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Items: 11


Machine Learning on Sequential Data Using a Recurrent Weighted Average.

Ostmeyer J, Cowell L.

Neurocomputing. 2019 Feb 28;331:281-288. doi: 10.1016/j.neucom.2018.11.066. Epub 2018 Nov 29.


Biophysicochemical Motifs in T-cell Receptor Sequences Distinguish Repertoires from Tumor-Infiltrating Lymphocyte and Adjacent Healthy Tissue.

Ostmeyer J, Christley S, Toby IT, Cowell LG.

Cancer Res. 2019 Apr 1;79(7):1671-1680. doi: 10.1158/0008-5472.CAN-18-2292. Epub 2019 Jan 8.


Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel.

Li J, Ostmeyer J, Cuello LG, Perozo E, Roux B.

J Gen Physiol. 2018 Oct 1;150(10):1408-1420. doi: 10.1085/jgp.201812082. Epub 2018 Aug 2.


VDJServer: A Cloud-Based Analysis Portal and Data Commons for Immune Repertoire Sequences and Rearrangements.

Christley S, Scarborough W, Salinas E, Rounds WH, Toby IT, Fonner JM, Levin MK, Kim M, Mock SA, Jordan C, Ostmeyer J, Buntzman A, Rubelt F, Davila ML, Monson NL, Scheuermann RH, Cowell LG.

Front Immunol. 2018 May 8;9:976. doi: 10.3389/fimmu.2018.00976. eCollection 2018.


Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation.

Li J, Ostmeyer J, Boulanger E, Rui H, Perozo E, Roux B.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11145-11150. doi: 10.1073/pnas.1706983114. Epub 2017 Oct 2.


Statistical classifiers for diagnosing disease from immune repertoires: a case study using multiple sclerosis.

Ostmeyer J, Christley S, Rounds WH, Toby I, Greenberg BM, Monson NL, Cowell LG.

BMC Bioinformatics. 2017 Sep 7;18(1):401. doi: 10.1186/s12859-017-1814-6.


Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy.

Kratochvil HT, Maj M, Matulef K, Annen AW, Ostmeyer J, Perozo E, Roux B, Valiyaveetil FI, Zanni MT.

J Am Chem Soc. 2017 Jul 5;139(26):8837-8845. doi: 10.1021/jacs.7b01594. Epub 2017 May 12.


Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy.

Kratochvil HT, Carr JK, Matulef K, Annen AW, Li H, Maj M, Ostmeyer J, Serrano AL, Raghuraman H, Moran SD, Skinner JL, Perozo E, Roux B, Valiyaveetil FI, Zanni MT.

Science. 2016 Sep 2;353(6303):1040-1044.


Quantitative analysis of the water occupancy around the selectivity filter of a K+ channel in different gating modes.

Weingarth M, van der Cruijsen EA, Ostmeyer J, Lievestro S, Roux B, Baldus M.

J Am Chem Soc. 2014 Feb 5;136(5):2000-7. doi: 10.1021/ja411450y. Epub 2014 Jan 22.


Recovery from slow inactivation in K+ channels is controlled by water molecules.

Ostmeyer J, Chakrapani S, Pan AC, Perozo E, Roux B.

Nature. 2013 Sep 5;501(7465):121-4. doi: 10.1038/nature12395. Epub 2013 Jul 28.


Heuristically optimal path scanning for high-speed multiphoton circuit imaging.

Sadovsky AJ, Kruskal PB, Kimmel JM, Ostmeyer J, Neubauer FB, MacLean JN.

J Neurophysiol. 2011 Sep;106(3):1591-8. doi: 10.1152/jn.00334.2011. Epub 2011 Jun 29.

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