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Items: 29

1.

A chiral wedge molecule inhibits telomerase activity.

Shinohara K, Sannohe Y, Kaieda S, Tanaka K, Osuga H, Tahara H, Xu Y, Kawase T, Bando T, Sugiyama H.

J Am Chem Soc. 2010 Mar 24;132(11):3778-82. doi: 10.1021/ja908897j.

PMID:
20192187
2.
3.

A dopamine receptor antagonist L-745,870 suppresses microglia activation in spinal cord and mitigates the progression in ALS model mice.

Tanaka K, Okada Y, Kanno T, Otomo A, Yanagisawa Y, Shouguchi-Miyata J, Suga E, Kohiki E, Onoe K, Osuga H, Aoki M, Hadano S, Itoyama Y, Ikeda JE.

Exp Neurol. 2008 Jun;211(2):378-86. doi: 10.1016/j.expneurol.2008.02.004. Epub 2008 Mar 4.

PMID:
18423451
4.

ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth.

Otomo A, Kunita R, Suzuki-Utsunomiya K, Mizumura H, Onoe K, Osuga H, Hadano S, Ikeda JE.

Biochem Biophys Res Commun. 2008 May 23;370(1):87-92. doi: 10.1016/j.bbrc.2008.01.177. Epub 2008 Mar 19.

PMID:
18358238
5.

Synthesis and properties of a series of well-defined and polydisperse benzo[1,2-b:4,3-b']dithiophene oligomers.

Nishide Y, Osuga H, Saito M, Aiba T, Inagaki Y, Doge Y, Tanaka K.

J Org Chem. 2007 Nov 23;72(24):9141-51. Epub 2007 Oct 25.

PMID:
17958444
6.

ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics.

Suzuki-Utsunomiya K, Hadano S, Otomo A, Kunita R, Mizumura H, Osuga H, Ikeda JE.

Biochem Biophys Res Commun. 2007 Mar 9;354(2):491-7. Epub 2007 Jan 11.

PMID:
17239822
7.

The recognition of higher-order G-quadruplex by chiral cyclic-helicene molecules.

Xu Y, Yamazaki S, Osuga H, Sugiyama H.

Nucleic Acids Symp Ser (Oxf). 2006;(50):183-4.

PMID:
17150878
8.

The recognition of Z-DNA by chiral helicene.

Xu Y, Sugiyama H, Tanaka K, Osuga H.

Nucleic Acids Symp Ser (Oxf). 2004;(48):87-8.

PMID:
17150491
9.

A dopamine D4 receptor antagonist attenuates ischemia-induced neuronal cell damage via upregulation of neuronal apoptosis inhibitory protein.

Okada Y, Sakai H, Kohiki E, Suga E, Yanagisawa Y, Tanaka K, Hadano S, Osuga H, Ikeda JE.

J Cereb Blood Flow Metab. 2005 Jul;25(7):794-806.

PMID:
15729293
10.

(P)-helicene displays chiral selection in binding to Z-DNA.

Xu Y, Zhang YX, Sugiyama H, Umano T, Osuga H, Tanaka K.

J Am Chem Soc. 2004 Jun 2;126(21):6566-7.

PMID:
15161280
11.

ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics.

Otomo A, Hadano S, Okada T, Mizumura H, Kunita R, Nishijima H, Showguchi-Miyata J, Yanagisawa Y, Kohiki E, Suga E, Yasuda M, Osuga H, Nishimoto T, Narumiya S, Ikeda JE.

Hum Mol Genet. 2003 Jul 15;12(14):1671-87.

PMID:
12837691
12.
13.

Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat.

Wang F, Corbett D, Osuga H, Osuga S, Ikeda JE, Slack RS, Hogan MJ, Hakim AM, Park DS.

J Cereb Blood Flow Metab. 2002 Feb;22(2):171-82.

PMID:
11823715
14.

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.

Hadano S, Hand CK, Osuga H, Yanagisawa Y, Otomo A, Devon RS, Miyamoto N, Showguchi-Miyata J, Okada Y, Singaraja R, Figlewicz DA, Kwiatkowski T, Hosler BA, Sagie T, Skaug J, Nasir J, Brown RH Jr, Scherer SW, Rouleau GA, Hayden MR, Ikeda JE.

Nat Genet. 2001 Oct;29(2):166-73.

PMID:
11586298
15.

Identification and characterization of the miniature pig Huntington's disease gene homolog: evidence for conservation and polymorphism in the CAG triplet repeat.

Matsuyama N, Hadano S, Onoe K, Osuga H, Showguchi-Miyata J, Gondo Y, Ikeda JE.

Genomics. 2000 Oct 1;69(1):72-85.

PMID:
11013077
16.

Cyclin-dependent kinases as a therapeutic target for stroke.

Osuga H, Osuga S, Wang F, Fetni R, Hogan MJ, Slack RS, Hakim AM, Ikeda JE, Park DS.

Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10254-9.

17.

Neuronal apoptosis inhibitory protein (NAIP) may enhance the survival of granulosa cells thus indirectly affecting oocyte survival.

Matsumoto K, Nakayama T, Sakai H, Tanemura K, Osuga H, Sato E, Ikeda JE.

Mol Reprod Dev. 1999 Oct;54(2):103-11.

PMID:
10471469
18.
19.

In vivo uptake of [3H]nimodipine into brain during cortical spreading depression.

Osuga S, Hakim AM, Osuga H, Hogan MJ.

J Cereb Blood Flow Metab. 1997 May;17(5):586-90.

PMID:
9183298
21.

Relevance of interstitial glutamate to selective vulnerability in focal cerebral ischemia.

Osuga H, Hakim AM.

J Cereb Blood Flow Metab. 1994 Mar;14(2):343-7.

PMID:
7906692
22.
23.

[Treatment of mitral valve regurgitation in endocardial cushion defect].

Kagawa Y, Osuga H, Horiuchi T.

Kyobu Geka. 1974 May;27(5):360-2. Japanese. No abstract available.

PMID:
4471948
24.

[Case of renal vascular hypertension assumed to be due to an injury].

Suzuki Y, Tomita Y, Osuga H, Miura Y.

Geka Chiryo. 1971 Oct;25(4):477-81. Japanese. No abstract available.

PMID:
5172155
25.

[SUCESSFUL TREATMENT OF A CASE OF PNEUMOCOCCAL MENINGITIS WITH LONG-TERM COMBINED THERAPY OF ANTIBIOTICS AND ADRENAL CORTEX HORMONES].

KATSU M, YAMAMOTO I, NORMURA K, OSUGA H.

Naika. 1964 Jul;14:153-6. Japanese. No abstract available.

PMID:
14175324
26.

[Current drug therapy].

KATSU M, YASU M, OSUGA H.

Chiryo. 1963 Apr;45:656-64. Japanese. No abstract available.

PMID:
13958448
27.

[Effects of chemotherapy on bacillary dysentery--particularly with a small dose of antibiotics].

FUJIMORI I, OGAWA JI, ITO S, OSUGA H, OME S.

Keio J Med. 1962 Mar;39:261-6. Japanese. No abstract available.

28.

[On the cholesterol-clearing action of choleretics].

GOTO Y, KATAYAMA T, OSUGA H.

Chiryo. 1961 Dec;43:2205-10. Japanese. No abstract available.

PMID:
13900728
29.

[Behavior of leukocytes from the standpoint of respiration in murine typhuc immunization].

OSUGA H.

Paediatr Jpn. 1961 Aug 1;65:829-34. Japanese. No abstract available.

PMID:
13731557

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