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Items: 1 to 50 of 520

1.

Design and Evaluation of An Extended-Release Olmesartan Tablet Using Chitosan/Cyclodextrin Composites.

Anraku M, Tabuchi R, Goto M, Iohara D, Mizukai Y, Maezaki Y, Michihara A, Kadowaki D, Otagiri M, Hirayama F.

Pharmaceutics. 2019 Feb 15;11(2). pii: E82. doi: 10.3390/pharmaceutics11020082.

2.

Further Evidence Regarding the Important Role of Chlorine Atoms of Aripiprazole on Binding to the Site II Area of Human Albumin.

Sakurama K, Nishi K, Imoto S, Hashimoto M, Komatsu T, Morita Y, Taguchi K, Otagiri M, Yamasaki K.

J Pharm Sci. 2018 Dec 8. pii: S0022-3549(18)30795-0. doi: 10.1016/j.xphs.2018.11.045. [Epub ahead of print]

PMID:
30537471
3.

Glutamine Deprivation Enhances Acetyl-CoA Carboxylase Inhibitor-induced Death of Human Pancreatic Cancer Cells.

Nishi K, Suzuki M, Yamamoto N, Matsumoto A, Iwase Y, Yamasaki K, Otagiri M, Yumita N.

Anticancer Res. 2018 Dec;38(12):6683-6689. doi: 10.21873/anticanres.13036.

PMID:
30504377
4.

Use of hemoglobin for delivering exogenous carbon monoxide in medicinal applications.

Taguchi K, Maruyama T, Otagiri M.

Curr Med Chem. 2018 Nov 13. doi: 10.2174/0929867325666181113122340. [Epub ahead of print]

PMID:
30421669
5.

Analysis of the Binding of Aripiprazole to Human Serum Albumin: The Importance of a Chloro-Group in the Chemical Structure.

Sakurama K, Kawai A, Tuan Giam Chuang V, Kanamori Y, Osa M, Taguchi K, Seo H, Maruyama T, Imoto S, Yamasaki K, Otagiri M.

ACS Omega. 2018 Oct 31;3(10):13790-13797. doi: 10.1021/acsomega.8b02057. Epub 2018 Oct 22.

6.

Antioxidant activities of chitosans and its derivatives in in vitro and in vivo studies.

Anraku M, Gebicki JM, Iohara D, Tomida H, Uekama K, Maruyama T, Hirayama F, Otagiri M.

Carbohydr Polym. 2018 Nov 1;199:141-149. doi: 10.1016/j.carbpol.2018.07.016. Epub 2018 Jul 7. Review.

PMID:
30143114
7.

Benzbromarone Attenuates Oxidative Stress in Angiotensin II- and Salt-Induced Hypertensive Model Rats.

Muraya N, Kadowaki D, Miyamura S, Kitamura K, Uchimura K, Narita Y, Miyamoto Y, Chuang VTG, Taguchi K, Maruyama T, Otagiri M, Hirata S.

Oxid Med Cell Longev. 2018 Jun 5;2018:7635274. doi: 10.1155/2018/7635274. eCollection 2018.

8.

Pharmacokinetic properties of a novel inosine analog, 4'-cyano-2'-deoxyinosine, after oral administration in rats.

Hashimoto M, Taguchi K, Ishiguro T, Kohgo S, Imoto S, Yamasaki K, Mitsuya H, Otagiri M.

PLoS One. 2018 Jun 6;13(6):e0198636. doi: 10.1371/journal.pone.0198636. eCollection 2018.

9.

Metal-catalyzed oxidation of human serum albumin does not alter the interactive binding to the two principal drug binding sites.

Yamasaki K, Nishi K, Anraku M, Taguchi K, Maruyama T, Otagiri M.

Biochem Biophys Rep. 2018 May 11;14:155-160. doi: 10.1016/j.bbrep.2018.05.002. eCollection 2018 Jul.

10.

Biomimetic carbon monoxide delivery based on hemoglobin vesicles ameliorates acute pancreatitis in mice via the regulation of macrophage and neutrophil activity.

Taguchi K, Nagao S, Maeda H, Yanagisawa H, Sakai H, Yamasaki K, Wakayama T, Watanabe H, Otagiri M, Maruyama T.

Drug Deliv. 2018 Nov;25(1):1266-1274. doi: 10.1080/10717544.2018.1477860.

11.

Development of Kupffer cell targeting type-I interferon for the treatment of hepatitis via inducing anti-inflammatory and immunomodulatory actions.

Minayoshi Y, Maeda H, Yanagisawa H, Hamasaki K, Mizuta Y, Nishida K, Kinoshita R, Enoki Y, Imafuku T, Chuang VTG, Koga T, Fujiwara Y, Takeya M, Sonoda K, Wakayama T, Taguchi K, Ishima Y, Ishida T, Iwakiri Y, Tanaka M, Sasaki Y, Watanabe H, Otagiri M, Maruyama T.

Drug Deliv. 2018 Nov;25(1):1067-1077. doi: 10.1080/10717544.2018.1464083.

12.

Preparation and in Vitro Analysis of Human Serum Albumin Nanoparticles Loaded with Anthracycline Derivatives.

Kimura K, Yamasaki K, Nakamura H, Haratake M, Taguchi K, Otagiri M.

Chem Pharm Bull (Tokyo). 2018;66(4):382-390. doi: 10.1248/cpb.c17-00838.

13.

Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery.

Ichimizu S, Watanabe H, Maeda H, Hamasaki K, Nakamura Y, Chuang VTG, Kinoshita R, Nishida K, Tanaka R, Enoki Y, Ishima Y, Kuniyasu A, Kobashigawa Y, Morioka H, Futaki S, Otagiri M, Maruyama T.

J Control Release. 2018 May 10;277:23-34. doi: 10.1016/j.jconrel.2018.02.037. Epub 2018 Mar 10.

PMID:
29530390
14.

Pharmacokinetics studies of 4'-cyano-2'-deoxyguanosine, a potent inhibitor of the hepatitis B virus, in rats.

Hashimoto M, Taguchi K, Ishiguro T, Kohgo S, Imoto S, Yamasaki K, Mitsuya H, Otagiri M.

J Pharm Pharmacol. 2018 Jun;70(6):723-731. doi: 10.1111/jphp.12897. Epub 2018 Mar 12.

PMID:
29528116
15.

Crystal structure analysis of human serum albumin complexed with sodium 4-phenylbutyrate.

Kawai A, Yamasaki K, Enokida T, Miyamoto S, Otagiri M.

Biochem Biophys Rep. 2018 Jan 28;13:78-82. doi: 10.1016/j.bbrep.2018.01.006. eCollection 2018 Mar.

16.

Trp residue at subsite - 5 plays a critical role in the substrate binding of two protistan GH26 β-mannanases from a termite hindgut.

Hsu Y, Koizumi H, Otagiri M, Moriya S, Arioka M.

Appl Microbiol Biotechnol. 2018 Feb;102(4):1737-1747. doi: 10.1007/s00253-017-8726-2. Epub 2018 Jan 5.

PMID:
29305697
17.

Thioredoxin-albumin fusion protein prevents copper enhanced zinc-induced neurotoxicity via its antioxidative activity.

Tanaka KI, Shimoda M, Chuang VTG, Nishida K, Kawahara M, Ishida T, Otagiri M, Maruyama T, Ishima Y.

Int J Pharm. 2018 Jan 15;535(1-2):140-147. doi: 10.1016/j.ijpharm.2017.11.012. Epub 2017 Nov 6.

PMID:
29122608
18.

Dual Therapeutic Effects of an Albumin-Based Nitric Oxide Donor on 2 Experimental Models of Chronic Kidney Disease.

Oshiro S, Ishima Y, Maeda H, Honda N, Bi J, Kinoshita R, Ikeda M, Iwao Y, Imafuku T, Nishida K, Miyamura S, Watanabe H, Otagiri M, Maruyama T.

J Pharm Sci. 2018 Mar;107(3):848-855. doi: 10.1016/j.xphs.2017.10.023. Epub 2017 Oct 24.

PMID:
29074377
19.

A novel S-sulfhydrated human serum albumin preparation suppresses melanin synthesis.

Ikeda M, Ishima Y, Kinoshita R, Chuang VTG, Tasaka N, Matsuo N, Watanabe H, Shimizu T, Ishida T, Otagiri M, Maruyama T.

Redox Biol. 2018 Apr;14:354-360. doi: 10.1016/j.redox.2017.10.007. Epub 2017 Oct 11.

20.

Recombinant Human Serum Albumin Containing 3 Copies of Domain I, Has Significant in Vitro Antioxidative Capacity Compared to the Wild-Type.

Matsushita S, Nishi K, Iwao Y, Ishima Y, Watanabe H, Taguchi K, Yamasaki K, Maruyama T, Otagiri M.

Biol Pharm Bull. 2017;40(10):1813-1817. doi: 10.1248/bpb.b17-00528.

21.

Parathyroid hormone contributes to the down-regulation of cytochrome P450 3A through the cAMP/PI3K/PKC/PKA/NF-κB signaling pathway in secondary hyperparathyroidism.

Watanabe H, Sugimoto R, Ikegami K, Enoki Y, Imafuku T, Fujimura R, Bi J, Nishida K, Sakaguchi Y, Murata M, Maeda H, Hirata K, Jingami S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T.

Biochem Pharmacol. 2017 Dec 1;145:192-201. doi: 10.1016/j.bcp.2017.08.016. Epub 2017 Aug 24.

PMID:
28843775
22.

Albumin-Encapsulated Liposomes: A Novel Drug Delivery Carrier With Hydrophobic Drugs Encapsulated in the Inner Aqueous Core.

Okamoto Y, Taguchi K, Yamasaki K, Sakuragi M, Kuroda S, Otagiri M.

J Pharm Sci. 2018 Jan;107(1):436-445. doi: 10.1016/j.xphs.2017.08.003. Epub 2017 Aug 18.

PMID:
28826882
23.

Surface-deacetylated chitin nanofibers reinforced with a sulfobutyl ether β-cyclodextrin gel loaded with prednisolone as potential therapy for inflammatory bowel disease.

Tabuchi R, Anraku M, Iohara D, Ishiguro T, Ifuku S, Nagae T, Uekama K, Okazaki S, Takeshita K, Otagiri M, Hirayama F.

Carbohydr Polym. 2017 Oct 15;174:1087-1094. doi: 10.1016/j.carbpol.2017.07.028. Epub 2017 Jul 13.

PMID:
28821031
24.

Novel squalene-producing thraustochytrids found in mangrove water.

Otagiri M, Khalid A, Moriya S, Osada H, Takahashi S.

Biosci Biotechnol Biochem. 2017 Oct;81(10):2034-2037. doi: 10.1080/09168451.2017.1359485. Epub 2017 Aug 10.

PMID:
28795620
25.

A Comparison of the Phosphorus Content in Prescription Medications for Hemodialysis Patients in Japan.

Shimoishi K, Anraku M, Uto A, Iohara D, Hirayama F, Kadowaki D, Zingami S, Maruyama T, Otagiri M.

Yakugaku Zasshi. 2017;137(7):903-908. doi: 10.1248/yakushi.17-00006.

26.

Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin.

Yamasaki K, Hyodo S, Taguchi K, Nishi K, Yamaotsu N, Hirono S, Chuang VTG, Seo H, Maruyama T, Otagiri M.

PLoS One. 2017 Jun 29;12(6):e0180404. doi: 10.1371/journal.pone.0180404. eCollection 2017.

27.

Improved anticancer effects of albumin-bound paclitaxel nanoparticle via augmentation of EPR effect and albumin-protein interactions using S-nitrosated human serum albumin dimer.

Kinoshita R, Ishima Y, Chuang VTG, Nakamura H, Fang J, Watanabe H, Shimizu T, Okuhira K, Ishida T, Maeda H, Otagiri M, Maruyama T.

Biomaterials. 2017 Sep;140:162-169. doi: 10.1016/j.biomaterials.2017.06.021. Epub 2017 Jun 22.

PMID:
28651144
28.

Potential therapeutic interventions for chronic kidney disease-associated sarcopenia via indoxyl sulfate-induced mitochondrial dysfunction.

Enoki Y, Watanabe H, Arake R, Fujimura R, Ishiodori K, Imafuku T, Nishida K, Sugimoto R, Nagao S, Miyamura S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T.

J Cachexia Sarcopenia Muscle. 2017 Oct;8(5):735-747. doi: 10.1002/jcsm.12202. Epub 2017 Jun 12.

29.

Comparison of the pharmacological and biological properties of HPMA copolymer-pirarubicin conjugates: A single-chain copolymer conjugate and its biodegradable tandem-diblock copolymer conjugate.

Etrych T, Tsukigawa K, Nakamura H, Chytil P, Fang J, Ulbrich K, Otagiri M, Maeda H.

Eur J Pharm Sci. 2017 Aug 30;106:10-19. doi: 10.1016/j.ejps.2017.05.031. Epub 2017 May 18.

PMID:
28528285
30.

Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions.

Kawai A, Chuang VTG, Kouno Y, Yamasaki K, Miyamoto S, Anraku M, Otagiri M.

Biochim Biophys Acta Proteins Proteom. 2017 Aug;1865(8):979-984. doi: 10.1016/j.bbapap.2017.04.004. Epub 2017 May 1.

PMID:
28473296
31.

Species Differences in the Binding of Sodium 4-Phenylbutyrate to Serum Albumin.

Yamasaki K, Enokida T, Taguchi K, Miyamura S, Kawai A, Miyamoto S, Maruyama T, Seo H, Otagiri M.

J Pharm Sci. 2017 Sep;106(9):2860-2867. doi: 10.1016/j.xphs.2017.04.025. Epub 2017 Apr 26.

PMID:
28456727
32.

The Use of Hemoglobin Vesicles for Delivering Medicinal Gas for the Treatment of Intractable Disorders.

Taguchi K, Yamasaki K, Sakai H, Maruyama T, Otagiri M.

J Pharm Sci. 2017 Sep;106(9):2392-2400. doi: 10.1016/j.xphs.2017.04.006. Epub 2017 Apr 13. Review.

PMID:
28414143
33.

Apoptosis induction of poly-S-nitrosated human serum albumin in resistant solid tumor under hypoxia can be restored by phosphodiesterase 5 inhibition.

Ikeda M, Ishima Y, Chuang VTG, Ikeda T, Kinoshita R, Watanabe H, Ishida T, Otagiri M, Maruyama T.

Nitric Oxide. 2017 Sep 30;69:28-34. doi: 10.1016/j.niox.2017.04.005. Epub 2017 Apr 13.

PMID:
28414103
34.

Quantitative determination of polysulfide in albumins, plasma proteins and biological fluid samples using a novel combined assays approach.

Ikeda M, Ishima Y, Shibata A, Chuang VTG, Sawa T, Ihara H, Watanabe H, Xian M, Ouchi Y, Shimizu T, Ando H, Ukawa M, Ishida T, Akaike T, Otagiri M, Maruyama T.

Anal Chim Acta. 2017 May 29;969:18-25. doi: 10.1016/j.aca.2017.03.027. Epub 2017 Mar 22.

PMID:
28411626
35.

Comparison of the Pharmacokinetic Properties of Hemoglobin-Based Oxygen Carriers.

Taguchi K, Yamasaki K, Maruyama T, Otagiri M.

J Funct Biomater. 2017 Mar 18;8(1). pii: E11. doi: 10.3390/jfb8010011. Review.

36.

Clinical Implications Associated With the Posttranslational Modification-Induced Functional Impairment of Albumin in Oxidative Stress-Related Diseases.

Watanabe H, Imafuku T, Otagiri M, Maruyama T.

J Pharm Sci. 2017 Sep;106(9):2195-2203. doi: 10.1016/j.xphs.2017.03.002. Epub 2017 Mar 14. Review.

PMID:
28302542
37.

The Binding of Silibinin, the Main Constituent of Silymarin, to Site I on Human Serum Albumin.

Yamasaki K, Sato H, Minagoshi S, Kyubun K, Anraku M, Miyamura S, Watanabe H, Taguchi K, Seo H, Maruyama T, Otagiri M.

Biol Pharm Bull. 2017;40(3):310-317. doi: 10.1248/bpb.b16-00790.

38.

An oral absorbent, surface-deacetylated chitin nano-fiber ameliorates renal injury and oxidative stress in 5/6 nephrectomized rats.

Anraku M, Tabuchi R, Ifuku S, Nagae T, Iohara D, Tomida H, Uekama K, Maruyama T, Miyamura S, Hirayama F, Otagiri M.

Carbohydr Polym. 2017 Apr 1;161:21-25. doi: 10.1016/j.carbpol.2016.12.057. Epub 2016 Dec 23.

PMID:
28189231
39.

Down-regulation of ABCG2, a urate exporter, by parathyroid hormone enhances urate accumulation in secondary hyperparathyroidism.

Sugimoto R, Watanabe H, Ikegami K, Enoki Y, Imafuku T, Sakaguchi Y, Murata M, Nishida K, Miyamura S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T.

Kidney Int. 2017 Mar;91(3):658-670. doi: 10.1016/j.kint.2016.09.041. Epub 2016 Dec 15.

PMID:
27988213
40.

Oral branched-chain amino acid granules improve structure and function of human serum albumin in cirrhotic patients.

Setoyama H, Tanaka M, Nagumo K, Naoe H, Watanabe T, Yoshimaru Y, Tateyama M, Sasaki M, Watanabe H, Otagiri M, Maruyama T, Sasaki Y.

J Gastroenterol. 2017 Jun;52(6):754-765. doi: 10.1007/s00535-016-1281-2. Epub 2016 Nov 21.

41.

Carbon monoxide-bound hemoglobin vesicles ameliorate multiorgan injuries induced by severe acute pancreatitis in mice by their anti-inflammatory and antioxidant properties.

Nagao S, Taguchi K, Sakai H, Yamasaki K, Watanabe H, Otagiri M, Maruyama T.

Int J Nanomedicine. 2016 Oct 27;11:5611-5620. eCollection 2016.

42.
43.

Human serum albumin hydropersulfide is a potent reactive oxygen species scavenger in oxidative stress conditions such as chronic kidney disease.

Shibata A, Ishima Y, Ikeda M, Sato H, Imafuku T, Chuang VTG, Ouchi Y, Abe T, Watanabe H, Ishida T, Otagiri M, Maruyama T.

Biochem Biophys Res Commun. 2016 Oct 21;479(3):578-583. doi: 10.1016/j.bbrc.2016.09.113. Epub 2016 Sep 23.

PMID:
27666483
44.

Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1.

Enoki Y, Watanabe H, Arake R, Sugimoto R, Imafuku T, Tominaga Y, Ishima Y, Kotani S, Nakajima M, Tanaka M, Matsushita K, Fukagawa M, Otagiri M, Maruyama T.

Sci Rep. 2016 Aug 23;6:32084. doi: 10.1038/srep32084.

45.

Biomaterials based on freeze dried surface-deacetylated chitin nanofibers reinforced with sulfobutyl ether β-cyclodextrin gel in wound dressing applications.

Tabuchi R, Azuma K, Izumi R, Tanou T, Okamoto Y, Nagae T, Iohara D, Uekama K, Otagiri M, Hirayama F, Ifuku S, Anraku M.

Int J Pharm. 2016 Sep 25;511(2):1080-7. doi: 10.1016/j.ijpharm.2016.08.019. Epub 2016 Aug 10.

PMID:
27521704
46.

The Development of a Novel, Validated, Rapid and Simple Method for the Detection of Sarcocystis fayeri in Horse Meat in the Sanitary Control Setting.

Furukawa M, Minegishi Y, Izumiyama S, Yagita K, Mori H, Uemura T, Etoh Y, Maeda E, Sasaki M, Ichinose K, Harada S, Kamata Y, Otagiri M, Sugita-Konishi Y, Ohnishi T.

Biocontrol Sci. 2016;21(2):131-4. doi: 10.4265/bio.21.131.

47.

Oral pharmacokinetics and in-vitro metabolism of metyrapone in male rats.

Murata H, Higuchi T, Otagiri M.

J Pharm Pharmacol. 2016 Aug;68(8):970-9. doi: 10.1111/jphp.12560. Epub 2016 Jun 5.

PMID:
27265478
48.

Effect of a Ferric Citrate Formulation, a Phosphate Binder, on Oxidative Stress in Chronic Kidney Diseases-Mineral and Bone Disorder Patients Receiving Hemodialysis: A Pilot Study.

Tanaka M, Miyamura S, Imafuku T, Tominaga Y, Maeda H, Anraku M, Yamasaki K, Kadowaki D, Ishima Y, Watanabe H, Okuda T, Itoh K, Matsushita K, Fukagawa M, Otagiri M, Maruyama T.

Biol Pharm Bull. 2016;39(6):1000-6. doi: 10.1248/bpb.b15-01021.

49.

Evaluation of a new type of nano-sized carbon monoxide donor on treating mice with experimentally induced colitis.

Nagao S, Taguchi K, Miyazaki Y, Wakayama T, Chuang VT, Yamasaki K, Watanabe H, Sakai H, Otagiri M, Maruyama T.

J Control Release. 2016 Jul 28;234:49-58. doi: 10.1016/j.jconrel.2016.05.016. Epub 2016 May 9.

PMID:
27173944
50.

Tyrosine411 and Arginine410 of Human Serum Albumin Play an Important Role in the Binding of Sodium 4-Phenylbutyrate to Site II.

Enokida T, Yamasaki K, Okamoto Y, Taguchi K, Ishiguro T, Maruyama T, Seo H, Otagiri M.

J Pharm Sci. 2016 Jun;105(6):1987-1994. doi: 10.1016/j.xphs.2016.03.012. Epub 2016 Apr 22.

PMID:
27113474

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