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Items: 21


The serine protease homolog CLIPA14 modulates the intensity of the immune response in the mosquito Anopheles gambiae.

Nakhleh J, Christophides GK, Osta MA.

J Biol Chem. 2017 Nov 3;292(44):18217-18226. doi: 10.1074/jbc.M117.797787. Epub 2017 Sep 19.


Functional Interaction between Apolipophorins and Complement Regulate the Mosquito Immune Response to Systemic Infections.

Kamareddine L, Nakhleh J, Osta MA.

J Innate Immun. 2016;8(3):314-26. doi: 10.1159/000443883. Epub 2016 Mar 8.


A serine protease homolog negatively regulates TEP1 consumption in systemic infections of the malaria vector Anopheles gambiae.

Yassine H, Kamareddine L, Chamat S, Christophides GK, Osta MA.

J Innate Immun. 2014;6(6):806-18. doi: 10.1159/000363296. Epub 2014 Jul 8.


The CLIP-domain serine protease homolog SPCLIP1 regulates complement recruitment to microbial surfaces in the malaria mosquito Anopheles gambiae.

Povelones M, Bhagavatula L, Yassine H, Tan LA, Upton LM, Osta MA, Christophides GK.

PLoS Pathog. 2013;9(9):e1003623. doi: 10.1371/journal.ppat.1003623. Epub 2013 Sep 5.


The mosquito melanization response is implicated in defense against the entomopathogenic fungus Beauveria bassiana.

Yassine H, Kamareddine L, Osta MA.

PLoS Pathog. 2012;8(11):e1003029. doi: 10.1371/journal.ppat.1003029. Epub 2012 Nov 15.


Aedes albopictus in Lebanon, a potential risk of arboviruses outbreak.

Haddad N, Mousson L, Vazeille M, Chamat S, Tayeh J, Osta MA, Failloux AB.

BMC Infect Dis. 2012 Nov 14;12:300. doi: 10.1186/1471-2334-12-300.


Insecticide resistance to organophosphates in Culex pipiens complex from Lebanon.

Osta MA, Rizk ZJ, Labbé P, Weill M, Knio K.

Parasit Vectors. 2012 Jul 3;5:132. doi: 10.1186/1756-3305-5-132.


Delayed phosphorylation of classical protein kinase C (PKC) substrates requires PKC internalization and formation of the pericentrion in a phospholipase D (PLD)-dependent manner.

El-Osta MA, Idkowiak-Baldys J, Hannun YA.

J Biol Chem. 2011 Jun 3;286(22):19340-53. doi: 10.1074/jbc.M110.152330. Epub 2011 Apr 8.


Nicotinic acetylcholine receptor gene expression is altered in burn patients.

Osta WA, El-Osta MA, Pezhman EA, Raad RA, Ferguson K, McKelvey GM, Marsh HM, White M, Perov S.

Anesth Analg. 2010 May 1;110(5):1355-9. doi: 10.1213/ANE.0b013e3181d41512. Epub 2010 Mar 19.


Anopheles gambiae innate immunity.

Yassine H, Osta MA.

Cell Microbiol. 2010 Jan;12(1):1-9. doi: 10.1111/j.1462-5822.2009.01388.x. Epub 2009 Oct 5. Review.


Two C-type lectins cooperate to defend Anopheles gambiae against Gram-negative bacteria.

Schnitger AK, Yassine H, Kafatos FC, Osta MA.

J Biol Chem. 2009 Jun 26;284(26):17616-24. doi: 10.1074/jbc.M808298200. Epub 2009 Apr 20.


Characterization of new mutations in the 5'-flanking region of the familial Mediterranean fever gene.

Notarnicola C, Boizet-Bonhoure B, de Santa Barbara P, Osta MA, Cattan D, Touitou I.

Genes Immun. 2009 Apr;10(3):273-9. doi: 10.1038/gene.2009.8. Epub 2009 Mar 5.


Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes.

Waterhouse RM, Kriventseva EV, Meister S, Xi Z, Alvarez KS, Bartholomay LC, Barillas-Mury C, Bian G, Blandin S, Christensen BM, Dong Y, Jiang H, Kanost MR, Koutsos AC, Levashina EA, Li J, Ligoxygakis P, Maccallum RM, Mayhew GF, Mendes A, Michel K, Osta MA, Paskewitz S, Shin SW, Vlachou D, Wang L, Wei W, Zheng L, Zou Z, Severson DW, Raikhel AS, Kafatos FC, Dimopoulos G, Zdobnov EM, Christophides GK.

Science. 2007 Jun 22;316(5832):1738-43.


The melanization reaction is not required for survival of Anopheles gambiae mosquitoes after bacterial infections.

Schnitger AK, Kafatos FC, Osta MA.

J Biol Chem. 2007 Jul 27;282(30):21884-8. Epub 2007 May 30.


Anopheles and Plasmodium: from laboratory models to natural systems in the field.

Cohuet A, Osta MA, Morlais I, Awono-Ambene PH, Michel K, Simard F, Christophides GK, Fontenille D, Kafatos FC.

EMBO Rep. 2006 Dec;7(12):1285-9. Epub 2006 Nov 10.


A genetic module regulates the melanization response of Anopheles to Plasmodium.

Volz J, Müller HM, Zdanowicz A, Kafatos FC, Osta MA.

Cell Microbiol. 2006 Sep;8(9):1392-405.


The roles of two clip domain serine proteases in innate immune responses of the malaria vector Anopheles gambiae.

Volz J, Osta MA, Kafatos FC, Müller HM.

J Biol Chem. 2005 Dec 2;280(48):40161-8. Epub 2005 Sep 27.


Innate immunity in the malaria vector Anopheles gambiae: comparative and functional genomics.

Osta MA, Christophides GK, Vlachou D, Kafatos FC.

J Exp Biol. 2004 Jul;207(Pt 15):2551-63. Review.


Effects of mosquito genes on Plasmodium development.

Osta MA, Christophides GK, Kafatos FC.

Science. 2004 Mar 26;303(5666):2030-2.


Immunity-related genes and gene families in Anopheles gambiae.

Christophides GK, Zdobnov E, Barillas-Mury C, Birney E, Blandin S, Blass C, Brey PT, Collins FH, Danielli A, Dimopoulos G, Hetru C, Hoa NT, Hoffmann JA, Kanzok SM, Letunic I, Levashina EA, Loukeris TG, Lycett G, Meister S, Michel K, Moita LF, Müller HM, Osta MA, Paskewitz SM, Reichhart JM, Rzhetsky A, Troxler L, Vernick KD, Vlachou D, Volz J, von Mering C, Xu J, Zheng L, Bork P, Kafatos FC.

Science. 2002 Oct 4;298(5591):159-65.

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