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Items: 1 to 50 of 107

1.

Differential Effects of Integrin αv Knockdown and Cilengitide on Sensitization of Triple-Negative Breast Cancer and Melanoma Cells to Microtubule Poisons.

Stojanović N, Dekanić A, Paradžik M, Majhen D, Ferenčak K, Ruščić J, Bardak I, Supina C, Tomicic MT, Christmann M, Osmak M, Ambriović-Ristov A.

Mol Pharmacol. 2018 Dec;94(6):1334-1351. doi: 10.1124/mol.118.113027. Epub 2018 Sep 27.

PMID:
30262596
2.

Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis.

Vajs J, Proud C, Brozovic A, Gazvoda M, Lloyd A, Roper DI, Osmak M, Košmrlj J, Dowson CG.

Eur J Med Chem. 2017 Feb 15;127:223-234. doi: 10.1016/j.ejmech.2016.12.060. Epub 2016 Dec 31.

PMID:
28063354
3.

Discovery of 'click' 1,2,3-triazolium salts as potential anticancer drugs.

Steiner I, Stojanovic N, Bolje A, Brozovic A, Polancec D, Ambriovic-Ristov A, Stojkovic MR, Piantanida I, Eljuga D, Kosmrlj J, Osmak M.

Radiol Oncol. 2016 Jul 19;50(3):280-8. doi: 10.1515/raon-2016-0027. eCollection 2016 Sep 1.

4.

Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair.

Christmann M, Diesler K, Majhen D, Steigerwald C, Berte N, Freund H, Stojanović N, Kaina B, Osmak M, Ambriović-Ristov A, Tomicic MT.

Oncotarget. 2017 Apr 25;8(17):27754-27771. doi: 10.18632/oncotarget.10897.

5.

Integrin αvβ3 expression in tongue squamous carcinoma cells Cal27 confers anticancer drug resistance through loss of pSrc(Y418).

Stojanović N, Brozovic A, Majhen D, Bosnar MH, Fritz G, Osmak M, Ambriović-Ristov A.

Biochim Biophys Acta. 2016 Aug;1863(8):1969-78. doi: 10.1016/j.bbamcr.2016.04.019. Epub 2016 Apr 21.

6.

The 1,3-diaryltriazenido(p-cymene)ruthenium(II) complexes with a high in vitro anticancer activity.

Vajs J, Steiner I, Brozovic A, Pevec A, Ambriović-Ristov A, Matković M, Piantanida I, Urankar D, Osmak M, Košmrlj J.

J Inorg Biochem. 2015 Dec;153:42-48. doi: 10.1016/j.jinorgbio.2015.09.005. Epub 2015 Sep 14.

PMID:
26409161
7.
8.

Antitumour action on human glioblastoma A1235 cells through cooperation of bee venom and cisplatin.

Gajski G, Čimbora-Zovko T, Rak S, Osmak M, Garaj-Vrhovac V.

Cytotechnology. 2016 Aug;68(4):1197-205. doi: 10.1007/s10616-015-9879-4. Epub 2015 Apr 28.

9.

Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury.

Krüger K, Thomale J, Stojanović N, Osmak M, Henninger C, Bormann S, Fritz G.

Biochim Biophys Acta. 2015 Mar;1853(3):685-98. doi: 10.1016/j.bbamcr.2014.12.033. Epub 2015 Jan 4.

10.

Combined antitumor effects of bee venom and cisplatin on human cervical and laryngeal carcinoma cells and their drug resistant sublines.

Gajski G, Čimbora-Zovko T, Rak S, Rožman M, Osmak M, Garaj-Vrhovac V.

J Appl Toxicol. 2014 Dec;34(12):1332-41.

PMID:
25493319
11.

Combining [arene-Ru] with azocarboxamide to generate a complex with cytotoxic properties.

Sommer MG, Kureljak P, Urankar D, Schweinfurth D, Stojanović N, Bubrin M, Gazvoda M, Osmak M, Sarkar B, Košmrlj J.

Chemistry. 2014 Dec 22;20(52):17296-9. doi: 10.1002/chem.201404448. Epub 2014 Nov 5.

PMID:
25376425
12.

FTIR spectroscopy reveals lipid droplets in drug resistant laryngeal carcinoma cells through detection of increased ester vibrational bands intensity.

Rak S, De Zan T, Stefulj J, Kosović M, Gamulin O, Osmak M.

Analyst. 2014 Jul 7;139(13):3407-15. doi: 10.1039/c4an00412d.

PMID:
24834449
13.

Increased adenovirus Type 5 mediated transgene expression due to RhoB down-regulation.

Majhen D, Stojanović N, Vukić D, Pichon C, Leduc C, Osmak M, Ambriović-Ristov A.

PLoS One. 2014 Jan 22;9(1):e86698. doi: 10.1371/journal.pone.0086698. eCollection 2014.

14.

Synthesis and biological activity of new diazenedicarboxamides as potential anticancer agents.

Vajs J, Soviček S, Kureljak P, Stojanović N, Steiner I, Eljuga D, Urankar D, Kočevar M, Košmrlj J, Polanc S, Osmak M.

Acta Chim Slov. 2013;60(4):842-52.

PMID:
24362988
15.

3-Acetyl-bis(2-chloro-4-nitrophenyl)triazene is a potent antitumor agent that induces oxidative stress and independently activates the stress-activated protein kinase/c-Jun NH2-terminal kinase pathway.

Brozovic A, Stojanović N, Ambriović-Ristov A, Brozović Krijan A, Polanc S, Osmak M.

Anticancer Drugs. 2014 Mar;25(3):289-95. doi: 10.1097/CAD.0000000000000060.

PMID:
24322543
16.

Endoplasmic reticulum stress is involved in the response of human laryngeal carcinoma cells to Carboplatin but is absent in Carboplatin-resistant cells.

Brozovic A, Vuković L, Polančac DS, Arany I, Köberle B, Fritz G, Fiket Z, Majhen D, Ambriović-Ristov A, Osmak M.

PLoS One. 2013 Sep 23;8(9):e76397. doi: 10.1371/journal.pone.0076397. eCollection 2013.

17.

Design and evaluation of biological activity of diazenecarboxamide-extended cisplatin and carboplatin analogues.

Stojanovic N, Urankar D, Brozović A, Ambriović-Ristov A, Osmak M, Kosmrlj J.

Acta Chim Slov. 2013;60(2):368-74.

PMID:
23878941
18.

Accurate models for P-gp drug recognition induced from a cancer cell line cytotoxicity screen.

Levatić J, Ćurak J, Kralj M, Šmuc T, Osmak M, Supek F.

J Med Chem. 2013 Jul 25;56(14):5691-708. doi: 10.1021/jm400328s. Epub 2013 Jul 8.

PMID:
23772653
19.

Carboplatin resistant human laryngeal carcinoma cells are cross resistant to curcumin due to reduced curcumin accumulation.

Rak S, Cimbora-Zovko T, Gajski G, Dubravčić K, Domijan AM, Delaš I, Garaj-Vrhovac V, Batinić D, Sorić J, Osmak M.

Toxicol In Vitro. 2013 Mar;27(2):523-32. doi: 10.1016/j.tiv.2012.11.003. Epub 2012 Nov 9.

PMID:
23147641
20.

Statins and cancer: current and future prospects.

Osmak M.

Cancer Lett. 2012 Nov 1;324(1):1-12. doi: 10.1016/j.canlet.2012.04.011. Epub 2012 Apr 24. Review.

PMID:
22542807
21.

Increased expression of the coxsackie and adenovirus receptor downregulates αvβ3 and αvβ5 integrin expression and reduces cell adhesion and migration.

Majhen D, Stojanović N, Špeljko T, Brozovic A, De Zan T, Osmak M, Ambriović-Ristov A.

Life Sci. 2011 Aug 15;89(7-8):241-9. doi: 10.1016/j.lfs.2011.06.009. Epub 2011 Jun 22.

PMID:
21712047
22.

Genotoxic effects of green tea extract on human laryngeal carcinoma cells in vitro.

Durgo K, Kostić S, Gradiški K, Komes D, Osmak M, Franekić J.

Arh Hig Rada Toksikol. 2011 Jun;62(2):139-46. doi: 10.2478/10004-1254-62-2011-2105.

PMID:
21705301
23.

Synthesis and biological evaluation of 4-nitro-substituted 1,3-diaryltriazenes as a novel class of potent antitumor agents.

Cimbora-Zovko T, Brozovic A, Piantanida I, Fritz G, Virag A, Alič B, Majce V, Kočevar M, Polanc S, Osmak M.

Eur J Med Chem. 2011 Jul;46(7):2971-83. doi: 10.1016/j.ejmech.2011.04.024. Epub 2011 Apr 23.

PMID:
21550697
24.

Late activation of stress-activated protein kinases/c-Jun N-terminal kinases triggered by cisplatin-induced DNA damage in repair-defective cells.

Helbig L, Damrot J, Hülsenbeck J, Köberle B, Brozovic A, Osmak M, Fiket Z, Kaina B, Fritz G.

J Biol Chem. 2011 Apr 15;286(15):12991-3001. doi: 10.1074/jbc.M110.190645. Epub 2011 Feb 15.

25.

Vincristine-resistant human laryngeal carcinoma cells demonstrate increased Rous sarcoma virus promoter activity.

Majhen D, Brozovic A, Buger T, Gabrilovac J, Osmak M, Ambriović-Ristov A.

Life Sci. 2010 Oct 9;87(15-16):468-74. doi: 10.1016/j.lfs.2010.08.012. Epub 2010 Sep 17.

PMID:
20837033
26.

Pyrazolone-fused combretastatins and their precursors: synthesis, cytotoxicity, antitubulin activity and molecular modeling studies.

Burja B, Cimbora-Zovko T, Tomić S, Jelusić T, Kocevar M, Polanc S, Osmak M.

Bioorg Med Chem. 2010 Apr 1;18(7):2375-87. doi: 10.1016/j.bmc.2010.03.006. Epub 2010 Mar 10.

PMID:
20338766
27.

Downregulation of RhoB GTPase confers resistance to cisplatin in human laryngeal carcinoma cells.

Cimbora-Zovko T, Fritz G, Mikac N, Osmak M.

Cancer Lett. 2010 Sep 28;295(2):182-90. doi: 10.1016/j.canlet.2010.02.025. Epub 2010 Mar 19.

PMID:
20303648
28.

The relationship between cisplatin-induced reactive oxygen species, glutathione, and BCL-2 and resistance to cisplatin.

Brozovic A, Ambriović-Ristov A, Osmak M.

Crit Rev Toxicol. 2010 Apr;40(4):347-59. doi: 10.3109/10408441003601836. Review.

PMID:
20163198
29.

Cisplatin sensitivity is related to late DNA damage processing and checkpoint control rather than to the early DNA damage response.

Brozovic A, Damrot J, Tsaryk R, Helbig L, Nikolova T, Hartig C, Osmak M, Roos WP, Kaina B, Fritz G.

Mutat Res. 2009 Nov 2;670(1-2):32-41. doi: 10.1016/j.mrfmmm.2009.07.002. Epub 2009 Jul 16.

PMID:
19616017
30.

Differential role of alpha(v)beta(3) and alpha(v)beta(5) integrins in internalization and transduction efficacies of wild type and RGD4C fiber-modified adenoviruses.

Majhen D, Nemet J, Richardson J, Gabrilovac J, Hajsig M, Osmak M, Eloit M, Ambriović-Ristov A.

Virus Res. 2009 Jan;139(1):64-73. doi: 10.1016/j.virusres.2008.10.004. Epub 2008 Dec 2.

PMID:
19013487
31.

alpha(v)beta(3) Integrin-mediated drug resistance in human laryngeal carcinoma cells is caused by glutathione-dependent elimination of drug-induced reactive oxidative species.

Brozovic A, Majhen D, Roje V, Mikac N, Jakopec S, Fritz G, Osmak M, Ambriovic-Ristov A.

Mol Pharmacol. 2008 Jul;74(1):298-306. doi: 10.1124/mol.107.043836. Epub 2008 Apr 25.

32.

Lithium effect on glutamate induced damage in glioblastoma cells.

Jakopec S, Karlović D, Dubravcić K, Batinić D, Sorić J, Brozović A, Buljan D, Osmak M.

Coll Antropol. 2008 Jan;32 Suppl 1:87-91.

PMID:
18405064
33.

Total tissue lactate dehydrogenase activity in endometrial carcinoma.

Simaga S, Abramić M, Osmak M, Babić D, Ilić-Forko J.

Int J Gynecol Cancer. 2008 Nov-Dec;18(6):1272-8. doi: 10.1111/j.1525-1438.2008.01196.x. Epub 2008 Feb 15.

PMID:
18284453
34.

Selective cytotoxicity of diazenecarboxamides towards human leukemic cell lines.

Martin-Kleiner I, Bombek S, Kosmrlj J, Cupić B, Cimbora-Zovko T, Jakopec S, Polanc S, Osmak M, Gabrilovac J.

Toxicol In Vitro. 2007 Dec;21(8):1453-9. Epub 2007 Jun 28.

PMID:
17686609
35.

Altered cell-cell adhesion in cisplatin-resistant human carcinoma cells: a link between beta-catenin/plakoglobin ratio and cisplatin resistance.

Cimbora-Zovko T, Ambriović-Ristov A, Loncarek J, Osmak M.

Eur J Pharmacol. 2007 Mar 8;558(1-3):27-36. Epub 2006 Dec 12.

PMID:
17234182
36.

Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance.

Brozovic A, Osmak M.

Cancer Lett. 2007 Jun 18;251(1):1-16. Epub 2006 Nov 27. Review.

PMID:
17125914
37.

Lithium increases expression of p21(WAF/Cip1) and survivin in human glioblastoma cells.

Karlovic D, Jakopec S, Dubravcic K, Batinic D, Buljan D, Osmak M.

Cell Biol Toxicol. 2007 Mar;23(2):83-90. Epub 2006 Nov 10.

PMID:
17103031
38.

Relevance of drug uptake and efflux for cisplatin sensitivity of tumor cells.

Zisowsky J, Koegel S, Leyers S, Devarakonda K, Kassack MU, Osmak M, Jaehde U.

Biochem Pharmacol. 2007 Jan 15;73(2):298-307. Epub 2006 Oct 10.

PMID:
17097621
39.

Structurally similar diazenes exhibit significantly different biological activity.

Jakopec S, Dubravcic K, Brozovic A, Polanc S, Osmak M.

Cell Biol Toxicol. 2006 Jan;22(1):61-71.

PMID:
16463020
40.

Diazene JK-279 induces apoptosis-like cell death in human cervical carcinoma cells.

Jakopec S, Dubravcic K, Polanc S, Kosmrlj J, Osmak M.

Toxicol In Vitro. 2006 Mar;20(2):217-26. Epub 2005 Aug 2.

PMID:
16061352
41.

Quantitative biochemical analysis of lactate dehydrogenase in human ovarian tissues: correlation with tumor grade.

Simaga S, Osmak M, Babic D, Sprem M, Vukelic B, Abramic M.

Int J Gynecol Cancer. 2005 May-Jun;15(3):438-44.

PMID:
15882167
42.

The cytotoxicity of RoekoSeal and AH plus compared during different setting periods.

Miletić I, Devcić N, Anić I, Borcić J, Karlović Z, Osmak M.

J Endod. 2005 Apr;31(4):307-9.

PMID:
15793391
43.

Long-term activation of SAPK/JNK, p38 kinase and fas-L expression by cisplatin is attenuated in human carcinoma cells that acquired drug resistance.

Brozovic A, Fritz G, Christmann M, Zisowsky J, Jaehde U, Osmak M, Kaina B.

Int J Cancer. 2004 Dec 20;112(6):974-85.

45.

Highly reactive cysteine residues are part of the substrate binding site of mammalian dipeptidyl peptidases III.

Abramić M, Simaga S, Osmak M, Cicin-Sain L, Vukelić B, Vlahovicek K, Dolovcak L.

Int J Biochem Cell Biol. 2004 Mar;36(3):434-46.

PMID:
14687922
46.

Tumor cytosol dipeptidyl peptidase III activity is increased with histological aggressiveness of ovarian primary carcinomas.

Simaga S, Babić D, Osmak M, Sprem M, Abramić M.

Gynecol Oncol. 2003 Oct;91(1):194-200.

PMID:
14529681
47.

Examination of cytotoxicity and mutagenicity of AH26 and AH Plus sealers.

Miletić I, Jukić S, Anić I, Zeljezić D, Garaj-Vrhovac V, Osmak M.

Int Endod J. 2003 May;36(5):330-5.

PMID:
12752646
48.
49.

Diazenecarboxamide UP-91, a potential anticancer agent, acts by reducing cellular glutathione content.

Moskatelo D, Polanc S, Kosmrlj J, Vuković L, Osmak M.

Pharmacol Toxicol. 2002 Nov;91(5):258-63.

PMID:
12570033
50.

Serotonin and apoptosis: studies on rat lymphocytes.

Stefulj J, Jakopec S, Osmak M, Jernej B.

Neuroimmunomodulation. 2002-2003;10(3):132-3.

PMID:
12481152

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