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Items: 1 to 50 of 117

1.

Identification of genetic variants in CFAP221 as a cause of primary ciliary dyskinesia.

Bustamante-Marin XM, Shapiro A, Sears PR, Charng WL, Conrad DF, Leigh MW, Knowles MR, Ostrowski LE, Zariwala MA.

J Hum Genet. 2019 Oct 21. doi: 10.1038/s10038-019-0686-1. [Epub ahead of print]

PMID:
31636325
2.

Dysmature superficial white matter microstructure in developmental focal epilepsy.

Ostrowski LM, Song DY, Thorn EL, Ross EE, Stoyell SM, Chinappen DM, Eden UT, Kramer MA, Emerton BC, Morgan AK, Stufflebeam SM, Chu CJ.

Brain Commun. 2019;1(1):fcz002. doi: 10.1093/braincomms/fcz002. Epub 2019 Jun 19.

3.

Phase Separation as a Melting Pot for DNA Repeats.

Hall AC, Ostrowski LA, Mekhail K.

Trends Genet. 2019 Aug;35(8):589-600. doi: 10.1016/j.tig.2019.05.001. Epub 2019 May 31. Review.

PMID:
31155151
4.

Scalp recorded spike ripples predict seizure risk in childhood epilepsy better than spikes.

Kramer MA, Ostrowski LM, Song DY, Thorn EL, Stoyell SM, Parnes M, Chinappen D, Xiao G, Eden UT, Staley KJ, Stufflebeam SM, Chu CJ.

Brain. 2019 May 1;142(5):1296-1309. doi: 10.1093/brain/awz059.

PMID:
30907404
5.

Mice with a Deletion of Rsph1 Exhibit a Low Level of Mucociliary Clearance and Develop a Primary Ciliary Dyskinesia Phenotype.

Yin W, Livraghi-Butrico A, Sears PR, Rogers TD, Burns KA, Grubb BR, Ostrowski LE.

Am J Respir Cell Mol Biol. 2019 Sep;61(3):312-321. doi: 10.1165/rcmb.2017-0387OC.

PMID:
30896965
6.

Demographics and anthropometrics impact benefits of health intervention: data from the Reduce Obesity and Diabetes Project.

Ostrowski L, Speiser PW, Accacha S, Altshuler L, Fennoy I, Lowell B, Rapaport R, Rosenfeld W, Shelov SP, Ten S, Rosenbaum M; ROAD Group.

Obes Sci Pract. 2019 Jan 16;5(1):46-58. doi: 10.1002/osp4.310. eCollection 2019 Feb.

7.

Beta oscillations in the sensorimotor cortex correlate with disease and remission in benign epilepsy with centrotemporal spikes.

Song DY, Stoyell SM, Ross EE, Ostrowski LM, Thorn EL, Stufflebeam SM, Morgan AK, Emerton BC, Kramer MA, Chu CJ.

Brain Behav. 2019 Mar;9(3):e01237. doi: 10.1002/brb3.1237. Epub 2019 Feb 20.

8.

Lack of GAS2L2 Causes PCD by Impairing Cilia Orientation and Mucociliary Clearance.

Bustamante-Marin XM, Yin WN, Sears PR, Werner ME, Brotslaw EJ, Mitchell BJ, Jania CM, Zeman KL, Rogers TD, Herring LE, Refabért L, Thomas L, Amselem S, Escudier E, Legendre M, Grubb BR, Knowles MR, Zariwala MA, Ostrowski LE.

Am J Hum Genet. 2019 Feb 7;104(2):229-245. doi: 10.1016/j.ajhg.2018.12.009. Epub 2019 Jan 18.

9.

Conserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeats.

Ostrowski LA, Hall AC, Szafranski KJ, Oshidari R, Abraham KJ, Chan JNY, Krustev C, Zhang K, Wang A, Liu Y, Guo R, Mekhail K.

Commun Biol. 2018 Nov 5;1:187. doi: 10.1038/s42003-018-0187-3. eCollection 2018.

10.

Mucociliary Clearance in Mice Measured by Tracking Trans-tracheal Fluorescence of Nasally Aerosolized Beads.

Rogers TD, Ostrowski LE, Livraghi-Butrico A, Button B, Grubb BR.

Sci Rep. 2018 Oct 3;8(1):14744. doi: 10.1038/s41598-018-33053-2.

11.

Closed-loop system to enhance slow-wave activity.

Garcia-Molina G, Tsoneva T, Jasko J, Steele B, Aquino A, Baher K, Pastoor S, Pfundtner S, Ostrowski L, Miller B, Papas N, Riedner B, Tononi G, White DP.

J Neural Eng. 2018 Dec;15(6):066018. doi: 10.1088/1741-2552/aae18f. Epub 2018 Sep 14.

PMID:
30215604
12.

Investigating Teliospore Germination Using Microrespiration Analysis and Microdissection.

Ostrowski LA, Seto AM, Saville B.

J Vis Exp. 2018 May 13;(135). doi: 10.3791/57628.

PMID:
29806843
13.

Dual-core all-fiber integrated immunosensor for detection of protein antigens.

Wysokiński K, Budnicki D, Fidelus J, Szostkiewicz Ł, Ostrowski Ł, Murawski M, Staniszewski M, Staniszewska M, Napierała M, Nasiłowski T.

Biosens Bioelectron. 2018 Aug 30;114:22-29. doi: 10.1016/j.bios.2018.05.008. Epub 2018 May 9.

PMID:
29775855
14.

Primary ciliary dyskinesia: keep it on your radar.

Rosenfeld M, Ostrowski LE, Zariwala MA.

Thorax. 2018 Feb;73(2):101-102. doi: 10.1136/thoraxjnl-2017-210776. Epub 2017 Nov 13. No abstract available.

15.

Ataxin-2: From RNA Control to Human Health and Disease.

Ostrowski LA, Hall AC, Mekhail K.

Genes (Basel). 2017 Jun 5;8(6). pii: E157. doi: 10.3390/genes8060157. Review.

16.

Transcriptome analysis of smut fungi reveals widespread intergenic transcription and conserved antisense transcript expression.

Donaldson ME, Ostrowski LA, Goulet KM, Saville BJ.

BMC Genomics. 2017 May 2;18(1):340. doi: 10.1186/s12864-017-3720-8.

17.

The Validation of a School-Based, Culturally Grounded Drug Prevention Curriculum for Rural Hawaiian Youth.

Okamoto SK, Helm S, Ostrowski LK, Flood L.

Health Promot Pract. 2018 May;19(3):369-376. doi: 10.1177/1524839917704210. Epub 2017 Apr 26.

18.

Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes.

Hall AC, Ostrowski LA, Pietrobon V, Mekhail K.

Nucleus. 2017 Mar 4;8(2):162-181. doi: 10.1080/19491034.2017.1292193. Review.

19.

Direct monitoring of pulmonary disease treatment biomarkers using plasmonic gold nanorods with diffusion-sensitive OCT.

Blackmon RL, Kreda SM, Sears PR, Chapman BS, Hill DB, Tracy JB, Ostrowski LE, Oldenburg AL.

Nanoscale. 2017 Apr 13;9(15):4907-4917. doi: 10.1039/c7nr00376e.

20.

Quantitative Proteomic Analysis of Human Airway Cilia Identifies Previously Uncharacterized Proteins of High Abundance.

Blackburn K, Bustamante-Marin X, Yin W, Goshe MB, Ostrowski LE.

J Proteome Res. 2017 Apr 7;16(4):1579-1592. doi: 10.1021/acs.jproteome.6b00972. Epub 2017 Mar 27.

21.

High-speed and high-sensitivity parallel spectral-domain optical coherence tomography using a supercontinuum light source.

Barrick J, Doblas A, Gardner MR, Sears PR, Ostrowski LE, Oldenburg AL.

Opt Lett. 2016 Dec 15;41(24):5620-5623. doi: 10.1364/OL.41.005620.

22.

Natural antisense transcripts are linked to the modulation of mitochondrial function and teliospore dormancy in Ustilago maydis.

Ostrowski LA, Saville BJ.

Mol Microbiol. 2017 Mar;103(5):745-763. doi: 10.1111/mmi.13587. Epub 2017 Jan 9.

23.

Cilia and Mucociliary Clearance.

Bustamante-Marin XM, Ostrowski LE.

Cold Spring Harb Perspect Biol. 2017 Apr 3;9(4). pii: a028241. doi: 10.1101/cshperspect.a028241. Review.

24.

Diffusion-sensitive optical coherence tomography for real-time monitoring of mucus thinning treatments.

Blackmon RL, Kreda SM, Sears PR, Ostrowski LE, Hill DB, Chapman BS, Tracy JB, Oldenburg AL.

Proc SPIE Int Soc Opt Eng. 2016;9697. pii: 969724.

25.

Tensor decomposition in potential energy surface representations.

Ostrowski L, Ziegler B, Rauhut G.

J Chem Phys. 2016 Sep 14;145(10):104103. doi: 10.1063/1.4962368.

PMID:
27634247
26.

Non-Coding RNA Molecules Connect Calorie Restriction and Lifespan.

Abraham KJ, Ostrowski LA, Mekhail K.

J Mol Biol. 2017 Oct 27;429(21):3196-3214. doi: 10.1016/j.jmb.2016.08.020. Epub 2016 Aug 22. Review.

PMID:
27561708
27.

Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin.

Grubb BR, Livraghi-Butrico A, Rogers TD, Yin W, Button B, Ostrowski LE.

Am J Physiol Lung Cell Mol Physiol. 2016 May 1;310(9):L860-7. doi: 10.1152/ajplung.00015.2016. Epub 2016 Mar 11.

28.

The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia.

Turner MJ, Matthes E, Billet A, Ferguson AJ, Thomas DY, Randell SH, Ostrowski LE, Abbott-Banner K, Hanrahan JW.

Am J Physiol Lung Cell Mol Physiol. 2016 Jan 1;310(1):L59-70. doi: 10.1152/ajplung.00324.2015. Epub 2015 Nov 6.

29.

Continuous mucociliary transport by primary human airway epithelial cells in vitro.

Sears PR, Yin WN, Ostrowski LE.

Am J Physiol Lung Cell Mol Physiol. 2015 Jul 15;309(2):L99-108. doi: 10.1152/ajplung.00024.2015. Epub 2015 May 15.

30.

Cryo-electron tomography reveals ciliary defects underlying human RSPH1 primary ciliary dyskinesia.

Lin J, Yin W, Smith MC, Song K, Leigh MW, Zariwala MA, Knowles MR, Ostrowski LE, Nicastro D.

Nat Commun. 2014 Dec 4;5:5727. doi: 10.1038/ncomms6727.

31.

Genetic regulation of Zfp30, CXCL1, and neutrophilic inflammation in murine lung.

Rutledge H, Aylor DL, Carpenter DE, Peck BC, Chines P, Ostrowski LE, Chesler EJ, Churchill GA, de Villena FP, Kelada SN.

Genetics. 2014 Oct;198(2):735-45. doi: 10.1534/genetics.114.168138. Epub 2014 Aug 11.

32.

Mutations in RSPH1 cause primary ciliary dyskinesia with a unique clinical and ciliary phenotype.

Knowles MR, Ostrowski LE, Leigh MW, Sears PR, Davis SD, Wolf WE, Hazucha MJ, Carson JL, Olivier KN, Sagel SD, Rosenfeld M, Ferkol TW, Dell SD, Milla CE, Randell SH, Yin W, Sannuti A, Metjian HM, Noone PG, Noone PJ, Olson CA, Patrone MV, Dang H, Lee HS, Hurd TW, Gee HY, Otto EA, Halbritter J, Kohl S, Kircher M, Krischer J, Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Zariwala MA.

Am J Respir Crit Care Med. 2014 Mar 15;189(6):707-17. doi: 10.1164/rccm.201311-2047OC.

33.

Restoring ciliary function to differentiated primary ciliary dyskinesia cells with a lentiviral vector.

Ostrowski LE, Yin W, Patel M, Sechelski J, Rogers T, Burns K, Grubb BR, Olsen JC.

Gene Ther. 2014 Mar;21(3):253-61. doi: 10.1038/gt.2013.79. Epub 2014 Jan 23.

34.

Mutations in SPAG1 cause primary ciliary dyskinesia associated with defective outer and inner dynein arms.

Knowles MR, Ostrowski LE, Loges NT, Hurd T, Leigh MW, Huang L, Wolf WE, Carson JL, Hazucha MJ, Yin W, Davis SD, Dell SD, Ferkol TW, Sagel SD, Olivier KN, Jahnke C, Olbrich H, Werner C, Raidt J, Wallmeier J, Pennekamp P, Dougherty GW, Hjeij R, Gee HY, Otto EA, Halbritter J, Chaki M, Diaz KA, Braun DA, Porath JD, Schueler M, Baktai G, Griese M, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Hildebrandt F, Shendure J, Omran H, Zariwala MA.

Am J Hum Genet. 2013 Oct 3;93(4):711-20. doi: 10.1016/j.ajhg.2013.07.025. Epub 2013 Sep 19.

35.

Exome sequencing identifies mutations in CCDC114 as a cause of primary ciliary dyskinesia.

Knowles MR, Leigh MW, Ostrowski LE, Huang L, Carson JL, Hazucha MJ, Yin W, Berg JS, Davis SD, Dell SD, Ferkol TW, Rosenfeld M, Sagel SD, Milla CE, Olivier KN, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Shendure J, Zariwala MA; Genetic Disorders of Mucociliary Clearance Consortium.

Am J Hum Genet. 2013 Jan 10;92(1):99-106. doi: 10.1016/j.ajhg.2012.11.003. Epub 2012 Dec 20.

36.

Is cystatin C valuable marker of glomerular filtration rate in living kidney donors after uninephrectomy?

Bieniasz M, Kwiatkowski A, Gozdowska J, Domagala P, Kieszek R, Drozdowski J, Ostrowski L, Zygier D, Lazowski T, Chmura A.

Transplant Proc. 2012 Dec;44(10):2910-2. doi: 10.1016/j.transproceed.2012.05.087. Epub 2012 Nov 3.

PMID:
23194995
37.
38.

Computer-assisted image analysis of human cilia and Chlamydomonas flagella reveals both similarities and differences in axoneme structure.

O'Toole ET, Giddings TH Jr, Porter ME, Ostrowski LE.

Cytoskeleton (Hoboken). 2012 Aug;69(8):577-90. doi: 10.1002/cm.21035. Epub 2012 May 22.

39.

Congenital heart disease and the specification of left-right asymmetry.

Francis RJ, Christopher A, Devine WA, Ostrowski L, Lo C.

Am J Physiol Heart Circ Physiol. 2012 May 15;302(10):H2102-11. doi: 10.1152/ajpheart.01118.2011. Epub 2012 Mar 9.

40.

Transgenic hCFTR expression fails to correct β-ENaC mouse lung disease.

Grubb BR, O'Neal WK, Ostrowski LE, Kreda SM, Button B, Boucher RC.

Am J Physiol Lung Cell Mol Physiol. 2012 Jan 15;302(2):L238-47. doi: 10.1152/ajplung.00083.2011. Epub 2011 Oct 14.

41.

Cilia and models for studying structure and function.

Ostrowski LE, Dutcher SK, Lo CW.

Proc Am Thorac Soc. 2011 Sep;8(5):423-9. doi: 10.1513/pats.201103-027SD. Review.

42.

Tubulin polyglutamylation is essential for airway ciliary function through the regulation of beating asymmetry.

Ikegami K, Sato S, Nakamura K, Ostrowski LE, Setou M.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10490-5. doi: 10.1073/pnas.1002128107. Epub 2010 May 24.

43.

FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain.

Jacquet BV, Salinas-Mondragon R, Liang H, Therit B, Buie JD, Dykstra M, Campbell K, Ostrowski LE, Brody SL, Ghashghaei HT.

Development. 2009 Dec;136(23):4021-31. doi: 10.1242/dev.041129.

44.

Conditional deletion of dnaic1 in a murine model of primary ciliary dyskinesia causes chronic rhinosinusitis.

Ostrowski LE, Yin W, Rogers TD, Busalacchi KB, Chua M, O'Neal WK, Grubb BR.

Am J Respir Cell Mol Biol. 2010 Jul;43(1):55-63. doi: 10.1165/rcmb.2009-0118OC. Epub 2009 Aug 12.

45.

Ion transport across CF and normal murine olfactory and ciliated epithelium.

Grubb BR, Rogers TD, Boucher RC, Ostrowski LE.

Am J Physiol Cell Physiol. 2009 Jun;296(6):C1301-9. doi: 10.1152/ajpcell.00578.2008. Epub 2009 Mar 25.

46.

Expression of CFTR from a ciliated cell-specific promoter is ineffective at correcting nasal potential difference in CF mice.

Ostrowski LE, Yin W, Diggs PS, Rogers TD, O'Neal WK, Grubb BR.

Gene Ther. 2007 Oct;14(20):1492-501. Epub 2007 Jul 19.

PMID:
17637798
47.

Olfactory epithelia exhibit progressive functional and morphological defects in CF mice.

Grubb BR, Rogers TD, Kulaga HM, Burns KA, Wonsetler RL, Reed RR, Ostrowski LE.

Am J Physiol Cell Physiol. 2007 Aug;293(2):C574-83. Epub 2007 Apr 11.

48.

Best practices: Utilizing risk-of-violence findings for continuity of care.

Ignelzi J, Stinson B, Raia J, Osinowo T, Ostrowski L, Schwirian J; Forensic Risk Assessment Work Group of the Ohio Department of Mental Health's statewide Forensic Product Line Leadership Team.

Psychiatr Serv. 2007 Apr;58(4):452-4.

PMID:
17412843
49.

Lung development and repair: contribution of the ciliated lineage.

Rawlins EL, Ostrowski LE, Randell SH, Hogan BL.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):410-7. Epub 2006 Dec 28.

50.

Primary ciliary dyskinesia and upper airway diseases.

Kennedy MP, Ostrowski LE.

Curr Allergy Asthma Rep. 2006 Nov;6(6):513-7. Review.

PMID:
17026878

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