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Items: 1 to 50 of 101

1.

A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury.

Grigorieva IV, Oszwald A, Grigorieva EF, Schachner H, Neudert B, Ostendorf T, Floege J, Lindenmeyer MT, Cohen CD, Panzer U, Aigner C, Schmidt A, Grosveld F, Thakker RV, Rees AJ, Kain R.

J Am Soc Nephrol. 2019 Aug 12. pii: ASN.2018111143. doi: 10.1681/ASN.2018111143. [Epub ahead of print]

PMID:
31405951
2.

High-fat diet-induced obesity causes an inflammatory microenvironment in the kidneys of aging Long-Evans rats.

Laurentius T, Raffetseder U, Fellner C, Kob R, Nourbakhsh M, Floege J, Bertsch T, Bollheimer LC, Ostendorf T.

J Inflamm (Lond). 2019 Jun 25;16:14. doi: 10.1186/s12950-019-0219-x. eCollection 2019.

3.

American Academy of Neurology members' preparedness to treat sexual and gender minorities.

Rosendale N, Ostendorf T, Evans DA, Weathers A, Sico JJ, Randall J, Hinson HE.

Neurology. 2019 Jul 23;93(4):159-166. doi: 10.1212/WNL.0000000000007829. Epub 2019 Jun 14.

PMID:
31201295
4.

Production and formulation of a new low-cost biosurfactant to remediate oil-contaminated seawater.

Ostendorf TA, Silva IA, Converti A, Sarubbo LA.

J Biotechnol. 2019 Apr 10;295:71-79. doi: 10.1016/j.jbiotec.2019.01.025. Epub 2019 Mar 12.

PMID:
30871886
5.

Identification of platelet-derived growth factor C as a mediator of both renal fibrosis and hypertension.

van Roeyen CRC, Martin IV, Drescher A, Schuett KA, Hermert D, Raffetseder U, Otten S, Buhl EM, Braun GS, Kuppe C, Liehn E, Boor P, Weiskirchen R, Eriksson U, Gross O, Eitner F, Floege J, Ostendorf T.

Kidney Int. 2019 May;95(5):1103-1119. doi: 10.1016/j.kint.2018.11.031. Epub 2019 Feb 28.

PMID:
30827511
6.

YB-1 increases glomerular, but decreases interstitial fibrosis in CNI-induced nephropathy.

Gibbert L, Hermert D, Wang J, M Breitkopf D, Alidousty C, Neusser M, Cohen CD, Gröne E, Macheleidt I, Rauen T, Braun GS, Floege J, Ostendorf T, Raffetseder U.

Clin Immunol. 2018 Sep;194:67-74. doi: 10.1016/j.clim.2018.07.002. Epub 2018 Jul 3.

PMID:
30018024
7.

CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis.

Eymael J, Sharma S, Loeven MA, Wetzels JF, Mooren F, Florquin S, Deegens JK, Willemsen BK, Sharma V, van Kuppevelt TH, Bakker MA, Ostendorf T, Moeller MJ, Dijkman HB, Smeets B, van der Vlag J.

Kidney Int. 2018 Mar;93(3):626-642. doi: 10.1016/j.kint.2017.09.020. Epub 2017 Dec 21.

PMID:
29276101
8.

Complement C5a receptors C5L2 and C5aR in renal fibrosis.

Martin IV, Bohner A, Boor P, Shagdarsuren E, Raffetseder U, Lammert F, Floege J, Ostendorf T, Weber SN.

Am J Physiol Renal Physiol. 2018 Jan 1;314(1):F35-F46. doi: 10.1152/ajprenal.00060.2017. Epub 2017 Sep 13.

9.

YB-1 orchestrates onset and resolution of renal inflammation via IL10 gene regulation.

Wang J, Djudjaj S, Gibbert L, Lennartz V, Breitkopf DM, Rauen T, Hermert D, Martin IV, Boor P, Braun GS, Floege J, Ostendorf T, Raffetseder U.

J Cell Mol Med. 2017 Dec;21(12):3494-3505. doi: 10.1111/jcmm.13260. Epub 2017 Jun 30.

10.

Therapeutic nuclear shuttling of YB-1 reduces renal damage and fibrosis.

Wang J, Gibbert L, Djudjaj S, Alidousty C, Rauen T, Kunter U, Rembiak A, Enders D, Jankowski V, Braun GS, Floege J, Ostendorf T, Raffetseder U.

Kidney Int. 2016 Dec;90(6):1226-1237. doi: 10.1016/j.kint.2016.07.008. Epub 2016 Aug 31.

PMID:
27591085
11.

Cold Shock Proteins Mediate GN with Mesangioproliferation.

Zhu C, Sauter E, Schreiter A, van Roeyen CR, Ostendorf T, Floege J, Gembardt F, Hugo CP, Isermann B, Lindquist JA, Mertens PR.

J Am Soc Nephrol. 2016 Dec;27(12):3678-3689. Epub 2016 May 5.

12.

CXCR5 is critically involved in progression of lupus through regulation of B cell and double-negative T cell trafficking.

Wiener A, Schippers A, Wagner N, Tacke F, Ostendorf T, Honke N, Tenbrock K, Ohl K.

Clin Exp Immunol. 2016 Jul;185(1):22-32. doi: 10.1111/cei.12791. Epub 2016 Apr 18.

13.

Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74.

Djudjaj S, Lue H, Rong S, Papasotiriou M, Klinkhammer BM, Zok S, Klaener O, Braun GS, Lindenmeyer MT, Cohen CD, Bucala R, Tittel AP, Kurts C, Moeller MJ, Floege J, Ostendorf T, Bernhagen J, Boor P.

J Am Soc Nephrol. 2016 Jun;27(6):1650-64. doi: 10.1681/ASN.2015020149. Epub 2015 Oct 9.

14.

Anti-interleukin-6 therapy through application of a monogenic protein inhibitor via gene delivery.

Görtz D, Braun GS, Maruta Y, Djudjaj S, van Roeyen CR, Martin IV, Küster A, Schmitz-Van de Leur H, Scheller J, Ostendorf T, Floege J, Müller-Newen G.

Sci Rep. 2015 Oct 1;5:14685. doi: 10.1038/srep14685.

15.

Platelet-derived growth factors (PDGFs) in glomerular and tubulointerstitial fibrosis.

Ostendorf T, Boor P, van Roeyen CR, Floege J.

Kidney Int Suppl (2011). 2014 Nov;4(1):65-69. Review.

16.

Role of platelet-derived growth factor-CC in capillary rarefaction in renal fibrosis.

Boor P, Bábíčková J, Steegh F, Hautvast P, Martin IV, Djudjaj S, Nakagawa T, Ehling J, Gremse F, Bücher E, Eriksson U, van Roeyen CR, Eitner F, Lammers T, Floege J, Peutz-Kootstra CJ, Ostendorf T.

Am J Pathol. 2015 Aug;185(8):2132-42. doi: 10.1016/j.ajpath.2015.04.022.

PMID:
26216283
17.

IL-6 Trans-Signaling Drives Murine Crescentic GN.

Braun GS, Nagayama Y, Maruta Y, Heymann F, van Roeyen CR, Klinkhammer BM, Boor P, Villa L, Salant DJ, Raffetseder U, Rose-John S, Ostendorf T, Floege J.

J Am Soc Nephrol. 2016 Jan;27(1):132-42. doi: 10.1681/ASN.2014111147. Epub 2015 Jun 3.

18.

Common histological patterns in glomerular epithelial cells in secondary focal segmental glomerulosclerosis.

Kuppe C, Gröne HJ, Ostendorf T, van Kuppevelt TH, Boor P, Floege J, Smeets B, Moeller MJ.

Kidney Int. 2015 Nov;88(5):990-8. doi: 10.1038/ki.2015.116. Epub 2015 Apr 8.

PMID:
25853334
19.

AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury.

Challagundla M, Koch JC, Ribas VT, Michel U, Kügler S, Ostendorf T, Bradke F, Müller HW, Bähr M, Lingor P.

J Neurochem. 2015 Jul;134(2):261-75. doi: 10.1111/jnc.13102. Epub 2015 Apr 13.

20.

Diffusion-weighted MRI does not reflect kidney fibrosis in a rat model of fibrosis.

Boor P, Perkuhn M, Weibrecht M, Zok S, Martin IV, Gieseke J, Schoth F, Ostendorf T, Kuhl C, Floege J.

J Magn Reson Imaging. 2015 Oct;42(4):990-8. doi: 10.1002/jmri.24853. Epub 2015 Jan 28.

PMID:
25630829
21.

Detection of activated parietal epithelial cells on the glomerular tuft distinguishes early focal segmental glomerulosclerosis from minimal change disease.

Smeets B, Stucker F, Wetzels J, Brocheriou I, Ronco P, Gröne HJ, D'Agati V, Fogo AB, van Kuppevelt TH, Fischer HP, Boor P, Floege J, Ostendorf T, Moeller MJ.

Am J Pathol. 2014 Dec;184(12):3239-48. doi: 10.1016/j.ajpath.2014.08.007. Epub 2014 Oct 7.

22.

Calcineurin-mediated YB-1 dephosphorylation regulates CCL5 expression during monocyte differentiation.

Alidousty C, Rauen T, Hanssen L, Wang Q, Alampour-Rajabi S, Mertens PR, Bernhagen J, Floege J, Ostendorf T, Raffetseder U.

J Biol Chem. 2014 Aug 1;289(31):21401-12. doi: 10.1074/jbc.M114.562991. Epub 2014 Jun 19.

23.

Gp130-dependent signaling in the podocyte.

Nagayama Y, Braun GS, Jakobs CM, Maruta Y, van Roeyen CR, Klinkhammer BM, Boor P, Villa L, Raffetseder U, Trautwein C, Görtz D, Müller-Newen G, Ostendorf T, Floege J.

Am J Physiol Renal Physiol. 2014 Aug 1;307(3):F346-55. doi: 10.1152/ajprenal.00620.2013. Epub 2014 Jun 4.

24.

PDGF and the progression of renal disease.

Boor P, Ostendorf T, Floege J.

Nephrol Dial Transplant. 2014 Feb;29 Suppl 1:i45-i54. doi: 10.1093/ndt/gft273. Review.

PMID:
24493869
25.

YB-1 is an early and central mediator of bacterial and sterile inflammation in vivo.

Hanssen L, Alidousty C, Djudjaj S, Frye BC, Rauen T, Boor P, Mertens PR, van Roeyen CR, Tacke F, Heymann F, Tittel AP, Koch A, Floege J, Ostendorf T, Raffetseder U.

J Immunol. 2013 Sep 1;191(5):2604-13. doi: 10.4049/jimmunol.1300416. Epub 2013 Jul 19.

26.

Confirming aortic aneurysm after cardiac arrest--challenge of the unknown?

Struck MF, Ostendorf T.

Resuscitation. 2013 Mar;84(3):e55-6. doi: 10.1016/j.resuscitation.2012.12.013. Epub 2012 Dec 22. No abstract available.

PMID:
23266534
27.

Growth arrest-specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation.

van Roeyen CR, Zok S, Pruessmeyer J, Boor P, Nagayama Y, Fleckenstein S, Cohen CD, Eitner F, Gröne HJ, Ostendorf T, Ludwig A, Floege J.

Kidney Int. 2013 Feb;83(2):251-63. doi: 10.1038/ki.2012.400. Epub 2012 Dec 19.

28.

Biological responses to PDGF-AA versus PDGF-CC in renal fibroblasts.

Seikrit C, Henkel C, van Roeyen CR, Bokemeyer D, Eitner F, Martin IV, Boor P, Knüchel R, Meyer HE, Müller-Newen G, Eriksson U, Floege J, Ostendorf T.

Nephrol Dial Transplant. 2013 Apr;28(4):889-900. doi: 10.1093/ndt/gfs509. Epub 2012 Dec 9.

PMID:
23229927
29.

Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms.

Villa L, Boor P, Konieczny A, Kunter U, van Roeyen CR, Denecke B, Gan L, Neusser MA, Cohen CD; ERCB Consortium;, Eitner F, Scholl T, Ostendorf T, Floege J.

J Pathol. 2013 Apr;229(5):672-84. doi: 10.1002/path.4151. Epub 2013 Mar 5.

PMID:
23192593
30.

Platelet-derived growth factor (PDGF)-C neutralization reveals differential roles of PDGF receptors in liver and kidney fibrosis.

Martin IV, Borkham-Kamphorst E, Zok S, van Roeyen CR, Eriksson U, Boor P, Hittatiya K, Fischer HP, Wasmuth HE, Weiskirchen R, Eitner F, Floege J, Ostendorf T.

Am J Pathol. 2013 Jan;182(1):107-17. doi: 10.1016/j.ajpath.2012.09.006. Epub 2012 Nov 7.

PMID:
23141925
31.

Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury.

Djudjaj S, Chatziantoniou C, Raffetseder U, Guerrot D, Dussaule JC, Boor P, Kerroch M, Hanssen L, Brandt S, Dittrich A, Ostendorf T, Floege J, Zhu C, Lindenmeyer M, Cohen CD, Mertens PR.

J Pathol. 2012 Nov;228(3):286-99. doi: 10.1002/path.4076. Epub 2012 Sep 7.

PMID:
22806125
32.

A novel, dual role of CCN3 in experimental glomerulonephritis: pro-angiogenic and antimesangioproliferative effects.

van Roeyen CR, Boor P, Borkham-Kamphorst E, Rong S, Kunter U, Martin IV, Kaitovic A, Fleckenstein S, Perbal B, Trautwein C, Weiskirchen R, Ostendorf T, Floege J.

Am J Pathol. 2012 May;180(5):1979-90. doi: 10.1016/j.ajpath.2012.01.031.

PMID:
22538190
33.

Subtotal ablation of parietal epithelial cells induces crescent formation.

Sicking EM, Fuss A, Uhlig S, Jirak P, Dijkman H, Wetzels J, Engel DR, Urzynicok T, Heidenreich S, Kriz W, Kurts C, Ostendorf T, Floege J, Smeets B, Moeller MJ.

J Am Soc Nephrol. 2012 Apr;23(4):629-40. doi: 10.1681/ASN.2011050449. Epub 2012 Jan 26.

34.

Role for CD74 and CXCR4 in clathrin-dependent endocytosis of the cytokine MIF.

Schwartz V, Krüttgen A, Weis J, Weber C, Ostendorf T, Lue H, Bernhagen J.

Eur J Cell Biol. 2012 Jun-Jul;91(6-7):435-49. doi: 10.1016/j.ejcb.2011.08.006. Epub 2011 Oct 19.

PMID:
22014447
35.

The platelet-derived growth factor system in renal disease: an emerging role of endogenous inhibitors.

van Roeyen CR, Ostendorf T, Floege J.

Eur J Cell Biol. 2012 Jun-Jul;91(6-7):542-51. doi: 10.1016/j.ejcb.2011.07.003. Epub 2011 Aug 27. Review.

PMID:
21872965
36.

Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D.

van Roeyen CR, Eitner F, Boor P, Moeller MJ, Raffetseder U, Hanssen L, Bücher E, Villa L, Banas MC, Hudkins KL, Alpers CE, Ostendorf T, Floege J.

Kidney Int. 2011 Dec;80(12):1292-305. doi: 10.1038/ki.2011.278. Epub 2011 Aug 24.

37.

The peroxisome proliferator-activated receptor-α agonist, BAY PP1, attenuates renal fibrosis in rats.

Boor P, Celec P, Martin IV, Villa L, Hodosy J, Klenovicsová K, Esposito C, Schäfer S, Albrecht-Küpper B, Ostendorf T, Heidland A, Šebeková K.

Kidney Int. 2011 Dec;80(11):1182-97. doi: 10.1038/ki.2011.254. Epub 2011 Aug 3.

38.

Y-box binding protein-1 mediates profibrotic effects of calcineurin inhibitors in the kidney.

Hanssen L, Frye BC, Ostendorf T, Alidousty C, Djudjaj S, Boor P, Rauen T, Floege J, Mertens PR, Raffetseder U.

J Immunol. 2011 Jul 1;187(1):298-308. doi: 10.4049/jimmunol.1100382. Epub 2011 May 23.

39.

The PDGF family in renal fibrosis.

Ostendorf T, Eitner F, Floege J.

Pediatr Nephrol. 2012 Jul;27(7):1041-50. doi: 10.1007/s00467-011-1892-z. Epub 2011 May 21. Review.

PMID:
21597969
40.

Hepatocyte growth factor protects retinal ganglion cells by increasing neuronal survival and axonal regeneration in vitro and in vivo.

Tönges L, Ostendorf T, Lamballe F, Genestine M, Dono R, Koch JC, Bähr M, Maina F, Lingor P.

J Neurochem. 2011 Jun;117(5):892-903. doi: 10.1111/j.1471-4159.2011.07257.x. Epub 2011 Apr 26.

41.

Effects and mechanisms of angiotensin II receptor blockade with telmisartan in a normotensive model of mesangioproliferative nephritis.

Villa L, Boor P, Konieczny A, Kunter U, van Roeyen CR, Denecke B, Gan L, Kupper MB, Hoffmann K, Eitner F, Ostendorf T, Floege J.

Nephrol Dial Transplant. 2011 Oct;26(10):3131-43. doi: 10.1093/ndt/gfr096. Epub 2011 Mar 17.

PMID:
21414972
42.

Extracellular YB-1 blockade in experimental nephritis upregulates Notch-3 receptor expression and signaling.

Raffetseder U, Rauen T, Boor P, Ostendorf T, Hanssen L, Floege J, En-Nia A, Djudjaj S, Frye BC, Mertens PR.

Nephron Exp Nephrol. 2011;118(4):e100-8. doi: 10.1159/000324209. Epub 2011 Mar 2.

PMID:
21372592
43.

Renal fibrosis: novel insights into mechanisms and therapeutic targets.

Boor P, Ostendorf T, Floege J.

Nat Rev Nephrol. 2010 Nov;6(11):643-56. doi: 10.1038/nrneph.2010.120. Epub 2010 Sep 14. Review.

PMID:
20838416
44.

Endothelin signaling via guanine exchange factor C3G in renal glomerular mesangial cells.

Rufanova VA, Alexanian A, Ostendorf T, Bokemeyer D, Prosser S, Miller B, Sorokin A.

Can J Physiol Pharmacol. 2010 Aug;88(8):808-16. doi: 10.1139/Y10-056.

45.

PDGF-C mediates glomerular capillary repair.

Boor P, van Roeyen CR, Kunter U, Villa L, Bücher E, Hohenstein B, Hugo CP, Eriksson U, Satchell SC, Mathieson PW, Eitner F, Floege J, Ostendorf T.

Am J Pathol. 2010 Jul;177(1):58-69. doi: 10.2353/ajpath.2010.091008. Epub 2010 May 20.

46.

Acute axonal degeneration in vivo is attenuated by inhibition of autophagy in a calcium-dependent manner.

Koch JC, Knöferle J, Tönges L, Ostendorf T, Bähr M, Lingor P.

Autophagy. 2010 Jul;6(5):658-9. doi: 10.4161/auto.6.5.12188. Epub 2010 Jul 1.

PMID:
20458173
47.

Mechanisms of acute axonal degeneration in the optic nerve in vivo.

Knöferle J, Koch JC, Ostendorf T, Michel U, Planchamp V, Vutova P, Tönges L, Stadelmann C, Brück W, Bähr M, Lingor P.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6064-9. doi: 10.1073/pnas.0909794107. Epub 2010 Mar 15.

48.

Regular moderate exercise reduces advanced glycation and ameliorates early diabetic nephropathy in obese Zucker rats.

Boor P, Celec P, Behuliak M, Grancic P, Kebis A, Kukan M, Pronayová N, Liptaj T, Ostendorf T, Sebeková K.

Metabolism. 2009 Nov;58(11):1669-77. doi: 10.1016/j.metabol.2009.05.025. Epub 2009 Jul 15.

PMID:
19608208
49.

Patients with IgA nephropathy exhibit high systemic PDGF-DD levels.

Boor P, Eitner F, Cohen CD, Lindenmeyer MT; ERCB-Consortium, Mertens PR, Ostendorf T, Floege J.

Nephrol Dial Transplant. 2009 Sep;24(9):2755-62. doi: 10.1093/ndt/gfp152. Epub 2009 Apr 8.

50.

BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity.

Planchamp V, Bermel C, Tönges L, Ostendorf T, Kügler S, Reed JC, Kermer P, Bähr M, Lingor P.

Brain. 2008 Oct;131(Pt 10):2606-19. doi: 10.1093/brain/awn196. Epub 2008 Aug 29.

PMID:
18757464

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