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Items: 10

1.

Design and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonists.

Burkholder TP, Cunningham BE, Clayton JR, Lander PA, Brown ML, Doti RA, Durst GL, Montrose-Rafizadeh C, King C, Osborne HE, Amos RM, Zink RW, Stramm LE, Burris TP, Cardona G, Konkol DL, Reidy C, Christe ME, Genin MJ.

Bioorg Med Chem Lett. 2015 Apr 1;25(7):1377-80. doi: 10.1016/j.bmcl.2015.02.062. Epub 2015 Mar 3.

PMID:
25752984
2.

Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method.

Dai SY, Chalmers MJ, Bruning J, Bramlett KS, Osborne HE, Montrose-Rafizadeh C, Barr RJ, Wang Y, Wang M, Burris TP, Dodge JA, Griffin PR.

Proc Natl Acad Sci U S A. 2008 May 20;105(20):7171-6. doi: 10.1073/pnas.0710802105. Epub 2008 May 12.

3.

Benzopyrans are selective estrogen receptor beta agonists with novel activity in models of benign prostatic hyperplasia.

Norman BH, Dodge JA, Richardson TI, Borromeo PS, Lugar CW, Jones SA, Chen K, Wang Y, Durst GL, Barr RJ, Montrose-Rafizadeh C, Osborne HE, Amos RM, Guo S, Boodhoo A, Krishnan V.

J Med Chem. 2006 Oct 19;49(21):6155-7.

PMID:
17034120
4.

The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand.

Burris TP, Montrose C, Houck KA, Osborne HE, Bocchinfuso WP, Yaden BC, Cheng CC, Zink RW, Barr RJ, Hepler CD, Krishnan V, Bullock HA, Burris LL, Galvin RJ, Bramlett K, Stayrook KR.

Mol Pharmacol. 2005 Mar;67(3):948-54. Epub 2004 Dec 15.

PMID:
15602004
5.

The selective estrogen receptor modulator trioxifene (LY133314) inhibits metastasis and extends survival in the PAIII rat prostatic carcinoma model.

Neubauer BL, McNulty AM, Chedid M, Chen K, Goode RL, Johnson MA, Jones CD, Krishnan V, Lynch R, Osborne HE, Graff JR.

Cancer Res. 2003 Sep 15;63(18):6056-62.

6.

Substrate specificity of isopenicillin N synthase.

Huffman GW, Gesellchen PD, Turner JR, Rothenberger RB, Osborne HE, Miller FD, Chapman JL, Queener SW.

J Med Chem. 1992 May 15;35(10):1897-914.

PMID:
1588566
7.

Design and implementation of a particle concentration fluorescence method for the detection of HIV-1 protease inhibitors.

Manetta JV, Lai MH, Osborne HE, Dee A, Margolin N, Sportsman JR, Vlahos CJ, Yan SB, Heath WF.

Anal Biochem. 1992 Apr;202(1):10-5.

PMID:
1621970
8.

Glucose transporter levels in tissues of spontaneously diabetic Zucker fa/fa rat (ZDF/drt) and viable yellow mouse (Avy/a).

Slieker LJ, Sundell KL, Heath WF, Osborne HE, Bue J, Manetta J, Sportsman JR.

Diabetes. 1992 Feb;41(2):187-93.

PMID:
1733808
9.

Bis-trimethylsilylcefamandole: an unusually stable trimethylsilyl-intermediate.

Wheeler WJ, Finley DR, Osborne HE.

J Antibiot (Tokyo). 1980 Jan;33(1):72-5.

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