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Items: 1 to 50 of 58

1.

Production and purification of chimeric HBc virus-like particles carrying influenza virus LAH domain as vaccine candidates.

Kazaks A, Lu IN, Farinelle S, Ramirez A, Crescente V, Blaha B, Ogonah O, Mukhopadhyay T, de Obanos MP, Krimer A, Akopjana I, Bogans J, Ose V, Kirsteina A, Kazaka T, Stonehouse NJ, Rowlands DJ, Muller CP, Tars K, Rosenberg WM.

BMC Biotechnol. 2017 Nov 10;17(1):79. doi: 10.1186/s12896-017-0396-8.

2.

The True Story and Advantages of RNA Phage Capsids as Nanotools.

Pumpens P, Renhofa R, Dishlers A, Kozlovska T, Ose V, Pushko P, Tars K, Grens E, Bachmann MF.

Intervirology. 2016;59(2):74-110. doi: 10.1159/000449503. Epub 2016 Nov 10. Review.

3.

The Hepatitis B Virus Core Variants that Expose Foreign C-Terminal Insertions on the Outer Surface of Virus-Like Particles.

Dishlers A, Skrastina D, Renhofa R, Petrovskis I, Ose V, Lieknina I, Jansons J, Pumpens P, Sominskaya I.

Mol Biotechnol. 2015 Dec;57(11-12):1038-49. doi: 10.1007/s12033-015-9895-9.

4.

Potato Virus M-Like Nanoparticles: Construction and Characterization.

Kalnciema I, Balke I, Skrastina D, Ose V, Zeltins A.

Mol Biotechnol. 2015 Dec;57(11-12):982-92. doi: 10.1007/s12033-015-9891-0.

PMID:
26346833
5.

Preparation by alkaline treatment and detailed characterisation of empty hepatitis B virus core particles for vaccine and gene therapy applications.

Strods A, Ose V, Bogans J, Cielens I, Kalnins G, Radovica I, Kazaks A, Pumpens P, Renhofa R.

Sci Rep. 2015 Jun 26;5:11639. doi: 10.1038/srep11639.

6.

Silica nanoparticles as the adjuvant for the immunisation of mice using hepatitis B core virus-like particles.

Skrastina D, Petrovskis I, Lieknina I, Bogans J, Renhofa R, Ose V, Dishlers A, Dekhtyar Y, Pumpens P.

PLoS One. 2014 Dec 1;9(12):e114006. doi: 10.1371/journal.pone.0114006. eCollection 2014.

7.

Mosaic RNA phage VLPs carrying domain III of the West Nile virus E protein.

Cielens I, Jackevica L, Strods A, Kazaks A, Ose V, Bogans J, Pumpens P, Renhofa R.

Mol Biotechnol. 2014 May;56(5):459-69. doi: 10.1007/s12033-014-9743-3.

PMID:
24570176
8.

A VLP library of C-terminally truncated Hepatitis B core proteins: correlation of RNA encapsidation with a Th1/Th2 switch in the immune responses of mice.

Sominskaya I, Skrastina D, Petrovskis I, Dishlers A, Berza I, Mihailova M, Jansons J, Akopjana I, Stahovska I, Dreilina D, Ose V, Pumpens P.

PLoS One. 2013 Sep 23;8(9):e75938. doi: 10.1371/journal.pone.0075938. eCollection 2013.

9.

Chimeric derivatives of hepatitis B virus core particles carrying major epitopes of the rubella virus E1 glycoprotein.

Skrastina D, Petrovskis I, Petraityte R, Sominskaya I, Ose V, Lieknina I, Bogans J, Sasnauskas K, Pumpens P.

Clin Vaccine Immunol. 2013 Nov;20(11):1719-28. doi: 10.1128/CVI.00533-13. Epub 2013 Sep 4.

10.

Yeast-expressed bacteriophage-like particles for the packaging of nanomaterials.

Freivalds J, Kotelovica S, Voronkova T, Ose V, Tars K, Kazaks A.

Mol Biotechnol. 2014 Feb;56(2):102-10. doi: 10.1007/s12033-013-9686-0.

PMID:
23852987
11.

Posttranslational modifications and secretion efficiency of immunogenic hepatitis B virus L protein deletion variants.

Niedre-Otomere B, Bogdanova A, Bruvere R, Ose V, Gerlich WH, Pumpens P, Glebe D, Kozlovska T.

Virol J. 2013 Feb 25;10:63. doi: 10.1186/1743-422X-10-63.

12.

Recombinant Semliki Forest virus vectors encoding hepatitis B virus small surface and pre-S1 antigens induce broadly reactive neutralizing antibodies.

Niedre-Otomere B, Bogdanova A, Skrastina D, Zajakina A, Bruvere R, Ose V, Gerlich WH, Garoff H, Pumpens P, Glebe D, Kozlovska T.

J Viral Hepat. 2012 Sep;19(9):664-73. doi: 10.1111/j.1365-2893.2012.01594.x. Epub 2012 May 17.

PMID:
22863271
13.

Fibronectin-binding nanoparticles for intracellular targeting addressed by B. burgdorferi BBK32 protein fragments.

Ranka R, Petrovskis I, Sominskaya I, Bogans J, Bruvere R, Akopjana I, Ose V, Timofejeva I, Brangulis K, Pumpens P, Baumanis V.

Nanomedicine. 2013 Jan;9(1):65-73. doi: 10.1016/j.nano.2012.05.003. Epub 2012 May 23.

PMID:
22633898
14.

Potato virus Y-like particles as a new carrier for the presentation of foreign protein stretches.

Kalnciema I, Skrastina D, Ose V, Pumpens P, Zeltins A.

Mol Biotechnol. 2012 Oct;52(2):129-39. doi: 10.1007/s12033-011-9480-9.

PMID:
22167454
15.

Highly efficient production of phosphorylated hepatitis B core particles in yeast Pichia pastoris.

Freivalds J, Dislers A, Ose V, Pumpens P, Tars K, Kazaks A.

Protein Expr Purif. 2011 Feb;75(2):218-24. doi: 10.1016/j.pep.2010.09.010. Epub 2010 Sep 18.

PMID:
20854910
16.

Construction and immunological evaluation of multivalent hepatitis B virus (HBV) core virus-like particles carrying HBV and HCV epitopes.

Sominskaya I, Skrastina D, Dislers A, Vasiljev D, Mihailova M, Ose V, Dreilina D, Pumpens P.

Clin Vaccine Immunol. 2010 Jun;17(6):1027-33. doi: 10.1128/CVI.00468-09. Epub 2010 Apr 21.

17.

Versatile virus-like particle carrier for epitope based vaccines.

Tissot AC, Renhofa R, Schmitz N, Cielens I, Meijerink E, Ose V, Jennings GT, Saudan P, Pumpens P, Bachmann MF.

PLoS One. 2010 Mar 23;5(3):e9809. doi: 10.1371/journal.pone.0009809.

18.

Assembly of mixed rod-like and spherical particles from group I and II RNA bacteriophage coat proteins.

Rumnieks J, Ose V, Tars K, Dislers A, Strods A, Cielens I, Renhofa R.

Virology. 2009 Sep 1;391(2):187-94. doi: 10.1016/j.virol.2009.06.023. Epub 2009 Jul 14.

19.

Melanoma vaccine candidates from chimeric hepatitis B core virus-like particles carrying a tumor-associated MAGE-3 epitope.

Kazaks A, Balmaks R, Voronkova T, Ose V, Pumpens P.

Biotechnol J. 2008 Nov;3(11):1429-36. doi: 10.1002/biot.200800160.

PMID:
18956370
20.

High immunogenicity of a hydrophilic component of the hepatitis B virus preS1 sequence exposed on the surface of three virus-like particle carriers.

Skrastina D, Bulavaite A, Sominskaya I, Kovalevska L, Ose V, Priede D, Pumpens P, Sasnauskas K.

Vaccine. 2008 Apr 7;26(16):1972-81. doi: 10.1016/j.vaccine.2008.02.030. Epub 2008 Feb 26.

PMID:
18343539
21.

Proteasomal degradation of core protein variants from chronic hepatitis B patients.

Braun S, Zajakina A, Aleksejeva J, Sharipo A, Bruvere R, Ose V, Pumpens P, Garoff H, Meisel H, Kozlovska T.

J Med Virol. 2007 Sep;79(9):1312-21.

PMID:
17607782
22.

Dynamics of magnetotactic bacteria in a rotating magnetic field.

Erglis K, Wen Q, Ose V, Zeltins A, Sharipo A, Janmey PA, Cēbers A.

Biophys J. 2007 Aug 15;93(4):1402-12. Epub 2007 May 25.

23.

Hamster polyomavirus-derived virus-like particles are able to transfer in vitro encapsidated plasmid DNA to mammalian cells.

Voronkova T, Kazaks A, Ose V, Ozel M, Scherneck S, Pumpens P, Ulrich R.

Virus Genes. 2007 Jun;34(3):303-14. Epub 2006 Aug 22.

PMID:
16927120
24.

Recombinant virus-like particles as a carrier of B- and T-cell epitopes of hepatitis C virus (HCV).

Mihailova M, Boos M, Petrovskis I, Ose V, Skrastina D, Fiedler M, Sominskaya I, Ross S, Pumpens P, Roggendorf M, Viazov S.

Vaccine. 2006 May 15;24(20):4369-77. Epub 2006 Mar 15.

PMID:
16574285
25.

Assembly of bacteriophage Qbeta virus-like particles in yeast Saccharomyces cerevisiae and Pichia pastoris.

Freivalds J, Dislers A, Ose V, Skrastina D, Cielens I, Pumpens P, Sasnauskas K, Kazaks A.

J Biotechnol. 2006 May 29;123(3):297-303. Epub 2006 Jan 6.

PMID:
16406160
26.

Mosaic hepatitis B virus core particles presenting the complete preS sequence of the viral envelope on their surface.

Kazaks A, Borisova G, Cvetkova S, Kovalevska L, Ose V, Sominskaya I, Pumpens P, Skrastina D, Dislers A.

J Gen Virol. 2004 Sep;85(Pt 9):2665-70.

PMID:
15302960
27.

Comparison of biomechanical and structural properties between human aortic and pulmonary valve.

Stradins P, Lacis R, Ozolanta I, Purina B, Ose V, Feldmane L, Kasyanov V.

Eur J Cardiothorac Surg. 2004 Sep;26(3):634-9.

PMID:
15302062
28.

An amino-terminal segment of hantavirus nucleocapsid protein presented on hepatitis B virus core particles induces a strong and highly cross-reactive antibody response in mice.

Geldmacher A, Skrastina D, Petrovskis I, Borisova G, Berriman JA, Roseman AM, Crowther RA, Fischer J, Musema S, Gelderblom HR, Lundkvist A, Renhofa R, Ose V, Krüger DH, Pumpens P, Ulrich R.

Virology. 2004 May 20;323(1):108-19.

29.

Biomechanical properties of oesophagus wall under loading.

Vanags I, Petersons A, Ose V, Ozolanta I, Kasyanov V, Laizans J, Vjaters E, Gardovskis J, Vanags A.

J Biomech. 2003 Sep;36(9):1387-90.

PMID:
12893048
30.

Stop codon insertion restores the particle formation ability of hepatitis B virus core-hantavirus nucleocapsid protein fusions.

Kazaks A, Lachmann S, Koletzki D, Petrovskis I, Dislers A, Ose V, Skrastina D, Gelderblom HR, Lundkvist A, Meisel H, Borisova G, Krüger DH, Pumpens P, Ulrich R.

Intervirology. 2002;45(4-6):340-9.

PMID:
12602354
31.

Chimeric bacteriophage fr virus-like particles harboring the immunodominant C-terminal region of hamster polyomavirus VP1 induce a strong VP1-specific antibody response in rabbits and mice.

Voronkova T, Grosch A, Kazaks A, Ose V, Skrastina D, Sasnauskas K, Jandrig B, Arnold W, Scherneck S, Pumpens P, Ulrich R.

Viral Immunol. 2002;15(4):627-43.

PMID:
12513932
32.

Evaluation of HBs, HBc, and frCP virus-like particles for expression of human papillomavirus 16 E7 oncoprotein epitopes.

Pumpens P, Razanskas R, Pushko P, Renhof R, Gusars I, Skrastina D, Ose V, Borisova G, Sominskaya I, Petrovskis I, Jansons J, Sasnauskas K.

Intervirology. 2002;45(1):24-32.

PMID:
11937768
33.

Mutilation of RNA phage Qbeta virus-like particles: from icosahedrons to rods.

Cielens I, Ose V, Petrovskis I, Strelnikova A, Renhofa R, Kozlovska T, Pumpens P.

FEBS Lett. 2000 Oct 6;482(3):261-4.

34.

Behavior of a short preS1 epitope on the surface of hepatitis B core particles.

Borisova G, Borschukova O, Skrastina D, Dislers A, Ose V, Pumpens P, Grens E.

Biol Chem. 1999 Mar;380(3):315-24.

PMID:
10223334
35.

Mosaic Qbeta coats as a new presentation model.

Vasiljeva I, Kozlovska T, Cielens I, Strelnikova A, Kazaks A, Ose V, Pumpens P.

FEBS Lett. 1998 Jul 10;431(1):7-11.

36.

New isolate of Macosoma neustria nuclear polyhedrosis virus in Latvia.

Jankevica L, Cudare Z, Ose V.

J Invertebr Pathol. 1998 May;71(3):283-5. No abstract available.

PMID:
9538036
37.

Short synthetic CDR-peptides forming the antibody combining site of the monoclonal antibody against RNA bacteriophage fr neutralize the phage activity.

Steinbergs J, Kilchewska K, Lazdina U, Dishlers A, Ose V, Sällberg M, Tsimanis A.

Hum Antibodies Hybridomas. 1996;7(3):106-12.

PMID:
9057058
38.

RNA phage Q beta coat protein as a carrier for foreign epitopes.

Kozlovska TM, Cielens I, Vasiljeva I, Strelnikova A, Kazaks A, Dislers A, Dreilina D, Ose V, Gusars I, Pumpens P.

Intervirology. 1996;39(1-2):9-15. Review.

PMID:
8957664
39.

Three-dimensional structure of hepatitis B virus core particles determined by electron cryomicroscopy.

Crowther RA, Kiselev NA, Böttcher B, Berriman JA, Borisova GP, Ose V, Pumpens P.

Cell. 1994 Jun 17;77(6):943-50.

PMID:
8004680
40.

Recombinant RNA phage Q beta capsid particles synthesized and self-assembled in Escherichia coli.

Kozlovska TM, Cielens I, Dreilinņa D, Dislers A, Baumanis V, Ose V, Pumpens P.

Gene. 1993 Dec 27;137(1):133-7.

PMID:
7506687
41.

Analysis of RNA phage fr coat protein assembly by insertion, deletion and substitution mutagenesis.

Pushko P, Kozlovskaya T, Sominskaya I, Brede A, Stankevica E, Ose V, Pumpens P, Grens E.

Protein Eng. 1993 Nov;6(8):883-91.

PMID:
8309936
42.

Crystallization of bacteriophage fr and its recombinant capsids.

Bundule M, Pumpens P, Ose V, Valegård K, Liljas L.

J Mol Biol. 1993 Aug 5;232(3):1005-6.

PMID:
8355265
43.

[Detection of HTLV-I virus in patients with myeloproliferative hemoblastoses].

Kukaĭn RA, Murovska MF, Mullere IV, Vinkele RA, Tkachenko TI, Ose VP, Pashkute MK, Kalnberza GK, Grasmane DV, Teĭlane II.

Vopr Onkol. 1993;39(1-3):44-9. Russian.

PMID:
8073675
44.

Immunogenicity of recombinant core particles of hepatitis B virus containing epitopes of human immunodeficiency virus 1 core antigen.

Ulrich R, Borisova GP, Gren E, Berzin I, Pumpen P, Eckert R, Ose V, Siakkou H, Gren EJ, von Baehr R, et al.

Arch Virol. 1992;126(1-4):321-8.

PMID:
1381912
45.

[Exposure of the major immunodominant epitope of the gp51 envelope protein of bovine leukosis virus on the surface of the hepatitis B core antigen capsid].

Ul'rikh R, Borisova GP, Siakkou Kh, Plattser K, Ose VP, Berzin' IG, Dreĭlinia DE, Pushko PM, Tsibinogin VV, Pumpen PP, et al.

Mol Biol (Mosk). 1991 Mar-Apr;25(2):368-74. Russian.

PMID:
1715509
46.

[Exposition of epitopes of transmembrane protein gp41 of the human immunodeficiency virus on surface capsids of the hepatitis B virus core antigen].

Yl'rikh R, Borisova GP, Mering R, Létch I, Ose VP, Berzin' IG, Dreĭlinia DE, Pushko PM, Tsibinogin VV, Pumpen PP, et al.

Bioorg Khim. 1990 Sep;16(9):1283-6. Russian. No abstract available.

PMID:
1706924
47.

[The expression of the human interleukin-2 gene in Escherichia coli bacteria].

Avot AIa, Bundulis IuP, Ose VIa, Romanchikova NV, Skrivelis VA, Iankevits cEK, Tsimanis AIu, Gren EIa.

Dokl Akad Nauk SSSR. 1990;315(4):994-6. Russian. No abstract available.

PMID:
2097141
48.

[Hepatitis B core antigen as a carrier of functionally active epitopes: exposure of pre-S sites on capsids].

Borisova GP, Berzin' IG, Tsibinogin VV, Loseva VIa, Pushko PM, Ose VP, Dreĭlina DE, Pumpen PP, Gren EIa.

Dokl Akad Nauk SSSR. 1990;312(3):751-4. Russian. No abstract available.

PMID:
1699713
49.

Recombinant core particles of hepatitis B virus exposing foreign antigenic determinants on their surface.

Borisova GP, Berzins I, Pushko PM, Pumpen P, Gren EJ, Tsibinogin VV, Loseva V, Ose V, Ulrich R, Siakkou H, et al.

FEBS Lett. 1989 Dec 18;259(1):121-4.

50.

[Detection of viral particles in the blood lymphocytes of a patient with T-cell acute lymphoblastic leukemia].

Kukaĭn RA, Nagaeva LI, Kalnberza IV, Ose VP, Mamaeva SE.

Eksp Onkol. 1988;10(3):44-7. Russian.

PMID:
2842123

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