ehrlichová M, Souček P, Vobořilová J, Němcová V, Zanardi I, Horský S, Kovář J, Gut I.

Invest New Drugs. 2012 Jun;30(3):991-1002. doi: 10.1007/s10637-011-9654-0. Epub 2011 Mar 30.

PMID:
21448670
2.

In vivo modulation of angiogenic gene expression by acyclic nucleoside phosphonates PMEDAP and PMEG.

Otová B, Hrdy J, Votruba I, Holy A.

Anticancer Res. 2009 Apr;29(4):1295-302.

3.

[Acyclic nucleoside phosphonates as potential antineoplastic agents].

Votruba I, Otová B, Holý A.

Cas Lek Cesk. 2008;147(9):471-7. Review. Czech.

PMID:
18988489
4.

Experimental therapy with 9-[2-(phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP): origin of resistance.

Zápotocký M, Hanzalová J, Starková J, Votruba I, Holý A, Otová B.

Folia Biol (Praha). 2007;53(3):79-84.

5.

[Biological mechanisms of aging].

Otová B, Kalvach Z, Snejdrlová M.

Cas Lek Cesk. 2006;145(9):688-94. Review. Czech.

PMID:
17091723
6.

Effects of paclitaxel, docetaxel and their combinations on subcutaneous lymphomas in inbred Sprague-Dawley/Cub rats.

Otová B, Václavíková R, Danielová V, Holubová J, Ehrlichová M, Horský S, Soucek P, Simek P, Gut I.

Eur J Pharm Sci. 2006 Dec;29(5):442-50. Epub 2006 Aug 23.

PMID:
17000091
7.

Inhibition of thymidine phosphorylase (PD-ECGF) from SD-lymphoma by phosphonomethoxyalkyl thymines.

Votruba I, Pomeisl K, Tloust'ová E, Holý A, Otová B.

Biochem Pharmacol. 2005 May 15;69(10):1517-21.

PMID:
15857616
8.

PMEDAP and its N6-substituted derivatives: genotoxic effect and apoptosis in in vitro conditions.

Valeriánová M, Otová B, Bílá V, Hanzalová J, Votruba I, Holý A, Eckschlager T, Krejcí O, Trka J.

Anticancer Res. 2003 Nov-Dec;23(6C):4933-9.

PMID:
14981948
9.

Upregulation of asparagine synthetase fails to avert cell cycle arrest induced by L-asparaginase in TEL/AML1-positive leukaemic cells.

Krejci O, Starkova J, Otova B, Madzo J, Kalinova M, Hrusak O, Trka J.

Leukemia. 2004 Mar;18(3):434-41.

PMID:
14724653
10.

Relevant animal model of human lymphoblastic leukaemia/lymphoma--spontaneous T-cell lymphomas in an inbred Sprague-Dawley rat strain (SD/Cub).

Otová B, Sladká M, Damoiseaux J, Panczak A, Mandys V, Marinov I.

Folia Biol (Praha). 2002;48(6):213-26. Review.

PMID:
12512796
11.
12.

Tenofovir diphosphate is a poor substrate and a weak inhibitor of rat DNA polymerases alpha, delta, and epsilon*.

Birkus G, Hájek M, Kramata P, Votruba I, Holý A, Otová B.

Antimicrob Agents Chemother. 2002 May;46(5):1610-3.

13.

O-Phosphonatomethylcholine, its analogues, alkyl esters, and their biological activity.

Holý A, Otová B, Budesínský M, Emerson D, Wiles ME.

J Med Chem. 2001 Dec 6;44(25):4462-7.

PMID:
11728191
14.

Antitumour activity of a combined treatment with PMEDAP and docetaxel in the Prague inbred Sprague-Dawley/cub rat strain bearing T-cell lymphoma.

Bobkov K, Gut I, Mandys V, Holý A, Votruba I, Otová B.

Anticancer Res. 2001 Jul-Aug;21(4A):2725-31.

PMID:
11724347
15.

Antitumour activity of N6-substituted PMEDAP derivatives against T-cell lymphoma.

Valeriánová M, Votruba I, Holy A, Mandys V, Otová B.

Anticancer Res. 2001 May-Jun;21(3B):2057-64.

PMID:
11497298
16.

Different mechanisms in inhibition of rat macrophage nitric oxide synthase expression by FK 506 and cyclosporin A.

Strestíková P, Otová B, Filipec M, Masek K, Farghali H.

Immunopharmacol Immunotoxicol. 2001 Feb;23(1):67-74.

PMID:
11322650
17.

Inhibitory effect of FK 506 and cyclosporin A on nitric oxide production by LPS-treated cultured rat macrophages.

Strestíková P, Otová B, Filipec M, Farghali H.

Physiol Res. 2000;49(6):725-8.

18.

Anticancer effect of PMEDAP--monitoring of apoptosis.

Bobková K, Otová B, Marinov I, Mandys V, Panczak A, Votruba I, Holý A.

Anticancer Res. 2000 Mar-Apr;20(2A):1041-7.

PMID:
10810395
19.

Therapeutic effect of heat shock on T-cell lymphoma in inbred Sprague-Dawley rat.

Otová B, Mráz M, Mandys V, Panczak A, Schramlová J, Votruba I, Holy A.

Folia Biol (Praha). 1999;45(4):121-31.

PMID:
10732725
20.

Cytogenetic changes in Sprague-Dawley rat lymphomas in the course of in vivo passages.

Sladká M, Otová B.

Folia Biol (Praha). 1998;44(4):143-50.

PMID:
10732704
21.

9-[2-(phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP)--a potential drug against hematological malignancies--induces apoptosis.

Otová B, Francová K, Franĕk F, Koutník P, Votruba I, Holy A, Sladká M, Schramlová J.

Anticancer Res. 1999 Jul-Aug;19(4B):3173-82.

PMID:
10652608
22.
23.

Characterization of T-cell lymphomas in the Prague inbred Sprague-Dawley/cub rat strain: a model of spontaneous hematologic malignancy.

Otová B, Sladká M, Damoiseaux J, Panczak A, Mandys V, Francová K, Kudlácková M.

Transplant Proc. 1999 May;31(3):1618-9. No abstract available.

PMID:
10331023
24.

Graft-versus-host disease in the rat: a genetic analysis in recombinant inbred strains of SHR x BN. Lx and BN. Lx x SHR sets.

Panczak A, Kren V, Bílá V, Pravenec M, Matousková M, Krenová D, Otová B, Sladká M.

Transplant Proc. 1999 May;31(3):1569-70. No abstract available.

PMID:
10331004
25.

Typing of urinary JC virus DNA offers a novel means of tracing human migrations.

Sugimoto C, Kitamura T, Guo J, Al-Ahdal MN, Shchelkunov SN, Otova B, Ondrejka P, Chollet JY, El-Safi S, Ettayebi M, Grésenguet G, Kocagöz T, Chaiyarasamee S, Thant KZ, Thein S, Moe K, Kobayashi N, Taguchi F, Yogo Y.

Proc Natl Acad Sci U S A. 1997 Aug 19;94(17):9191-6.

26.

Biological characteristics of spontaneous transplantable T-cell lymphomas in inbred Sprague-Dawley/cub rats.

Otová B, Sladká M, Panczak A, Marinov I.

Transplant Proc. 1997 May;29(3):1754-5. No abstract available.

PMID:
9142261
27.

Inhibition of acute graft-versus-host disease in (LEW.1W x LEW.1A)F1 rats using 9-(2-phosphonomethoxyethyl)-2,6-diaminopurine.

Otová B, Panczak A, Kohoutová M, Blazek K, Schramlová J, Sladká M, Holý A.

Transplant Proc. 1997 May;29(3):1736-7. No abstract available.

PMID:
9142254
28.

Genetic analysis of graft-versus-host disease using rat recombinant inbred strains.

Panczak A, Bílá V, Sladká M, Krenová D, Otová B, Pravenec M, Kren V.

Transplant Proc. 1997 May;29(3):1734-5. No abstract available.

PMID:
9142253
29.

Antitumor activity of novel purine acyclic nucleotide analogs PMEA and PMEDAP.

Otová B, Zídek Z, Holý A, Votruba I, Sladká M, Marinov I, Lesková V.

In Vivo. 1997 Mar-Apr;11(2):163-7.

PMID:
9179610
30.

Genotoxicity of purine acyclic nucleotide analogs.

Otová B, Holý A, Votruba I, Sladká M, Bílá V, Mejsnarová B, Lesková V.

Folia Biol (Praha). 1997;43(6):225-9.

PMID:
9595265
31.

The effect of an antiphlogistic incorporated in liposomes on experimentally induced inflammation.

Schramlová J, Blazek K, Otová B, Bartácková M, Hulínská D.

Folia Biol (Praha). 1997;43(5):195-9.

PMID:
9595260
32.

Electron microscopic demonstration of the penetration of liposomes through skin.

Schramlová J, Blazek K, Bartácková M, Otová B, Mardesicová L, Zizkovský V, Hulínská D.

Folia Biol (Praha). 1997;43(4):165-9.

PMID:
9338124
33.

Electron microscopic demonstration of the interaction of liposomes and cells in vitro.

Schramlová J, Blazek K, Danielová V, Bartácková M, Holubová J, Otová B, Hulínská D.

Folia Biol (Praha). 1997;43(4):161-4.

PMID:
9338123
34.

Treatment of transplanted spontaneous rat T-cell leukaemia with local administration of recombinant murine interleukin-2.

Otová B, Panczak A, Símová J, Jandlová T, Bubeník J, Blazek K, Schramlová J, Marinov I.

Folia Biol (Praha). 1997;43(1):25-32.

PMID:
9158946
35.
36.

Suppression of rat adjuvant arthritis by some acyclic nucleotide analogs.

Zídek A, Holý A, Franková D, Otová B.

Eur J Pharmacol. 1995 Nov 24;286(3):307-10.

PMID:
8608793
38.

Immunomodulatory properties of 9-(2-phosphonomethoxyethyl)-adenine (PMEA).

Otová B, Zídek Z, Holý A, Votruba I, Franková D.

Folia Biol (Praha). 1994;40(4):185-92.

PMID:
7851616
39.

Chromosome 11 participation in acute lymphoblastic leukaemia in Sprague-Dawley rats.

Sladká M, Otová B.

Folia Biol (Praha). 1994;40(4):173-83.

PMID:
7851615
40.

Electron-microscopic demonstration of virus particles in acute lymphoblastic leukaemia in Sprague-Dawley rats.

Schramlová J, Otová B, Cerný J, Blazek K.

Folia Biol (Praha). 1994;40(3):113-8.

PMID:
7805932
41.

Model of acute graft-vs-host-disease in adult (SHR x BN.lx)F1 rats and its inhibition by adenine analog.

Kren V, Otová B, Elleder D, Elleder M, Panczak A, Sladká M.

Transplant Proc. 1993 Oct;25(5):2822-3. No abstract available.

PMID:
8212248
42.

THY 1.1 and CD43 antigen expression on rat tumor cells.

Krenova D, Otova B, Kren V.

Transplant Proc. 1993 Oct;25(5):2797-8. No abstract available.

PMID:
8105581
43.

Prevention of acute graft-versus-host disease in rats using 9-(2-phosphonomethoxyethyl) adenine (PMEA).

Kren V, Otová B, Elleder D, Elleder M, Panczak A, Holý A.

Folia Biol (Praha). 1993;39(2):78-86.

PMID:
8258370
44.

Antimitotic and teratogenic effects of acyclic nucleotide analogues 1-(S)-(3-hydroxy-2-phosphonomethoxyethyl)cytosine (HPMPC) and 9-(2-phosphonomethoxyethyl) adenine (PMEA).

Bílá V, Otová B, Jelínek R, Sladká M, Mejsnarová B, Holý A, Kren V.

Folia Biol (Praha). 1993;39(3):150-61.

PMID:
8157136
45.

Cytostatic effect of 9-(2-phosphonomethoxyethyl) adenine (PMEA). II. Lymphoblastic leukemia in Sprague-Dawley rats.

Otová B, Sladká M, Blazek K, Schramlová J, Votruba I, Holý A.

Folia Biol (Praha). 1993;39(3):142-9.

PMID:
8157135
46.

Cytostatic effect of 9-(2-phosphonomethoxyethyl) adenine (PMEA). I. Lymphatic leukemia KHP-Lw-I in Lewis rats.

Otová B, Sladká M, Votruba I, Holý A, Kren V.

Folia Biol (Praha). 1993;39(3):136-41.

PMID:
8157134
47.

Cytostatic effect of 9-(2-phosphonomethoxyethyl) adenine (PMEA). III. Rat and mouse carcinomas and sarcomas.

Otová B, Krenová D, Zídek Z, Holý A, Votruba I, Kren V.

Folia Biol (Praha). 1993;39(6):311-4.

PMID:
7926161
49.

[Effectiveness of phosphonoformic acid in herpes infections].

Smejkal F, Otová B, Zikán V, Roubínek F.

Cesk Farm. 1992 Feb;41(1):1-4. Czech.

PMID:
1316808
50.

Detection of nuclear cytomegalovirus antigen in cell culture as compared to classical virus isolation.

Horácek J, Brucek P, Otová B.

Acta Virol. 1991 Apr;35(2):187-9.

PMID:
1681716

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