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Items: 22


Local and Systemic CD4+ T Cell Exhaustion Reverses with Clinical Resolution of Pulmonary Sarcoidosis.

Hawkins C, Shaginurova G, Shelton DA, Herazo-Maya JD, Oswald-Richter KA, Rotsinger JE, Young A, Celada LJ, Kaminski N, Sevin C, Drake WP.

J Immunol Res. 2017;2017:3642832. doi: 10.1155/2017/3642832. Epub 2017 Nov 6.


Blockade of the programmed death-1 pathway restores sarcoidosis CD4(+) T-cell proliferative capacity.

Braun NA, Celada LJ, Herazo-Maya JD, Abraham S, Shaginurova G, Sevin CM, Grutters J, Culver DA, Dworski R, Sheller J, Massion PP, Polosukhin VV, Johnson JE, Kaminski N, Wilkes DS, Oswald-Richter KA, Drake WP.

Am J Respir Crit Care Med. 2014 Sep 1;190(5):560-71. doi: 10.1164/rccm.201401-0188OC.


Effects of broad-spectrum antimycobacterial therapy on chronic pulmonary sarcoidosis.

Drake WP, Richmond BW, Oswald-Richter K, Yu C, Isom JM, Worrell JA, Shipley GR.

Sarcoidosis Vasc Diffuse Lung Dis. 2013 Nov 25;30(3):201-11.


The invasive chytrid fungus of amphibians paralyzes lymphocyte responses.

Fites JS, Ramsey JP, Holden WM, Collier SP, Sutherland DM, Reinert LK, Gayek AS, Dermody TS, Aune TM, Oswald-Richter K, Rollins-Smith LA.

Science. 2013 Oct 18;342(6156):366-9. doi: 10.1126/science.1243316.


Oral antimycobacterial therapy in chronic cutaneous sarcoidosis: a randomized, single-masked, placebo-controlled study.

Drake WP, Oswald-Richter K, Richmond BW, Isom J, Burke VE, Algood H, Braun N, Taylor T, Pandit KV, Aboud C, Yu C, Kaminski N, Boyd AS, King LE.

JAMA Dermatol. 2013 Sep;149(9):1040-9. doi: 10.1001/jamadermatol.2013.4646.


Reversal of global CD4+ subset dysfunction is associated with spontaneous clinical resolution of pulmonary sarcoidosis.

Oswald-Richter KA, Richmond BW, Braun NA, Isom J, Abraham S, Taylor TR, Drake JM, Culver DA, Wilkes DS, Drake WP.

J Immunol. 2013 Jun 1;190(11):5446-53. doi: 10.4049/jimmunol.1202891. Epub 2013 Apr 29.


Sarcoidosis Th17 cells are ESAT-6 antigen specific but demonstrate reduced IFN-γ expression.

Richmond BW, Ploetze K, Isom J, Chambers-Harris I, Braun NA, Taylor T, Abraham S, Mageto Y, Culver DA, Oswald-Richter KA, Drake WP.

J Clin Immunol. 2013 Feb;33(2):446-55. doi: 10.1007/s10875-012-9817-6. Epub 2012 Oct 18.


Dual analysis for mycobacteria and propionibacteria in sarcoidosis BAL.

Oswald-Richter KA, Beachboard DC, Seeley EH, Abraham S, Shepherd BE, Jenkins CA, Culver DA, Caprioli RM, Drake WP.

J Clin Immunol. 2012 Oct;32(5):1129-40. doi: 10.1007/s10875-012-9700-5. Epub 2012 May 3.


Necrotising enterocolitis is characterised by disrupted immune regulation and diminished mucosal regulatory (FOXP3)/effector (CD4, CD8) T cell ratios.

Weitkamp JH, Koyama T, Rock MT, Correa H, Goettel JA, Matta P, Oswald-Richter K, Rosen MJ, Engelhardt BG, Moore DJ, Polk DB.

Gut. 2013 Jan;62(1):73-82. doi: 10.1136/gutjnl-2011-301551. Epub 2012 Jan 20.


Enzyme-linked immunospot assay (ELISPOT): Quantification of Th-1 cellular immune responses against microbial antigens.

Chambers IR, Cone TR, Oswald-Richter K, Drake WP.

J Vis Exp. 2010 Nov 23;(45). pii: 2221. doi: 10.3791/2221.


Multiple mycobacterial antigens are targets of the adaptive immune response in pulmonary sarcoidosis.

Oswald-Richter KA, Beachboard DC, Zhan X, Gaskill CF, Abraham S, Jenkins C, Culver DA, Drake W.

Respir Res. 2010 Nov 23;11:161. doi: 10.1186/1465-9921-11-161.


The etiologic role of infectious antigens in sarcoidosis pathogenesis.

Oswald-Richter KA, Drake WP.

Semin Respir Crit Care Med. 2010 Aug;31(4):375-9. doi: 10.1055/s-0030-1262205. Epub 2010 Jul 27.


Development of a sarcoidosis murine lung granuloma model using Mycobacterium superoxide dismutase A peptide.

Swaisgood CM, Oswald-Richter K, Moeller SD, Klemenc JM, Ruple LM, Farver CF, Drake JM, Culver DA, Drake WP.

Am J Respir Cell Mol Biol. 2011 Feb;44(2):166-74. doi: 10.1165/rcmb.2009-0350OC. Epub 2010 Mar 26.


Cellular responses to mycobacterial antigens are present in bronchoalveolar lavage fluid used in the diagnosis of sarcoidosis.

Oswald-Richter KA, Culver DA, Hawkins C, Hajizadeh R, Abraham S, Shepherd BE, Jenkins CA, Judson MA, Drake WP.

Infect Immun. 2009 Sep;77(9):3740-8. doi: 10.1128/IAI.00142-09. Epub 2009 Jul 13.


Mycobacterial ESAT-6 and katG are recognized by sarcoidosis CD4+ T cells when presented by the American sarcoidosis susceptibility allele, DRB1*1101.

Oswald-Richter K, Sato H, Hajizadeh R, Shepherd BE, Sidney J, Sette A, Newman LS, Drake WP.

J Clin Immunol. 2010 Jan;30(1):157-66. doi: 10.1007/s10875-009-9311-y. Epub 2009 Jun 18.


Naive precursors of human regulatory T cells require FoxP3 for suppression and are susceptible to HIV infection.

Antons AK, Wang R, Oswald-Richter K, Tseng M, Arendt CW, Kalams SA, Unutmaz D.

J Immunol. 2008 Jan 15;180(2):764-73.


Identification of a CCR5-expressing T cell subset that is resistant to R5-tropic HIV infection.

Oswald-Richter K, Grill SM, Leelawong M, Tseng M, Kalams SA, Hulgan T, Haas DW, Unutmaz D.

PLoS Pathog. 2007 Apr;3(4):e58.


Helicobacter pylori VacA toxin inhibits human immunodeficiency virus infection of primary human T cells.

Oswald-Richter K, Torres VJ, Sundrud MS, VanCompernolle SE, Cover TL, Unutmaz D.

J Virol. 2006 Dec;80(23):11767-75. Epub 2006 Sep 27.


Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance.

Dillon S, Agrawal S, Banerjee K, Letterio J, Denning TL, Oswald-Richter K, Kasprowicz DJ, Kellar K, Pare J, van Dyke T, Ziegler S, Unutmaz D, Pulendran B.

J Clin Invest. 2006 Apr;116(4):916-28.


Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells.

VanCompernolle SE, Taylor RJ, Oswald-Richter K, Jiang J, Youree BE, Bowie JH, Tyler MJ, Conlon JM, Wade D, Aiken C, Dermody TS, KewalRamani VN, Rollins-Smith LA, Unutmaz D.

J Virol. 2005 Sep;79(18):11598-606.


HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells.

Oswald-Richter K, Grill SM, Shariat N, Leelawong M, Sundrud MS, Haas DW, Unutmaz D.

PLoS Biol. 2004 Jul;2(7):E198. Epub 2004 Jul 13.


HIV infection of primary human T cells is determined by tunable thresholds of T cell activation.

Oswald-Richter K, Grill SM, Leelawong M, Unutmaz D.

Eur J Immunol. 2004 Jun;34(6):1705-14.

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