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Items: 35


Bacillus thuringiensis Cry5B is active against Strongyloides stercoralis in vitro.

Charuchaibovorn S, Sanprasert V, Sutthanont N, Hu Y, Abraham A, Ostroff GR, Aroian RV, Jaleta TG, Lok JB, Nuchprayoon S.

Am J Trop Med Hyg. 2019 Sep 16. doi: 10.4269/ajtmh.19-0083. [Epub ahead of print]


RNA isolation from Peyer's patch lymphocytes and mononuclear phagocytes to determine gene expression profiles using NanoString technology.

Singh N, Gallagher HC, Song R, Dhinsa JK, Ostroff GR, De Jesus M.

J Biol Methods. 2018 Jul 2;5(3):e95. doi: 10.14440/jbm.2018.246. eCollection 2018.


A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection.

Noon JB, Schwarz EM, Ostroff GR, Aroian RV.

PLoS Negl Trop Dis. 2019 Apr 22;13(4):e0007345. doi: 10.1371/journal.pntd.0007345. eCollection 2019 Apr.


Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles.

Whelan AO, Flick-Smith HC, Homan J, Shen ZT, Carpenter Z, Khoshkenar P, Abraham A, Walker NJ, Levitz SM, Ostroff GR, Oyston PCF.

PLoS One. 2018 Oct 8;13(10):e0200213. doi: 10.1371/journal.pone.0200213. eCollection 2018.


Beta-glucan-induced inflammatory monocytes mediate antitumor efficacy in the murine lung.

Alexander MP, Fiering SN, Ostroff GR, Cramer RA, Mullins DW.

Cancer Immunol Immunother. 2018 Nov;67(11):1731-1742. doi: 10.1007/s00262-018-2234-9. Epub 2018 Aug 23.


Glucan-Chitin Particles Enhance Th17 Response and Improve Protective Efficacy of a Multivalent Antigen (rCpa1) against Pulmonary Coccidioides posadasii Infection.

Hung CY, Zhang H, Castro-Lopez N, Ostroff GR, Khoshlenar P, Abraham A, Cole GT, Negron A, Forsthuber T, Peng T, Galgiani JN, Ampel NM, Yu JJ.

Infect Immun. 2018 Oct 25;86(11). pii: e00070-18. doi: 10.1128/IAI.00070-18. Print 2018 Nov.


Bacillus thuringiensis Cry5B protein as a new pan-hookworm cure.

Hu Y, Nguyen TT, Lee ACY, Urban JF Jr, Miller MM, Zhan B, Koch DJ, Noon JB, Abraham A, Fujiwara RT, Bowman DD, Ostroff GR, Aroian RV.

Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):287-294. doi: 10.1016/j.ijpddr.2018.05.001. Epub 2018 May 4.


Vaccination with an alkaline extract of Histoplasma capsulatum packaged in glucan particles confers protective immunity in mice.

Deepe GS Jr, Buesing WR, Ostroff GR, Abraham A, Specht CA, Huang H, Levitz SM.

Vaccine. 2018 May 31;36(23):3359-3367. doi: 10.1016/j.vaccine.2018.04.047. Epub 2018 May 2.


Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species.

Specht CA, Lee CK, Huang H, Hester MM, Liu J, Luckie BA, Torres Santana MA, Mirza Z, Khoshkenar P, Abraham A, Shen ZT, Lodge JK, Akalin A, Homan J, Ostroff GR, Levitz SM.

MBio. 2017 Nov 28;8(6). pii: e01872-17. doi: 10.1128/mBio.01872-17.


Beta-Glucan Particles as Vaccine Adjuvant Carriers.

Mirza Z, Soto ER, Dikengil F, Levitz SM, Ostroff GR.

Methods Mol Biol. 2017;1625:143-157. doi: 10.1007/978-1-4939-7104-6_11.


Targeted Delivery of Glucan Particle Encapsulated Gallium Nanoparticles Inhibits HIV Growth in Human Macrophages.

Soto ER, O'Connell O, Dikengil F, Peters PJ, Clapham PR, Ostroff GR.

J Drug Deliv. 2016;2016:8520629. Epub 2016 Nov 14.


Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts.

Specht CA, Lee CK, Huang H, Tipper DJ, Shen ZT, Lodge JK, Leszyk J, Ostroff GR, Levitz SM.

MBio. 2015 Dec 22;6(6):e01905-15. doi: 10.1128/mBio.01905-15.


Sampling of Candida albicans and Candida tropicalis by Langerin-positive dendritic cells in mouse Peyer's patches.

De Jesus M, Rodriguez AE, Yagita H, Ostroff GR, Mantis NJ.

Immunol Lett. 2015 Nov;168(1):64-72. doi: 10.1016/j.imlet.2015.09.008. Epub 2015 Sep 16.


Exploiting fungal cell wall components in vaccines.

Levitz SM, Huang H, Ostroff GR, Specht CA.

Semin Immunopathol. 2015 Mar;37(2):199-207. doi: 10.1007/s00281-014-0460-6. Epub 2014 Nov 18. Review.


Spectrum and mechanisms of inflammasome activation by chitosan.

Bueter CL, Lee CK, Wang JP, Ostroff GR, Specht CA, Levitz SM.

J Immunol. 2014 Jun 15;192(12):5943-51. doi: 10.4049/jimmunol.1301695. Epub 2014 May 14.


A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling β-glucan microparticles.

De Jesus M, Ostroff GR, Levitz SM, Bartling TR, Mantis NJ.

PLoS One. 2014 Mar 14;9(3):e91002. doi: 10.1371/journal.pone.0091002. eCollection 2014.


HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation.

Träger U, Andre R, Lahiri N, Magnusson-Lind A, Weiss A, Grueninger S, McKinnon C, Sirinathsinghji E, Kahlon S, Pfister EL, Moser R, Hummerich H, Antoniou M, Bates GP, Luthi-Carter R, Lowdell MW, Björkqvist M, Ostroff GR, Aronin N, Tabrizi SJ.

Brain. 2014 Mar;137(Pt 3):819-33. doi: 10.1093/brain/awt355. Epub 2014 Jan 22.


Novel strategies to enhance vaccine immunity against coccidioidomycosis.

Cole GT, Hung CY, Sanderson SD, Hurtgen BJ, Wüthrich M, Klein BS, Deepe GS, Ostroff GR, Levitz SM.

PLoS Pathog. 2013;9(12):e1003768. doi: 10.1371/journal.ppat.1003768. Epub 2013 Dec 19. No abstract available.


β-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination.

De Smet R, Demoor T, Verschuere S, Dullaers M, Ostroff GR, Leclercq G, Allais L, Pilette C, Dierendonck M, De Geest BG, Cuvelier CA.

J Control Release. 2013 Dec 28;172(3):671-8. doi: 10.1016/j.jconrel.2013.09.007. Epub 2013 Sep 14.


Characterization and optimization of the glucan particle-based vaccine platform.

Huang H, Ostroff GR, Lee CK, Specht CA, Levitz SM.

Clin Vaccine Immunol. 2013 Oct;20(10):1585-91. doi: 10.1128/CVI.00463-13. Epub 2013 Aug 14.


Construction and evaluation of a novel recombinant T cell epitope-based vaccine against Coccidioidomycosis.

Hurtgen BJ, Hung CY, Ostroff GR, Levitz SM, Cole GT.

Infect Immun. 2012 Nov;80(11):3960-74. doi: 10.1128/IAI.00566-12. Epub 2012 Sep 4.


Relative contributions of dectin-1 and complement to immune responses to particulate β-glucans.

Huang H, Ostroff GR, Lee CK, Agarwal S, Ram S, Rice PA, Specht CA, Levitz SM.

J Immunol. 2012 Jul 1;189(1):312-7. doi: 10.4049/jimmunol.1200603. Epub 2012 May 30.


Glucan particles for macrophage targeted delivery of nanoparticles.

Soto ER, Caras AC, Kut LC, Castle MK, Ostroff GR.

J Drug Deliv. 2012;2012:143524. doi: 10.1155/2012/143524. Epub 2011 Oct 13.


Linkage specificity and role of properdin in activation of the alternative complement pathway by fungal glycans.

Agarwal S, Specht CA, Haibin H, Ostroff GR, Ram S, Rice PA, Levitz SM.

MBio. 2011 Aug 30;2(5). pii: e00178-11. doi: 10.1128/mBio.00178-11. Print 2011.


Glucan particles for selective delivery of siRNA to phagocytic cells in mice.

Tesz GJ, Aouadi M, Prot M, Nicoloro SM, Boutet E, Amano SU, Goller A, Wang M, Guo CA, Salomon WE, Virbasius JV, Baum RA, O'Connor MJ Jr, Soto E, Ostroff GR, Czech MP.

Biochem J. 2011 Jun 1;436(2):351-62. doi: 10.1042/BJ20110352.


Robust stimulation of humoral and cellular immune responses following vaccination with antigen-loaded beta-glucan particles.

Huang H, Ostroff GR, Lee CK, Specht CA, Levitz SM.

MBio. 2010 Jul 20;1(3). pii: e00164-10. doi: 10.1128/mBio.00164-10.


Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation.

Aouadi M, Tesz GJ, Nicoloro SM, Wang M, Chouinard M, Soto E, Ostroff GR, Czech MP.

Nature. 2009 Apr 30;458(7242):1180-4. doi: 10.1038/nature07774.


Distinct patterns of dendritic cell cytokine release stimulated by fungal beta-glucans and toll-like receptor agonists.

Huang H, Ostroff GR, Lee CK, Wang JP, Specht CA, Levitz SM.

Infect Immun. 2009 May;77(5):1774-81. doi: 10.1128/IAI.00086-09. Epub 2009 Mar 9.


Characterization of multilayered nanoparticles encapsulated in yeast cell wall particles for DNA delivery.

Soto ER, Ostroff GR.

Bioconjug Chem. 2008 Apr;19(4):840-8. doi: 10.1021/bc700329p. Epub 2008 Apr 1.


A comparison of the pulmonary inflammatory potential of different components of yeast cell wall.

Young SH, Ostroff GR, Zeidler-Erdely PC, Roberts JR, Antonini JM, Castranova V.

J Toxicol Environ Health A. 2007 Jul;70(13):1116-24.


Mechanism by which orally administered beta-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models.

Hong F, Yan J, Baran JT, Allendorf DJ, Hansen RD, Ostroff GR, Xing PX, Cheung NK, Ross GD.

J Immunol. 2004 Jul 15;173(2):797-806.


Beta-glucan functions as an adjuvant for monoclonal antibody immunotherapy by recruiting tumoricidal granulocytes as killer cells.

Hong F, Hansen RD, Yan J, Allendorf DJ, Baran JT, Ostroff GR, Ross GD.

Cancer Res. 2003 Dec 15;63(24):9023-31.

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